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ONTOLOGY REPORT - ANNOTATIONS

Term:cell surface receptor protein serine/threonine kinase signaling pathway
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Accession:GO:0007178 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: transmembrane receptor protein serine/threonine kinase signalling pathway
 broad_synonym: transmembrane receptor protein serine/threonine kinase signaling pathway


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cell surface receptor protein serine/threonine kinase signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:73273|PMID:8388127) InterPro
GOC		 PMID:8388127 GO_REF:0000002 MGI:73273 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR1B activin A receptor type 1B involved_in IEA InterPro GO_REF:0000002 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G ACVR1C activin A receptor type 1C involved_in IEA InterPro GO_REF:0000002 NCBI chr36:3,534,231...3,583,310
Ensembl chr36:3,541,248...3,613,384 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in IEA InterPro GO_REF:0000002 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in IEA InterPro GO_REF:0000002 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G AKAP3 A-kinase anchoring protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10319321) Ensembl
MGI		 PMID:10319321 GO_REF:0000107 NCBI chr27:40,217,313...40,255,934
Ensembl chr27:40,218,035...40,250,954 		JBrowse link
G AKAP4 A-kinase anchoring protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9852104) Ensembl
MGI		 PMID:9852104 GO_REF:0000107 NCBI chr  X:42,935,831...42,946,248
Ensembl chr  X:42,935,815...42,946,149 		JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18363966) InterPro
MGI
Ensembl		 PMID:18363966 GO_REF:0000002 GO_REF:0000107 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10465784) TreeGrafter
MGI		 PMID:10465784 GO_REF:0000118 NCBI chr20:49,848,848...49,867,075
Ensembl chr20:49,848,912...49,867,066 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18363966) Ensembl
MGI		 PMID:18363966 GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G LOC102154767 lymphocyte antigen 6G6e-like involved_in IEA GOC GO_REF:0000108 NCBI chr12:1,189,910...1,196,762 JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18363966) Ensembl
MGI		 PMID:18363966 GO_REF:0000107 NCBI chr12:5,145,647...5,221,558
Ensembl chr12:5,146,037...5,220,603 		JBrowse link
G PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12823230) Ensembl
MGI		 PMID:12823230 GO_REF:0000107 NCBI chr34:26,770,442...27,060,892
Ensembl chr34:26,770,569...27,057,910 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO (PMID:18363966) MGI PMID:18363966 NCBI chr13:15,017,180...15,273,177
Ensembl chr13:15,022,652...15,273,666 		JBrowse link
activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR1B activin A receptor type 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16115198) Ensembl
TreeGrafter
MGI
RGD		 PMID:16115198 PMID:17040568 GO_REF:0000107 GO_REF:0000118 RGD:2315948 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G ACVR1C activin A receptor type 1C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr36:3,534,231...3,583,310
Ensembl chr36:3,541,248...3,613,384 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in IEA GOC GO_REF:0000108 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G BMP10 bone morphogenetic protein 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:67,717,047...67,724,778
Ensembl chr10:67,717,980...67,724,739 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA GOC GO_REF:0000108 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G FGF9 fibroblast growth factor 9 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23034635) Ensembl
MGI		 PMID:23034635 GO_REF:0000107 NCBI chr25:16,630,321...16,665,935
Ensembl chr25:16,632,812...16,663,550 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in ISO (PMID:28257634) GO_Central PMID:28257634 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373 		JBrowse link
G GDF2 growth differentiation factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (PMID:16049014) BHF-UCL PMID:16049014 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G GDF7 growth differentiation factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,627,739...15,636,513 JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in ISO (PMID:18326817) BHF-UCL PMID:18326817 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G INHBA inhibin subunit beta A involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794 		JBrowse link
G INHBB inhibin subunit beta B involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:29,765,697...29,768,485
Ensembl chr19:29,767,682...29,768,077 		JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
anti-Mullerian hormone receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMH anti-Mullerian hormone involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,785,960...56,788,815 JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 involved_in ISO (PMID:7493017)
(PMID:10854429)		 UniProt PMID:7493017 PMID:10854429 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533 		JBrowse link
BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22729085) Ensembl
MGI		 PMID:22729085 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:19366699)
(PMID:17472960)
(MGI:5751611|PMID:26774823)
(PMID:18436533)		 BHF-UCL
MGI
UniProt		 PMID:17472960 PMID:18436533 PMID:19366699 PMID:26774823 MGI:5751611 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:18436533)
(PMID:19903896)		 BHF-UCL PMID:18436533 PMID:19903896 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22783020) Ensembl
MGI		 PMID:22783020 GO_REF:0000107 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533 		JBrowse link
G ATF2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G BMP10 bone morphogenetic protein 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16049014) MGI
TreeGrafter
Ensembl		 PMID:16049014 GO_REF:0000107 GO_REF:0000118 NCBI chr10:67,717,047...67,724,778
Ensembl chr10:67,717,980...67,724,739 		JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14623234), (PMID:19208758), (PMID:19852960), (PMID:20065295), (PMID:25100727)
(PMID:15975920)
(PMID:17472960)		 RGD
MGI
TreeGrafter
Ensembl		 PMID:12398941 PMID:14623234 PMID:15975920 PMID:17472960 PMID:19208758 More... GO_REF:0000107 GO_REF:0000118 RGD:631753 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17472960)
(PMID:15975920)
(PMID:14623234), (PMID:17472960)		 MGI
TreeGrafter
Ensembl		 PMID:14623234 PMID:15975920 PMID:17472960 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14623234), (PMID:19852960) Ensembl
MGI
TreeGrafter		 PMID:14623234 PMID:19852960 GO_REF:0000107 GO_REF:0000118 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14623234) Ensembl
MGI
TreeGrafter		 PMID:14623234 GO_REF:0000107 GO_REF:0000118 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in ISO (PMID:20807528) MGI PMID:20807528 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17699604)
(PMID:16049014)
(PMID:16604073)
(PMID:16943278)
(PMID:9268344)		 Ensembl
MGI
TreeGrafter		 PMID:9268344 PMID:16049014 PMID:16604073 PMID:16943278 PMID:17699604 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11376112)
(PMID:16604073)
(PMID:16049014)		 Ensembl
MGI
TreeGrafter		 PMID:11376112 PMID:16049014 PMID:16604073 GO_REF:0000107 GO_REF:0000118 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17472960) Ensembl
MGI
TreeGrafter		 PMID:17472960 GO_REF:0000107 GO_REF:0000118 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G CHRD chordin involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,255,770...17,264,776
Ensembl chr34:17,255,562...17,271,713 		JBrowse link
G CHRDL1 chordin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:83,816,131...83,936,497
Ensembl chr  X:83,817,880...83,936,949 		JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21350216) Ensembl
MGI		 PMID:21350216 GO_REF:0000107 NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625 		JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:12,300,706...12,307,931
Ensembl chr 9:12,300,708...12,307,663 		JBrowse link
G DLX3 distal-less homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,018,101...26,022,964
Ensembl chr 9:26,017,689...26,022,736 		JBrowse link
G DLX5 distal-less homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:22,080,351...22,085,188
Ensembl chr14:22,080,699...22,084,867 		JBrowse link
G DSG4 desmoglein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18692037) Ensembl
MGI		 PMID:18692037 GO_REF:0000107 NCBI chr 7:58,101,294...58,135,376 JBrowse link
G ECSIT ECSIT signaling integrator acts_upstream_of_or_within ISO (PMID:14633973) MGI PMID:14633973 NCBI chr20:49,848,848...49,867,075
Ensembl chr20:49,848,912...49,867,066 		JBrowse link
G EGR1 early growth response 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8769660) Ensembl
MGI		 PMID:8769660 GO_REF:0000107 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:23,931,360...23,971,516
Ensembl chr 1:23,960,723...23,969,405 		JBrowse link
G ETV2 ETS variant transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18462699) Ensembl
MGI		 PMID:18462699 GO_REF:0000107 NCBI chr 1:116,971,238...116,974,831
Ensembl chr 1:116,971,365...116,985,796 		JBrowse link
G EXT1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21148566), (PMID:22556407), (PMID:23458899), (PMID:28445472)
(PMID:22556407)		 Ensembl
MGI		 PMID:21148566 PMID:22556407 PMID:23458899 PMID:28445472 GO_REF:0000107 NCBI chr13:17,172,497...17,457,084
Ensembl chr13:17,172,705...17,456,469 		JBrowse link
G FAM83B family with sequence similarity 83 member B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:22,256,452...22,341,919
Ensembl chr12:22,257,110...22,338,231 		JBrowse link
G FAM83D family with sequence similarity 83 member D involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:27,302,442...27,323,780
Ensembl chr24:27,302,469...27,323,350 		JBrowse link
G FAM83E family with sequence similarity 83 member E involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:107,694,963...107,705,303
Ensembl chr 1:107,696,416...107,705,310 		JBrowse link
G FAM83F family with sequence similarity 83 member F involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:25,106,663...25,140,989
Ensembl chr10:25,108,003...25,140,989 		JBrowse link
G FAM83G family with sequence similarity 83 member G involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:41,054,805...41,085,156
Ensembl chr 5:41,055,311...41,084,739 		JBrowse link
G FAM83H family with sequence similarity 83 member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:37,324,090...37,332,421
Ensembl chr13:37,325,548...37,336,834 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FST follistatin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15525533) Ensembl
MGI		 PMID:15525533 GO_REF:0000107 NCBI chr 4:61,779,252...61,785,666
Ensembl chr 4:61,779,259...61,783,260 		JBrowse link
G GDF2 growth differentiation factor 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16049014) TreeGrafter
MGI		 PMID:16049014 GO_REF:0000118 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G GDF7 growth differentiation factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16049014) Ensembl
MGI
TreeGrafter		 PMID:16049014 GO_REF:0000107 GO_REF:0000118 NCBI chr17:15,627,739...15,636,513 JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HIVEP1 HIVEP zinc finger 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:11,551,270...11,705,629
Ensembl chr35:11,555,221...11,705,002 		JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16604073)
(PMID:19751239)
(PMID:16604073), (PMID:24409331)		 Ensembl
MGI
TreeGrafter		 PMID:16604073 PMID:19751239 PMID:24409331 GO_REF:0000107 GO_REF:0000118 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G ID1 inhibitor of DNA binding 1 acts_upstream_of_or_within ISO (PMID:15820682) MGI PMID:15820682 NCBI chr24:21,094,339...21,096,276
Ensembl chr24:21,094,755...21,096,276 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9769173) Ensembl
