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ONTOLOGY REPORT - ANNOTATIONS

Term:transforming growth factor beta receptor signaling pathway
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Accession:GO:0007179 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: TGF-beta receptor signaling pathway;   TGF-beta receptor signalling pathway;   TGFbeta receptor signaling pathway;   TGFbeta receptor signalling pathway;   transforming growth factor beta receptor signalling pathway
 only_in_taxon: NCBITaxon:33511 ! Deuterostomia


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transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
IMP		 (PMID:8242742)
(PMID:11376112)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
PMID:12968668		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:8242742 PMID:11376112 PMID:12968668 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:8554636 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Acvrl1 activin A receptor like type 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:15702480)
GO_REF:0000033
(PMID:14580334)		 RGD
GO_Central		 PMID:14580334 PMID:15702480 GO_REF:0000033 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO
IBA		 (PMID:11955914)
GO_REF:0000033
(MGI:3828410|PMID:11955914)		 RGD
GO_Central		 PMID:11955914 GO_REF:0000033 MGI:3828410 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 acts_upstream_of_or_within IDA PMID:11376112 MGI PMID:11376112 RGD:8554753 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258 		JBrowse link
G Apoa1 apolipoprotein A1 NOT|involved_in ISO (PMID:23726972) RGD PMID:23726972 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:26583432) RGD PMID:26583432 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:26583432) RGD PMID:26583432 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO
IEA		 (PMID:12958365)
GO_REF:0000107		 RGD
Ensembl		 PMID:12958365 GO_REF:0000107 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in IEP
IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central
RGD		 PMID:12933693 GO_REF:0000033 GO_REF:0000118, RGD:632261 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:36641752) RGD PMID:36641752 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cav2 caveolin 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:98728 (PMID:21832243)		 Ensembl
RGD		 PMID:21832243 GO_REF:0000107 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:14505427 RGD:1582324 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cdc45 cell division cycle 45 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:21168935) RGD PMID:21168935 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:3768254 (PMID:16079159)		 Ensembl
RGD		 PMID:16079159 GO_REF:0000107 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in ISO (PMID:9707553) RGD PMID:9707553 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO (PMID:16619037) RGD PMID:16619037 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:21168935) RGD PMID:21168935 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Col1a2 collagen type I alpha 2 chain involved_in ISO
IEA		 (PMID:17217948)
GO_REF:0000107		 RGD
Ensembl		 PMID:17217948 GO_REF:0000107 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain involved_in ISO (PMID:16360482) RGD PMID:16360482 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Dab2 DAB adaptor protein 2 involved_in ISO
IEA		 (PMID:11387212)
GO_REF:0000107		 RGD
Ensembl		 PMID:11387212 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (PMID:12138158) RGD PMID:12138158 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Eng endoglin involved_in
NOT|involved_in		 ISO
IBA		 (PMID:18223685)
GO_REF:0000033
(PMID:8294451)
(PMID:12015308)		 RGD
GO_Central		 PMID:8294451 PMID:12015308 PMID:18223685 GO_REF:0000033 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within ISO (PMID:28106121) RGD PMID:28106121 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:21325030) RGD PMID:21325030 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Flcn folliculin acts_upstream_of ISO MGI:4348628 (PMID:21258407) RGD PMID:21258407 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO
IBA		 (MGI:1321467|PMID:9858566), (MGI:1328655|PMID:10349617), (MGI:3055632|PMID:15363409)
GO_REF:0000033		 RGD
GO_Central		 PMID:9858566 PMID:10349617 PMID:15363409 GO_REF:0000033 MGI:1321467 MGI:1328655 MGI:3055632 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049 		JBrowse link
G Fshb follicle stimulating hormone subunit beta involved_in ISO (PMID:14557487) RGD PMID:14557487 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fut8 fucosyltransferase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3608699 (PMID:16236725)		 Ensembl
RGD		 PMID:16236725 GO_REF:0000107 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO
IBA		 (PMID:21750175)
GO_REF:0000033
(MGI:5545971|PMID:21750175)		 RGD
GO_Central		 PMID:21750175 GO_REF:0000033 MGI:5545971 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:4829764 (PMID:20530870)		 Ensembl
RGD		 PMID:20530870 GO_REF:0000107 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:3487301 (PMID:17159989) RGD PMID:17159989 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase involved_in ISO
ISS		 (PMID:15574495)
