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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta receptor signaling pathway
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Accession:GO:0007179 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: TGF-beta receptor signaling pathway;   TGF-beta receptor signalling pathway;   TGFbeta receptor signaling pathway;   TGFbeta receptor signalling pathway;   transforming growth factor beta receptor signalling pathway
 only_in_taxon: NCBITaxon:33511 ! Deuterostomia



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transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in
acts_upstream_of_or_within
ISO
IMP
IBA
(PMID:8242742)
(MGI:1935017|PMID:11376112)
PMID:12968668
PMID:21873635
RGD PMID:8242742 PMID:11376112 PMID:12968668 PMID:21873635 MGI:1935017, RGD:8554636, RGD:13792537 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Acvrl1 activin A receptor like type 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:15702480)
(MGI:2679137|PMID:14580334)
RGD PMID:14580334 PMID:15702480 PMID:21873635 MGI:2679137, RGD:13792537 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO
IBA
(PMID:11955914)
(MGI:3828410|PMID:11955914)
PMID:21873635
RGD PMID:11955914 PMID:21873635 MGI:3828410, RGD:13792537 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 acts_upstream_of_or_within IDA PMID:11376112 MGI PMID:11376112 RGD:8554753 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258
JBrowse link
G Apoa1 apolipoprotein A1 NOT|involved_in ISO (PMID:23726972) RGD PMID:23726972 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:26583432) RGD PMID:26583432 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:26583432) RGD PMID:26583432 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:12958365) RGD PMID:12958365 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:12933693 PMID:21873635 RGD:632261, RGD:13792537 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Cav2 caveolin 2 acts_upstream_of
involved_in
ISO
IEA
MGI:98728 (MGI:5298182|PMID:21832243)
GO_REF:0000107
RGD
Ensembl
PMID:21832243 GO_REF:0000107 MGI:5298182 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:14505427 RGD:1582324 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cdc45 cell division cycle 45 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:21168935) RGD PMID:21168935 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in ISO (PMID:9707553) RGD PMID:9707553 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO (MGI:3690196|PMID:16619037) RGD PMID:16619037 MGI:3690196 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:21168935) RGD PMID:21168935 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Col1a2 collagen type I alpha 2 chain involved_in ISO
IEA
(PMID:17217948)
GO_REF:0000107
RGD
Ensembl
PMID:17217948 GO_REF:0000107 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain involved_in ISO (PMID:16360482) RGD PMID:16360482 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (MGI:2387732|PMID:12138158) RGD PMID:12138158 MGI:2387732 NCBI chr17:33,780,980...33,831,540
Ensembl chr17:33,780,981...33,831,321
JBrowse link
G Eng endoglin involved_in
NOT|involved_in
IBA
ISO
PMID:21873635
(PMID:8294451)
(PMID:18223685)
(PMID:12015308)
RGD PMID:8294451 PMID:12015308 PMID:18223685 PMID:21873635 RGD:13792537 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:21325030) RGD PMID:21325030 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Flcn folliculin acts_upstream_of ISO MGI:4348628 (MGI:5050037|PMID:21258407) RGD PMID:21258407 MGI:5050037 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxh1 forkhead box H1 involved_in IBA
ISO
PMID:21873635
(MGI:1321467|PMID:9858566), (MGI:1328655|PMID:10349617), (MGI:3055632|PMID:15363409)
RGD PMID:9858566 PMID:10349617 PMID:15363409 PMID:21873635 MGI:1321467 MGI:1328655 MGI:3055632, RGD:13792537 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049
JBrowse link
G Fshb follicle stimulating hormone subunit beta involved_in ISO (PMID:14557487) RGD PMID:14557487 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fut8 fucosyltransferase 8 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3608699 (MGI:3608245|PMID:16236725)
Ensembl
RGD
PMID:16236725 GO_REF:0000107 MGI:3608245 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO
IBA
(PMID:21750175)
(MGI:5545971|PMID:21750175)
PMID:21873635
RGD PMID:21750175 PMID:21873635 MGI:5545971, RGD:13792537 NCBI chr17:23,796,859...23,901,625
NCBI chr17:23,866,602...23,868,691
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Glg1 golgi glycoprotein 1 acts_upstream_of
involved_in
ISO
IEA
MGI:4829764 (MGI:4829577|PMID:20530870)
GO_REF:0000107
RGD
Ensembl
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:3487301 (MGI:3696537|PMID:17159989) RGD PMID:17159989 MGI:3696537 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase involved_in ISO
ISS