MGI		 PMID:9769173 GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:19664780) BHF-UCL PMID:19664780 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MEGF8 multiple EGF like domains 8 involved_in ISO (MGI:5551355|PMID:24052814) UniProt PMID:24052814 MGI:5551355 NCBI chr 1:112,020,344...112,063,120
Ensembl chr 1:112,021,960...112,024,773 		JBrowse link
G MIR122 microRNA mir-122 acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr 1:17,593,858...17,593,915
Ensembl chr 1:17,593,837...17,593,929 		JBrowse link
G MIR125A microRNA mir-125a acts_upstream_of_or_within ISO (PMID:22751012) MGI PMID:22751012 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
G MIR147 microRNA mir-147 acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr30:11,800,621...11,800,706
Ensembl chr30:11,800,621...11,800,706 		JBrowse link
G MIR16-1 microRNA mir-16-1 acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr22:1,847,020...1,847,084
Ensembl chr22:1,847,007...1,847,093 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR23A microRNA mir-23a acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr20:48,620,335...48,620,386
Ensembl chr20:48,620,323...48,620,397 		JBrowse link
G MIRLET7D microRNA let-7d acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr 1:97,902,012...97,902,136
Ensembl chr 1:97,902,012...97,902,136 		JBrowse link
G MIRLET7F microRNA let-7f acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr 1:97,903,931...97,904,008
Ensembl chr 1:97,903,919...97,904,028 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17601530), (PMID:18667074)
(PMID:18590716)
(PMID:18667074)		 Ensembl
MGI		 PMID:17601530 PMID:18590716 PMID:18667074 GO_REF:0000107 NCBI chr 3:70,232,790...70,236,295
Ensembl chr 3:70,232,052...70,236,447 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:18590716)
(PMID:18667074)
(PMID:17601530), (PMID:18667074)		 MGI PMID:17601530 PMID:18590716 PMID:18667074 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of ISO (PMID:16801560) MGI PMID:16801560 NCBI chr27:37,262,558...37,266,449 JBrowse link
G NFIA nuclear factor I A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:48,489,521...49,064,867
Ensembl chr 5:48,496,773...49,064,848 		JBrowse link
G NOG noggin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18462699) Ensembl
MGI		 PMID:18462699 GO_REF:0000107 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23676271) Ensembl
MGI		 PMID:23676271 GO_REF:0000107 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857 		JBrowse link
G PDCD4 programmed cell death 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:22,198,274...22,227,184
Ensembl chr28:22,198,322...22,226,717 		JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:18382765) BHF-UCL PMID:18382765 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15975920) Ensembl
MGI
TreeGrafter		 PMID:15975920 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b acts_upstream_of_or_within ISO (PMID:15671031) MGI PMID:15671031 NCBI chr 3:11,407,426...11,427,317 JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b involved_in IEA TreeGrafter GO_REF:0000118
G ROR2 receptor tyrosine kinase like orphan receptor 2 acts_upstream_of_or_within ISO (PMID:20660756) MGI PMID:20660756 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G SCX scleraxis bHLH transcription factor involved_in ISO (MGI:4418577|PMID:20059955) UniProt PMID:20059955 MGI:4418577 NCBI chr13:37,701,781...37,704,949
Ensembl chr13:37,703,232...37,704,657 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of ISO (PMID:19850029) MGI PMID:19850029 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SLC39A5 solute carrier family 39 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:552,755...557,319 JBrowse link
G SMAD1 SMAD family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15198985)
(PMID:19224984)
(PMID:16604073)
(PMID:25100727)		 RGD
MGI
TreeGrafter
Ensembl		 PMID:15198985 PMID:16020542 PMID:16604073 PMID:19224984 PMID:25100727 GO_REF:0000107 GO_REF:0000118 RGD:1643232 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD5 SMAD family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19224984)
(PMID:18590716)		 Ensembl
MGI
TreeGrafter		 PMID:18590716 PMID:19224984 GO_REF:0000107 GO_REF:0000118 NCBI chr11:24,027,603...24,082,673
Ensembl chr11:24,028,126...24,078,169 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD9 SMAD family member 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716)
(PMID:19224984)		 TreeGrafter
MGI		 PMID:18590716 PMID:19224984 GO_REF:0000118 NCBI chr25:3,768,851...3,844,645
Ensembl chr25:3,779,197...3,841,321 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24505141) Ensembl
MGI		 PMID:24505141 GO_REF:0000107 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SOST sclerostin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17002572) Ensembl
MGI		 PMID:17002572 GO_REF:0000107 NCBI chr 9:19,538,713...19,544,650
Ensembl chr 9:19,539,435...19,544,651 		JBrowse link
G SOSTDC1 sclerostin domain containing 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16179481) Ensembl
MGI		 PMID:16179481 GO_REF:0000107 NCBI chr14:31,035,759...31,079,139
Ensembl chr14:31,022,766...31,026,737
Ensembl chr14:31,022,766...31,026,737 		JBrowse link
G SPART spartin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22619377) Ensembl
MGI		 PMID:22619377 GO_REF:0000107 NCBI chr25:4,256,177...4,302,854
Ensembl chr25:4,232,533...4,316,363 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of ISO (PMID:17919533) MGI PMID:17919533 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:25382630) Ensembl
MGI		 PMID:25382630 GO_REF:0000107 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TMEM100 transmembrane protein 100 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:30,695,711...30,701,730
Ensembl chr 9:30,696,765...30,697,169 		JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19751239) Ensembl
MGI		 PMID:19751239 GO_REF:0000107 NCBI chr10:27,393,650...27,435,893
Ensembl chr10:27,397,123...27,435,908 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14681194) Ensembl
MGI		 PMID:14681194 GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,510,759...5,634,954
Ensembl chr10:5,510,022...5,634,202 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:19135894) UniProt PMID:19135894 NCBI chr  X:35,522,873...35,676,086 JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:20042595)
(PMID:22751012)		 MGI PMID:20042595 PMID:22751012 NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
G ZCCHC12 zinc finger CCHC-type containing 12 acts_upstream_of_or_within ISO (PMID:19416967) MGI PMID:19416967 NCBI chr  X:91,004,777...91,008,019 JBrowse link
G ZNF8 zinc finger protein 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12370310) Ensembl
MGI		 PMID:12370310 GO_REF:0000107 NCBI chr 1:99,644,778...99,654,993
Ensembl chr 1:99,642,446...99,655,014 		JBrowse link
negative regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:16720724) BHF-UCL PMID:16720724 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046 		JBrowse link
G FST follistatin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:61,779,252...61,785,666
Ensembl chr 4:61,779,259...61,783,260 		JBrowse link
G FSTL3 follistatin like 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
G IGSF1 immunoglobulin superfamily member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:102,359,980...102,376,838
Ensembl chr  X:102,359,986...102,377,018 		JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:7,775,995...7,833,895
Ensembl chr10:7,777,946...7,834,107 		JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISO (MGI:1353670|PMID:10681527) UniProt PMID:10681527 MGI:1353670 NCBI chr18:17,973,058...19,098,785
Ensembl chr18:17,918,928...18,930,059 		JBrowse link
G SKI SKI proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,144,178...57,216,385
Ensembl chr 5:57,145,825...57,214,403 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SYNJ2BP synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) UniProt PMID:16648306 MGI:3623710 NCBI chr 8:44,044,526...44,079,002
Ensembl chr 8:44,044,526...44,079,002 		JBrowse link
negative regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22729085) Ensembl
MGI		 PMID:22729085 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21743293) ARUK-UCL
Ensembl		 PMID:21743293 GO_REF:0000107 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G BMPER BMP binding endothelial regulator acts_upstream_of_or_within ISO (PMID:12897139) MGI PMID:12897139 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:15657086) BHF-UCL PMID:15657086 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9431803), (PMID:9501024) Ensembl
MGI		 PMID:9431803 PMID:9501024 GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G CHRD chordin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15780974), (PMID:19850029) Ensembl
MGI
TreeGrafter		 PMID:15780974 PMID:19850029 GO_REF:0000107 GO_REF:0000118 NCBI chr34:17,255,770...17,264,776
Ensembl chr34:17,255,562...17,271,713 		JBrowse link
G CHRDL1 chordin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23676271) Ensembl
MGI
TreeGrafter		 PMID:23676271 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:83,816,131...83,936,497
Ensembl chr  X:83,817,880...83,936,949 		JBrowse link
G CHRDL2 chordin like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14660436) TreeGrafter
MGI		 PMID:14660436 GO_REF:0000118 NCBI chr21:23,670,257...23,702,788
Ensembl chr21:23,670,238...23,702,788 		JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21743293) ARUK-UCL
Ensembl		 PMID:21743293 GO_REF:0000107 NCBI chr17:28,857,702...29,042,399
Ensembl chr17:28,857,696...29,040,002 		JBrowse link
G CTDSPL2 CTD small phosphatase like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25100727) Ensembl
MGI		 PMID:25100727 GO_REF:0000107 NCBI chr30:11,109,571...11,194,985
Ensembl chr30:11,109,664...11,193,534 		JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO (PMID:19850029) MGI PMID:19850029 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:16,485,158...16,489,397
Ensembl chr36:16,484,859...16,487,886 		JBrowse link
G FSTL3 follistatin like 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11010968) Ensembl
MGI		 PMID:11010968 GO_REF:0000107 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
G FZD1 frizzled class receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14627707) Ensembl
MGI		 PMID:14627707 GO_REF:0000107 NCBI chr14:17,046,911...17,050,515
Ensembl chr14:17,047,382...17,049,337 		JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:37,125,845...37,129,567
Ensembl chr27:37,125,928...37,129,484 		JBrowse link
G GPR155 G protein-coupled receptor 155 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr36:18,481,269...18,524,733
Ensembl chr36:18,482,910...18,520,192 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17522159) Ensembl
MGI		 PMID:17522159 GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:32,048,151...32,157,698
Ensembl chr 7:32,048,183...32,157,146 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20065295) Ensembl
MGI		 PMID:20065295 GO_REF:0000107 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G HTRA1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14973287) Ensembl
MGI		 PMID:14973287 GO_REF:0000107 NCBI chr28:32,133,779...32,157,835
Ensembl chr28:32,132,547...32,157,409 		JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:60,081,087...60,111,847
Ensembl chr 3:60,081,087...60,111,170 		JBrowse link
G LEMD2 LEM domain nuclear envelope protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:3,114,175...3,131,779
Ensembl chr12:3,115,460...3,131,919 		JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:7,775,995...7,833,895
Ensembl chr10:7,777,946...7,834,107 		JBrowse link
G LRP2 LDL receptor related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:13,910,450...14,107,081
Ensembl chr36:13,911,865...14,107,546 		JBrowse link
G MIR125B-1 microRNA mir-125b-1 acts_upstream_of ISO (PMID:28214897) BHF-UCL PMID:28214897 NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745 		JBrowse link
G MIR125B-2 microRNA mir-125b-2 acts_upstream_of ISO (PMID:28214897) BHF-UCL PMID:28214897 NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052 		JBrowse link
