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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic metaphase chromosome alignment
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Accession:GO:0007080 term browser browse the term
Definition:A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.

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mitotic metaphase chromosome alignment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd53 ankyrin repeat domain 53 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624762:2,425,805...2,433,081
Ensembl chrNW_004624762:2,426,614...2,432,752 		JBrowse link
G Becn1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248) UniProt PMID:17938248 NCBI chrNW_004624733:16,459,383...16,469,343 JBrowse link
G Ccdc66 coiled-coil domain containing 66 involved_in ISO (PMID:35849559) UniProt PMID:35849559 NCBI chrNW_004624822:625,327...658,528
Ensembl chrNW_004624822:617,862...655,803 		JBrowse link
G Cdc23 cell division cycle 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624743:31,012,262...31,036,639
Ensembl chrNW_004624743:31,012,720...31,036,762 		JBrowse link
G Cdca5 cell division cycle associated 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624767:21,321,286...21,327,780 JBrowse link
G Cdca8 cell division cycle associated 8 involved_in ISO (PMID:15260989) UniProt PMID:15260989 NCBI chrNW_004624764:20,418,342...20,433,763
Ensembl chrNW_004624764:20,418,585...20,434,026 		JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:15843429) UniProt PMID:15843429 NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076 		JBrowse link
G Cep55 centrosomal protein 55 NOT|involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624737:4,718,904...4,741,317
Ensembl chrNW_004624737:4,718,883...4,740,489 		JBrowse link
G Chmp1a charged multivesicular body protein 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:302,344...309,117
Ensembl chrNW_004624746:302,404...309,644 		JBrowse link
G Chmp1b charged multivesicular body protein 1B involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624770:19,487,040...19,489,740 JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624832:45,293...48,314 JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624789:3,557,811...3,587,814
Ensembl chrNW_004624789:3,557,797...3,587,703 		JBrowse link
G Chmp3 charged multivesicular body protein 3 NOT|involved_in ISO (PMID:20616062) UniProt
ComplexPortal		 PMID:20616062 NCBI chrNW_004624749:16,738,538...16,772,553
Ensembl chrNW_004624749:16,738,416...16,772,391 		JBrowse link
G Chmp4a charged multivesicular body protein 4A involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624820:8,281,081...8,284,969 JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624842:5,454,616...5,505,454
Ensembl chrNW_004624842:5,450,900...5,505,418 		JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in ISO (PMID:20616062) ComplexPortal PMID:20616062 NCBI chrNW_004624744:9,735,585...9,769,635
Ensembl chrNW_004624744:9,739,651...9,769,615 		JBrowse link
G Chmp5 charged multivesicular body protein 5 involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624736:38,025,247...38,044,808 JBrowse link
G Chmp6 charged multivesicular body protein 6 involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624801:10,063,284...10,070,322
Ensembl chrNW_004624801:10,063,614...10,070,320 		JBrowse link
G Chmp7 charged multivesicular body protein 7 involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624758:18,524,338...18,538,909
Ensembl chrNW_004624758:18,524,290...18,538,083 		JBrowse link
G Cul3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:767,347...854,065
Ensembl chrNW_004624823:766,780...852,727 		JBrowse link
G Dctn2 dynactin subunit 2 involved_in ISO (PMID:8647893) UniProt PMID:8647893 NCBI chrNW_004624802:10,412,466...10,429,354 JBrowse link
G Eml3 EMAP like 3 involved_in ISO (PMID:18445686), (PMID:30723163) UniProt PMID:18445686 PMID:30723163 NCBI chrNW_004624926:1,133,177...1,140,440
Ensembl chrNW_004624926:1,133,301...1,140,149 		JBrowse link
G Eml4 EMAP like 4 involved_in ISO (PMID:25789526) UniProt PMID:25789526 NCBI chrNW_004624738:23,887,822...24,045,864
Ensembl chrNW_004624738:23,887,782...24,048,204 		JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:15843429) UniProt PMID:15843429 NCBI chrNW_004624807:10,093,518...10,144,484
Ensembl chrNW_004624807:10,092,934...10,143,399 		JBrowse link