(PMID:15574495)
GO_REF:0000024
RGD
UniProt
PMID:15574495 GO_REF:0000024 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Itga8 integrin subunit alpha 8 acts_upstream_of ISO MGI:107430|MGI:2181699 (MGI:3714574|PMID:17537792) RGD PMID:17537792 MGI:3714574 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Itgb1 integrin subunit beta 1 NOT|involved_in ISO (PMID:24036928)
(MGI:5582864|PMID:24036928)
RGD PMID:24036928 MGI:5582864 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb5 integrin subunit beta 5 involved_in ISO (PMID:24036928)
(MGI:5582864|PMID:24036928)
RGD PMID:24036928 MGI:5582864 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO MGI:1338035|MGI:1926484 (MGI:3040752|PMID:12634787), (MGI:6376388|PMID:30952606) RGD PMID:12634787 PMID:30952606 MGI:3040752 MGI:6376388 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itgb8 integrin subunit beta 8 acts_upstream_of_or_within ISO MGI:96615 (MGI:6376388|PMID:30952606) RGD PMID:30952606 MGI:6376388 NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:9732876) RGD PMID:9732876 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lpxn leupaxin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
JBrowse link
G Lrrc32 leucine rich repeat containing 32 involved_in ISO (PMID:19750484) RGD PMID:19750484 NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 NAS RGD PMID:10028916 RGD:68276 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017|PR:P04202 (MGI:2389565|PMID:12379497), (MGI:72661|PMID:7730318) RGD PMID:7730318 PMID:12379497 MGI:2389565 MGI:72661 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 acts_upstream_of_or_within ISO MGI:2388061 (MGI:2386340|PMID:12208849) RGD PMID:12208849 MGI:2386340 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO MGI:2676654 (MGI:2674169|PMID:12941696) RGD PMID:12941696 MGI:2674169 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (MGI:3607216|PMID:16145668) RGD PMID:16145668 MGI:3607216 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mir143 microRNA 143 acts_upstream_of_or_within ISO MGI:2676830|MGI:5531026 (MGI:6208917|PMID:29925839) RGD PMID:29925839 MGI:6208917 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir145 microRNA 145 acts_upstream_of_or_within ISO MGI:2676828|MGI:5531026 (MGI:6208917|PMID:29925839) RGD PMID:29925839 MGI:6208917 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir183 microRNA 183 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
JBrowse link
G Mir212 microRNA 212 involved_in ISO (PMID:25217442) RGD PMID:25217442 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:20857419) RGD PMID:20857419 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
JBrowse link
G Mir30a microRNA 30a involved_in ISO (PMID:23960241) RGD PMID:23960241 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mstn myostatin acts_upstream_of_or_within ISO (MGI:2676508|PMID:12595574) RGD PMID:12595574 MGI:2676508 NCBI chr 9:48,453,982...48,458,809
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (MGI:6155267|PMID:29715368) RGD PMID:29715368 MGI:6155267 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nlk nemo like kinase involved_in ISO (PMID:15004007) RGD PMID:15004007 NCBI chr10:63,467,163...63,590,960
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Npnt nephronectin acts_upstream_of ISO MGI:3715213 (MGI:3714574|PMID:17537792) RGD PMID:17537792 MGI:3714574 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 PMID:21873635 GO_REF:0000024 MGI:6192878, RGD:13792537 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of ISO MGI:1891408 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277
JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of ISO MGI:1196423 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr18:57,831,647...57,881,287
Ensembl chr18:57,832,111...57,879,629
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 NOT|involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (MGI:3054278|PMID:15356634) RGD PMID:15356634 MGI:3054278 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISO (PMID:24036928) RGD PMID:24036928 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptprk protein tyrosine phosphatase, receptor type, K involved_in ISO (PMID:15899872) RGD PMID:15899872 NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605
JBrowse link
G Pxn paxillin involved_in ISO
IBA
(PMID:24036928)
(MGI:5582864|PMID:24036928)
PMID:21873635
RGD PMID:24036928 PMID:21873635 MGI:5582864, RGD:13792537 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23960241) RGD PMID:23960241 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:98725|MGI:98834 (MGI:3797158|PMID:18212064) RGD PMID:18212064 MGI:3797158 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Smad1 SMAD family member 1 involved_in ISO
IEA
IBA
(PMID:9389648)
GO_REF:0000002
PMID:21873635
GO_REF:0000107
RGD
InterPro
Ensembl