G MIR195 microRNA mir-195 involved_in ISO (PMID:31921616) BHF-UCL PMID:31921616 NCBI chr 5:32,045,450...32,045,510
Ensembl chr 5:32,045,450...32,045,510 		JBrowse link
G MIR199-1 microRNA mir-199-1 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr20:50,410,924...50,410,984
Ensembl chr20:50,410,913...50,410,994 		JBrowse link
G MIR199-2 microRNA mir-199-2 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr 7:26,812,766...26,812,824
Ensembl chr 7:26,812,735...26,812,838 		JBrowse link
G MIR199-3 microRNA mir-199-3 involved_in ISO (PMID:32082362) BHF-UCL PMID:32082362 NCBI chr 9:55,262,354...55,262,412
Ensembl chr 9:55,262,328...55,262,437 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:22450430) BHF-UCL PMID:22450430 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR214 microRNA mir-214 acts_upstream_of ISO (PMID:30703347) BHF-UCL PMID:30703347 NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670 		JBrowse link
G MIR26A-1 microRNA mir-26a-1 involved_in ISO (PMID:24047927) BHF-UCL PMID:24047927 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140 		JBrowse link
G MIR26A-2 microRNA mir-26a-2 involved_in ISO (PMID:24047927) BHF-UCL PMID:24047927 NCBI chr10:1,880,513...1,880,572
Ensembl chr10:1,880,513...1,880,572 		JBrowse link
G MIR302C microRNA mir-302c acts_upstream_of ISO (PMID:22988237) BHF-UCL PMID:22988237 NCBI chr32:32,429,366...32,429,433
Ensembl chr32:32,429,366...32,429,433 		JBrowse link
G MIR885 microRNA mir-885 acts_upstream_of ISO (PMID:24882581) BHF-UCL PMID:24882581 NCBI chr20:7,968,529...7,968,602
Ensembl chr20:7,968,529...7,968,602 		JBrowse link
G MIR93 microRNA mir-93 acts_upstream_of ISO (PMID:28797104) BHF-UCL PMID:28797104 NCBI chr 6:9,498,780...9,498,840 JBrowse link
G MIR98 microRNA mir-98 acts_upstream_of ISO (PMID:27860183) BHF-UCL PMID:27860183 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775 		JBrowse link
G MIR99A-2 microRNA mir-99a-2 acts_upstream_of ISO (PMID:22684006) BHF-UCL PMID:22684006 NCBI chr 5:12,047,369...12,047,425
Ensembl chr 5:12,047,369...12,047,425 		JBrowse link
G MTMR4 myotubularin related protein 4 involved_in ISO (PMID:23150675) FlyBase PMID:23150675 NCBI chr 9:33,110,983...33,136,843
Ensembl chr 9:33,112,143...33,136,684 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:16801560) MGI PMID:16801560 NCBI chr27:37,262,558...37,266,449 JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23676271) Ensembl
MGI		 PMID:23676271 GO_REF:0000107 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16712836)
(PMID:19852960)
(PMID:15110716), (PMID:15975920), (PMID:18462699), (PMID:19850029)		 UniProt
MGI
TreeGrafter
Ensembl
InterPro		 PMID:15110716 PMID:15975920 PMID:16712836 PMID:18462699 PMID:19850029 More... GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25100727) Ensembl
MGI		 PMID:25100727 GO_REF:0000107 NCBI chr 8:35,336,055...35,384,249
Ensembl chr 8:35,336,140...35,377,551 		JBrowse link
G PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr34:17,180,119...17,189,298
Ensembl chr34:17,180,098...17,189,303 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:19850029) MGI PMID:19850029 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SKI SKI proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21937600) Ensembl
MGI
TreeGrafter		 PMID:21937600 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:57,144,178...57,216,385
Ensembl chr 5:57,145,825...57,214,403 		JBrowse link
G SKIL SKI like proto-oncogene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr34:34,871,770...34,898,681
Ensembl chr34:34,871,574...34,894,854 		JBrowse link
G SKOR1 SKI family transcriptional corepressor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:31,935,860...31,948,161
Ensembl chr30:31,938,869...31,948,218 		JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21937600) TreeGrafter
MGI		 PMID:21937600 GO_REF:0000118 NCBI chr 7:44,250,822...44,289,737 JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:12,348,777...12,472,636
Ensembl chr 9:12,351,627...12,471,467 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784 		JBrowse link
G SOST sclerostin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14633986)
(PMID:17002572)		 MGI
TreeGrafter
Ensembl		 PMID:14633986 PMID:17002572 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:19,538,713...19,544,650
Ensembl chr 9:19,539,435...19,544,651 		JBrowse link
G SOSTDC1 sclerostin domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14623234), (PMID:16179481)
(PMID:16179481)		 Ensembl
MGI
TreeGrafter		 PMID:14623234 PMID:16179481 GO_REF:0000107 GO_REF:0000118 NCBI chr14:31,035,759...31,079,139
Ensembl chr14:31,022,766...31,026,737
Ensembl chr14:31,022,766...31,026,737 		JBrowse link
G SPART spartin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22619377) Ensembl
MGI
TreeGrafter		 PMID:22619377 GO_REF:0000107 GO_REF:0000118 NCBI chr25:4,256,177...4,302,854
Ensembl chr25:4,232,533...4,316,363 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:17919533) MGI PMID:17919533 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737 		JBrowse link
G TMEM53 transmembrane protein 53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:15,640,232...15,661,829
Ensembl chr15:15,640,342...15,678,994 		JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19751239) Ensembl
MGI		 PMID:19751239 GO_REF:0000107 NCBI chr10:27,393,650...27,435,893
Ensembl chr10:27,397,123...27,435,908 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,607,598...52,623,799
Ensembl chr19:52,607,713...52,623,811 		JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11163184) Ensembl
MGI		 PMID:11163184 GO_REF:0000107 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
Ensembl chr 9:26,736,675...26,740,177 		JBrowse link
G TRIM33 tripartite motif containing 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,117,085...52,230,846
Ensembl chr17:52,118,476...52,230,530 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15780974)
(PMID:12665593)		 Ensembl
MGI		 PMID:12665593 PMID:15780974 GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G VWC2 von Willebrand factor C domain containing 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:1,248,612...1,350,965
Ensembl chr18:1,257,357...1,350,856 		JBrowse link
G VWC2L von Willebrand factor C domain containing 2 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19852960) Ensembl
MGI
TreeGrafter		 PMID:19852960 GO_REF:0000107 GO_REF:0000118 NCBI chr37:21,690,649...21,845,435
Ensembl chr37:21,694,137...21,842,599 		JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
negative regulation of nodal receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LEFTY1 left-right determination factor 1 involved_in ISO (MGI:3042530|PMID:15062104) UniProt PMID:15062104 MGI:3042530 NCBI chr 7:38,932,668...38,934,989 JBrowse link
negative regulation of nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DACT2 dishevelled binding antagonist of beta catenin 2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:55,726,041...55,736,548
Ensembl chr 1:55,726,819...55,736,505 		JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
G LEFTY1 left-right determination factor 1 involved_in ISO (MGI:3042530|PMID:15062104) UniProt PMID:15062104 MGI:3042530 NCBI chr 7:38,932,668...38,934,989 JBrowse link
negative regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN3 cellular communication network factor 3 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 (MGI:5504324|PMID:23653360) Ensembl
UniProt		 PMID:23653360 GO_REF:0000107 MGI:5504324 NCBI chr13:18,507,586...18,515,755
Ensembl chr13:18,507,580...18,514,619 		JBrowse link
G CILP cartilage intermediate layer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:29,573,072...29,587,601
Ensembl chr30:29,573,184...29,650,883 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:21,071,502...21,078,888
Ensembl chr17:21,071,580...21,078,889 		JBrowse link
G FAM89B family with sequence similarity 89 member B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:51,632,509...51,634,218
Ensembl chr18:51,632,781...51,634,034 		JBrowse link
G GDF15 growth differentiation factor 15 involved_in ISO (PMID:25893289) UniProt PMID:25893289 NCBI chr20:44,633,131...44,636,842
Ensembl chr20:44,634,588...44,636,821 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in ISO (PMID:24627487) UniProt PMID:24627487 NCBI chr 1:24,541,702...24,927,435
Ensembl chr 1:24,541,811...24,925,464 		JBrowse link
G LOC612523 EP300-interacting inhibitor of differentiation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,712,193...113,713,420 JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271 		JBrowse link
G MIR101-1 microRNA mir-101-1 involved_in ISO (PMID:27693460) BHF-UCL PMID:27693460 NCBI chr 5:45,184,774...45,184,828
Ensembl chr 5:45,184,759...45,184,841 		JBrowse link
G MIR101-2 microRNA mir-101-2 involved_in ISO (PMID:27693460) BHF-UCL PMID:27693460 NCBI chr 1:93,194,328...93,194,382
Ensembl chr 1:93,194,309...93,194,399 		JBrowse link
G MIR130A microRNA mir-130a acts_upstream_of ISO (PMID:30741461) BHF-UCL PMID:30741461 NCBI chr18:38,543,618...38,543,679
Ensembl chr18:38,543,618...38,543,681 		JBrowse link
G MIR140 microRNA mir-140 acts_upstream_of ISO (PMID:24928442) BHF-UCL PMID:24928442 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR145 microRNA mir-145 involved_in ISO (PMID:25704091) BHF-UCL PMID:25704091 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210 		JBrowse link
G MIR195 microRNA mir-195 involved_in ISO (PMID:31921616) BHF-UCL PMID:31921616 NCBI chr 5:32,045,450...32,045,510
Ensembl chr 5:32,045,450...32,045,510 		JBrowse link
G MIR199-1 microRNA mir-199-1 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr20:50,410,924...50,410,984
Ensembl chr20:50,410,913...50,410,994 		JBrowse link
G MIR199-2 microRNA mir-199-2 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr 7:26,812,766...26,812,824
Ensembl chr 7:26,812,735...26,812,838 		JBrowse link
G MIR204 microRNA mir-204 involved_in ISO (PMID:23221074) BHF-UCL PMID:23221074 NCBI chr 1:86,818,494...86,818,553
Ensembl chr 1:86,818,489...86,818,556 		JBrowse link
G MIR205 microRNA mir-205 acts_upstream_of ISO (PMID:25012146)
(PMID:23800974)		 BHF-UCL PMID:23800974 PMID:25012146 NCBI chr 7:8,090,511...8,090,579
Ensembl chr 7:8,090,511...8,090,579 		JBrowse link
G MIR23A microRNA mir-23a acts_upstream_of ISO (PMID:26400397) BHF-UCL PMID:26400397 NCBI chr20:48,620,335...48,620,386
Ensembl chr20:48,620,323...48,620,397 		JBrowse link
G MIR26B microRNA mir-26b involved_in ISO (PMID:27027434) BHF-UCL PMID:27027434 NCBI chr37:25,054,488...25,054,543 JBrowse link
G MIR27A microRNA mir-27a acts_upstream_of ISO (PMID:26400397) BHF-UCL PMID:26400397 NCBI chr20:48,620,556...48,620,615
Ensembl chr20:48,620,556...48,620,615 		JBrowse link
G MIR323 microRNA mir-323 involved_in ISO (PMID:26908446) BHF-UCL PMID:26908446 NCBI chr 8:69,257,494...69,257,549
Ensembl chr 8:69,257,479...69,257,564 		JBrowse link
G MIR885 microRNA mir-885 acts_upstream_of ISO (PMID:24882581) BHF-UCL PMID:24882581 NCBI chr20:7,968,529...7,968,602
Ensembl chr20:7,968,529...7,968,602 		JBrowse link
G MIRLET7G microRNA let-7g involved_in ISO (PMID:24291274) BHF-UCL PMID:24291274 NCBI chr20:37,501,074...37,501,152
Ensembl chr20:37,501,054...37,501,160 		JBrowse link
G NOG noggin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:5,020,608...5,050,487
Ensembl chr24:5,020,813...5,050,309 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:51,156,887...51,168,131
Ensembl chr20:51,157,121...51,168,136 		JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:42,602,608...42,637,569
Ensembl chr24:42,602,595...42,656,209 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:28467929), (PMID:31023188) BHF-UCL PMID:28467929 PMID:31023188 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G SKI SKI proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,144,178...57,216,385
Ensembl chr 5:57,145,825...57,214,403 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G TBX20 T-box transcription factor 20 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19661464) Ensembl
MGI		 PMID:19661464 GO_REF:0000107 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G UCMA upper zone of growth plate and cartilage matrix associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:23,287,410...23,307,116