GO_REF:0000024		 RGD
UniProt		 PMID:15574495 GO_REF:0000024 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Itga8 integrin subunit alpha 8 acts_upstream_of ISO MGI:107430|MGI:2181699 (PMID:17537792) RGD PMID:17537792 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Itgb1 integrin subunit beta 1 NOT|involved_in ISO (PMID:24036928)
(MGI:5582864|PMID:24036928)		 RGD PMID:24036928 MGI:5582864 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb5 integrin subunit beta 5 involved_in ISO (PMID:24036928)
(MGI:5582864|PMID:24036928)		 RGD PMID:24036928 MGI:5582864 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472 		JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO MGI:1338035|MGI:1926484 (PMID:12634787), (PMID:30952606) RGD PMID:12634787 PMID:30952606 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671 		JBrowse link
G Itgb8 integrin subunit beta 8 acts_upstream_of_or_within ISO MGI:96615 (PMID:30952606) RGD PMID:30952606 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lpxn leupaxin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084 		JBrowse link
G Lrrc32 leucine rich repeat containing 32 involved_in ISO (PMID:19750484) RGD PMID:19750484 NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 NAS RGD PMID:10028916 RGD:68276 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within
involved_in		 ISO MGI:2180017|PR:P04202 (PMID:12379497), (PMID:7730318)
(PMID:18672106)		 RGD PMID:7730318 PMID:12379497 PMID:18672106 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 acts_upstream_of_or_within ISO MGI:2388061 (PMID:12208849) RGD PMID:12208849 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO MGI:2676654 (PMID:12941696) RGD PMID:12941696 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:16145668) RGD PMID:16145668 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mir143 microRNA 143 acts_upstream_of_or_within ISO MGI:2676830|MGI:5531026 (PMID:29925839) RGD PMID:29925839 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir145 microRNA 145 acts_upstream_of_or_within ISO MGI:2676828|MGI:5531026 (PMID:29925839) RGD PMID:29925839 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir183 microRNA 183 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir212 microRNA 212 involved_in ISO (PMID:25217442) RGD PMID:25217442 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:20857419) RGD PMID:20857419 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir30a microRNA 30a involved_in ISO (PMID:23960241) RGD PMID:23960241 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mstn myostatin acts_upstream_of_or_within ISO (PMID:12595574) RGD PMID:12595574 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:29715368) RGD PMID:29715368 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nlk nemo like kinase involved_in ISO (PMID:15004007) RGD PMID:15004007 NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (PMID:14511481) RGD PMID:14511481 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Npnt nephronectin acts_upstream_of ISO MGI:3715213 (PMID:17537792) RGD PMID:17537792 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:6192878|PMID:29909984)		 UniProt
GO_Central
Ensembl
RGD		 PMID:29909984 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
G Onecut1 one cut homeobox 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1891408 (PMID:16103213)		 Ensembl
RGD		 PMID:16103213 GO_REF:0000107 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of ISO MGI:1196423 (PMID:16103213) RGD PMID:16103213 NCBI chr18:57,831,647...57,890,884
Ensembl chr18:57,832,111...57,879,629 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 NOT|involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (PMID:15356634) RGD PMID:15356634 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISO (PMID:24036928) RGD PMID:24036928 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptprk protein tyrosine phosphatase, receptor type, K involved_in ISO (PMID:15899872) RGD PMID:15899872 NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605 		JBrowse link
G Pxn paxillin involved_in ISO
IBA
IEA		 (PMID:24036928)
GO_REF:0000033
GO_REF:0000118
(MGI:5582864|PMID:24036928)		 RGD
GO_Central
TreeGrafter		 PMID:24036928 GO_REF:0000033 GO_REF:0000118 MGI:5582864 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931 		JBrowse link
G Selenon selenoprotein N acts_upstream_of_or_within ISO (PMID:28106121) RGD PMID:28106121 NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23960241) RGD PMID:23960241 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:98725|MGI:98834 (PMID:18212064) RGD PMID:18212064 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Smad1 SMAD family member 1 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
(PMID:9389648)		 Ensembl
GO_Central
TreeGrafter
RGD		 PMID:9389648 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad2 SMAD family member 2 involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO
IEA
IMP		 GO_REF:0000024
GO_REF:0000033
MGI:894293|MGI:98725|MGI:98834 (PMID:11557747), (PMID:14749725), (PMID:18212064)
GO_REF:0000118
(PMID:18548003), (PMID:8752209), (PMID:8980228), (PMID:9311995), (PMID:9389648), (PMID:9732876)
PMID:22073128		 UniProt
GO_Central
RGD