PMID:9389648 PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:13792537 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad2 SMAD family member 2 involved_in
acts_upstream_of_or_within
ISO
IBA
IMP
IEA
ISS
(PMID:18548003), (PMID:8752209), (PMID:8980228), (PMID:9389648), (PMID:9732876)
PMID:21873635
MGI:894293|MGI:98725|MGI:98834 (MGI:2153598|PMID:11557747), (MGI:3032478|PMID:14749725), (MGI:3797158|PMID:18212064)
PMID:22073128
GO_REF:0000002
GO_REF:0000024
RGD
InterPro
UniProt
PMID:8752209 PMID:8980228 PMID:9389648 PMID:9732876 PMID:11557747 More... GO_REF:0000002 GO_REF:0000024 MGI:2153598 MGI:3032478 MGI:3797158, RGD:13792537, RGD:8554355 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 involved_in
acts_upstream_of_or_within
IMP
IEA
IBA
ISO
GO_REF:0000002
PMID:21873635
(PMID:18548003), (PMID:21947082), (PMID:28467929), (PMID:9732876)
(MGI:3505646|PMID:15239668), (MGI:3690196|PMID:16619037), (MGI:5300220|PMID:21937600)
PMID:22073128
TGFbeta-1 dependent, in pancreatic stellate cells
InterPro
RGD
PMID:9732876 PMID:15239668 PMID:16619037 PMID:18548003 PMID:21937600 More... GO_REF:0000002 MGI:3505646 MGI:3690196 MGI:5300220, RGD:1625706, RGD:13792537, RGD:8554355, RGD:2300404 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:108051|MGI:98725|MGI:98834 (MGI:3797158|PMID:18212064)
(MGI:3769957|PMID:16330325)
GO_REF:0000002
(PMID:25514493), (PMID:9389648), (PMID:9732876)
Ensembl
RGD
InterPro
PMID:9389648 PMID:9732876 PMID:16330325 PMID:18212064 PMID:25514493 More... GO_REF:0000002 GO_REF:0000107 MGI:3769957 MGI:3797158, RGD:13792537 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad5 SMAD family member 5 acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:1935017|PMID:11376112)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:11376112 PMID:21873635 GO_REF:0000002 MGI:1935017, RGD:13792537 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Smad6 SMAD family member 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000002
PMID:21873635
(MGI:2153598|PMID:11557747)
Ensembl
InterPro
RGD
PMID:11557747 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:2153598, RGD:13792537 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smad9 SMAD family member 9 involved_in IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6453080|PMID:31314592) RGD PMID:31314592 MGI:6453080 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:24036928) RGD PMID:24036928 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO UniProtKB:P01137 (PMID:28467929) RGD PMID:28467929 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 acts_upstream_of_or_within ISO MGI:2667182 (MGI:2447107|PMID:12464436) RGD PMID:12464436 MGI:2447107 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEP
GO_REF:0000024
(PMID:1333888)
PMID:21873635
(PMID:11157754), (PMID:28467929), (PMID:31023188), (PMID:9389648)
(MGI:2386340|PMID:12208849), (MGI:5543310|PMID:23868260)
UniProt
RGD
PMID:1333888 PMID:9389648 PMID:11157754 PMID:12208849 PMID:23868260 More... GO_REF:0000024 MGI:2386340 MGI:5543310, RGD:13792537, RGD:127229954 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:1333888)
(PMID:11157754), (PMID:18358889)
AgBase
RGD
PMID:1333888 PMID:11157754 PMID:18358889 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:1333888)
PMID:21873635
(PMID:11157754), (PMID:18718461)
AgBase
RGD
PMID:1333888 PMID:11157754 PMID:18718461 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
ISS
MGI:2386570|MGI:2388050 (MGI:1933434|PMID:11285230), (MGI:2679137|PMID:14580334), (MGI:3575204|PMID:15820682), (MGI:3703113|PMID:17078885), (MGI:5298182|PMID:21832243)
UniProtKB:P10600 (MGI:3820811|PMID:18718461)
(PMID:11157754), (PMID:1333888), (PMID:9389648)
PMID:21873635
GO_REF:0000024
RGD
AgBase
PMID:1333888 PMID:9389648 PMID:11157754 PMID:11285230 PMID:14580334 More... GO_REF:0000024 MGI:1933434 MGI:2679137 MGI:3575204 MGI:3703113 MGI:3820811 MGI:5298182, RGD:737663, RGD:13792537, RGD:2302517, RGD:2302021 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in
acts_upstream_of_or_within
TAS
ISO
IBA
IMP
(PMID:11157754)
MGI:2384513 (MGI:4949016|PMID:21420963)
(PMID:1333888), (PMID:18453574)
PMID:21873635
RGD PMID:1333888 PMID:11157754 PMID:18453574 PMID:21420963 PMID:12183510 More... MGI:4949016, RGD:727411, RGD:13792537, RGD:2302517 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of
involved_in
TAS
ISO
IBA
(MGI:5617089|PMID:25382630)
UniProtKB:P27090 (MGI:2663364|PMID:12773577), (MGI:3699491|PMID:17295310), (MGI:3807767|PMID:11546783)
PMID:21873635
(PMID:11157754), (PMID:12958365)
RGD PMID:11157754 PMID:11546783 PMID:12773577 PMID:12958365 PMID:17295310 More... MGI:2663364 MGI:3699491 MGI:3807767 MGI:5617089, RGD:729942, RGD:13792537 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:2,600,934...2,604,222 JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO MGI:4001992 (MGI:6094918|PMID:28811219) RGD PMID:28811219 MGI:6094918 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:108051|MGI:894293|MGI:98725 (MGI:3797158|PMID:18212064) RGD PMID:18212064 MGI:3797158 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:105,533,116...105,567,525