Ensembl chr 2:23,287,551...23,298,035 		JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:50,779,456...51,002,681
Ensembl chr23:50,773,610...51,003,043 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
negative regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731 		JBrowse link
G ADAMTSL2 ADAMTS like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25762570) Ensembl
MGI		 PMID:25762570 GO_REF:0000107 NCBI chr 9:49,925,738...49,958,870
Ensembl chr 9:49,925,755...49,958,300 		JBrowse link
G ASPN asporin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,881,610...98,905,641
Ensembl chr 1:98,881,690...98,904,945 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G BCL9L BCL9 like involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:14,893,548...14,919,121
Ensembl chr 5:14,900,208...14,919,193 		JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28467929) ARUK-UCL
Ensembl		 PMID:28467929 GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G CAV2 caveolin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21832243) Ensembl
MGI		 PMID:21832243 GO_REF:0000107 NCBI chr14:55,437,622...55,445,481
Ensembl chr14:55,437,622...55,445,469 		JBrowse link
G CD109 CD109 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:35,712,589...35,839,153
Ensembl chr12:35,712,271...35,839,044 		JBrowse link
G CDH3 cadherin 3 involved_in
acts_upstream_of_or_within_negative_effect		 IEA
ISO		 (PMID:22696062) Ensembl
UniProt		 PMID:22696062 GO_REF:0000107 NCBI chr 5:80,864,859...80,912,136
Ensembl chr 5:80,863,661...80,913,019 		JBrowse link
G CHST11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16079159) Ensembl
MGI		 PMID:16079159 GO_REF:0000107 NCBI chr10:33,555,629...33,810,808
Ensembl chr10:33,555,628...33,810,558 		JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:77,685,383...77,703,320
Ensembl chr 7:77,684,863...77,702,934 		JBrowse link
G CILP cartilage intermediate layer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:29,573,072...29,587,601
Ensembl chr30:29,573,184...29,650,883 		JBrowse link
G CRIPTO cripto, EGF-CFC family member acts_upstream_of_or_within ISO (PMID:17991893) MGI PMID:17991893 NCBI chr20:42,137,939...42,140,590 JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14721776) Ensembl
MGI		 PMID:14721776 GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:25100282 RGD:9685289 NCBI chr20:50,398,866...50,487,303
Ensembl chr20:50,398,864...50,487,241 		JBrowse link
G EMILIN1 elastin microfibril interfacer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:21,071,502...21,078,888
Ensembl chr17:21,071,580...21,078,889 		JBrowse link
G FAM89B family with sequence similarity 89 member B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:51,632,509...51,634,218
Ensembl chr18:51,632,781...51,634,034 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A involved_in ISO (PMID:11583628) FlyBase PMID:11583628 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046 		JBrowse link
G GDF15 growth differentiation factor 15 involved_in ISO (PMID:25893289) GO_Central PMID:25893289 NCBI chr20:44,633,131...44,636,842
Ensembl chr20:44,634,588...44,636,821 		JBrowse link
G GLG1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20530870) Ensembl
MGI		 PMID:20530870 GO_REF:0000107 NCBI chr 5:76,020,743...76,171,477
Ensembl chr 5:76,020,084...76,167,007 		JBrowse link
G HSP70 heat shock protein 70 involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr12:1,285,282...1,287,670 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17991893) Ensembl
MGI		 PMID:17991893 GO_REF:0000107 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257 		JBrowse link
G HTRA1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14973287) Ensembl
MGI		 PMID:14973287 GO_REF:0000107 NCBI chr28:32,133,779...32,157,835
Ensembl chr28:32,132,547...32,157,409 		JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:60,081,087...60,111,847
Ensembl chr 3:60,081,087...60,111,170 		JBrowse link
G IL17RD interleukin 17 receptor D involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,240,728...33,306,727
Ensembl chr20:33,240,767...33,303,404 		JBrowse link
G INTS9 integrator complex subunit 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,679,470...28,779,931
Ensembl chr25:28,679,465...28,904,332 		JBrowse link
G KIAA1586 KIAA1586 ortholog involved_in IEA Ensembl GO_REF:0000107
G LDLRAD4 low density lipoprotein receptor class A domain containing 4 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 1:24,541,702...24,927,435
Ensembl chr 1:24,541,811...24,925,464 		JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:7,775,995...7,833,895
Ensembl chr10:7,777,946...7,834,107 		JBrowse link
G LOC612523 EP300-interacting inhibitor of differentiation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,712,193...113,713,420 JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271 		JBrowse link
G MECOM MDS1 and EVI1 complex locus NOT|involved_in ISO (PMID:15897867) UniProt PMID:15897867 NCBI chr34:33,747,495...34,299,389
Ensembl chr34:33,748,843...34,299,276 		JBrowse link
G MIR101-1 microRNA mir-101-1 involved_in ISO (PMID:27693460) BHF-UCL PMID:27693460 NCBI chr 5:45,184,774...45,184,828
Ensembl chr 5:45,184,759...45,184,841 		JBrowse link
G MIR101-2 microRNA mir-101-2 involved_in ISO (PMID:27693460) BHF-UCL PMID:27693460 NCBI chr 1:93,194,328...93,194,382
Ensembl chr 1:93,194,309...93,194,399 		JBrowse link
G MIR140 microRNA mir-140 involved_in ISO (PMID:23401231) BHF-UCL PMID:23401231 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR142 microRNA mir-142 involved_in ISO (PMID:26572508)
(PMID:24558198)		 BHF-UCL PMID:24558198 PMID:26572508 NCBI chr 9:32,977,393...32,977,455
Ensembl chr 9:32,977,382...32,977,468 		JBrowse link
G MIR145 microRNA mir-145 involved_in ISO (PMID:25323858) BHF-UCL PMID:25323858 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210 		JBrowse link
G MIR17 microRNA mir-17 involved_in ISO (PMID:21145484) BHF-UCL PMID:21145484 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083 		JBrowse link
G MIR181A-1 microRNA mir-181a-1 involved_in ISO (PMID:22714950) BHF-UCL PMID:22714950 NCBI chr 7:4,055,465...4,055,526
Ensembl chr 7:4,055,465...4,055,526 		JBrowse link
G MIR181A-2 microRNA mir-181a-2 involved_in ISO (PMID:22714950) BHF-UCL PMID:22714950 NCBI chr 9:58,302,547...58,302,606
Ensembl chr 9:58,302,547...58,302,606 		JBrowse link
G MIR18A microRNA mir-18a involved_in ISO (PMID:21145484)
(PMID:28131417)		 BHF-UCL PMID:21145484 PMID:28131417 NCBI chr22:42,478,138...42,478,229
Ensembl chr22:42,478,138...42,478,229 		JBrowse link
G MIR199-1 microRNA mir-199-1 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr20:50,410,924...50,410,984
Ensembl chr20:50,410,913...50,410,994 		JBrowse link
G MIR199-2 microRNA mir-199-2 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr 7:26,812,766...26,812,824
Ensembl chr 7:26,812,735...26,812,838 		JBrowse link
G MIR19A microRNA mir-19a involved_in ISO (PMID:27098600)
(PMID:29130787)		 BHF-UCL PMID:27098600 PMID:29130787 NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366 		JBrowse link
G MIR19B-1 microRNA mir-19b-1 involved_in ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr22:42,478,598...42,478,656 JBrowse link
G MIR19B-2 microRNA mir-19b-2 involved_in ISO (PMID:27098600) BHF-UCL PMID:27098600 NCBI chr  X:104,895,962...104,896,025
Ensembl chr  X:104,895,962...104,896,025 		JBrowse link
G MIR204 microRNA mir-204 involved_in ISO (PMID:23221074) BHF-UCL PMID:23221074 NCBI chr 1:86,818,494...86,818,553
Ensembl chr 1:86,818,489...86,818,556 		JBrowse link
G MIR20A microRNA mir-20a involved_in
acts_upstream_of		 ISO (PMID:21145484)
(PMID:31368162)		 BHF-UCL PMID:21145484 PMID:31368162 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:28095798) BHF-UCL PMID:28095798 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191 		JBrowse link
G MIR29B-1 microRNA mir-29b-1 involved_in ISO (PMID:26687115) BHF-UCL PMID:26687115 NCBI chr14:6,184,457...6,184,521
Ensembl chr14:6,184,446...6,184,531 		JBrowse link
G MIR29B-2 microRNA mir-29b-2 involved_in ISO (PMID:26687115) BHF-UCL PMID:26687115 NCBI chr 7:6,651,878...6,651,943
Ensembl chr 7:6,651,866...6,651,955 		JBrowse link
G MIR302B microRNA mir-302b involved_in ISO (PMID:21490602) BHF-UCL PMID:21490602 NCBI chr32:32,429,500...32,429,574
Ensembl chr32:32,429,500...32,429,574 		JBrowse link
G MIR323 microRNA mir-323 involved_in ISO (PMID:26908446) BHF-UCL PMID:26908446 NCBI chr 8:69,257,494...69,257,549
Ensembl chr 8:69,257,479...69,257,564 		JBrowse link
G MIR342 microRNA mir-342 involved_in ISO (PMID:26857067) BHF-UCL PMID:26857067 NCBI chr 8:68,424,656...68,424,718 JBrowse link
G MIR361 microRNA mir-361 involved_in ISO (PMID:31694982) BHF-UCL PMID:31694982 NCBI chr  X:66,698,698...66,698,760
Ensembl chr  X:66,698,698...66,698,760 		JBrowse link
G MIR371 microRNA mir-371 involved_in ISO (PMID:21490602) BHF-UCL PMID:21490602 NCBI chr 1:103,406,620...103,406,679
Ensembl chr 1:103,406,620...103,406,679 		JBrowse link
G MIR424 microRNA mir-424 involved_in ISO (PMID:29130787) BHF-UCL PMID:29130787 NCBI chr  X:105,183,437...105,183,493
Ensembl chr  X:105,183,437...105,183,493 		JBrowse link
G MIR490 microRNA mir-490 involved_in ISO (PMID:26714817) BHF-UCL PMID:26714817 NCBI chr16:11,628,312...11,628,392
Ensembl chr16:11,628,312...11,628,392 		JBrowse link
G MIR497 microRNA mir-497 involved_in ISO (PMID:29969696) BHF-UCL PMID:29969696 NCBI chr 5:32,045,759...32,045,825
Ensembl chr 5:32,045,759...32,045,825 		JBrowse link
G MIR9-2 microRNA mir-9-2 involved_in ISO (PMID:26315535) BHF-UCL PMID:26315535 NCBI chr 3:19,997,697...19,997,756
Ensembl chr 3:19,997,682...19,997,768 		JBrowse link
G MIR9-3 microRNA mir-9-3 involved_in ISO (PMID:26315535) BHF-UCL PMID:26315535 NCBI chr 3:52,410,840...52,410,900
Ensembl chr 3:52,410,825...52,410,914 		JBrowse link
G MIR93 microRNA mir-93 involved_in ISO (PMID:24606633) BHF-UCL PMID:24606633 NCBI chr 6:9,498,780...9,498,840 JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:28251559) BHF-UCL PMID:28251559 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775 		JBrowse link
G MIRLET7A-1 microRNA let-7a-1 involved_in ISO (PMID:30467960) BHF-UCL PMID:30467960 NCBI chr10:20,034,319...20,034,387
Ensembl chr10:20,034,319...20,034,387 		JBrowse link
G MIRLET7A-2 microRNA let-7a-2 involved_in ISO (PMID:30467960) BHF-UCL PMID:30467960 NCBI chr 5:12,052,786...12,052,881
Ensembl chr 5:12,052,786...12,052,881 		JBrowse link
G MIRLET7F microRNA let-7f involved_in ISO (PMID:28345812) BHF-UCL PMID:28345812 NCBI chr 1:97,903,931...97,904,008
Ensembl chr 1:97,903,919...97,904,028 		JBrowse link
G MIRLET7G microRNA let-7g involved_in ISO (PMID:24291274) BHF-UCL PMID:24291274 NCBI chr20:37,501,074...37,501,152
Ensembl chr20:37,501,054...37,501,160 		JBrowse link
G NEPN nephrocan involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,837,927...57,859,346 JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in IEA Ensembl GO_REF:0000107
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16103213) Ensembl
MGI		 PMID:16103213 GO_REF:0000107 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497 		JBrowse link
G ONECUT2 one cut homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16103213) Ensembl
MGI		 PMID:16103213 GO_REF:0000107 NCBI chr 1:18,428,112...18,486,047
Ensembl chr 1:18,440,172...18,486,048 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:5,020,608...5,050,487
Ensembl chr24:5,020,813...5,050,309 		JBrowse link
G PBLD phenazine biosynthesis like protein domain containing involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 (PMID:23687415) Ensembl
UniProt		 PMID:23687415 GO_REF:0000107 NCBI chr 4:19,514,256...19,558,515
Ensembl chr 4:19,515,050...19,558,335 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PEG10 paternally expressed 10 involved_in ISO (PMID:15611116) HGNC-UCL PMID:15611116 NCBI chr14:20,121,414...20,134,133
Ensembl chr14:20,121,414...20,134,133 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:51,156,887...51,168,131
Ensembl chr20:51,157,121...51,168,136 		JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr24:42,602,608...42,637,569