TreeGrafter		 PMID:8752209 PMID:8980228 PMID:9311995 PMID:9389648 PMID:9732876 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000118, RGD:8554355 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 involved_in
acts_upstream_of_or_within		 IMP
IBA
ISO
IEA		 GO_REF:0000033
(PMID:10823886), (PMID:18548003), (PMID:21947082), (PMID:28467929), (PMID:8774881), (PMID:9311995), (PMID:9732876)
(PMID:15239668), (PMID:16619037), (PMID:21937600)
GO_REF:0000118
PMID:22073128
TGFbeta-1 dependent, in pancreatic stellate cells		 GO_Central
RGD
TreeGrafter		 PMID:8774881 PMID:9311995 PMID:9732876 PMID:10823886 PMID:15239668 More... GO_REF:0000033 GO_REF:0000118, RGD:1625706, RGD:8554355, RGD:2300404 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
RNAcentral:URS0000554A4F_9606 (PMID:10823886), (PMID:22821565), (PMID:23221074), (PMID:25514493), (PMID:8774881), (PMID:9311995), (PMID:9389648), (PMID:9732876)
MGI:108051|MGI:98725|MGI:98834 (PMID:18212064)
GO_REF:0000118
(MGI:3769957|PMID:16330325)		 Ensembl
GO_Central
RGD
TreeGrafter		 PMID:8774881 PMID:9311995 PMID:9389648 PMID:9732876 PMID:10823886 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3769957 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad5 SMAD family member 5 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000118
GO_REF:0000033
(PMID:11376112)		 TreeGrafter
GO_Central
RGD		 PMID:11376112 GO_REF:0000033 GO_REF:0000118 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634 		JBrowse link
G Smad6 SMAD family member 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Smad7 SMAD family member 7 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:11557747)
GO_REF:0000118		 Ensembl
GO_Central
RGD
TreeGrafter		 PMID:11557747 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smad9 SMAD family member 9 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6453080|PMID:31314592) RGD PMID:31314592 MGI:6453080 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:24036928) RGD PMID:24036928 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 UniProtKB:P01137 (PMID:28467929)
GO_REF:0000107		 RGD
Ensembl		 PMID:28467929 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 acts_upstream_of_or_within ISO MGI:2667182 (PMID:12464436) RGD PMID:12464436 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEP		 GO_REF:0000024
UniProtKB:P36897 (PMID:11157754), (PMID:15334054), (PMID:18453574), (PMID:18625725), (PMID:19736306), (PMID:22714950), (PMID:25196641), (PMID:26572508), (PMID:26908446), (PMID:27693460), (PMID:28373289), (PMID:28467929), (PMID:31023188), (PMID:31368162), (PMID:32644293), (PMID:9389648)
(PMID:12208849), (PMID:23868260)
GO_REF:0000033
(MGI:2663364|PMID:12773577), (MGI:67103|PMID:8009224)		 UniProt
RGD
GO_Central		 PMID:8009224 PMID:9389648 PMID:11157754 PMID:12208849 PMID:12773577 More... GO_REF:0000024 GO_REF:0000033 MGI:2663364 MGI:67103, RGD:127229954 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:2663364|PMID:12773577)
(PMID:11157754), (PMID:17192487), (PMID:18223299), (PMID:18358889)		 AgBase
GO_Central
TreeGrafter
RGD		 PMID:11157754 PMID:12773577 PMID:17192487 PMID:18223299 PMID:18358889 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:2663364 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:2683382|PMID:14691138)
(PMID:11157754), (PMID:18718461)		 AgBase
GO_Central
RGD		 PMID:11157754 PMID:14691138 PMID:18718461 GO_REF:0000024 GO_REF:0000033 MGI:2683382 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA
ISS		 MGI:2386570|MGI:2388050 (PMID:11285230), (PMID:14580334), (PMID:15820682), (PMID:17078885), (PMID:21832243)
GO_REF:0000033
UniProtKB:P01137 (PMID:11157754), (PMID:12065756), (PMID:1333888), (PMID:22714950), (PMID:24978044), (PMID:27693460), (PMID:28251559), (PMID:9311995), (PMID:9389648)
GO_REF:0000107
UniProtKB:P10600 (MGI:3820811|PMID:18718461)
GO_REF:0000024		 RGD
GO_Central
Ensembl
AgBase		 PMID:1333888 PMID:9311995 PMID:9389648 PMID:11157754 PMID:11285230 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3820811, RGD:737663, RGD:2302517, RGD:2302021 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within
involved_in		 TAS
ISO
IBA
IEA
IMP		 MGI:2384513 (PMID:21420963)
GO_REF:0000033
(PMID:12015308), (PMID:1333888), (PMID:18453574), (PMID:24606633), (PMID:28131417), (PMID:9311995)
GO_REF:0000107
(PMID:11157754)		 RGD
GO_Central
Ensembl		 PMID:1333888 PMID:9311995 PMID:11157754 PMID:12015308 PMID:18453574 More... GO_REF:0000033 GO_REF:0000107, RGD:727411, RGD:2302517 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of
involved_in		 TAS
ISO
IBA		 (PMID:25382630)
GO_REF:0000033
(PMID:11157754), (PMID:12958365), (PMID:29130787), (PMID:30467960)
UniProtKB:P27090 (MGI:2663364|PMID:12773577), (MGI:3699491|PMID:17295310), (MGI:3807767|PMID:11546783)		 RGD
GO_Central		 PMID:11157754 PMID:11546783 PMID:12773577 PMID:12958365 PMID:17295310 More... GO_REF:0000033 MGI:2663364 MGI:3699491 MGI:3807767, RGD:729942 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:2,600,874...2,604,211
Ensembl chr12:2,600,934...2,604,222 		JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO MGI:4001992 (PMID:28811219) RGD PMID:28811219 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:108051|MGI:894293|MGI:98725 (PMID:18212064)		 Ensembl
