Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cell cycle arrest
go back to main search page
Accession:GO:0007050 term browser browse the term
Definition:A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
Synonyms:exact_synonym: arrest of cell cycle progression;   cessation of cell cycle;   termination of cell cycle


show annotations for term's descendants       view all columns           Sort by:
 
cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AK1 adenylate kinase 1 JBrowse link 1 268,355,032 268,365,659 RGD:14298760
G APBB2 amyloid beta precursor protein binding family B member 2 JBrowse link 8 31,921,587 32,302,237 RGD:14298760
G APC APC regulator of WNT signaling pathway JBrowse link 2 116,913,354 116,985,303 RGD:14298760
G ATM ATM serine/threonine kinase JBrowse link 9 36,620,656 36,759,555 RGD:14298760
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 5 59,731,224 59,735,831 RGD:14298760
G CDKN1C cyclin dependent kinase inhibitor 1C JBrowse link 2 2,019,391 2,022,092 RGD:14298760
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 1 200,666,250 200,770,880 RGD:14298760
G CDKN2C cyclin dependent kinase inhibitor 2C JBrowse link 6 161,160,290 161,166,681 RGD:14298760
G CDKN2D cyclin dependent kinase inhibitor 2D JBrowse link 2 69,337,428 69,339,998 RGD:14298760
G CDKN3 cyclin dependent kinase inhibitor 3 JBrowse link 1 183,792,606 183,809,178 RGD:14298760
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 8 69,932,646 69,935,861 RGD:14298760
G DDIT3 DNA damage inducible transcript 3 JBrowse link 5 22,785,441 22,789,867 RGD:14298760
G ERN1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 12 14,881,913 14,963,290 RGD:14298760
G ERN2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 3 22,510,067 22,537,872 RGD:14298760
G FOXO4 forkhead box O4 JBrowse link X 57,132,549 57,140,377 RGD:14298760
G GAS2L1 growth arrest specific 2 like 1 JBrowse link 14 46,449,767 46,455,278 RGD:14298760
G HRAS HRas proto-oncogene, GTPase JBrowse link 2 299,662 302,539 RGD:14298760
G ICAM2 intercellular adhesion molecule 2 JBrowse link 12 14,986,636 14,991,639 RGD:14298760
G IFNG interferon gamma JBrowse link 5 32,477,906 32,482,670 RGD:14298760
G IL12A interleukin 12A JBrowse link 13 99,733,394 99,741,078 RGD:14298760
G IL12B interleukin 12B JBrowse link 16 64,143,268 64,158,929 RGD:14298760
G INHBA inhibin subunit beta A JBrowse link 12
18
53,115,379
52,889,684
53,117,128
52,909,260
RGD:14298760
G IRF6 interferon regulatory factor 6 JBrowse link 9 133,164,360 133,184,045 RGD:14298760
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 1 164,381,892 164,469,313 RGD:14298760
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 JBrowse link 15 79,174,444 79,378,520 RGD:14298760
G MSH2 mutS homolog 2 JBrowse link 3 93,082,958 93,163,556 RGD:14298760
G NOTCH1 notch receptor 1 RGD:14298760
G NOTCH2 notch receptor 2 JBrowse link 4 100,951,522 101,152,348 RGD:14298760
G P14ARF p14ARF protein JBrowse link 1 200,774,496 200,799,149 RGD:14298760
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 8 131,002,973 131,058,932 RGD:14298760
G PML promyelocytic leukemia JBrowse link 7 59,405,044 59,450,155 RGD:14298760
G PPM1G protein phosphatase, Mg2+/Mn2+ dependent 1G JBrowse link 3 111,748,012 111,770,868 RGD:14298760
G RASSF1 Ras association domain family member 1 JBrowse link 13 32,816,156 32,825,486 RGD:14298760
G RB1 RB transcriptional corepressor 1 JBrowse link 11 19,186,754 19,317,642 RGD:14298760
G RNF112 ring finger protein 112 JBrowse link 12 60,117,452 60,124,071 RGD:14298760
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog JBrowse link 15 61,140,687 61,143,397 RGD:14298760
G SKIL SKI like proto-oncogene JBrowse link 13 109,029,831 109,059,176 RGD:14298760