Ensembl chr24:42,602,595...42,656,209 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO (PMID:31611175) ARUK-UCL PMID:31611175 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within
involved_in		 ISO (PMID:28467929)
(PMID:31023188)		 ARUK-UCL
BHF-UCL		 PMID:28467929 PMID:31023188 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:35,336,055...35,384,249
Ensembl chr 8:35,336,140...35,377,551 		JBrowse link
G PRDM16 PR/SET domain 16 NOT|involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:14656887)
(PMID:20007998)		 UniProt
MGI
Ensembl		 PMID:14656887 PMID:20007998 GO_REF:0000107 NCBI chr 5:57,805,951...58,018,817
Ensembl chr 5:57,730,370...58,017,976 		JBrowse link
G RASL11B RAS like family 11 member B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15239668) Ensembl
MGI		 PMID:15239668 GO_REF:0000107 NCBI chr13:45,579,587...45,583,945
Ensembl chr13:45,579,417...45,583,503 		JBrowse link
G RYR1 ryanodine receptor 1 ISO RGD PMID:32619649 RGD:329845531 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (MGI:5306300|PMID:17098745) UniProt PMID:17098745 MGI:5306300 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SKI SKI proto-oncogene acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15312649)
(PMID:21937600)		 MGI
Ensembl		 PMID:15312649 PMID:21937600 GO_REF:0000107 NCBI chr 5:57,144,178...57,216,385
Ensembl chr 5:57,145,825...57,214,403 		JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15677329) Ensembl
MGI		 PMID:15677329 GO_REF:0000107 NCBI chr34:34,871,770...34,898,681
Ensembl chr34:34,871,574...34,894,854 		JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
NOT|acts_upstream_of_or_within		 IEA
ISO		 (PMID:21937600) Ensembl
MGI		 PMID:21937600 GO_REF:0000107 NCBI chr 7:44,250,822...44,289,737 JBrowse link
G SLC2A10 solute carrier family 2 member 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16550171), (PMID:26376865) ARUK-UCL
Ensembl		 PMID:16550171 PMID:26376865 GO_REF:0000107 NCBI chr24:33,905,099...33,920,604
Ensembl chr24:33,905,203...33,919,454 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:12,348,777...12,472,636
Ensembl chr 9:12,351,627...12,471,467 		JBrowse link
G SNX1 sorting nexin 1 acts_upstream_of_or_within ISO (PMID:15239668) MGI PMID:15239668 NCBI chr30:28,597,928...28,642,847
Ensembl chr30:28,597,989...28,642,535 		JBrowse link
G SNX25 sorting nexin 25 involved_in ISO (PMID:21266196)
(MGI:5545984|PMID:21266196)		 UniProt PMID:21266196 MGI:5545984 NCBI chr16:45,269,434...45,411,890
Ensembl chr16:45,269,412...45,403,719 		JBrowse link
G SNX6 sorting nexin 6 involved_in ISO (PMID:11279102) HGNC-UCL PMID:11279102 NCBI chr 8:13,460,676...13,520,282
Ensembl chr 8:13,460,947...13,520,423 		JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:5,594,327...5,716,082
Ensembl chr30:5,594,473...5,712,040 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr10:64,764,275...64,815,937
Ensembl chr10:64,764,311...64,867,009 		JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr 1:114,604,265...114,614,764
Ensembl chr 1:114,607,058...114,685,985 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr19:16,969,869...16,976,573
Ensembl chr19:16,970,904...16,972,089 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in ISO (MGI:6414689|PMID:25576668) UniProt PMID:25576668 MGI:6414689 NCBI chr22:33,366,139...33,371,102
Ensembl chr22:33,366,931...33,367,878 		JBrowse link
G STRAP serine/threonine kinase receptor associated protein involved_in
acts_upstream_of_or_within
acts_upstream_of_positive_effect		 IEA
ISO		 (PMID:9856985)
(PMID:23687415)		 Ensembl
MGI
UniProt		 PMID:9856985 PMID:23687415 GO_REF:0000107 NCBI chr27:30,800,853...30,817,578
Ensembl chr27:30,675,247...30,817,388 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573 		JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:12071374 RGD:730235 NCBI chr 8:48,920,874...48,946,037
Ensembl chr 8:48,923,423...48,945,816 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:10746731 RGD:1579946 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15657445) Ensembl
MGI		 PMID:15657445 GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,510,759...5,634,954
Ensembl chr10:5,510,022...5,634,202 		JBrowse link
G VASN vasorin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,014,704...37,025,734
Ensembl chr 6:37,015,333...37,017,351 		JBrowse link
G VEPH1 ventricular zone expressed PH domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:50,779,456...51,002,681
Ensembl chr23:50,773,610...51,003,043 		JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,934,105...39,937,666
Ensembl chr 6:39,934,068...39,936,628 		JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,711,470...26,717,625
Ensembl chr 9:26,711,959...26,716,348 		JBrowse link
G WNT1 Wnt family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16601693) Ensembl
MGI		 PMID:16601693 GO_REF:0000107 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,517,531...55,527,071
Ensembl chr20:55,505,916...55,523,736 		JBrowse link
G ZNF451 zinc finger protein 451 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:24,260,862...24,350,890
Ensembl chr12:24,260,917...24,350,559 		JBrowse link
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSTL3 follistatin like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G ACVR1C activin A receptor type 1C involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,534,231...3,583,310
Ensembl chr36:3,541,248...3,613,384 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995 		JBrowse link
G CRIPTO cripto, EGF-CFC family member involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:42,137,939...42,140,590 JBrowse link
G LOC609557 cryptic protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:20,318,937...20,384,369 JBrowse link
G NODAL nodal growth differentiation factor involved_in ISO (MGI:5315339|PMID:17507406), (MGI:5318034|PMID:12052855) UniProt PMID:12052855 PMID:17507406 MGI:5315339 MGI:5318034 NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151 		JBrowse link
G NOG noggin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G TGIF1 TGFB induced factor homeobox 1 acts_upstream_of_or_within ISO (PMID:20040491) MGI PMID:20040491 NCBI chr 7:70,040,376...70,048,346
Ensembl chr 7:70,040,508...70,047,912 		JBrowse link
G TGIF2 TGFB induced factor homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20040491) Ensembl
MGI		 PMID:20040491 GO_REF:0000107 NCBI chr24:25,360,363...25,375,531
Ensembl chr24:25,364,357...25,373,302 		JBrowse link
G VWDE von Willebrand factor D and EGF domains involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:27,183,263...27,280,746
Ensembl chr14:27,175,631...27,280,776 		JBrowse link
G ZIC2 Zic family member 2 acts_upstream_of_or_within ISO (PMID:24585447) MGI PMID:24585447 NCBI chr22:49,948,743...49,952,007
Ensembl chr22:49,948,778...49,950,055 		JBrowse link
positive regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in ISO (PMID:12665502) HGNC-UCL PMID:12665502 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:8622651) HGNC-UCL PMID:8622651 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418 		JBrowse link
G FGF9 fibroblast growth factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23034635) Ensembl
MGI		 PMID:23034635 GO_REF:0000107 NCBI chr25:16,630,321...16,665,935
Ensembl chr25:16,632,812...16,663,550 		JBrowse link
G NODAL nodal growth differentiation factor involved_in ISO (PMID:15150278) BHF-UCL PMID:15150278 NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151 		JBrowse link
G SYNJ2BP synaptojanin 2 binding protein involved_in ISO (MGI:3623710|PMID:16648306) UniProt PMID:16648306 MGI:3623710 NCBI chr 8:44,044,526...44,079,002
Ensembl chr 8:44,044,526...44,079,002 		JBrowse link
G ZC3H3 zinc finger CCCH-type containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16115198) Ensembl
MGI		 PMID:16115198 GO_REF:0000107 NCBI chr13:37,128,915...37,214,643
Ensembl chr13:37,130,999...37,214,997 		JBrowse link
positive regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G ARK2C arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23610558) Ensembl
MGI
TreeGrafter		 PMID:23610558 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:44,834,006...44,939,538
Ensembl chr 7:44,840,099...44,940,619 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994 		JBrowse link
G CDH5 cadherin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:82,830,505...82,863,931
Ensembl chr 5:82,830,939...82,863,882 		JBrowse link
G CRB2 crumbs cell polarity complex component 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:59,427,661...59,450,436
Ensembl chr 9:59,427,569...59,450,434 		JBrowse link
G ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:13,074,575...13,245,312
Ensembl chr14:13,076,932...13,245,319 		JBrowse link
G ENG endoglin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 involved_in ISS UniProt GO_REF:0000024 NCBI chr28:14,927,740...14,929,867
Ensembl chr28:14,927,532...14,929,863 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FOXD1 forkhead box D1 involved_in ISO (MGI:3525902|PMID:15634693) UniProt PMID:15634693 MGI:3525902
G GATA4 GATA binding protein 4 involved_in ISO PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr25:26,126,172...26,211,474
Ensembl chr25:26,127,853...26,182,989 		JBrowse link
G GATA6 GATA binding protein 6 involved_in ISO PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G GDF2 growth differentiation factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GPC3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15925496) Ensembl
MGI		 PMID:15925496 GO_REF:0000107 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388 		JBrowse link
G ILK integrin linked kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,911,326...29,917,972
Ensembl chr21:29,911,364...29,917,974 		JBrowse link
G KCP kielin cysteine rich BMP regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15793581) Ensembl
MGI
TreeGrafter		 PMID:15793581 GO_REF:0000107 GO_REF:0000118 NCBI chr14:7,752,162...7,776,428
Ensembl chr14:7,751,351...7,780,558 		JBrowse link
G KDR kinase insert domain receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G MIR140 microRNA mir-140 involved_in ISO (PMID:27214554) BHF-UCL PMID:27214554 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18667074) Ensembl
MGI		 PMID:18667074 GO_REF:0000107 NCBI chr 3:70,232,790...70,236,295
Ensembl chr 3:70,232,052...70,236,447 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:18667074) MGI PMID:18667074 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407 		JBrowse link
G NEO1 neogenin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20065295) Ensembl
MGI		 PMID:20065295 GO_REF:0000107 NCBI chr30:36,387,425...36,622,491
Ensembl chr30:36,387,259...36,622,154 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23676271) Ensembl
MGI		 PMID:23676271 GO_REF:0000107 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857 		JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:26,000,579...26,076,281
Ensembl chr21:26,037,095...26,075,549 		JBrowse link
G PELO pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO (PMID:24835669) MGI PMID:24835669 NCBI chr 4:62,440,923...62,443,598 JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360 		JBrowse link
G SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,383,649...4,420,844
Ensembl chr12:4,382,916...4,418,300 		JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in IEA Ensembl GO_REF:0000107
G SULF1 sulfatase 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr29:18,709,406...18,885,248
Ensembl chr29:18,709,445...18,884,378 		JBrowse link
G TBX20 T-box transcription factor 20 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5299248|PMID:21983003) BHF-UCL
Ensembl		 PMID:21983003 GO_REF:0000107 MGI:5299248 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (PMID:25382630) MGI PMID:25382630 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12665593) Ensembl
MGI		 PMID:12665593 GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G UBE2O ubiquitin conjugating enzyme E2 O involved_in ISO (PMID:23455153) UniProt PMID:23455153 NCBI chr 9:4,294,192...4,310,971