RGD		 PMID:18212064 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21947082)		 Ensembl
RGD		 PMID:21947082 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:19135894) RGD PMID:19135894 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711 		JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:14,896,442...14,898,770
Ensembl chr10:14,896,378...14,899,863 		JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12595574)		 GO_Central
RGD		 PMID:12595574 GO_REF:0000033 NCBI chr10:79,185,563...79,191,657
Ensembl chr10:79,186,647...79,191,657 		JBrowse link
G Zfyve9 zinc finger FYVE-type containing 9 involved_in ISO
IBA		 (PMID:9865696)
GO_REF:0000033		 RGD
GO_Central		 PMID:9865696 GO_REF:0000033 NCBI chr 5:123,370,677...123,529,699
Ensembl chr 5:123,370,677...123,529,699 		JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597 		JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 NOT|involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936 		JBrowse link
G Zyx zyxin involved_in ISO
IBA		 (PMID:24036928)
GO_REF:0000033
(MGI:5582864|PMID:24036928)		 RGD
GO_Central		 PMID:24036928 GO_REF:0000033 MGI:5582864 NCBI chr 4:71,236,767...71,246,553
Ensembl chr 4:71,237,451...71,246,553 		JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA		 (PMID:21170088)
GO_REF:0000107		 RGD
Ensembl		 PMID:21170088 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adamtsl2 ADAMTS-like 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:18677313)
(PMID:25762570)		 RGD PMID:18677313 PMID:25762570 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554 		JBrowse link
G Aspn asporin involved_in ISO (PMID:17827158)
(MGI:3762064|PMID:17827158)		 RGD PMID:17827158 MGI:3762064 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO
IEA		 (PMID:14660579), (PMID:19328798)
GO_REF:0000002		 RGD
InterPro		 PMID:14660579 PMID:19328798 GO_REF:0000002 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bcl9l BCL9 like involved_in ISO
IBA		 (PMID:19328798)
GO_REF:0000033		 RGD
GO_Central		 PMID:19328798 GO_REF:0000033 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 UniProtKB:P01137 (PMID:28467929)
GO_REF:0000107		 RGD
Ensembl		 PMID:28467929 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Cav2 caveolin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98728 (PMID:21832243)		 Ensembl
RGD		 PMID:21832243 GO_REF:0000107 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Cd109 CD109 molecule involved_in ISO (PMID:16754747) RGD PMID:16754747 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194 		JBrowse link
G Cdh3 cadherin 3 acts_upstream_of_or_within_negative_effect ISO (PMID:22696062) RGD PMID:22696062 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3768254 (PMID:16079159)		 Ensembl
RGD		 PMID:16079159 GO_REF:0000107 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:3768618|PMID:17080483) RGD PMID:17080483 MGI:3768618 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cilp cartilage intermediate layer protein involved_in ISO (PMID:29167509) RGD PMID:29167509 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251 		JBrowse link
G Cripto cripto, EGF-CFC family member acts_upstream_of_or_within ISO MGI:95835 (PMID:17991893) RGD PMID:17991893 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308 		JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO MGI:97359 (PMID:14721776) RGD PMID:14721776 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:25100282 RGD:9685289 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,274...83,539,599 JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in ISO
IBA
IEA		 (MGI:5486566|PMID:12646588)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:12646588 GO_REF:0000033 GO_REF:0000118 MGI:5486566 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Gdf15 growth differentiation factor 15 involved_in ISO (PMID:25893289) RGD PMID:25893289 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4829764 (PMID:20530870)		 Ensembl
RGD		 PMID:20530870 GO_REF:0000107 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98658 (PMID:17991893)		 Ensembl
RGD		 PMID:17991893 GO_REF:0000107 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Htra1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:14973287)		 Ensembl
RGD		 PMID:14973287 GO_REF:0000107 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Htra3 HtrA serine peptidase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3046453|PMID:15206957)		 UniProt
RGD		 PMID:15206957 GO_REF:0000024 MGI:3046453 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315 		JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556 		JBrowse link
G Ints9 integrator complex subunit 9 involved_in ISO (PMID:36641752) RGD PMID:36641752 NCBI chr15:39,200,541...39,284,858
Ensembl chr15:39,200,553...39,303,189 		JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO
IBA		 (MGI:5583005|PMID:24627487)
GO_REF:0000033
(PMID:24627487)		 RGD
GO_Central		 PMID:24627487 GO_REF:0000033 MGI:5583005 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238 		JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:56,415,053...56,499,047