G STK11 serine/threonine kinase 11 JBrowse link 2 77,229,888 77,249,322 RGD:14298760
G TBRG1 transforming growth factor beta regulator 1 JBrowse link 9 51,865,312 51,878,259 RGD:14298760
G TCF7L2 transcription factor 7 like 2 JBrowse link 14 123,343,695 123,547,332 RGD:14298760
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:14298760
G TGFB2 transforming growth factor beta 2 JBrowse link 10 8,306,136 8,435,307 RGD:14298760
G THBS1 thrombospondin 1 JBrowse link 1 131,728,781 131,746,098 RGD:14298760
G TP53INP1 tumor protein p53 inducible nuclear protein 1 JBrowse link 4 41,747,654 41,766,688 RGD:14298760
G TP73 tumor protein p73 JBrowse link 6 65,169,770 65,228,997 RGD:14298760
G UHMK1 U2AF homology motif kinase 1 JBrowse link 4 88,029,332 88,052,935 RGD:14298760
G WHAMM WASP homolog associated with actin, golgi membranes and microtubules JBrowse link 7 52,108,867 52,140,333 RGD:14298760
G WNT10B Wnt family member 10B JBrowse link 5 14,997,377 15,013,928 RGD:14298760
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 7 32,354,776 32,363,771 RGD:14298760
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 5 89,257,603 89,480,414 RGD:14298760
G MDM2 MDM2 proto-oncogene JBrowse link 5 33,105,717 33,137,602 RGD:14298760
G PIDD1 p53-induced death domain protein 1 JBrowse link 2 499,294 505,740 RGD:14298760
G PML promyelocytic leukemia JBrowse link 7 59,405,044 59,450,155 RGD:14298760
G RPL26 ribosomal protein L26 JBrowse link 12 53,548,313 53,553,453 RGD:14298760
G SOCS2 suppressor of cytokine signaling 2 JBrowse link 5 89,581,081 89,587,424 RGD:14298760
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:14298760
mitotic cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDC14B cell division cycle 14B JBrowse link 10 25,471,976 25,590,022 RGD:14298760
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 7 32,354,776 32,363,771 RGD:14298760
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 5 59,731,224 59,735,831 RGD:14298760
G DDIAS DNA damage induced apoptosis suppressor JBrowse link 9 17,077,884 17,097,597 RGD:14298760
G FAP fibroblast activation protein alpha JBrowse link 15 68,831,281 68,902,416 RGD:14298760
G GADD45A growth arrest and DNA damage inducible alpha JBrowse link 6 144,940,702 144,944,089 RGD:14298760
G GADD45GIP1 GADD45G interacting protein 1 JBrowse link 2 66,087,421 66,089,578 RGD:14298760
G MCPH1 microcephalin 1 JBrowse link 15 37,455,186 37,674,971 RGD:14298760
G NKX3-1 NK3 homeobox 1 JBrowse link 14 7,783,296 7,787,036 RGD:14298760
G PNPT1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 3 85,595,356 85,639,665 RGD:14298760
G RGCC regulator of cell cycle JBrowse link 11 25,481,845 25,496,548 RGD:14298760
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:14298760
negative regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALR calreticulin JBrowse link 2 66,098,263 66,102,074 RGD:14298760
G CCND1 cyclin D1 JBrowse link 2 3,621,242 3,633,380 RGD:14298760
G CDK4 cyclin dependent kinase 4 JBrowse link 5 23,039,206 23,041,959 RGD:14298760
G FGF10 fibroblast growth factor 10 JBrowse link 16 28,695,465 28,779,953 RGD:14298760
G FOXE3 forkhead box E3 JBrowse link 6 164,130,638 164,133,218 RGD:14298760
G FZD9 frizzled class receptor 9 JBrowse link 3 10,753,294 10,762,812 RGD:14298760
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 3 711,427 715,982 RGD:14298760
G HSP90AB1 heat shock protein 90 alpha family class B member 1 JBrowse link 7 39,237,299 39,250,479 RGD:14298760
G LOC100154415 zinc finger protein 268 JBrowse link 14 22,379,600 22,399,987 RGD:14298760
G MDM2 MDM2 proto-oncogene JBrowse link 5 33,105,717 33,137,602 RGD:14298760
G MDM4 MDM4 regulator of p53 JBrowse link 9 65,175,488 65,219,747 RGD:14298760
G MIF macrophage migration inhibitory factor JBrowse link 14 49,840,303 49,841,063 RGD:14298760