Ensembl chr 9:105,533,136...105,567,479
JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO
ISS
IEA
(PMID:21947082), (PMID:22344298)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:21947082 PMID:22344298 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:19135894) RGD PMID:19135894 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711
JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 acts_upstream_of_or_within ISO (MGI:2676508|PMID:12595574) RGD PMID:12595574 MGI:2676508 NCBI chr10:79,185,563...79,192,719
Ensembl chr10:79,186,647...79,191,657
JBrowse link
G Zfyve9 zinc finger FYVE-type containing 9 involved_in ISO
IBA
(PMID:9865696)
PMID:21873635
RGD PMID:9865696 PMID:21873635 RGD:13792537 NCBI chr 5:123,370,677...123,529,699
Ensembl chr 5:123,370,677...123,529,699
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 NOT|involved_in ISO (PMID:16777850) RGD PMID:16777850 NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936
JBrowse link
G Zyx zyxin involved_in IBA
ISO
PMID:21873635
(MGI:5582864|PMID:24036928)
(PMID:24036928)
RGD PMID:24036928 PMID:21873635 MGI:5582864, RGD:13792537 NCBI chr 4:71,236,767...71,246,553
Ensembl chr 4:71,237,451...71,246,553
JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:21170088) RGD PMID:21170088 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adamtsl2 ADAMTS-like 2 involved_in
acts_upstream_of_or_within
ISO (PMID:18677313)
(MGI:5638958|PMID:25762570)
RGD PMID:18677313 PMID:25762570 MGI:5638958 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554
JBrowse link
G Aspn asporin involved_in ISO (PMID:17827158)
(MGI:3762064|PMID:17827158)
RGD PMID:17827158 MGI:3762064 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor involved_in ISO
IEA
(PMID:14660579), (PMID:19328798)
GO_REF:0000002
RGD
InterPro
PMID:14660579 PMID:19328798 GO_REF:0000002 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bcl9l BCL9 like involved_in ISO
IBA
(PMID:19328798)
PMID:21873635
RGD PMID:19328798 PMID:21873635 RGD:13792537 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
UniProtKB:P01137 (PMID:28467929)
GO_REF:0000107
RGD
Ensembl
PMID:28467929 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Brms1l BRMS1 like transcriptional repressor involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 6:73,266,673...73,300,631
Ensembl chr 6:73,266,691...73,300,631
JBrowse link
G Cav1 caveolin 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 GO_REF:0000024 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav2 caveolin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98728 (MGI:5298182|PMID:21832243)
Ensembl
RGD
PMID:21832243 GO_REF:0000107 MGI:5298182 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cd109 CD109 molecule involved_in ISO (PMID:16754747) RGD PMID:16754747 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (MGI:3767479|PMID:16079159) RGD PMID:16079159 MGI:3767479 NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111
JBrowse link
G Cidea cell death-inducing DFFA-like effector a involved_in ISO (MGI:3768618|PMID:17080483) RGD PMID:17080483 MGI:3768618 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cilp cartilage intermediate layer protein involved_in ISO (PMID:29167509) RGD PMID:29167509 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO MGI:97359 (MGI:3055566|PMID:14721776) RGD PMID:14721776 MGI:3055566 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:25100282 RGD:9685289 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,217...83,542,262 JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698
JBrowse link
G Fam89b family with sequence similarity 89, member B involved_in IBA
ISO
PMID:21873635
(MGI:5486566|PMID:12646588)
RGD PMID:12646588 PMID:21873635 MGI:5486566, RGD:13792537 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 acts_upstream_of_or_within ISO MGI:98658 (MGI:3771280|PMID:17991893) RGD PMID:17991893 MGI:3771280 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htra1 HtrA serine peptidase 1 acts_upstream_of_or_within ISO (MGI:3034116|PMID:14973287) RGD PMID:14973287 MGI:3034116 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htra3 HtrA serine peptidase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3046453|PMID:15206957)
UniProt
RGD
PMID:15206957 GO_REF:0000024 MGI:3046453 NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315
JBrowse link
G Il17rd interleukin 17 receptor D involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 involved_in ISO
IBA
(PMID:24627487)
(MGI:5583005|PMID:24627487)
PMID:21873635
RGD PMID:24627487 PMID:21873635 MGI:5583005, RGD:13792537 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lemd3 LEM domain containing 3 involved_in ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:56,415,053...56,499,047