Ensembl chr 7:56,305,448...56,502,474 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO UniProtKB:P01137 (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Mecom MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) RGD PMID:15897867 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590 		JBrowse link
G Mir101-2 microRNA 101-2 involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir106a microRNA 106a involved_in ISO UniProtKB:P37173 (PMID:22912877) RGD PMID:22912877 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661 		JBrowse link
G Mir140 microRNA 140 involved_in ISO (PMID:23401231) RGD PMID:23401231 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir142 microRNA 142 involved_in ISO (PMID:24558198), (PMID:26572508) RGD PMID:24558198 PMID:26572508 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir145 microRNA 145 involved_in ISO UniProtKB:P01137 (PMID:25323858) RGD PMID:25323858 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:22714950) RGD PMID:22714950 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Mir18a microRNA 18a involved_in ISO (PMID:21145484), (PMID:28131417) RGD PMID:21145484 PMID:28131417 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:22821565) RGD PMID:22821565 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mir19a microRNA 19a involved_in ISO UniProtKB:Q03167 (PMID:27098600), (PMID:29130787) RGD PMID:27098600 PMID:29130787 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO (PMID:27098600) RGD PMID:27098600 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO (PMID:27098600) RGD PMID:27098600 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Mir204 microRNA 204 involved_in ISO UniProtKB:Q13485 (PMID:23221074) RGD PMID:23221074 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir20a microRNA 20a involved_in
acts_upstream_of		 ISO (PMID:21145484)
UniProtKB:P01137 (PMID:31368162)		 RGD PMID:21145484 PMID:31368162 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:28095798) RGD PMID:28095798 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir295-1 microRNA 295-1 involved_in ISO (PMID:21490602) RGD PMID:21490602 NCBI chr 1:65,962,566...65,962,646
Ensembl chr 1:65,962,566...65,962,646 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:26687115) RGD PMID:26687115 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:26687115) RGD PMID:26687115 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Mir322 microRNA 322 involved_in ISO UniProtKB:Q03167 (PMID:29130787) RGD PMID:29130787 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir323 microRNA 323 involved_in ISO (PMID:26908446) RGD PMID:26908446 NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624 		JBrowse link
G Mir342 microRNA 342 involved_in ISO (PMID:26857067) RGD PMID:26857067 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir361 microRNA 361 involved_in ISO (PMID:31694982) RGD PMID:31694982 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275 		JBrowse link
G Mir490 microRNA 490 involved_in ISO (PMID:26714817) RGD PMID:26714817 NCBI chr 4:65,047,548...65,047,631
Ensembl chr 4:65,047,548...65,047,631 		JBrowse link
G Mir497 microRNA 497 involved_in ISO (PMID:29969696) RGD PMID:29969696 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir9-3 microRNA 9-3 involved_in ISO (PMID:26315535) RGD PMID:26315535 NCBI chr 1:133,440,049...133,440,138 JBrowse link
G Mir93 microRNA 93 involved_in ISO (PMID:24606633) RGD PMID:24606633 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:28251559) RGD PMID:28251559 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mirlet7a1 microRNA let-7a-1 involved_in ISO (PMID:30467960) RGD PMID:30467960 NCBI chr17:16,113,766...16,113,859
Ensembl chr17:16,113,768...16,113,867 		JBrowse link
G Mirlet7b microRNA let-7b involved_in ISO UniProtKB:P36897 (PMID:24978044) RGD PMID:24978044 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mirlet7c2 microRNA let7c-2 involved_in ISO (PMID:30467960) RGD PMID:30467960 NCBI chr 7:116,803,771...116,803,865
Ensembl chr 7:116,803,771...116,803,865 		JBrowse link
G Mirlet7f-1 microRNA let7f-1 involved_in ISO (PMID:28345812) RGD PMID:28345812 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226 		JBrowse link
G Mirlet7f2 microRNA let-7f-2 involved_in ISO (PMID:28345812) RGD PMID:28345812 NCBI chr  X:20,980,632...20,980,714
Ensembl chr  X:20,980,632...20,980,714 		JBrowse link
G Mirlet7g microRNA let-7g involved_in ISO (PMID:24291274) RGD PMID:24291274 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388 		JBrowse link
G Nepn nephrocan involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:31,786,607...31,799,458
Ensembl chr20:31,783,526...31,799,446 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in ISO
IEA		 (PMID:19293183)
GO_REF:0000107		 RGD
Ensembl		 PMID:19293183 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Onecut1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1891408 (PMID:16103213)		 Ensembl
RGD		 PMID:16103213 GO_REF:0000107 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (PMID:16103213) RGD PMID:16103213 NCBI chr18:57,831,647...57,890,884
Ensembl chr18:57,832,111...57,879,629 		JBrowse link
G Ovol2 ovo-like zinc finger 2 involved_in ISO (MGI:6284898|PMID:28455959) RGD PMID:28455959 MGI:6284898 NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359 		JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 acts_upstream_of_or_within_positive_effect ISO (PMID:23687415) RGD PMID:23687415 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA		 (PMID:17327236)
