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ONTOLOGY REPORT - ANNOTATIONS

Term:centriole replication
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Accession:GO:0007099 term browser browse the term
Definition:The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
Synonyms:exact_synonym: centriole duplication
 broad_synonym: microtubule basal body duplication
 related_synonym: ciliary basal body duplication
 alt_id: GO:0032054


show annotations for term's descendants           Sort by:
 
centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc57 coiled-coil domain containing 57 involved_in ISO
IBA		 (PMID:32402286)
PMID:21873635		 RGD PMID:32402286 PMID:21873635 RGD:13792537 NCBI chr10:106,092,784...106,196,405
Ensembl chr10:106,092,947...106,196,077 		JBrowse link
G Ccp110 centriolar coiled-coil protein 110 involved_in ISO
IBA		 (PMID:16244668), (PMID:17681131)
PMID:21873635		 RGD PMID:16244668 PMID:17681131 PMID:21873635 RGD:13792537 NCBI chr 1:173,042,238...173,072,873
Ensembl chr 1:173,042,310...173,072,873 		JBrowse link
G Cdk2 cyclin dependent kinase 2 involved_in ISO (PMID:26297806) RGD PMID:26297806 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISO
IEA		 (PMID:26297806)
GO_REF:0000107		 RGD
Ensembl		 PMID:26297806 GO_REF:0000107 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Cenpj centromere protein J involved_in
acts_upstream_of_or_within		 ISO (PMID:17681131), (PMID:22020124)
MGI:2448985|MGI:4432238 (MGI:5563859|PMID:24706806)		 RGD PMID:17681131 PMID:22020124 PMID:24706806 MGI:5563859 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cep135 centrosomal protein 135 involved_in ISO
IBA		 (PMID:17681131)
PMID:21873635		 RGD PMID:17681131 PMID:21873635 RGD:13792537 NCBI chr14:31,530,538...31,595,718
Ensembl chr14:31,531,482...31,595,772 		JBrowse link
G Cep152 centrosomal protein 152 involved_in ISO (MGI:5527201|PMID:24240477)
(PMID:21059844)		 RGD PMID:21059844 PMID:24240477 MGI:5527201 NCBI chr 3:112,803,185...112,878,298
Ensembl chr 3:112,810,425...112,878,458 		JBrowse link
G Cep192 centrosomal protein 192 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:61,346,957...61,458,405
Ensembl chr18:61,332,158...61,458,379 		JBrowse link
G Cep295 centrosomal protein 295 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32060285)		 UniProt
RGD		 PMID:32060285 GO_REF:0000024 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552 		JBrowse link
G Cep44 centrosomal protein 44 involved_in ISO
ISS		 (PMID:32060285)
GO_REF:0000024		 RGD
UniProt		 PMID:32060285 GO_REF:0000024 NCBI chr16:33,711,548...33,733,226
Ensembl chr16:33,711,559...33,733,225 		JBrowse link
G Cep63 centrosomal protein 63 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO
ISS		 PMID:21873635
GO_REF:0000107
MGI:4377328 (MGI:5662131|PMID:26158450)
(MGI:5527201|PMID:24240477)
(PMID:26297806)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24240477 PMID:26158450 PMID:26297806 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5527201 MGI:5662131, RGD:13792537 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Cep72 centrosomal protein 72 involved_in ISO
IBA		 (PMID:26297806)
PMID:21873635		 RGD PMID:26297806 PMID:21873635 RGD:13792537 NCBI chr 1:29,225,312...29,255,294
Ensembl chr 1:29,225,361...29,255,271 		JBrowse link
G Cetn1 centrin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:651,591...652,293
Ensembl chr18:651,591...652,293 		JBrowse link
G Cetn2 centrin 2 involved_in ISO
IBA		 (PMID:12176356)
PMID:21873635		 RGD PMID:12176356 PMID:21873635 RGD:13792537 NCBI chr  X:150,769,944...150,775,052
Ensembl chr  X:150,769,953...150,774,919 		JBrowse link
G Cetn4 centrin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:120,199,951...120,203,311
Ensembl chr 2:120,199,942...120,203,348 		JBrowse link
G Cntrob centrobin, centriole duplication and spindle assembly protein involved_in IBA
ISO		 PMID:21873635
(PMID:16275750), (PMID:21576394)		 RGD PMID:16275750 PMID:21576394 PMID:21873635 RGD:13792537 NCBI chr10:54,022,523...54,047,793
Ensembl chr10:54,022,852...54,044,849 		JBrowse link
G Deup1 deuterosome assembly protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199 		JBrowse link
G Ofd1 Ofd1 centriole and centriolar satellite protein NOT|involved_in ISO (MGI:4457459|PMID:20230748) RGD PMID:20230748 MGI:4457459 NCBI chr  X:28,015,347...28,056,115
Ensembl chr  X:28,015,347...28,056,110 		JBrowse link
G Plk4 polo-like kinase 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21059844), (PMID:21725316), (PMID:22020124), (PMID:30804208)
(MGI:5527201|PMID:24240477)
GO_REF:0000002		 UniProt
RGD
InterPro		 PMID:21059844 PMID:21725316 PMID:22020124 PMID:24240477 PMID:30804208 GO_REF:0000002 GO_REF:0000024 MGI:5527201 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Poc1b POC1 centriolar protein B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:32060285)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:32060285 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:33,924,035...34,025,908
Ensembl chr 7:33,924,189...34,025,903 		JBrowse link
G RGD1304728 similar to 4933427D14Rik protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:56,783,869...56,832,668
Ensembl chr10:56,783,775...56,832,968 		JBrowse link
G Rttn rotatin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:82,220,999...82,398,334
Ensembl chr18:82,221,050...82,398,333 		JBrowse link
G Sass6 SAS-6 centriolar assembly protein involved_in ISO
IBA		 (PMID:16244668), (PMID:17681131), (PMID:22020124)
PMID:21873635		 RGD PMID:16244668 PMID:17681131 PMID:22020124 PMID:21873635 RGD:13792537 NCBI chr 2:204,546,660...204,578,930
