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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic sister chromatid cohesion
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Accession:GO:0007064 term browser browse the term
Definition:The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.


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mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc20 cell division cycle 20 acts_upstream_of_or_within ISO MGI:1353578 (MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:3710433 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdca5 cell division cycle associated 5 involved_in ISO
IBA		 UniProtKB:Q29RF7 (PMID:17349791), (PMID:21111234)
PMID:21873635
UniProtKB:Q96FF9 (MGI:4936811|PMID:21111234)		 RGD PMID:17349791 PMID:21111234 PMID:21873635 MGI:4936811, RGD:13792537 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578 		JBrowse link
G Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:1,630,560...1,686,803
Ensembl chr18:1,631,954...1,686,942 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO (PMID:20705812) RGD PMID:20705812 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:16100726) RGD PMID:16100726 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
IBA		 UniProtKB:Q96FF9 (PMID:21111234)
PMID:21873635		 RGD PMID:21111234 PMID:21873635 RGD:13792537 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669 		JBrowse link
G Pds5b PDS5 cohesin associated factor B involved_in IEA
IBA
ISS
ISO		 GO_REF:0000002
PMID:21873635
GO_REF:0000024
(PMID:15855230)
GO_REF:0000107		 InterPro
UniProt
RGD
Ensembl		 PMID:15855230 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596 		JBrowse link
G Pogz pogo transposable element derived with ZNF domain involved_in ISO (PMID:20562864) RGD PMID:20562864 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin acts_upstream_of_or_within ISO MGI:1859866 (MGI:3710433|PMID:17325031) RGD PMID:17325031 MGI:3710433 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
establishment of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO (PMID:27422821) RGD PMID:27422821 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO
IBA		 (PMID:16682347), (PMID:19907496)
PMID:21873635		 RGD PMID:16682347 PMID:19907496 PMID:21873635 RGD:13792537 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor involved_in IBA
ISO		 PMID:21873635
(PMID:16682347), (PMID:16802858)		 RGD PMID:16682347 PMID:16802858 PMID:21873635 RGD:13792537 NCBI chr16:19,383,847...19,414,996
Ensembl chr16:19,383,492...19,408,727 		JBrowse link
G Nipbl NIPBL, cohesin loading factor involved_in ISO (PMID:16682347) RGD PMID:16682347 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA		 (PMID:20551165)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551165 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
mitotic cohesin loading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nipbl NIPBL, cohesin loading factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit involved_in ISO (PMID:17502424) RGD PMID:17502424 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Sgo1 shugoshin 1 involved_in ISO (PMID:24157919) RGD PMID:24157919 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805 		JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit involved_in ISO (PMID:27422821) RGD PMID:27422821 NCBI chr  X:151,656,056...151,661,304
Ensembl chr  X:151,656,056...151,661,252 		JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
positive regulation of maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in ISO (PMID:26373281) RGD PMID:26373281 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase involved_in ISO
ISS		 (PMID:19502785)
GO_REF:0000024		 RGD
UniProt		 PMID:19502785 GO_REF:0000024 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149 		JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 1:243,782,781...243,845,409
Ensembl chr 1:243,782,246...243,845,250 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 involved_in ISO (PMID:19502785) RGD PMID:19502785 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cell cycle process 1220
        sister chromatid cohesion 56
          mitotic sister chromatid cohesion 27
            establishment of mitotic sister chromatid cohesion + 2
            maintenance of mitotic sister chromatid cohesion + 12
            mitotic sister chromatid cohesion, arms + 0
            mitotic sister chromatid cohesion, centromeric + 4
            mitotic sister chromatid cohesion, telomeric + 2
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          organelle organization 3900
            organelle fission 516
              nuclear division 464
                mitotic nuclear division 295
                  mitotic sister chromatid segregation 168
                    mitotic sister chromatid cohesion 27
                      establishment of mitotic sister chromatid cohesion + 2
                      maintenance of mitotic sister chromatid cohesion + 12
                      mitotic sister chromatid cohesion, arms + 0
                      mitotic sister chromatid cohesion, centromeric + 4
                      mitotic sister chromatid cohesion, telomeric + 2
paths to the root