GO_REF:0000107		 RGD
Ensembl		 PMID:17327236 GO_REF:0000107 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Peg10 paternally expressed 10 involved_in ISO (PMID:15611116) RGD PMID:15611116 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:19122240) RGD PMID:19122240 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in ISO
IBA		 (PMID:20129061), (PMID:24627487)
GO_REF:0000033
(MGI:5582164|PMID:20129061)		 RGD
GO_Central		 PMID:20129061 PMID:24627487 GO_REF:0000033 MGI:5582164 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO (PMID:31611175) RGD PMID:31611175 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in
acts_upstream_of_or_within		 ISO (PMID:31023188)
UniProtKB:P01137|UniProtKB:P12643 (PMID:28467929)		 RGD PMID:28467929 PMID:31023188 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IEA		 (PMID:16751101)
GO_REF:0000107		 RGD
Ensembl		 PMID:16751101 GO_REF:0000107 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Prdm16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within		 ISO (PMID:14656887)
MGI:3576024 (PMID:20007998)
(PMID:19049980)		 RGD PMID:14656887 PMID:19049980 PMID:20007998 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601 		JBrowse link
G Rasl11b RAS-like family 11 member B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15239668)		 Ensembl
RGD		 PMID:15239668 GO_REF:0000107 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152 		JBrowse link
G Ryr1 ryanodine receptor 1 IMP RGD PMID:32619649 RGD:329845531 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (MGI:5306300|PMID:17098745)
GO_REF:0000107		 RGD
Ensembl		 PMID:17098745 GO_REF:0000107 MGI:5306300 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Ski Ski proto-oncogene acts_upstream_of_or_within
involved_in		 ISO
IBA		 UniProtKB:P01137 (PMID:15312649)
MGI:1201674 (PMID:21937600)
GO_REF:0000033
(PMID:12874272), (PMID:17054724), (PMID:17469184), (PMID:19049980)		 RGD
GO_Central		 PMID:12874272 PMID:15312649 PMID:17054724 PMID:17469184 PMID:19049980 More... GO_REF:0000033 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Skil SKI-like proto-oncogene involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17469184), (PMID:19383336)
(PMID:15677329)
GO_REF:0000033		 RGD
GO_Central		 PMID:15677329 PMID:17469184 PMID:19383336 GO_REF:0000033 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Skor2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within		 ISO (PMID:16200078)
(PMID:21937600)		 RGD PMID:16200078 PMID:21937600 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342 		JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171), (PMID:26376865) RGD PMID:16550171 PMID:26376865 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:19047146), (PMID:9256479) RGD PMID:9256479 PMID:19047146 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:11278251), (PMID:12151385), (PMID:16601693), (PMID:17438144), (PMID:18762808), (PMID:21791611), (PMID:9256479)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:9256479 PMID:11278251 PMID:12151385 PMID:16601693 PMID:17438144 More... GO_REF:0000024 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:11278251), (PMID:12151385), (PMID:21791611) RGD PMID:11278251 PMID:12151385 PMID:21791611 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in ISO (PMID:19255252), (PMID:21791611) RGD PMID:19255252 PMID:21791611 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488 		JBrowse link
G Snx1 sorting nexin 1 acts_upstream_of_or_within ISO (PMID:15239668) RGD PMID:15239668 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360 		JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196)
(MGI:5545984|PMID:21266196)		 RGD PMID:21266196 MGI:5545984 NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440 		JBrowse link
G Snx6 sorting nexin 6 involved_in ISO (PMID:11279102) RGD PMID:11279102 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414689|PMID:25576668)		 UniProt
RGD		 PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Strap serine/threonine kinase receptor associated protein acts_upstream_of_positive_effect
acts_upstream_of_or_within		 ISO (PMID:23687415)
(PMID:9856985)		 RGD PMID:9856985 PMID:23687415 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:15781469), (PMID:24613385) RGD PMID:15781469 PMID:24613385 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:12071374 RGD:730235 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IDA RGD PMID:10746731 RGD:1579946 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15657445)		 Ensembl
RGD		 PMID:15657445 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO
IEA
ISS		 (PMID:22344298)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22344298 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
G Vasn vasorin involved_in ISO
IBA		 (PMID:15247411), (PMID:21170088)
GO_REF:0000033		 RGD
GO_Central		 PMID:15247411 PMID:21170088 GO_REF:0000033 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357 		JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26039994)		 UniProt
Ensembl
RGD		 PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266 		JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in ISO