Ensembl chr 2:204,546,660...204,578,927 		JBrowse link
G Wdr62 WD repeat domain 62 involved_in ISO
IBA		 (PMID:26297806)
PMID:21873635		 RGD PMID:26297806 PMID:21873635 RGD:13792537 NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637 		JBrowse link
centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd3 C2 domain containing 3 centriole elongation regulator involved_in ISO
IBA		 (PMID:24997988)
PMID:21873635
(MGI:5585526|PMID:24997988)		 RGD PMID:24997988 PMID:21873635 MGI:5585526, RGD:13792537 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520 		JBrowse link
G Cenpj centromere protein J involved_in ISO
IBA		 (PMID:22020124)
PMID:21873635		 RGD PMID:22020124 PMID:21873635 RGD:13792537 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
negative regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccp110 centriolar coiled-coil protein 110 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:173,042,238...173,072,873
Ensembl chr 1:173,042,310...173,072,873 		JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452 		JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4830038|PMID:20627074)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20627074 GO_REF:0000024 GO_REF:0000107 MGI:4830038 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISS
ISO		 GO_REF:0000002
GO_REF:0000024
(PMID:26337392)		 InterPro
UniProt
RGD		 PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034 		JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA		 (PMID:23769972)
PMID:21873635		 RGD PMID:23769972 PMID:21873635 RGD:13792537 NCBI chr10:71,943,384...72,075,567
Ensembl chr10:71,943,375...72,075,558 		JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:27185865) RGD PMID:27185865 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO
IBA		 (PMID:27185865)
PMID:21873635		 RGD PMID:27185865 PMID:21873635 RGD:13792537 NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964 		JBrowse link
G Cep295 centrosomal protein 295 involved_in ISO
ISS		 (PMID:27185865)
GO_REF:0000024		 RGD
UniProt		 PMID:27185865 GO_REF:0000024 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552 		JBrowse link
G Ppp1r35 protein phosphatase 1, regulatory subunit 35 involved_in ISO (PMID:30168418) RGD PMID:30168418 NCBI chr12:18,915,909...18,919,253 JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229 		JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Plk4 polo-like kinase 4 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:22349705)
(PMID:16244668), (PMID:17681131), (PMID:27796307)		 UniProt
RGD		 PMID:16244668 PMID:17681131 PMID:22349705 PMID:27796307 GO_REF:0000024 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Sass6 SAS-6 centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 2:204,546,660...204,578,930
Ensembl chr 2:204,546,660...204,578,927 		JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005 		JBrowse link
G Cenpj centromere protein J involved_in ISO (PMID:20531387) RGD PMID:20531387 NCBI chr15:30,626,946...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cep295 centrosomal protein 295 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552 		JBrowse link
G Cep295nl CEP295 N-terminal like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,562,190...103,581,183
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Cep76 centrosomal protein 76 involved_in ISO
IBA		 (PMID:19460342)
PMID:21873635		 RGD PMID:19460342 PMID:21873635 RGD:13792537 NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504 		JBrowse link
G LOC100302465 hypothetical LOC100302465 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:189,059,744...189,293,353
Ensembl chr 1:189,059,746...189,293,435 		JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:20352051)
GO_REF:0000024		 RGD
UniProt		 PMID:20352051 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Plk2 polo-like kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15242618), (PMID:19001868), (PMID:20352051), (PMID:20531387)		 UniProt
RGD		 PMID:15242618 PMID:19001868 PMID:20352051 PMID:20531387 GO_REF:0000024 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Spice1 spindle and centriole associated protein 1 involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:20736305)		 UniProt
RGD		 PMID:20736305 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:56,289,291...56,332,382
Ensembl chr11:56,290,540...56,332,447 		JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    cellular process 18695
      cell cycle process 1246
        centriole replication 43
          centriole elongation + 8
          negative regulation of centriole replication 6
          positive regulation of centriole replication + 9
          regulation of centriole replication + 22
Path 2
Term Annotations click to browse term
  biological_process 20099
    cellular process 18695
      cellular component organization or biogenesis 6763
        cellular component organization 6510
          organelle organization 3663
            cytoskeleton organization 1540
              microtubule cytoskeleton organization 664
                microtubule organizing center organization 154
                  centrosome cycle 140
                    centrosome duplication 79
                      centriole replication 43
                        centriole elongation + 8
                        negative regulation of centriole replication 6
                        positive regulation of centriole replication + 9
                        regulation of centriole replication + 22
paths to the root