G Kif18a kinesin family member 18A involved_in
acts_upstream_of_or_within 		ISO (PMID:17346968)
(PMID:20981276) 		UniProt
MGI		 PMID:17346968 PMID:20981276 NCBI chrNW_004624766:17,565,072...17,622,342
Ensembl chrNW_004624766:17,564,560...17,622,932 		JBrowse link
G Kif22 kinesin family member 22 involved_in ISO (PMID:15843429) UniProt PMID:15843429 NCBI chrNW_004624782:13,400,119...13,413,074
Ensembl chrNW_004624782:13,399,567...13,412,936 		JBrowse link
G Kif2c kinesin family member 2C involved_in ISO (PMID:15843429) UniProt PMID:15843429 NCBI chrNW_004624906:633,635...660,149
Ensembl chrNW_004624906:633,754...660,254 		JBrowse link
G Kifc1 kinesin family member C1 involved_in ISO (PMID:15843429) UniProt PMID:15843429 NCBI chrNW_004624754:23,405,951...23,421,696
Ensembl chrNW_004624754:23,410,007...23,413,902 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:4,372,014...4,403,061
Ensembl chrNW_004624795:4,371,749...4,403,217 		JBrowse link
G Nudc nuclear distribution C, dynein complex regulator involved_in ISO (PMID:25789526) UniProt PMID:25789526 NCBI chrNW_004624764:10,889,020...10,925,547
Ensembl chrNW_004624764:10,908,956...10,925,547 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) UniProt PMID:24107630 NCBI chrNW_004624832:4,404,367...4,428,231
Ensembl chrNW_004624832:4,404,245...4,428,231 		JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein NOT|involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624788:11,772,268...11,849,040
Ensembl chrNW_004624788:11,772,396...11,845,765 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:21224392) UniProt PMID:21224392 NCBI chrNW_004624751:27,543,768...27,760,536
Ensembl chrNW_004624751:27,543,702...27,759,271 		JBrowse link
G Pinx1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:19393617) UniProt PMID:19393617 NCBI chrNW_004624758:24,589,990...24,666,355
Ensembl chrNW_004624758:24,589,743...24,666,598 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:5,016,284...5,020,264
Ensembl chrNW_004624772:5,016,204...5,019,612 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family involved_in ISO (PMID:24561039) UniProt PMID:24561039 NCBI chrNW_004624781:6,699,926...6,718,020
Ensembl chrNW_004624781:6,699,926...6,718,545 		JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog involved_in ISO (PMID:19465021) UniProt PMID:19465021 NCBI chrNW_004624744:24,914,717...24,916,940
Ensembl chrNW_004624744:24,915,703...24,916,800 		JBrowse link
G Seh1l SEH1 like nucleoporin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624770:19,913,601...19,938,387 JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624778:13,948,567...13,968,643
Ensembl chrNW_004624778:13,953,390...13,968,683 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISO (PMID:28495837) UniProt PMID:28495837 NCBI chrNW_004624776:16,412,683...16,450,784
Ensembl chrNW_004624776:16,413,048...16,445,892 		JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624733:20,326,565...20,350,937
Ensembl chrNW_004624733:20,326,893...20,350,923 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624746:17,044,173...17,059,295
Ensembl chrNW_004624746:17,047,519...17,054,738 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chrNW_004624792:9,098,291...9,128,931 JBrowse link
G Zw10 zw10 kinetochore protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:9,221,123...9,255,294
Ensembl chrNW_004624784:9,221,128...9,255,284 		JBrowse link
attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) UniProt PMID:22581055 NCBI chrNW_004624746:808,463...813,464
Ensembl chrNW_004624746:809,252...812,993 		JBrowse link
G Cenpc centromere protein C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:1,422,857...1,498,726 JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:15843429) UniProt PMID:15843429 NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076 		JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624793:109,854...121,461
Ensembl chrNW_004624793:111,025...113,526 		JBrowse link
G Kif2c kinesin family member 2C involved_in ISO (PMID:23891108) UniProt PMID:23891108 NCBI chrNW_004624906:633,635...660,149
Ensembl chrNW_004624906:633,754...660,254 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492 		JBrowse link
G Mapre1 microtubule associated protein RP/EB family member 1 involved_in ISO (PMID:23001180)
(PMID:36592928) 		UniProt PMID:23001180 PMID:36592928 NCBI chrNW_004624842:6,416,877...6,444,043 JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:9,285,475...9,289,659