IEA		 (PMID:21054789)
GO_REF:0000107		 RGD
Ensembl		 PMID:21054789 GO_REF:0000107 NCBI chr10:14,896,442...14,898,770
Ensembl chr10:14,896,378...14,899,863 		JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in ISO (PMID:21054789) RGD PMID:21054789 NCBI chr10:79,185,563...79,191,657
Ensembl chr10:79,186,647...79,191,657 		JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (PMID:16601693) RGD PMID:16601693 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:25514493)		 UniProt
Ensembl
RGD		 PMID:25514493 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539 		JBrowse link
G Zfp451 zinc finger protein 451 involved_in ISO (PMID:24324267) RGD PMID:24324267 NCBI chr 9:35,985,441...36,040,991
Ensembl chr 9:35,985,443...36,040,652 		JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adissp adipose secreted signaling protein involved_in ISO
IEA		 (PMID:32024300)
GO_REF:0000107		 RGD
Ensembl		 PMID:32024300 GO_REF:0000107 NCBI chr 3:118,364,730...118,378,881
Ensembl chr 3:118,362,363...118,378,838 		JBrowse link
G Axin1 axin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934919 (PMID:16601693)		 Ensembl
RGD		 PMID:16601693 GO_REF:0000107 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in ISO (PMID:16943770) RGD PMID:16943770 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B involved_in ISO (PMID:16943770) RGD PMID:16943770 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3690196|PMID:16619037)		 UniProt
RGD		 PMID:16619037 GO_REF:0000024 MGI:3690196 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Crebbp CREB binding protein involved_in IEA
ISO		 GO_REF:0000107
(PMID:25514493)		 Ensembl
RGD		 PMID:25514493 GO_REF:0000107 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:25514493) RGD PMID:25514493 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fermt1 FERM domain containing kindlin 1 involved_in ISO (MGI:5571208|PMID:24681597) RGD PMID:24681597 MGI:5571208 NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555 		JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
MGI:4348628 (PMID:21258407)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:21258407 GO_REF:0000024 GO_REF:0000033 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) IMP RGD PMID:15194465 RGD:1582619 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO
IEA		 (MGI:3807767|PMID:11546783)
GO_REF:0000107		 RGD
Ensembl		 PMID:11546783 GO_REF:0000107 MGI:3807767 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:26880260 RGD:13504840 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) RGD PMID:14678985 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
IEA
ISS		 (PMID:24613385)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24613385 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Ing2 inhibitor of growth family, member 2 involved_in ISO (PMID:18334480) RGD PMID:18334480 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482 		JBrowse link
G Itga8 integrin subunit alpha 8 acts_upstream_of_or_within ISO MGI:107430|MGI:2181699 (PMID:17537792) RGD PMID:17537792 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:23868260), (PMID:32887674)
MGI:98725 (PMID:23868260)		 RGD PMID:23868260 PMID:32887674 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813 		JBrowse link
G Men1 menin 1 involved_in ISO
IEA		 (PMID:11274402)
GO_REF:0000107		 RGD
Ensembl		 PMID:11274402 GO_REF:0000107 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Mir21 microRNA 21 acts_upstream_of ISO (PMID:31611175) RGD PMID:31611175 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir30b microRNA 30b involved_in ISO (PMID:28977001) RGD PMID:28977001 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Myocd myocardin involved_in IEA
ISO		 GO_REF:0000107
(MGI:3696631|PMID:16224064)		 Ensembl
RGD		 PMID:16224064 GO_REF:0000107 MGI:3696631 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Npnt nephronectin acts_upstream_of_or_within ISO MGI:3715213 (PMID:17537792) RGD PMID:17537792 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Rnf111 ring finger protein 111 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:16601693)		 GO_Central
RGD		 PMID:16601693 GO_REF:0000033 NCBI chr 8:71,103,967...71,180,172
Ensembl chr 8:71,103,973...71,145,070 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISO
IBA
IEA
ISS		 (PMID:25893292)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
UniProt		 PMID:25893292 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:26376865) RGD PMID:26376865 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19328798)		 Ensembl
RGD		 PMID:19328798 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:11278756) RGD PMID:11278756 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO (PMID:18311138)
(MGI:3788958|PMID:18311138)		 RGD PMID:18311138 MGI:3788958 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO
IEA		 (PMID:18762808)
GO_REF:0000107		 RGD
Ensembl		 PMID:18762808 GO_REF:0000107 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within IMP
ISO		 (PMID:25382630) RGD PMID:25382630 PMID:8106553 RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18555217)
(MGI:1270011|PMID:9657149)		 RGD PMID:9657149 PMID:18555217 MGI:1270011 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21791611)		 UniProt