Ensembl chr 9:4,254,649...4,310,589 		JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:20042595) MGI PMID:20042595 NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687 		JBrowse link
G ZNF423 zinc finger protein 423 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,512,342...65,778,410
Ensembl chr 2:65,438,842...65,778,407 		JBrowse link
positive regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G AMH anti-Mullerian hormone involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,785,960...56,788,815 JBrowse link
G ATOH8 atonal bHLH transcription factor 8 involved_in ISO (PMID:24236640) UniProt PMID:24236640 NCBI chr17:39,255,725...39,280,022 JBrowse link
G B9D2 B9 domain containing 2 involved_in ISO (PMID:22714950)
(MGI:2663364|PMID:12773577)
(PMID:17438144), (PMID:17999987), (PMID:18453574), (PMID:19366691), (PMID:19736306), (PMID:25196641), (PMID:25893292), (PMID:26634652), (PMID:27693460), (PMID:28467929), (PMID:29167509), (PMID:31023188), (PMID:9389648)
(PMID:26908446)		 BHF-UCL PMID:9389648 PMID:12773577 PMID:17438144 PMID:17999987 PMID:18453574 More... MGI:2663364 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BMP10 bone morphogenetic protein 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:67,717,047...67,724,778
Ensembl chr10:67,717,980...67,724,739 		JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of
involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:3795340|PMID:18382765)
(PMID:18382765)		 BHF-UCL
Ensembl		 PMID:18382765 GO_REF:0000107 MGI:3795340 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18382765) BHF-UCL
Ensembl		 PMID:18382765 GO_REF:0000107 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G ENG endoglin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in ISO (PMID:28257634) UniProt PMID:28257634 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373 		JBrowse link
G GDF2 growth differentiation factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (PMID:16049014)
(PMID:26643732)		 BHF-UCL
UniProt		 PMID:16049014 PMID:26643732 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G GDF7 growth differentiation factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,627,739...15,636,513 JBrowse link
G GLCE glucuronic acid epimerase ISO RGD PMID:24499487 RGD:401793759 NCBI chr30:33,093,318...33,208,754
Ensembl chr30:33,110,947...33,206,095 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G INHBA inhibin subunit beta A involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794 		JBrowse link
G JAK2 Janus kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28334068) MGI
Ensembl		 PMID:28334068 GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G KIAA0319 KIAA0319 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28334068) MGI
Ensembl		 PMID:28334068 GO_REF:0000107 NCBI chr35:22,589,103...22,689,549
Ensembl chr35:22,591,353...22,652,292 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G NODAL nodal growth differentiation factor involved_in ISO (PMID:21741376) BHF-UCL PMID:21741376 NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151 		JBrowse link
G NUP93 nucleoporin 93 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,465,482...59,573,871
Ensembl chr 2:59,465,487...59,574,033 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (MGI:6434720|PMID:31023188) BHF-UCL PMID:31023188 MGI:6434720 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G SH2B1 SH2B adaptor protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28334068) MGI
Ensembl		 PMID:28334068 GO_REF:0000107 NCBI chr 6:18,370,881...18,380,965
Ensembl chr 6:18,371,832...18,380,962 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
G TGFB3 transforming growth factor beta 3 involved_in ISO (MGI:2683382|PMID:14691138) BHF-UCL PMID:14691138 MGI:2683382 NCBI chr 8:48,920,874...48,946,037
Ensembl chr 8:48,923,423...48,945,816 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
positive regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADISSP adipose secreted signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:17,586,111...17,600,147
Ensembl chr24:17,586,782...17,599,696 		JBrowse link
G AXIN1 axin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16601693) Ensembl
MGI		 PMID:16601693 GO_REF:0000107 NCBI chr 6:40,155,797...40,218,330
Ensembl chr 6:40,158,244...40,218,343 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in ISO (PMID:16943770) BHF-UCL PMID:16943770 NCBI chr18:46,860,636...46,861,697 JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995 		JBrowse link
G CREBBP CREB binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396 		JBrowse link
G FERMT1 FERM domain containing kindlin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,748,632...15,785,025
Ensembl chr24:15,748,629...15,782,880 		JBrowse link
G FLCN folliculin involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:21258407) UniProt
MGI
TreeGrafter
Ensembl		 PMID:21258407 GO_REF:0000024 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme ISO RGD PMID:15194465 RGD:1582619 NCBI chr 3:53,357,491...53,368,285
Ensembl chr 3:53,358,045...53,365,423 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,144,076...48,155,069
Ensembl chr20:48,150,498...48,157,191 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:26880260 RGD:13504840 NCBI chr28:12,352,658...12,377,960
Ensembl chr28:12,352,659...12,414,579 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G ING2 inhibitor of growth family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,843,478...46,850,856
Ensembl chr16:46,845,289...46,850,637 		JBrowse link
G ITGA8 integrin subunit alpha 8 acts_upstream_of_or_within ISO (PMID:17537792) MGI PMID:17537792 NCBI chr 2:21,034,630...21,244,304
Ensembl chr 2:21,075,653...21,241,951 		JBrowse link
G LOC100687242 heat shock protein HSP 90-beta-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,591,965...7,594,265 JBrowse link
G LOC119877302 syntenin-1 involved_in IEA TreeGrafter GO_REF:0000118
G LRG1 leucine rich alpha-2-glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23868260) Ensembl
MGI		 PMID:23868260 GO_REF:0000107 NCBI chr20:55,177,777...55,180,382
Ensembl chr20:55,177,824...55,180,369 		JBrowse link
G MEN1 menin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,346,747...52,352,884
Ensembl chr18:52,346,933...52,353,340 		JBrowse link
G MIR21 microRNA mir-21 acts_upstream_of ISO (PMID:31611175) ARUK-UCL PMID:31611175 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR30B microRNA mir-30b involved_in ISO (PMID:28977001) BHF-UCL PMID:28977001 NCBI chr13:30,906,038...30,906,097
Ensembl chr13:30,906,038...30,906,097 		JBrowse link
G MYOCD myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327 		JBrowse link
G NPNT nephronectin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17537792) Ensembl
MGI		 PMID:17537792 GO_REF:0000107 NCBI chr32:26,706,147...26,781,792
Ensembl chr32:26,705,476...26,781,275 		JBrowse link
G PTGER1 prostaglandin E receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,156,055...48,159,838
Ensembl chr20:48,157,973...48,159,921 		JBrowse link
G RNF111 ring finger protein 111 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16601693) Ensembl
MGI		 PMID:16601693 GO_REF:0000107 NCBI chr30:23,934,156...24,027,529
Ensembl chr30:23,976,311...24,027,759 		JBrowse link
G SDCBP syndecan binding protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr29:9,331,876...9,370,489 JBrowse link
G SLC2A10 solute carrier family 2 member 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26376865) ARUK-UCL
Ensembl		 PMID:26376865 GO_REF:0000107 NCBI chr24:33,905,099...33,920,604
Ensembl chr24:33,905,203...33,919,454 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SNW1 SNW domain containing 1 involved_in ISO (PMID:11278756) UniProt PMID:11278756 NCBI chr 8:50,478,924...50,512,360
Ensembl chr 8:50,479,338...50,512,243 		JBrowse link
G STK11 serine/threonine kinase 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118 		JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) BHF-UCL PMID:18762808 NCBI chr 6:16,775,438...16,781,695
Ensembl chr 6:16,775,836...16,780,935 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (PMID:25382630) RGD
MGI		 PMID:8106553 PMID:25382630 RGD:1579949 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915 		JBrowse link
G TSC22D1 TSC22 domain family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:6,375,585...6,506,511
Ensembl chr22:6,375,577...6,505,672 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,419,812...46,541,888
Ensembl chr19:46,423,998...46,542,122 		JBrowse link
regulation of activin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15958512) Ensembl
MGI		 PMID:15958512 GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192 		JBrowse link
G MEN1 menin 1 ISO RGD PMID:15031321 RGD:2290185 NCBI chr18:52,346,747...52,352,884
Ensembl chr18:52,346,933...52,353,340 		JBrowse link
regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FSTL1 follistatin like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr33:23,892,317...23,914,406
Ensembl chr33:23,894,573...23,933,779 		JBrowse link
G FSTL3 follistatin like 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
G FSTL4 follistatin like 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:21,453,982...21,850,969
Ensembl chr11:21,458,678...21,856,547 		JBrowse link
G FSTL5 follistatin like 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:57,985,075...58,621,937
Ensembl chr15:57,986,912...58,670,930 		JBrowse link
G HOXA13 homeobox A13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12783783) Ensembl
MGI		 PMID:12783783 GO_REF:0000107 NCBI chr14:40,371,234...40,375,261
Ensembl chr14:40,373,059...40,375,980 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17359964) Ensembl
MGI		 PMID:17359964 GO_REF:0000107 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO (PMID:33667543) UniProt PMID:33667543 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17472960) Ensembl
MGI		 PMID:17472960 GO_REF:0000107 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
G SFRP4 secreted frizzled related protein 4 involved_in ISO (MGI:5790095|PMID:27355534) UniProt PMID:27355534 MGI:5790095 NCBI chr18:12,018,049...12,028,123
Ensembl chr18:12,017,978...12,027,788 		JBrowse link
G TFAP2B transcription factor AP-2 beta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:18,544,176...18,574,300
Ensembl chr12:18,544,446...18,572,902 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
regulation of nodal signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DACT1 dishevelled binding antagonist of beta catenin 1 NOT|involved_in ISO (PMID:17197390)
(MGI:5437437|PMID:17197390)		 UniProt PMID:17197390 MGI:5437437 NCBI chr 8:33,950,016...33,959,671
Ensembl chr 8:33,949,926...33,958,449 		JBrowse link
G DMRT1 doublesex and mab-3 related transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23473982) Ensembl
MGI		 PMID:23473982 GO_REF:0000107 NCBI chr 1:89,677,554...89,790,692
Ensembl chr 1:89,677,533...89,790,145 		JBrowse link
regulation of SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR130A microRNA mir-130a acts_upstream_of_or_within ISO (PMID:23390484) MGI PMID:23390484 NCBI chr18:38,543,618...38,543,679
Ensembl chr18:38,543,618...38,543,681 		JBrowse link
G MIR181C microRNA mir-181c acts_upstream_of_or_within ISO (PMID:23390484) MGI PMID:23390484 NCBI chr20:48,593,343...48,593,403
Ensembl chr20:48,593,325...48,593,421 		JBrowse link
G MIR185 microRNA mir-185 acts_upstream_of_or_within ISO (PMID:23390484) MGI PMID:23390484 NCBI chr26:29,296,014...29,296,069
Ensembl chr26:29,296,004...29,296,079 		JBrowse link
G MIR25 microRNA mir-25 acts_upstream_of_or_within ISO (PMID:23390484) MGI PMID:23390484 NCBI chr 6:9,498,993...9,499,051
Ensembl chr 6:9,498,993...9,499,051 		JBrowse link
G MIR7-1 microRNA mir-7-1 acts_upstream_of_or_within ISO (PMID:23390484) MGI PMID:23390484 NCBI chr 1:75,509,765...75,509,828
Ensembl chr 1:75,509,743...75,509,851 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12543979) Ensembl
MGI		 PMID:12543979 GO_REF:0000107 NCBI chr10:55,429,989...55,571,917
Ensembl chr10:55,429,940...55,571,916 		JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11163184) Ensembl