Ensembl chrNW_004624786:9,285,830...9,289,454 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624770:12,937,887...12,974,352
Ensembl chrNW_004624770:12,939,763...12,974,162 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624826:1,794,084...1,831,009
Ensembl chrNW_004624826:1,798,737...1,831,112 		JBrowse link
G Seh1l SEH1 like nucleoporin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624770:19,913,601...19,938,387 JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624778:13,948,567...13,968,643
Ensembl chrNW_004624778:13,953,390...13,968,683 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISO (PMID:29487209)
(PMID:28479321) 		UniProt PMID:28479321 PMID:29487209 NCBI chrNW_004624776:16,412,683...16,450,784
Ensembl chrNW_004624776:16,413,048...16,445,892 		JBrowse link
lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO (PMID:23891108) UniProt PMID:23891108 NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076 		JBrowse link
microtubule plus-end directed mitotic chromosome migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO (PMID:25908662) UniProt PMID:25908662 NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076 		JBrowse link
mitotic sister chromatid biorientation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO (PMID:22371557) UniProt PMID:22371557 NCBI chrNW_004624786:10,769,797...10,775,142
Ensembl chrNW_004624786:10,765,610...10,775,112 		JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248), (PMID:24157919) UniProt PMID:17938248 PMID:24157919 NCBI chrNW_004624733:16,459,383...16,469,343 JBrowse link
negative regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 involved_in ISO (PMID:30409912) UniProt PMID:30409912 NCBI chrNW_004624754:2,304,476...2,332,705
Ensembl chrNW_004624754:2,304,634...2,330,946 		JBrowse link
positive regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:21242313) UniProt PMID:21242313 NCBI chrNW_004624771:14,756,088...14,766,106
Ensembl chrNW_004624771:14,756,100...14,765,832 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:23001180) UniProt PMID:23001180 NCBI chrNW_004624821:5,387,212...5,489,013 JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO (PMID:30409912) UniProt PMID:30409912 NCBI chrNW_004624767:20,668,759...20,675,367
Ensembl chrNW_004624767:20,666,763...20,675,164 		JBrowse link
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO (PMID:28751710) CACAO PMID:28751710 NCBI chrNW_004624786:10,769,797...10,775,142
Ensembl chrNW_004624786:10,765,610...10,775,112 		JBrowse link
regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin dependent kinase 1 involved_in ISO (PMID:28479321) UniProt PMID:28479321 NCBI chrNW_004624791:2,891,239...2,915,001 JBrowse link
repair of mitotic kinetochore microtubule attachment defect term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO (PMID:22371557) UniProt PMID:22371557 NCBI chrNW_004624786:10,769,797...10,775,142
Ensembl chrNW_004624786:10,765,610...10,775,112 		JBrowse link
G Ttk TTK protein kinase involved_in ISO (PMID:18243099), (PMID:28441529) UniProt PMID:18243099 PMID:28441529 NCBI chrNW_004624819:6,631,697...6,682,181 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17647
    cellular process 17219
      cell cycle process 1201
        mitotic cell cycle process 686
          mitotic metaphase chromosome alignment 60
            attachment of mitotic spindle microtubules to kinetochore + 21
            microtubule plus-end directed mitotic chromosome migration 1
            mitotic metaphase chromosome recapture 0
            repair of mitotic kinetochore microtubule attachment defect + 2
Path 2
Term Annotations click to browse term
  biological_process 17647
    cellular process 17219
      cellular component organization or biogenesis 7010
        cellular component organization 6807
          organelle organization 3444
            organelle fission 498
              nuclear division 442
                mitotic nuclear division 260
                  mitotic sister chromatid segregation 178
                    mitotic metaphase chromosome alignment 60
                      attachment of mitotic spindle microtubules to kinetochore + 21
                      microtubule plus-end directed mitotic chromosome migration 1
                      mitotic metaphase chromosome recapture 0
                      repair of mitotic kinetochore microtubule attachment defect + 2
paths to the root