RGD		 PMID:21791611 GO_REF:0000024 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO (PMID:30592286) RGD PMID:30592286 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9, transcription coactivator NOT|involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435 		JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within ISO (PMID:21182936) RGD PMID:21182936 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (PMID:10208746) RGD PMID:10208746 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589 		JBrowse link
G Eng endoglin involved_in IDA
IBA
ISO		 GO_REF:0000033
(PMID:15702480)		 GO_Central
RGD		 PMID:15702480 PMID:17376778 GO_REF:0000033, RGD:2313627 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:5644149|PMID:21649587) RGD PMID:21649587 MGI:5644149 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Gdf2 growth differentiation factor 2 NOT|involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Il17f interleukin 17F involved_in ISO
IEA		 (PMID:11591732)
GO_REF:0000107		 RGD
Ensembl		 PMID:11591732 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482 		JBrowse link
G Itga3 integrin subunit alpha 3 involved_in ISO (PMID:24621570) RGD PMID:24621570 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (MGI:4939579|PMID:21145499) RGD PMID:21145499 MGI:4939579 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (MGI:4939579|PMID:21145499) RGD PMID:21145499 MGI:4939579 NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO MGI:3610732 (PMID:25715398) RGD PMID:25715398 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Nrep neuronal regeneration related protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:14985127)		 GO_Central
RGD		 PMID:14985127 GO_REF:0000033 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member involved_in ISS
ISO		 GO_REF:0000024
(MGI:4939579|PMID:21145499)		 UniProt
RGD		 PMID:21145499 GO_REF:0000024 MGI:4939579 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305 		JBrowse link
G Smad2 SMAD family member 2 involved_in ISO (PMID:14555988) RGD PMID:14555988 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO (PMID:11711431) RGD PMID:11711431 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad7 SMAD family member 7 IDA RGD PMID:11959632 RGD:625758 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISO (PMID:20624318) RGD PMID:20624318 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:2,600,874...2,604,211
Ensembl chr12:2,600,934...2,604,222 		JBrowse link
G Trim33 tripartite motif-containing 33 involved_in ISO (PMID:19135894) RGD PMID:19135894 NCBI chr 2:190,812,329...190,892,663
Ensembl chr 2:190,807,243...190,888,814 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1201674 (PMID:16824956)		 Ensembl
RGD		 PMID:16824956 GO_REF:0000107 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (PMID:21337521)
(MGI:4940410|PMID:21317240)		 RGD PMID:21317240 PMID:21337521 MGI:4940410 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO
ISS
IEA		 (PMID:2022183), (PMID:8617200)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:2022183 PMID:8617200 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349 		JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6192878|PMID:29909984)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29909984 GO_REF:0000024 GO_REF:0000107 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IDA TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,274...83,539,599 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IMP RGD PMID:8106553 RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10920
      response to endogenous stimulus 2221
        cellular response to endogenous stimulus 1778
          cellular response to growth factor stimulus 882
            cellular response to transforming growth factor beta stimulus 338
              transforming growth factor beta receptor signaling pathway 242
                negative regulation of transforming growth factor beta receptor signaling pathway + 117
                positive regulation of transforming growth factor beta receptor signaling pathway 34
                regulation of transforming growth factor beta receptor signaling pathway + 169
                transforming growth factor beta receptor complex assembly 3
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of cellular process 12748
          signal transduction 7209
            cell surface receptor signaling pathway 2886
              enzyme-linked receptor protein signaling pathway 1053
                cell surface receptor protein serine/threonine kinase signaling pathway 434
                  transforming growth factor beta receptor superfamily signaling pathway 398
                    transforming growth factor beta receptor signaling pathway 242
                      negative regulation of transforming growth factor beta receptor signaling pathway + 117
                      positive regulation of transforming growth factor beta receptor signaling pathway 34
                      regulation of transforming growth factor beta receptor signaling pathway + 169
                      transforming growth factor beta receptor complex assembly 3
paths to the root