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ONTOLOGY REPORT - ANNOTATIONS


Term:centriole replication
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Accession:GO:0007099 term browser browse the term
Definition:The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
Synonyms:exact_synonym: centriole duplication
 broad_synonym: microtubule basal body duplication
 related_synonym: ciliary basal body duplication
 alt_id: GO:0032054


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centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc57 coiled-coil domain containing 57 involved_in ISO (PMID:32402286) RGD PMID:32402286 NCBI chr10:110,046,012...110,110,775
Ensembl chr10:110,008,603...110,101,872
JBrowse link
G Ccp110 centriolar coiled-coil protein 110 involved_in ISO
IBA
(PMID:16244668), (PMID:17681131)
PMID:21873635
RGD PMID:16244668 PMID:17681131, PMID:21873635 RGD:13792537 NCBI chr 1:188,417,012...188,444,991
Ensembl chr 1:188,420,461...188,444,991
JBrowse link
G Cdk2 cyclin dependent kinase 2 involved_in ISO (PMID:26297806) RGD PMID:26297806 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISO
IEA
(PMID:26297806)
GO_REF:0000107
RGD
Ensembl
PMID:26297806 GO_REF:0000107 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Cenpj centromere protein J involved_in
acts_upstream_of_or_within
ISO (PMID:17681131), (PMID:22020124)
MGI:2448985|MGI:4432238 (MGI:5563859|PMID:24706806)
RGD PMID:17681131 PMID:22020124 PMID:24706806 MGI:5563859 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep135 centrosomal protein 135 involved_in ISO (PMID:17681131) RGD PMID:17681131 NCBI chr14:34,052,168...34,115,763
Ensembl chr14:34,051,003...34,115,273
JBrowse link
G Cep152 centrosomal protein 152 involved_in ISO (MGI:5527201|PMID:24240477) RGD PMID:24240477 MGI:5527201 NCBI chr 3:117,822,799...117,894,856
Ensembl chr 3:117,811,504...117,819,053
JBrowse link
G Cep192 centrosomal protein 192 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:63,572,084...63,656,302
Ensembl chr18:63,524,452...63,656,286
JBrowse link
G Cep295 centrosomal protein 295 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:32060285)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:32060285 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Cep44 centrosomal protein 44 involved_in ISO
ISS
(PMID:32060285)
GO_REF:0000024
RGD
UniProt
PMID:32060285 GO_REF:0000024 NCBI chr16:37,177,379...37,199,043
Ensembl chr16:37,177,443...37,196,784
JBrowse link
G Cep63 centrosomal protein 63 involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
MGI:4377328 (MGI:5662131|PMID:26158450)
(MGI:5527201|PMID:24240477)
(PMID:26297806)
GO_REF:0000024
RGD
UniProt
PMID:24240477 PMID:26158450 PMID:26297806, PMID:21873635 GO_REF:0000024 MGI:5527201 MGI:5662131, RGD:13792537 NCBI chr 8:111,063,988...111,116,014
Ensembl chr 8:111,064,049...111,116,014
JBrowse link
G Cep72 centrosomal protein 72 involved_in ISO (PMID:26297806) RGD PMID:26297806 NCBI chr 1:31,834,977...31,864,938
Ensembl chr 1:31,835,000...31,864,628
JBrowse link
G Cetn1 centrin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:785,972...786,674
Ensembl chr18:785,972...786,674
JBrowse link
G Cetn2 centrin 2 involved_in ISO
IBA
(PMID:12176356)
PMID:21873635
RGD PMID:12176356, PMID:21873635 RGD:13792537 NCBI chr  X:152,927,852...152,933,095
Ensembl chr  X:152,927,718...152,932,953
JBrowse link
G Cetn4 centrin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:124,045,092...124,048,441
Ensembl chr 2:124,045,546...124,047,044
JBrowse link
G Cntrob centrobin, centriole duplication and spindle assembly protein involved_in IBA
ISO
PMID:21873635
(PMID:16275750), (PMID:21576394)
RGD PMID:16275750 PMID:21576394, PMID:21873635 RGD:13792537 NCBI chr10:55,901,929...55,927,121
Ensembl chr10:55,901,901...55,924,158
JBrowse link
G Deup1 deuterosome assembly protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:14,094,742...14,157,232
Ensembl chr 8:14,094,732...14,157,141
JBrowse link
G Ofd1 OFD1, centriole and centriolar satellite protein NOT|involved_in ISO (MGI:4457459|PMID:20230748) RGD PMID:20230748 MGI:4457459 NCBI chr  X:29,562,165...29,602,934
Ensembl chr  X:29,562,165...29,602,925
JBrowse link
G Plk4 polo-like kinase 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5527201|PMID:24240477)
GO_REF:0000002
(PMID:21725316), (PMID:22020124), (PMID:30804208)
UniProt
RGD
InterPro
PMID:21725316 PMID:22020124 PMID:24240477 PMID:30804208 GO_REF:0000002 GO_REF:0000024 MGI:5527201 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
G Poc1b POC1 centriolar protein B involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:32060285)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:32060285 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:41,304,119...41,404,360
Ensembl chr 7:41,304,440...41,404,370
JBrowse link
G RGD1304728 similar to 4933427D14Rik protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:58,726,721...58,776,718
Ensembl chr10:58,729,306...58,771,908
JBrowse link
G Rttn rotatin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:86,071,884...86,247,486
Ensembl chr18:86,071,662...86,247,486
JBrowse link