Ensembl chr 7:56,305,448...56,502,474
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO UniProtKB:P01137 (MGI:6434720|PMID:31023188) RGD PMID:31023188 MGI:6434720 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Mecom MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) RGD PMID:15897867 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir18a microRNA 18a involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:21145484) RGD PMID:21145484 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:26687115) RGD PMID:26687115 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:26687115) RGD PMID:26687115 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Mir342 microRNA 342 involved_in ISO (PMID:26857067) RGD PMID:26857067 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mirlet7f-1 microRNA let7f-1 involved_in ISO (PMID:28345812) RGD PMID:28345812 NCBI chr17:16,114,130...16,114,226
Ensembl chr17:16,114,130...16,114,226
JBrowse link
G Mirlet7f2 microRNA let-7f-2 involved_in ISO (PMID:28345812) RGD PMID:28345812 NCBI chr  X:20,980,632...20,980,714
Ensembl chr  X:20,980,632...20,980,714
JBrowse link
G Mirlet7g microRNA let-7g involved_in ISO (PMID:24291274) RGD PMID:24291274 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in ISO
IEA
(PMID:19293183)
GO_REF:0000107
RGD
Ensembl
PMID:19293183 GO_REF:0000107 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
JBrowse link
G Onecut1 one cut homeobox 1 acts_upstream_of_or_within ISO MGI:1891408 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277
JBrowse link
G Onecut2 one cut homeobox 2 acts_upstream_of_or_within ISO MGI:1196423 (MGI:3588024|PMID:16103213) RGD PMID:16103213 MGI:3588024 NCBI chr18:57,831,647...57,881,287
Ensembl chr18:57,832,111...57,879,629
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 involved_in ISO (PMID:23687415) RGD PMID:23687415 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:17327236) RGD PMID:17327236 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Peg10 paternally expressed 10 involved_in ISO (PMID:15611116) RGD PMID:15611116 NCBI chr 4:32,842,394...32,855,641
Ensembl chr 4:32,848,493...32,852,621
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:19122240) RGD PMID:19122240 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 involved_in ISO
IBA
(PMID:20129061), (PMID:24627487)
(MGI:5582164|PMID:20129061)
PMID:21873635
RGD PMID:20129061 PMID:24627487 PMID:21873635 MGI:5582164, RGD:13792537 NCBI chr 3:162,011,884...162,060,137
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO (PMID:31611175) RGD PMID:31611175 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in
acts_upstream_of_or_within
ISO (PMID:31023188)
UniProtKB:P01137|UniProtKB:P12643 (PMID:28467929)
RGD PMID:28467929 PMID:31023188 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A involved_in ISO
IEA
(PMID:16751101)
GO_REF:0000107
RGD
Ensembl
PMID:16751101 GO_REF:0000107 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Prdm16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within
ISO (PMID:14656887)
MGI:3576024 (MGI:4430027|PMID:20007998)
(PMID:19049980)
RGD PMID:14656887 PMID:19049980 PMID:20007998 MGI:4430027 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Rasl11b RAS-like family 11 member B acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) RGD PMID:15239668 MGI:3505646 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306300|PMID:17098745) RGD PMID:17098745 MGI:5306300 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Ski Ski proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P01137 (PMID:15312649)
(PMID:17054724), (PMID:17469184), (PMID:19049980)
MGI:1201674 (MGI:5300220|PMID:21937600)
RGD PMID:15312649 PMID:17054724 PMID:17469184 PMID:19049980 PMID:21937600 More... MGI:5300220, RGD:13792537 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Skil SKI-like proto-oncogene involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3530729|PMID:15677329)
(PMID:17469184), (PMID:19383336)
RGD PMID:15677329 PMID:17469184 PMID:19383336 PMID:21873635 MGI:3530729, RGD:13792537 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within
ISO (PMID:16200078)
(MGI:5300220|PMID:21937600)
RGD PMID:16200078 PMID:21937600 MGI:5300220 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171), (PMID:26376865) RGD PMID:16550171 PMID:26376865 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:19047146), (PMID:9256479) RGD PMID:9256479 PMID:19047146 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
JBrowse link
G Smad7 SMAD family member 7 involved_in ISO
IEA
(PMID:12151385), (PMID:17438144), (PMID:18762808), (PMID:9256479)
GO_REF:0000107
RGD
Ensembl
PMID:9256479 PMID:12151385 PMID:17438144 PMID:18762808 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:11278251), (PMID:12151385) RGD PMID:11278251 PMID:12151385 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in ISO (PMID:19255252) RGD PMID:19255252 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