G MLXIPL MLX interacting protein like JBrowse link 3 10,898,675 10,934,257 RGD:14298760
G TFAP4 transcription factor AP-4 JBrowse link 3 38,043,735 38,060,820 RGD:14298760
positive regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRCA1 BRCA1 DNA repair associated JBrowse link 12 19,788,087 19,854,515 RGD:14298760
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 JBrowse link 12 42,456,063 42,494,494 RGD:14298760
G CRLF3 cytokine receptor like factor 3 JBrowse link 12 42,933,417 42,991,395 RGD:14298760
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:14298760
G FAP fibroblast activation protein alpha JBrowse link 15 68,831,281 68,902,416 RGD:14298760
G FOXO4 forkhead box O4 JBrowse link X 57,132,549 57,140,377 RGD:14298760
G GATA6 GATA binding protein 6 JBrowse link 6 107,282,709 107,314,725 RGD:14298760
G ID2 inhibitor of DNA binding 2 JBrowse link 3 127,500,759 127,503,207 RGD:14298760
G MED25 mediator complex subunit 25 JBrowse link 6 54,834,303 54,849,539 RGD:14298760
G MYBBP1A MYB binding protein 1a JBrowse link 12 50,491,042 50,506,085 RGD:14298760
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 8 131,002,973 131,058,932 RGD:14298760
G POU4F1 POU class 4 homeobox 1 JBrowse link 11 50,729,746 50,732,626 RGD:14298760
G PRKACA protein kinase cAMP-activated catalytic subunit alpha JBrowse link 2 65,074,876 65,095,564 RGD:14298760
G RGCC regulator of cell cycle JBrowse link 11 25,481,845 25,496,548 RGD:14298760
G RNF112 ring finger protein 112 JBrowse link 12 60,117,452 60,124,071 RGD:14298760
G RRP8 ribosomal RNA processing 8 JBrowse link 9 3,152,162 3,169,380 RGD:14298760
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:14298760
G TP73 tumor protein p73 JBrowse link 6 65,169,770 65,228,997 RGD:14298760
G UHRF2 ubiquitin like with PHD and ring finger domains 2 JBrowse link 1 215,730,212 215,807,630 RGD:14298760
regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BIN1 bridging integrator 1 JBrowse link 15 25,328,679 25,379,675 RGD:14298760
G FOXM1 forkhead box M1 JBrowse link 5 67,246,219 67,263,215 RGD:14298760
G MASTL microtubule associated serine/threonine kinase like JBrowse link 10 48,855,895 48,877,504 RGD:14298760
G NEUROD1 neuronal differentiation 1 JBrowse link 15 87,175,629 87,179,953 RGD:14298760
G SDE2 SDE2 telomere maintenance homolog JBrowse link 10 13,879,482 13,897,847 RGD:14298760
G SLC25A33 solute carrier family 25 member 33 JBrowse link 6 69,934,810 69,969,091 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    cellular process 14114
      cell cycle process 870
        cell cycle arrest 95
          G1 cell cycle arrest in response to nitrogen starvation + 0
          cell cycle arrest of committed forebrain neuronal progenitor cell 0
          mitotic cell cycle arrest + 12
          negative regulation of cell cycle arrest 14
          positive regulation of cell cycle arrest + 27
          regulation of cell cycle arrest + 46
Path 2
Term Annotations click to browse term
  biological_process 14973
    biological regulation 10106
      regulation of biological process 9516
        negative regulation of biological process 3735
          negative regulation of cellular process 3400
            negative regulation of cell cycle 330
              cell cycle arrest 95
                G1 cell cycle arrest in response to nitrogen starvation + 0
                cell cycle arrest of committed forebrain neuronal progenitor cell 0
                mitotic cell cycle arrest + 12
                negative regulation of cell cycle arrest 14
                positive regulation of cell cycle arrest + 27
                regulation of cell cycle arrest + 46
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.