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ONTOLOGY REPORT - ANNOTATIONS


Term:cell cycle arrest
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Accession:GO:0007050 term browser browse the term
Definition:A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
Synonyms:exact_synonym: arrest of cell cycle progression;   cessation of cell cycle;   termination of cell cycle


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cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ak1 adenylate kinase 1 JBrowse link 2 32,621,758 32,635,058 RGD:2290270
G Apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 JBrowse link 7 105,558,465 105,581,924 RGD:2290270
G Apbb2 amyloid beta (A4) precursor protein-binding, family B, member 2 JBrowse link 5 66,298,725 66,619,064 RGD:2290270
G Apc APC, WNT signaling pathway regulator JBrowse link 18 34,220,297 34,322,190 RGD:2290270
G Atm ataxia telangiectasia mutated JBrowse link 9 53,437,122 53,536,828 RGD:2290270
G AY074887 cDNA sequence AY074887 JBrowse link 9 54,950,244 54,950,954 RGD:2290270
G Brinp1 bone morphogenic protein/retinoic acid inducible neural specific 1 JBrowse link 4 68,761,372 68,954,397 RGD:2290270
G Brinp2 bone morphogenic protein/retinoic acid inducible neural-specific 2 JBrowse link 1 158,245,265 158,356,528 RGD:2290270
G Brinp3 bone morphogenetic protein/retinoic acid inducible neural specific 3 JBrowse link 1 146,495,629 146,902,472 RGD:2290270
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:2290270
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:2290270
G Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) JBrowse link 7 143,458,339 143,461,059 RGD:2290270
G Cdkn2a cyclin dependent kinase inhibitor 2A JBrowse link 4 89,274,473 89,294,619 RGD:2290270
G Cdkn2b cyclin dependent kinase inhibitor 2B JBrowse link 4 89,306,289 89,311,032 RGD:2290270
G Cdkn2c cyclin dependent kinase inhibitor 2C JBrowse link 4 109,660,876 109,666,756 RGD:2290270
G Cdkn2d cyclin dependent kinase inhibitor 2D JBrowse link 9 21,288,459 21,291,421 RGD:2290270
G Cdkn3 cyclin-dependent kinase inhibitor 3 JBrowse link 14 46,760,461 46,771,530 RGD:2290270
G Cgref1 cell growth regulator with EF hand domain 1 JBrowse link 5 30,933,143 30,945,480 RGD:2290270
G Cgrrf1 cell growth regulator with ring finger domain 1 JBrowse link 14 46,832,134 46,854,198 RGD:2290270
G Ddias DNA damage-induced apoptosis suppressor JBrowse link 7 92,857,525 92,874,917 RGD:2290270
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:2290270
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 2 118,388,583 118,475,234 RGD:2290270
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 JBrowse link 11 106,397,620 106,487,796 RGD:2290270
G Ern2 endoplasmic reticulum (ER) to nucleus signalling 2 JBrowse link 7 122,169,893 122,186,239 RGD:2290270
G Foxo4 forkhead box O4 JBrowse link X 101,254,261 101,260,873 RGD:2290270
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha JBrowse link 6 67,035,096 67,037,407 RGD:2290270
G Gas1 growth arrest specific 1 JBrowse link 13 60,174,405 60,177,535 RGD:2290270
G Gas2 growth arrest specific 2 JBrowse link 7 51,861,791 51,995,005 RGD:2290270
G Gas2l1 growth arrest-specific 2 like 1 JBrowse link 11 5,054,131 5,065,348 RGD:2290270
G Hepacam hepatocyte cell adhesion molecule JBrowse link 9 37,367,356 37,386,572 RGD:2290270
G Hras Harvey rat sarcoma virus oncogene JBrowse link 7 141,189,934 141,194,019 RGD:2290270
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:2290270
G Il12a interleukin 12a JBrowse link 3 68,690,644 68,698,550 RGD:2290270
G Il12b interleukin 12b JBrowse link 11 44,400,063 44,414,677 RGD:2290270
G Ilk integrin linked kinase JBrowse link 7 105,736,590 105,742,925 RGD:2290270