MGI		 PMID:11163184 GO_REF:0000107 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
Ensembl chr 9:26,736,675...26,740,177 		JBrowse link
regulation of transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL9 BCL9 transcription coactivator NOT|involved_in ISO (PMID:19328798) BHF-UCL PMID:19328798 NCBI chr17:58,105,914...58,189,065
Ensembl chr17:58,168,375...58,189,062 		JBrowse link
G CAV3 caveolin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21182936) Ensembl
MGI		 PMID:21182936 GO_REF:0000107 NCBI chr20:9,384,901...9,398,055
Ensembl chr20:9,384,901...9,401,196 		JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10208746) Ensembl
MGI		 PMID:10208746 GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
G ENG endoglin involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:17376778 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2313627 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G GDF2 growth differentiation factor 2 NOT|involved_in ISO (MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:4830635 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G IL17F interleukin 17F involved_in ISO (PMID:11591732) UniProt PMID:11591732 NCBI chr12:19,904,283...19,908,497
Ensembl chr12:19,904,126...19,908,619 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:40,430,096...40,475,193
Ensembl chr 1:40,260,064...40,457,609 		JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:17,110,620...17,169,826
Ensembl chr25:17,110,637...17,169,291 		JBrowse link
G LOC609612 folate receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:25,944,350...25,951,010 JBrowse link
G LOX lysyl oxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25715398) Ensembl
MGI		 PMID:25715398 GO_REF:0000107 NCBI chr11:12,023,645...12,040,015
Ensembl chr11:12,027,250...12,039,819 		JBrowse link
G NREP neuronal regeneration related protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14985127) Ensembl
MGI
TreeGrafter		 PMID:14985127 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:997,142...1,025,215
Ensembl chr 3:997,234...1,024,087 		JBrowse link
G PALS1 protein associated with LIN7 1, MAGUK p55 family member involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:41,230,230...41,330,017
Ensembl chr 8:41,275,947...41,327,348 		JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11711431) Ensembl
MGI		 PMID:11711431 GO_REF:0000107 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD7 SMAD family member 7 ISO RGD PMID:11959632 RGD:625758 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in IEA Ensembl GO_REF:0000107
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TRIM33 tripartite motif containing 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,117,085...52,230,846
Ensembl chr17:52,118,476...52,230,530 		JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16824956) Ensembl
MGI		 PMID:16824956 GO_REF:0000107 NCBI chr 2:15,300,401...15,481,535
Ensembl chr 2:15,299,723...15,481,495 		JBrowse link
G ZNF703 zinc finger protein 703 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,669,506...27,673,732
Ensembl chr16:27,670,897...27,673,803 		JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:32,048,151...32,157,698
Ensembl chr 7:32,048,183...32,157,146 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAND5 DAN domain BMP antagonist family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151 		JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,311,238...17,551,536
Ensembl chr11:17,311,226...17,551,536 		JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:26,129,528...26,521,782
Ensembl chr17:26,130,781...26,521,779 		JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:29,682,182...29,699,469
Ensembl chr33:29,692,371...29,767,771 		JBrowse link
SMAD protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABTB3 ankyrin repeat and BTB domain containing 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:31,168,809...31,479,343
Ensembl chr10:31,169,868...31,478,420 		JBrowse link
G ACVR2A activin A receptor type 2A ISO RGD PMID:27769861 RGD:329853763 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ATOH8 atonal bHLH transcription factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:39,255,725...39,280,022 JBrowse link
G BECN1 beclin 1 ISO RGD PMID:27769861 RGD:329853763 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in ISO (PMID:20807528) MGI PMID:20807528 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:56,327,104...56,332,608
Ensembl chr  X:56,327,182...56,332,047 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:23,931,360...23,971,516
Ensembl chr 1:23,960,723...23,969,405 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G GDF11 growth differentiation factor 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373 		JBrowse link
G GDF15 growth differentiation factor 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,633,131...44,636,842
Ensembl chr20:44,634,588...44,636,821 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (MGI:5751611|PMID:26774823) UniProt PMID:26774823 MGI:5751611 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:27769861 RGD:329853763 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in ISO (MGI:1353670|PMID:10681527) UniProt PMID:10681527 MGI:1353670 NCBI chr18:17,973,058...19,098,785
Ensembl chr18:17,918,928...18,930,059 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:27769861 RGD:329853763 NCBI chr24:23,672,343...23,673,937
Ensembl chr24:23,633,579...23,673,921 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO RGD PMID:27769861 RGD:329853763 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401 		JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 NOT|involved_in ISO (PMID:16777850) UniProt PMID:16777850 NCBI chr 7:44,436,100...44,583,657
Ensembl chr 7:44,454,095...44,583,657 		JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15356634) Ensembl
MGI		 PMID:15356634 GO_REF:0000107 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G RBPMS RNA binding protein, mRNA processing factor involved_in ISO (PMID:17099224) UniProt PMID:17099224 NCBI chr16:33,788,675...33,961,595
Ensembl chr16:33,788,781...33,960,286 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 acts_upstream_of_or_within ISO (PMID:20660756) MGI PMID:20660756 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G SMAD1 SMAD family member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098 		JBrowse link
G SMAD2 SMAD family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23390484)
(PMID:16806156)		 Ensembl
MGI
TreeGrafter		 PMID:16806156 PMID:23390484 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23390484)
(PMID:30729664)		 Ensembl
MGI
TreeGrafter
BHF-UCL		 PMID:23390484 PMID:30729664 GO_REF:0000107 GO_REF:0000118 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9420335) Ensembl
MGI
TreeGrafter		 PMID:9420335 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD5 SMAD family member 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:24,027,603...24,082,673
Ensembl chr11:24,028,126...24,078,169 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMAD9 SMAD family member 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:3,768,851...3,844,645
Ensembl chr25:3,779,197...3,841,321 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16806156) Ensembl
MGI		 PMID:16806156 GO_REF:0000107 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G WWTR1 WW domain containing transcription regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:44,277,707...44,409,911
Ensembl chr23:44,278,557...44,410,007 		JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:28,807,368...29,035,946
Ensembl chr 4:28,854,908...29,045,986 		JBrowse link
G ZMIZ2 zinc finger MIZ-type containing 2 NOT|involved_in ISO (PMID:16777850) UniProt PMID:16777850
transforming growth factor beta receptor complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1C activin A receptor type 1C ISO TbetaR-II, ActR-II (Chlorocebus aethiops), ligand-dependent RGD PMID:8940033 RGD:631880 NCBI chr36:3,534,231...3,583,310
Ensembl chr36:3,541,248...3,613,384 		JBrowse link
G LOC612523 EP300-interacting inhibitor of differentiation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,712,193...113,713,420 JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO RGD PMID:8106553 RGD:1579949 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
transforming growth factor beta receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11376112) Ensembl
MGI
TreeGrafter		 PMID:11376112 GO_REF:0000107 GO_REF:0000118 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14580334) Ensembl
MGI
TreeGrafter		 PMID:14580334 GO_REF:0000107 GO_REF:0000118 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G ADAM32 ADAM metallopeptidase domain 32 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:26,228,380...26,410,634
Ensembl chr16:26,228,415...26,410,583 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:26,413,345...26,551,293
Ensembl chr16:26,414,583...26,551,122 		JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 acts_upstream_of_or_within ISO PMID:11376112 MGI PMID:11376112 RGD:8554753 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533 		JBrowse link
G APOA1 apolipoprotein A1 NOT|involved_in ISO (PMID:23726972) UniProt PMID:23726972 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,192,261...33,243,034
Ensembl chr10:33,191,602...33,242,669 		JBrowse link
G ARRB2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454 		JBrowse link
G B9D2 B9 domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12208849), (PMID:23868260) RGD
MGI
TreeGrafter		 PMID:12208849 PMID:23868260 PMID:33360052 GO_REF:0000118 RGD:127229954 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:12933693 GO_REF:0000118 RGD:632261 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G CAV2 caveolin 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21832243) Ensembl
MGI		 PMID:21832243 GO_REF:0000107 NCBI chr14:55,437,622...55,445,481
Ensembl chr14:55,437,622...55,445,469 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:14505427 RGD:1582324 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CDH5 cadherin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:82,830,505...82,863,931
Ensembl chr 5:82,830,939...82,863,882 		JBrowse link
G CHST11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16079159) Ensembl
MGI		 PMID:16079159 GO_REF:0000107 NCBI chr10:33,555,629...33,810,808
Ensembl chr10:33,555,628...33,810,558 		JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:56,327,104...56,332,608
Ensembl chr  X:56,327,182...56,332,047 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16619037) Ensembl
MGI		 PMID:16619037 GO_REF:0000107 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995 		JBrowse link
G CLDN5 claudin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:29,702,464...29,704,950
Ensembl chr26:29,703,683...29,704,339 		JBrowse link
G COL1A2 collagen type I alpha 2 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:19,883,731...19,919,527
Ensembl chr14:19,883,868...19,919,527 		JBrowse link
G COL3A1 collagen type III alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:30,488,250...30,526,367
Ensembl chr36:30,488,488...30,536,765 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G DUSP22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (PMID:12138158) MGI PMID:12138158 NCBI chr35:678,320...733,225
Ensembl chr35:678,155...732,397 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:23,931,360...23,971,516
Ensembl chr 1:23,960,723...23,969,405 		JBrowse link
G ENG endoglin NOT|involved_in ISO
IBA
IEA		 (PMID:18223685) BHF-UCL
GO_Central
TreeGrafter
Ensembl		 PMID:18223685 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within ISO (PMID:28106121) MGI PMID:28106121 NCBI chr 8:28,864,642...28,913,864
Ensembl chr 8:28,864,925...28,914,368 		JBrowse link
G FERMT2 FERM domain containing kindlin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:29,083,538...29,135,915
Ensembl chr 8:29,084,531...29,133,391 		JBrowse link
G FLCN folliculin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21258407) Ensembl
MGI		 PMID:21258407 GO_REF:0000107 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G FOXH1 forkhead box H1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:37,883,554...37,887,324
