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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta receptor complex assembly
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Accession:GO:0007181 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.
Synonyms:exact_synonym: TGF-beta receptor complex assembly;   TGF-beta:type II receptor:type I receptor complex assembly;   TGFbeta receptor complex assembly



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transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IDA TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,217...83,542,262 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IMP RGD PMID:8106553 RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    response to stimulus 10416
      response to endogenous stimulus 2060
        cellular response to endogenous stimulus 1639
          cellular response to transforming growth factor beta stimulus 275
            transforming growth factor beta receptor signaling pathway 193
              transforming growth factor beta receptor complex assembly 3
Path 2
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological process 12866
        regulation of cellular process 12336
          signal transduction 6908
            cell surface receptor signaling pathway 2801
              enzyme linked receptor protein signaling pathway 985
                transmembrane receptor protein serine/threonine kinase signaling pathway 395
                  transforming growth factor beta receptor signaling pathway 193
                    transforming growth factor beta receptor complex assembly 3
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