G Ing4 inhibitor of growth family, member 4 JBrowse link 6 125,039,848 125,049,265 RGD:2290270
G Inhba inhibin beta-A JBrowse link 13 16,004,256 16,031,609 RGD:2290270
G Irf1 interferon regulatory factor 1 JBrowse link 11 53,769,854 53,778,374 RGD:2290270
G Irf6 interferon regulatory factor 6 JBrowse link 1 193,153,112 193,172,036 RGD:2290270
G Jmy junction-mediating and regulatory protein JBrowse link 13 93,430,097 93,499,808 RGD:2290270
G Kmt2e lysine (K)-specific methyltransferase 2E JBrowse link 5 23,433,036 23,504,235 RGD:2290270
G Map2k1 mitogen-activated protein kinase kinase 1 JBrowse link 9 64,185,769 64,253,605 RGD:2290270
G Map3k20 mitogen-activated protein kinase kinase kinase 20 JBrowse link 2 72,285,637 72,442,610 RGD:2290270
G Men1 multiple endocrine neoplasia 1 JBrowse link 19 6,334,979 6,340,894 RGD:2290270
G Mlf1 myeloid leukemia factor 1 JBrowse link 3 67,374,097 67,400,000 RGD:2290270
G Msh2 mutS homolog 2 JBrowse link 17 87,672,532 87,723,713 RGD:2290270
G Mtbp Mdm2, transformed 3T3 cell double minute p53 binding protein JBrowse link 15 55,557,404 55,626,423 RGD:2290270
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:2290270
G Notch1 notch 1 JBrowse link 2 26,457,902 26,503,822 RGD:2290270
G Notch2 notch 2 JBrowse link 3 98,013,538 98,150,367 RGD:2290270
G Nupr1l nuclear protein transcriptional regulator 1 like JBrowse link 5 129,908,540 129,913,788 RGD:2290270
G Pkd1 polycystin 1, transient receptor poteintial channel interacting JBrowse link 17 24,548,689 24,596,514 RGD:2290270
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 5 104,453,982 104,505,819 RGD:2290270
G Pml promyelocytic leukemia JBrowse link 9 58,217,179 58,249,796 RGD:2290270
G Pmp22 peripheral myelin protein 22 JBrowse link 11 63,128,982 63,159,547 RGD:2290270
G Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform JBrowse link 5 31,202,668 31,220,545 RGD:2290270
G Prr11 proline rich 11 JBrowse link 11 87,089,156 87,108,714 RGD:2290270
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 JBrowse link 9 107,551,434 107,562,267 RGD:2290270
G Rb1 RB transcriptional corepressor 1 JBrowse link 14 73,192,858 73,325,951 RGD:2290270
G Rnf112 ring finger protein 112 JBrowse link 11 61,448,417 61,454,188 RGD:2290270
G Rprm reprimo, TP53 dependent G2 arrest mediator candidate JBrowse link 2 54,084,093 54,085,552 RGD:2290270
G Sgsm3 small G protein signaling modulator 3 JBrowse link 15 80,977,762 81,012,290 RGD:2290270
G Skil SKI-like JBrowse link 3 31,095,058 31,122,923 RGD:2290270
G Slfn1 schlafen 1 JBrowse link 11 83,116,820 83,122,670 RGD:2290270
G Smad3 SMAD family member 3 JBrowse link 9 63,646,766 63,757,994 RGD:2290270
G Sox2 SRY (sex determining region Y)-box 2 JBrowse link 3 34,649,995 34,652,461 RGD:2290270
G Stk11 serine/threonine kinase 11 JBrowse link 10 80,115,767 80,130,679 RGD:2290270
G Tbrg1 transforming growth factor beta regulated gene 1 JBrowse link 9 37,649,182 37,657,312 RGD:2290270
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box JBrowse link 19 55,741,797 55,933,659 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Tgfb2 transforming growth factor, beta 2 JBrowse link 1 186,622,787 186,709,697 RGD:2290270
G Thbs1 thrombospondin 1 JBrowse link 2 118,111,876 118,127,133 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 JBrowse link 4 11,156,441 11,174,379 RGD:2290270
G Trp73 transformation related protein 73 JBrowse link 4 154,056,249 154,139,875 RGD:2290270
G Tsg101 tumor susceptibility gene 101 JBrowse link 7 46,888,949 46,926,320 RGD:2290270
G Uhmk1 U2AF homology motif (UHM) kinase 1 JBrowse link 1 170,193,422 170,215,897 RGD:2290270
