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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic sister chromatid cohesion
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Accession:GO:0007064 term browser browse the term
Definition:The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.

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mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 acts_upstream_of_or_within ISO MGI:1353578 (MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:3710433 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015 		JBrowse link
G Cdca5 cell division cycle associated 5 involved_in ISO
IBA		 UniProtKB:Q29RF7 (PMID:17349791), (PMID:21111234)
UniProtKB:Q96FF9 (MGI:4936811|PMID:21111234)
PMID:21873635		 RGD PMID:17349791 PMID:21111234, PMID:21873635 MGI:4936811, RGD:13792537 NCBI chr 1:221,448,661...221,462,235
Ensembl chr 1:221,448,661...221,462,233 		JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:39,077,580...39,087,880
Ensembl chr19:39,077,580...39,087,880 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO (PMID:20705812) RGD PMID:20705812 NCBI chr10:59,695,403...59,698,398
Ensembl chr10:59,695,913...59,698,168 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:61,508,162...61,530,830
Ensembl chr11:61,462,994...61,530,837
Ensembl chr11:61,462,994...61,530,837 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:16100726) RGD PMID:16100726 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820 		JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
IBA		 UniProtKB:Q96FF9 (PMID:21111234)
PMID:21873635		 RGD PMID:21111234, PMID:21873635 RGD:13792537 NCBI chr14:44,185,445...44,282,308
Ensembl chr14:44,185,446...44,280,079 		JBrowse link
G Pds5b PDS5 cohesin associated factor B involved_in IEA
IBA
ISS
ISO		 GO_REF:0000002
PMID:21873635
GO_REF:0000024
(PMID:15855230)
GO_REF:0000107		 InterPro
UniProt
RGD
Ensembl		 PMID:15855230, PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr12:659,995...794,042
Ensembl chr12:660,011...794,042 		JBrowse link
G Pogz pogo transposable element derived with ZNF domain involved_in ISO (PMID:20562864) RGD PMID:20562864 NCBI chr 2:195,995,322...196,041,500
Ensembl chr 2:195,996,521...196,041,497 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin acts_upstream_of_or_within ISO MGI:1859866 (MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:3710433 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673 		JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:147,163,335...147,191,008
Ensembl chr 3:147,163,838...147,188,929 		JBrowse link
G Rec8 REC8 meiotic recombination protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:34,296,922...34,304,387
Ensembl chr15:34,296,922...34,304,552 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:125,966,480...126,028,287
Ensembl chr 7:125,966,480...126,028,279 		JBrowse link
establishment of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO (PMID:27422821) RGD PMID:27422821 NCBI chr11:61,508,162...61,530,830
Ensembl chr11:61,462,994...61,530,837
Ensembl chr11:61,462,994...61,530,837 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820 		JBrowse link
maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO
IBA		 (PMID:16682347), (PMID:19907496)
PMID:21873635		 RGD PMID:16682347 PMID:19907496, PMID:21873635 RGD:13792537 NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569 		JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor involved_in IBA
ISO		 PMID:21873635
(PMID:16682347), (PMID:16802858)		 RGD PMID:16682347 PMID:16802858, PMID:21873635 RGD:13792537 NCBI chr16:21,132,115...21,163,257
Ensembl chr16:21,132,147...21,163,257 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:16682347) RGD PMID:16682347 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA		 (PMID:20551165)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551165 GO_REF:0000107 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342 		JBrowse link
mitotic cohesin loading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nipbl NIPBL, cohesin loading factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820 		JBrowse link
mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr10:16,259,728...16,266,069
Ensembl chr10:16,259,728...16,266,061 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO (PMID:17502424) RGD PMID:17502424 NCBI chr11:61,508,162...61,530,830
Ensembl chr11:61,462,994...61,530,837
Ensembl chr11:61,462,994...61,530,837 		JBrowse link
G Sgo1 shugoshin 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr 9:4,420,158...4,435,939
Ensembl chr 9:4,421,069...4,436,601 		JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit involved_in ISO (PMID:27422821) RGD PMID:27422821 NCBI chr  X:156,863,655...156,868,950
Ensembl chr  X:156,863,754...156,868,950 		JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISO
IEA		 (PMID:26373281)
GO_REF:0000107		 RGD
Ensembl		 PMID:26373281 GO_REF:0000107 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr16:60,925,093...61,067,192
Ensembl chr16:60,925,093...61,067,192 		JBrowse link
positive regulation of maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
ISS		 (PMID:19502785)
GO_REF:0000024		 RGD
UniProt		 PMID:19502785 GO_REF:0000024 NCBI chr 7:99,677,295...99,900,765
Ensembl chr 7:99,677,290...99,900,764 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:4,095,126...4,195,819
Ensembl chr 2:4,095,129...4,195,810 		JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 1:264,670,836...264,733,465
Ensembl chr 1:264,670,841...264,733,306 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:19502785) RGD PMID:19502785 NCBI chr 1:240,977,898...241,046,273
Ensembl chr 1:240,977,898...241,046,256 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cell cycle process 1174
        sister chromatid cohesion 56
          mitotic sister chromatid cohesion 28
            establishment of mitotic sister chromatid cohesion + 2
            maintenance of mitotic sister chromatid cohesion + 12
            mitotic sister chromatid cohesion, arms + 0
            mitotic sister chromatid cohesion, centromeric + 4
            mitotic sister chromatid cohesion, telomeric + 2
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          organelle organization 4060
            organelle fission 508
              nuclear division 456
                mitotic nuclear division 289
                  mitotic sister chromatid segregation 161
                    mitotic sister chromatid cohesion 28
                      establishment of mitotic sister chromatid cohesion + 2
                      maintenance of mitotic sister chromatid cohesion + 12
                      mitotic sister chromatid cohesion, arms + 0
                      mitotic sister chromatid cohesion, centromeric + 4
                      mitotic sister chromatid cohesion, telomeric + 2
paths to the root