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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic sister chromatid cohesion
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Accession:GO:0007064 term browser browse the term
Definition:The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.


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mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 acts_upstream_of_or_within ISO MGI:1353578 (MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:3710433 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdca5 cell division cycle associated 5 involved_in ISO
IBA
UniProtKB:Q29RF7 (PMID:17349791), (PMID:21111234)
UniProtKB:Q96FF9 (MGI:4936811|PMID:21111234)
PMID:21873635
RGD PMID:17349791 PMID:21111234 PMID:21873635 MGI:4936811, RGD:13792537 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578
JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO (PMID:20705812) RGD PMID:20705812 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842
JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:16100726) RGD PMID:16100726 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
IBA
UniProtKB:Q96FF9 (PMID:21111234)
PMID:21873635
RGD PMID:21111234 PMID:21873635 RGD:13792537 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669
JBrowse link
G Pds5b PDS5 cohesin associated factor B involved_in IEA
IBA
ISS
ISO
GO_REF:0000002
PMID:21873635
GO_REF:0000024
(PMID:15855230)
GO_REF:0000107
InterPro
UniProt
RGD
Ensembl
PMID:15855230 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596
JBrowse link
G Pogz pogo transposable element derived with ZNF domain involved_in ISO (PMID:20562864) RGD PMID:20562864 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin acts_upstream_of_or_within ISO MGI:1859866 (MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:3710433 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:140,160,128...140,188,324
Ensembl chr 3:140,160,118...140,188,298
JBrowse link
G Rec8 REC8 meiotic recombination protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326
JBrowse link
G Smc1a structural maintenance of chromosomes 1A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056
JBrowse link
G Smc1b structural maintenance of chromosomes 1B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:116,180,987...116,242,778
Ensembl chr 7:116,180,987...116,242,744
JBrowse link
establishment of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO (PMID:27422821) RGD PMID:27422821 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842
JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO
IBA
(PMID:16682347), (PMID:19907496)
PMID:21873635
RGD PMID:16682347 PMID:19907496 PMID:21873635 RGD:13792537 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor involved_in IBA
ISO
PMID:21873635
(PMID:16682347), (PMID:16802858)
RGD PMID:16682347 PMID:16802858 PMID:21873635 RGD:13792537 NCBI chr16:19,383,847...19,414,996
Ensembl chr16:19,383,492...19,408,727
JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:16682347) RGD PMID:16682347 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA
(PMID:20551165)
GO_REF:0000107
RGD
Ensembl
PMID:20551165 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
mitotic cohesin loading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nipbl NIPBL, cohesin loading factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787
JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO (PMID:17502424) RGD PMID:17502424 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842
JBrowse link
G Sgo1 shugoshin 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805
JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit involved_in ISO (PMID:27422821) RGD PMID:27422821 NCBI chr  X:151,656,056...151,661,304
Ensembl chr  X:151,656,056...151,661,252
JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISO
IEA
(PMID:26373281)
GO_REF:0000107
RGD
Ensembl
PMID:26373281 GO_REF:0000107 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Tnks tankyrase involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260
JBrowse link
positive regulation of maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
ISS
(PMID:19502785)
GO_REF:0000024
RGD
UniProt
PMID:19502785 GO_REF:0000024 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149
JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 1:243,782,781...243,845,409
Ensembl chr 1:243,782,246...243,845,250
JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:19502785) RGD PMID:19502785 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    cellular process 18342
      cell cycle process 1175
        sister chromatid cohesion 56
          mitotic sister chromatid cohesion 28
            establishment of mitotic sister chromatid cohesion + 2
            maintenance of mitotic sister chromatid cohesion + 12
            mitotic sister chromatid cohesion, arms + 0
            mitotic sister chromatid cohesion, centromeric + 4
            mitotic sister chromatid cohesion, telomeric + 2
Path 2
Term Annotations click to browse term
  biological_process 19494
    cellular process 18342
      cellular component organization or biogenesis 6483
        cellular component organization 6237
          organelle organization 3753
            organelle fission 508
              nuclear division 456
                mitotic nuclear division 289
                  mitotic sister chromatid segregation 161
                    mitotic sister chromatid cohesion 28
                      establishment of mitotic sister chromatid cohesion + 2
                      maintenance of mitotic sister chromatid cohesion + 12
                      mitotic sister chromatid cohesion, arms + 0
                      mitotic sister chromatid cohesion, centromeric + 4
                      mitotic sister chromatid cohesion, telomeric + 2
paths to the root