JBrowse link
G Snx1 sorting nexin 1 acts_upstream_of_or_within ISO (MGI:3505646|PMID:15239668) RGD PMID:15239668 MGI:3505646 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360
JBrowse link
G Snx25 sorting nexin 25 involved_in ISO (PMID:21266196)
(MGI:5545984|PMID:21266196)
RGD PMID:21266196 MGI:5545984 NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440
JBrowse link
G Snx6 sorting nexin 6 involved_in ISO (PMID:11279102) RGD PMID:11279102 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414689|PMID:25576668)
UniProt
RGD
PMID:25576668 GO_REF:0000024 MGI:6414689 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Strap serine/threonine kinase receptor associated protein involved_in
acts_upstream_of_or_within
ISO (PMID:23687415)
(MGI:1321347|PMID:9856985)
RGD PMID:9856985 PMID:23687415 MGI:1321347 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:24613385) RGD PMID:24613385 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Suds3 SDS3 homolog, SIN3A corepressor complex component involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr12:39,477,181...39,499,633
Ensembl chr12:39,477,568...39,499,628
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 acts_upstream_of_or_within ISO MGI:95835 (MGI:3771280|PMID:17991893) RGD PMID:17991893 MGI:3771280 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:12071374 RGD:730235 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IDA RGD PMID:10746731 RGD:1579946 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:3528807|PMID:15657445) RGD PMID:15657445 MGI:3528807 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Vasn vasorin involved_in IBA
ISO
PMID:21873635
(PMID:15247411), (PMID:21170088)
RGD PMID:15247411 PMID:21170088 PMID:21873635 RGD:13792537 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26039994)
UniProt
Ensembl
RGD
PMID:26039994 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in ISO
IBA
(PMID:21054789)
PMID:21873635
RGD PMID:21054789 PMID:21873635 RGD:13792537 NCBI chr10:14,896,442...14,898,770
Ensembl chr10:14,896,378...14,899,863
JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in ISO
IBA
(PMID:21054789)
PMID:21873635
RGD PMID:21054789 PMID:21873635 RGD:13792537 NCBI chr10:79,185,563...79,192,719
Ensembl chr10:79,186,647...79,191,657
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25514493)
UniProt
Ensembl
RGD
PMID:25514493 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539
JBrowse link
G Zfp451 zinc finger protein 451 involved_in ISO (PMID:24324267) RGD PMID:24324267 NCBI chr 9:35,985,441...36,040,991
Ensembl chr 9:35,985,443...36,040,652
JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:3829110|PMID:18625725) RGD PMID:18625725 MGI:3829110 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO MGI:1934919 (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C involved_in ISO (PMID:16943770) RGD PMID:16943770 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B involved_in ISO (PMID:16943770) RGD PMID:16943770 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3690196|PMID:16619037)
UniProt
RGD
PMID:16619037 GO_REF:0000024 MGI:3690196 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Crebbp CREB binding protein involved_in IEA
ISO
GO_REF:0000107
(PMID:25514493)
Ensembl
RGD
PMID:25514493 GO_REF:0000107 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:11387212)
Ensembl
RGD
PMID:11387212 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:25514493) RGD PMID:25514493 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Fermt1 FERM domain containing kindlin 1 involved_in ISO (MGI:5571208|PMID:24681597) RGD PMID:24681597 MGI:5571208 NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555
JBrowse link
G Flcn folliculin involved_in
acts_upstream_of_or_within
ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
MGI:4348628 (MGI:5050037|PMID:21258407)
(PMID:20573232)
UniProt
RGD
PMID:20573232 PMID:21258407 PMID:21873635 GO_REF:0000024 MGI:5050037, RGD:13792537 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) IMP RGD PMID:15194465 RGD:1582619 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO (MGI:3807767|PMID:11546783) RGD PMID:11546783 MGI:3807767 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:26880260 RGD:13504840 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14678985) RGD PMID:14678985 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
ISS
(PMID:24613385)
GO_REF:0000024
RGD
UniProt
PMID:24613385 GO_REF:0000024 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Ing2 inhibitor of growth family, member 2 involved_in ISO (PMID:18334480) RGD PMID:18334480 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
JBrowse link