Ensembl chr13:37,882,687...37,885,319 		JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in ISO (PMID:14557487) BHF-UCL PMID:14557487 NCBI chr21:50,279,320...50,282,843
Ensembl chr21:50,280,208...50,282,680 		JBrowse link
G FUT8 fucosyltransferase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16236725) Ensembl
MGI		 PMID:16236725 GO_REF:0000107 NCBI chr 8:39,670,629...39,972,729
Ensembl chr 8:39,825,246...39,972,612 		JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr35:10,304,741...10,387,746
Ensembl chr35:10,305,350...10,385,672 		JBrowse link
G GLG1 golgi glycoprotein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:20530870) Ensembl
MGI		 PMID:20530870 GO_REF:0000107 NCBI chr 5:76,020,743...76,171,477
Ensembl chr 5:76,020,084...76,167,007 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17159989) Ensembl
MGI		 PMID:17159989 GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr25:24,964,908...24,993,276
Ensembl chr25:24,964,908...24,993,297 		JBrowse link
G ITGA8 integrin subunit alpha 8 acts_upstream_of ISO (PMID:17537792) MGI PMID:17537792 NCBI chr 2:21,034,630...21,244,304
Ensembl chr 2:21,075,653...21,241,951 		JBrowse link
G ITGB1 integrin subunit beta 1 NOT|involved_in ISO (PMID:24036928)
(MGI:5582864|PMID:24036928)		 UniProt PMID:24036928 MGI:5582864 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961 		JBrowse link
G ITGB5 integrin subunit beta 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:27,797,204...27,912,558
Ensembl chr33:27,797,667...27,912,584 		JBrowse link
G ITGB6 integrin subunit beta 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30952606)
(PMID:12634787)		 Ensembl
MGI		 PMID:12634787 PMID:30952606 GO_REF:0000107 NCBI chr36:5,833,206...5,962,699
Ensembl chr36:5,834,638...5,962,633 		JBrowse link
G ITGB8 integrin subunit beta 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30952606) Ensembl
MGI		 PMID:30952606 GO_REF:0000107 NCBI chr14:34,370,957...34,449,091
Ensembl chr14:34,349,232...34,444,235 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G LGALS9 galectin 9 involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
G LRRC32 leucine rich repeat containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:22,051,140...22,059,714
Ensembl chr21:22,051,920...22,057,632 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12379497)
(PMID:7730318)		 Ensembl
MGI		 PMID:7730318 PMID:12379497 GO_REF:0000107 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433 		JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12208849) Ensembl
MGI		 PMID:12208849 GO_REF:0000107 NCBI chr 1:113,124,109...113,152,283
Ensembl chr 1:113,124,109...113,150,442 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (PMID:12941696) MGI PMID:12941696 NCBI chr 2:43,918,210...43,996,817
Ensembl chr 2:43,917,604...43,995,209 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:16145668) MGI PMID:16145668 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MIR143 microRNA mir-143 acts_upstream_of_or_within ISO (PMID:29925839) MGI PMID:29925839 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594 		JBrowse link
G MIR145 microRNA mir-145 acts_upstream_of_or_within ISO (PMID:29925839) MGI PMID:29925839 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210 		JBrowse link
G MIR183 microRNA mir-183 involved_in ISO (PMID:24586048) ARUK-UCL PMID:24586048 NCBI chr14:7,068,542...7,068,603
Ensembl chr14:7,068,519...7,068,625 		JBrowse link
G MIR212 microRNA mir-212 involved_in ISO (PMID:25217442) BHF-UCL PMID:25217442 NCBI chr 9:46,153,913...46,153,974
Ensembl chr 9:46,153,903...46,153,984 		JBrowse link
G MIR26A-1 microRNA mir-26a-1 involved_in ISO (PMID:20857419) BHF-UCL PMID:20857419 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140 		JBrowse link
G MIR26A-2 microRNA mir-26a-2 involved_in ISO (PMID:20857419) BHF-UCL PMID:20857419 NCBI chr10:1,880,513...1,880,572
Ensembl chr10:1,880,513...1,880,572 		JBrowse link
G MIR30A microRNA mir-30a involved_in ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr12:33,783,894...33,783,956
Ensembl chr12:33,783,891...33,783,961 		JBrowse link
G MSTN myostatin acts_upstream_of_or_within ISO (PMID:12595574) MGI PMID:12595574 NCBI chr37:729,172...734,255
Ensembl chr37:729,172...734,362 		JBrowse link
G NDP norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:29715368) MGI PMID:29715368 NCBI chr  X:37,949,560...37,975,573
Ensembl chr  X:37,950,489...37,975,346 		JBrowse link
G NLK nemo like kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,399,930...42,557,065
Ensembl chr 9:42,400,219...42,556,904 		JBrowse link
G NODAL nodal growth differentiation factor acts_upstream_of_or_within ISO (PMID:14511481) MGI PMID:14511481 NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151 		JBrowse link
G NPNT nephronectin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17537792) Ensembl
MGI		 PMID:17537792 GO_REF:0000107 NCBI chr32:26,706,147...26,781,792
Ensembl chr32:26,705,476...26,781,275 		JBrowse link
G NRROS negative regulator of reactive oxygen species involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:29,682,182...29,699,469
Ensembl chr33:29,692,371...29,767,771 		JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16103213) Ensembl
MGI		 PMID:16103213 GO_REF:0000107 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497 		JBrowse link
G ONECUT2 one cut homeobox 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16103213) Ensembl
MGI		 PMID:16103213 GO_REF:0000107 NCBI chr 1:18,428,112...18,486,047
Ensembl chr 1:18,440,172...18,486,048 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO PMID:22073128 BHF-UCL PMID:22073128 RGD:8554355 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PIAS2 protein inhibitor of activated STAT 2 NOT|involved_in ISO (PMID:16777850) UniProt PMID:16777850 NCBI chr 7:44,436,100...44,583,657
Ensembl chr 7:44,454,095...44,583,657 		JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15356634) Ensembl
MGI		 PMID:15356634 GO_REF:0000107 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (PMID:24036928) UniProt PMID:24036928 NCBI chr13:35,302,439...35,541,336
Ensembl chr13:35,303,380...35,541,294 		JBrowse link
G PTPRK protein tyrosine phosphatase receptor type K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:66,596,659...67,022,631
Ensembl chr 1:66,597,563...67,124,540 		JBrowse link
G PXN paxillin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:16,157,231...16,224,028
Ensembl chr26:16,159,025...16,184,820 		JBrowse link
G SELENON selenoprotein N acts_upstream_of_or_within ISO (PMID:28106121) MGI PMID:28106121 NCBI chr 2:74,134,448...74,149,585 JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18212064) Ensembl
MGI		 PMID:18212064 GO_REF:0000107 NCBI chr34:34,871,770...34,898,681
Ensembl chr34:34,871,574...34,894,854 		JBrowse link
G SMAD1 SMAD family member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098 		JBrowse link
G SMAD2 SMAD family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18212064)
(PMID:11557747), (PMID:14749725)		 Ensembl
MGI
TreeGrafter		 PMID:11557747 PMID:14749725 PMID:18212064 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15239668), (PMID:16619037), (PMID:21937600)
TGFbeta-1 dependent, in pancreatic stellate cells		 RGD
MGI
TreeGrafter
Ensembl		 PMID:15239668 PMID:16371439 PMID:16619037 PMID:16891311 PMID:21937600 GO_REF:0000107 GO_REF:0000118 RGD:1625706 RGD:2300404 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18212064) Ensembl
MGI
TreeGrafter		 PMID:18212064 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD5 SMAD family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11376112) Ensembl
MGI
TreeGrafter		 PMID:11376112 GO_REF:0000107 GO_REF:0000118 NCBI chr11:24,027,603...24,082,673
Ensembl chr11:24,028,126...24,078,169 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11557747) Ensembl
MGI
TreeGrafter		 PMID:11557747 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMAD9 SMAD family member 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:3,768,851...3,844,645
Ensembl chr25:3,779,197...3,841,321 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (MGI:6453080|PMID:31314592) ARUK-UCL PMID:31314592 MGI:6453080 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12464436) Ensembl
MGI		 PMID:12464436 GO_REF:0000107 NCBI chr10:25,623,381...25,657,630
Ensembl chr10:25,623,940...25,657,543 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in ISS
IEA
IBA		 AgBase
Ensembl
GO_Central
TreeGrafter		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
G TGFB3 transforming growth factor beta 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:48,920,874...48,946,037
Ensembl chr 8:48,923,423...48,945,816 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17078885)
(PMID:14580334), (PMID:15820682)
(PMID:21832243)
(PMID:11285230)		 RGD
MGI
TreeGrafter
Ensembl		 PMID:8272871 PMID:11285230 PMID:14580334 PMID:15820682 PMID:17078885 More... GO_REF:0000107 GO_REF:0000118 RGD:2302021 RGD:2302517 RGD:737663 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21420963) RGD
MGI
TreeGrafter
Ensembl		 PMID:18684975 PMID:21420963 GO_REF:0000107 GO_REF:0000118 RGD:2302517 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:25382630) Ensembl
MGI
TreeGrafter		 PMID:25382630 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO (PMID:28811219) MGI PMID:28811219 NCBI chr 9:3,018,599...3,122,664
Ensembl chr 9:3,020,533...3,171,471 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18212064) Ensembl
MGI		 PMID:18212064 GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,510,759...5,634,954
Ensembl chr10:5,510,022...5,634,202 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:19135894) UniProt PMID:19135894 NCBI chr  X:35,522,873...35,676,086 JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:39,934,105...39,937,666
Ensembl chr 6:39,934,068...39,936,628 		JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12595574) Ensembl
MGI
TreeGrafter		 PMID:12595574 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:26,711,470...26,717,625
Ensembl chr 9:26,711,959...26,716,348 		JBrowse link
G ZFYVE9 zinc finger FYVE-type containing 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:9,014,092...9,198,178
Ensembl chr15:9,015,863...9,289,929 		JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:28,807,368...29,035,946
Ensembl chr 4:28,854,908...29,045,986 		JBrowse link
G ZMIZ2 zinc finger MIZ-type containing 2 NOT|involved_in ISO (PMID:16777850) UniProt PMID:16777850
G ZYX zyxin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:6,304,163...6,313,923 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      signal transduction 6326
        cell surface receptor signaling pathway 2805
          enzyme-linked receptor protein signaling pathway 1041
            cell surface receptor protein serine/threonine kinase signaling pathway 435
              SMAD protein signal transduction + 108
              anti-Mullerian hormone receptor signaling pathway + 2
              negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway + 187
              positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway + 115
              regulation of transmembrane receptor protein serine/threonine kinase signaling pathway + 312
              transforming growth factor beta receptor superfamily signaling pathway + 405
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        signaling 6873
          signal transduction 6326
            cell surface receptor signaling pathway 2805
              enzyme-linked receptor protein signaling pathway 1041
                cell surface receptor protein serine/threonine kinase signaling pathway 435
                  SMAD protein signal transduction + 108
                  anti-Mullerian hormone receptor signaling pathway + 2
                  negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway + 187
                  positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway + 115
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway + 312
                  transforming growth factor beta receptor superfamily signaling pathway + 405
paths to the root