G Sass6 SAS-6 centriolar assembly protein involved_in ISO (PMID:16244668), (PMID:17681131), (PMID:22020124) RGD PMID:16244668 PMID:17681131 PMID:22020124 NCBI chr 2:219,626,851...219,660,975
Ensembl chr 2:219,628,695...219,652,968
JBrowse link
G Wdr62 WD repeat domain 62 involved_in ISO (PMID:26297806) RGD PMID:26297806 NCBI chr 1:90,995,545...91,034,592
Ensembl chr 1:88,694,824...88,734,223
JBrowse link
centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2cd3 C2 domain containing 3 centriole elongation regulator involved_in ISO
IBA
(PMID:24997988)
PMID:21873635
(MGI:5585526|PMID:24997988)
RGD PMID:24997988, PMID:21873635 MGI:5585526, RGD:13792537 NCBI chr 1:165,382,279...165,480,088
Ensembl chr 1:165,382,690...165,479,655
JBrowse link
G Cenpj centromere protein J involved_in ISO
IBA
(PMID:22020124)
PMID:21873635
RGD PMID:22020124, PMID:21873635 RGD:13792537 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
negative regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccp110 centriolar coiled-coil protein 110 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:188,417,012...188,444,991
Ensembl chr 1:188,420,461...188,444,991
JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707
JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4830038|PMID:20627074)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20627074 GO_REF:0000024 GO_REF:0000107 MGI:4830038 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISO
ISS
GO_REF:0000002
(PMID:26337392)
GO_REF:0000024
InterPro
RGD
UniProt
PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:61,165,652...61,200,865
Ensembl chr 7:61,165,640...61,200,879
JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:220,048,740...220,067,124
Ensembl chr 1:220,048,873...220,067,124
JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA
(PMID:23769972)
PMID:21873635
RGD PMID:23769972, PMID:21873635 RGD:13792537 NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493
JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:27185865) RGD PMID:27185865 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO
IBA
(PMID:27185865)
PMID:21873635
RGD PMID:27185865, PMID:21873635 RGD:13792537 NCBI chr18:48,658,495...48,720,570
Ensembl chr18:48,658,495...48,720,472
JBrowse link
G Cep295 centrosomal protein 295 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:27185865)
Ensembl
UniProt
RGD
PMID:27185865 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:100,811,140...100,827,119
Ensembl chr 1:100,811,755...100,827,111
JBrowse link
G Plk4 polo-like kinase 4 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:22349705)
(PMID:16244668), (PMID:17681131), (PMID:27796307)
UniProt
RGD
PMID:16244668 PMID:17681131 PMID:22349705 PMID:27796307 GO_REF:0000024 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
JBrowse link
G Cenpj centromere protein J involved_in ISO (PMID:20531387) RGD PMID:20531387 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep295 centrosomal protein 295 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Cep295nl CEP295 N-terminal like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:107,363,511...107,381,280
Ensembl chr10:107,363,511...107,376,645
JBrowse link
G Cep76 centrosomal protein 76 involved_in ISO (PMID:19460342) RGD PMID:19460342 NCBI chr18:63,364,990...63,394,766
Ensembl chr18:63,359,832...63,394,766
JBrowse link
G LOC100302465 hypothetical LOC100302465 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:206,324,763...206,417,143
Ensembl chr 1:206,324,765...206,417,143
JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO
ISS
(PMID:20352051)
GO_REF:0000024
RGD
UniProt
PMID:20352051 GO_REF:0000024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Plk2 polo-like kinase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15242618), (PMID:19001868), (PMID:20352051), (PMID:20531387)
UniProt
RGD
PMID:15242618 PMID:19001868 PMID:20352051 PMID:20531387 GO_REF:0000024 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Spice1 spindle and centriole associated protein 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:20736305)
UniProt
RGD
PMID:20736305, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:61,250,649...61,294,116
Ensembl chr11:61,251,696...61,294,022
JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:133,819,302...133,851,362
Ensembl chr 5:133,819,726...133,851,416
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cell cycle process 1174
        centriole replication 42
          centriole elongation + 7
          negative regulation of centriole replication 6
          positive regulation of centriole replication + 6
          regulation of centriole replication + 20
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          organelle organization 4060
            cytoskeleton organization 1453
              microtubule cytoskeleton organization 639
                microtubule organizing center organization 150
                  centrosome cycle 137
                    centrosome duplication 80
                      centriole replication 42
                        centriole elongation + 7
                        negative regulation of centriole replication 6
                        positive regulation of centriole replication + 6
                        regulation of centriole replication + 20
paths to the root