G Itga8 integrin subunit alpha 8 acts_upstream_of_or_within ISO MGI:107430|MGI:2181699 (MGI:3714574|PMID:17537792) RGD PMID:17537792 MGI:3714574 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 acts_upstream_of_or_within
involved_in
ISO MGI:98725 (MGI:5543310|PMID:23868260)
(PMID:23868260), (PMID:32887674)
RGD PMID:23868260 PMID:32887674 MGI:5543310 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813
JBrowse link
G Men1 menin 1 involved_in ISO (PMID:11274402) RGD PMID:11274402 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mir21 microRNA 21 acts_upstream_of ISO (PMID:31611175) RGD PMID:31611175 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir30b microRNA 30b involved_in ISO (PMID:28977001) RGD PMID:28977001 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675
JBrowse link
G Myocd myocardin involved_in IEA
ISO
GO_REF:0000107
(MGI:3696631|PMID:16224064)
Ensembl
RGD
PMID:16224064 GO_REF:0000107 MGI:3696631 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Npnt nephronectin acts_upstream_of_or_within ISO MGI:3715213 (MGI:3714574|PMID:17537792) RGD PMID:17537792 MGI:3714574 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
JBrowse link
G RGD1311739 similar to RIKEN cDNA 1700037H04 involved_in ISO (PMID:32024300) RGD PMID:32024300 NCBI chr 3:118,364,730...118,378,881
Ensembl chr 3:118,362,363...118,378,838
JBrowse link
G Rnf111 ring finger protein 111 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3628833|PMID:16601693)
RGD PMID:16601693 PMID:21873635 MGI:3628833, RGD:13792537 NCBI chr 8:71,103,967...71,180,172
Ensembl chr 8:71,103,973...71,145,070
JBrowse link
G Sdcbp syndecan binding protein involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:25893292)
UniProt
RGD
PMID:25893292 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:26376865) RGD PMID:26376865 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:19328798)
Ensembl
RGD
PMID:19328798 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:11278756) RGD PMID:11278756 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO (PMID:18311138)
(MGI:3788958|PMID:18311138)
RGD PMID:18311138 MGI:3788958 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 acts_upstream_of_or_within IMP
ISO
(MGI:5617089|PMID:25382630) RGD PMID:25382630 PMID:8106553 MGI:5617089, RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18555217)
(MGI:1270011|PMID:9657149)
RGD PMID:9657149 PMID:18555217 MGI:1270011 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO (PMID:30592286) RGD PMID:30592286 NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9, transcription coactivator NOT|involved_in ISO (PMID:19328798) RGD PMID:19328798 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435
JBrowse link
G Cav3 caveolin 3 acts_upstream_of_or_within ISO (MGI:4946902|PMID:21182936) RGD PMID:21182936 MGI:4946902 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 acts_upstream_of_or_within ISO (MGI:1335654|PMID:10208746) RGD PMID:10208746 MGI:1335654 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,217...83,542,262 JBrowse link
G Eng endoglin involved_in IDA
ISO
IBA
(PMID:15702480)
PMID:21873635
RGD PMID:15702480 PMID:17376778 PMID:21873635 RGD:2313627, RGD:13792537 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:5644149|PMID:21649587) RGD PMID:21649587 MGI:5644149 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Gdf2 growth differentiation factor 2 NOT|involved_in ISO (MGI:4830635|PMID:20406889) RGD PMID:20406889 MGI:4830635 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Il17f interleukin 17F involved_in ISO
IEA
(PMID:11591732)
GO_REF:0000107
RGD
Ensembl
PMID:11591732 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482
Ensembl chr 9:23,190,100...23,201,482
JBrowse link
G Itga3 integrin subunit alpha 3 involved_in ISO (PMID:24621570) RGD PMID:24621570 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO (MGI:4939579|PMID:21145499) RGD PMID:21145499 MGI:4939579 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640
JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO (MGI:4939579|PMID:21145499) RGD PMID:21145499 MGI:4939579 NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220
JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO MGI:3610732 (MGI:5634219|PMID:25715398) RGD PMID:25715398 MGI:5634219 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Nrep neuronal regeneration related protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3034115|PMID:14985127)
RGD PMID:14985127 PMID:21873635 MGI:3034115, RGD:13792537 NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Pals1 protein associated with LIN7 1, MAGUK p55 family member involved_in ISS
ISO
GO_REF:0000024
(MGI:4939579|PMID:21145499)
UniProt
RGD
PMID:21145499 GO_REF:0000024 MGI:4939579 NCBI chr 6:97,548,133...97,654,163
Ensembl chr 6:97,548,630...97,653,305
JBrowse link
G Smad2 SMAD family member 2 involved_in ISO (PMID:14555988) RGD PMID:14555988 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 involved_in
acts_upstream_of_or_within
ISO (PMID:8774881)
(MGI:2153314|PMID:11711431)
RGD PMID:8774881 PMID:11711431 MGI:2153314 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 involved_in ISO (PMID:8774881) RGD PMID:8774881 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad7 SMAD family member 7 IDA RGD PMID:11959632 RGD:625758 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISO (PMID:20624318) RGD PMID:20624318 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:15334054)
GO_REF:0000024
RGD
UniProt
PMID:15334054 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:2,600,934...2,604,222 JBrowse link
G Trim33 tripartite motif-containing 33 involved_in ISO (PMID:19135894) RGD PMID:19135894 NCBI chr 2:190,812,329...190,892,663
Ensembl chr 2:190,807,243...190,888,814
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1201674 (MGI:3641341|PMID:16824956)
Ensembl
RGD
PMID:16824956 GO_REF:0000107 MGI:3641341 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zfp703 zinc finger protein 703 involved_in ISO (PMID:21337521)
(MGI:4940410|PMID:21317240)
RGD PMID:21317240 PMID:21337521 MGI:4940410 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO
ISS
(PMID:2022183), (PMID:8617200)
GO_REF:0000024
RGD
UniProt
PMID:2022183 PMID:8617200 GO_REF:0000024 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C IDA TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 involved_in ISO (PMID:14612439) RGD PMID:14612439 NCBI chr 1:83,538,217...83,542,262 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 IMP RGD PMID:8106553 RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
transforming growth factor beta receptor signaling pathway involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:67103|PMID:8009224) RGD PMID:8009224 MGI:67103 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
transforming growth factor beta receptor signaling pathway involved in primitive streak formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    cellular process 18297
      signal transduction 7129
        cell surface receptor signaling pathway 2867
          enzyme-linked receptor protein signaling pathway 1043
            transmembrane receptor protein serine/threonine kinase signaling pathway 423
              transforming growth factor beta receptor signaling pathway 212
                negative regulation of transforming growth factor beta receptor signaling pathway + 91
                positive regulation of transforming growth factor beta receptor signaling pathway 34
                regulation of transforming growth factor beta receptor signaling pathway + 141
                transforming growth factor beta receptor complex assembly 3
                transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry + 0
                transforming growth factor beta receptor signaling pathway involved in heart development + 1
                transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation 0
                transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment + 0
                transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
                transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth 0
                transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification 0
Path 2
Term Annotations click to browse term
  biological_process 19903
    biological regulation 13542
      regulation of biological process 13094
        regulation of cellular process 12367
          signal transduction 7129
            cell surface receptor signaling pathway 2867
              enzyme-linked receptor protein signaling pathway 1043
                transmembrane receptor protein serine/threonine kinase signaling pathway 423
                  transforming growth factor beta receptor signaling pathway 212
                    negative regulation of transforming growth factor beta receptor signaling pathway + 91
                    positive regulation of transforming growth factor beta receptor signaling pathway 34
                    regulation of transforming growth factor beta receptor signaling pathway + 141
                    transforming growth factor beta receptor complex assembly 3
                    transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry + 0
                    transforming growth factor beta receptor signaling pathway involved in heart development + 1
                    transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation 0
                    transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment + 0
                    transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 1
                    transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth 0
                    transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification 0
paths to the root