G Vash1 vasohibin 1 JBrowse link 12 86,678,700 86,695,688 RGD:2290270
G Wdr6 WD repeat domain 6 JBrowse link 9 108,572,311 108,578,713 RGD:2290270
G Whamm WAS protein homolog associated with actin, golgi membranes and microtubules JBrowse link 7 81,570,655 81,596,837 RGD:2290270
G Wnt10b wingless-type MMTV integration site family, member 10B JBrowse link 15 98,770,712 98,778,206 RGD:2290270
G Zbtb49 zinc finger and BTB domain containing 49 JBrowse link 5 38,189,732 38,220,499 RGD:2290270
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 6 42,264,902 42,282,508 RGD:2290270
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:2290270
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 10 95,174,739 95,324,138 RGD:2290270
G Mdm2 transformed mouse 3T3 cell double minute 2 JBrowse link 10 117,688,875 117,710,758 RGD:2290270
G Pidd1 p53 induced death domain protein 1 JBrowse link 7 141,438,113 141,447,565 RGD:2290270
G Pml promyelocytic leukemia JBrowse link 9 58,217,179 58,249,796 RGD:2290270
G Rbm38 RNA binding motif protein 38 JBrowse link 2 173,021,891 173,034,734 RGD:2290270
G Rpl26 ribosomal protein L26 JBrowse link 11 68,901,566 68,904,534 RGD:2290270
G Sox4 SRY (sex determining region Y)-box 4 JBrowse link 13 28,948,919 28,953,699 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270
mitotic cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc14a CDC14 cell division cycle 14A JBrowse link 3 116,272,553 116,428,742 RGD:2290270
G Cdc14b CDC14 cell division cycle 14B JBrowse link 13 64,192,545 64,274,988 RGD:2290270
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:2290270
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:2290270
G Ddias DNA damage-induced apoptosis suppressor JBrowse link 7 92,857,525 92,874,917 RGD:2290270
G Fap fibroblast activation protein JBrowse link 2 62,500,936 62,575,509 RGD:2290270
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha JBrowse link 6 67,035,096 67,037,407 RGD:2290270
G Gadd45gip1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 JBrowse link 8 84,832,282 84,835,482 RGD:2290270
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 5 19,219,387 20,704,792 RGD:2290270
G Mcph1 microcephaly, primary autosomal recessive 1 JBrowse link 8 18,595,116 18,808,089 RGD:2290270
G Nkx3-1 NK3 homeobox 1 JBrowse link 14 69,190,692 69,194,658 RGD:2290270
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 11 29,130,129 29,161,827 RGD:2290270
G Rgcc regulator of cell cycle JBrowse link 14 79,288,750 79,301,635 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270
negative regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calr calreticulin JBrowse link 8 84,842,088 84,846,931 RGD:2290270
G Cast calpastatin JBrowse link 13 74,692,366 74,808,874 RGD:2290270
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:2290270
G Cdk4 cyclin-dependent kinase 4 JBrowse link 10 127,063,535 127,067,288 RGD:2290270
G Cdk9 cyclin-dependent kinase 9 (CDC2-related kinase) JBrowse link 2 32,705,782 32,712,784 RGD:2290270
G Chek2 checkpoint kinase 2 JBrowse link 5 110,839,800 110,874,140 RGD:2290270
G Evi2b ecotropic viral integration site 2b JBrowse link 11 79,513,385 79,523,762 RGD:2290270
G Fgf10 fibroblast growth factor 10 JBrowse link 13 118,714,699 118,792,573 RGD:2290270
G Foxe3 forkhead box E3 JBrowse link 4 114,924,443 114,926,067 RGD:2290270
G Fzd9 frizzled class receptor 9 JBrowse link 5 135,248,938 135,251,047 RGD:2290270
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 5 139,423,150 139,427,800 RGD:2290270
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 JBrowse link 17 45,567,778 45,573,261 RGD:2290270
G Mdm2 transformed mouse 3T3 cell double minute 2 JBrowse link 10 117,688,875 117,710,758 RGD:2290270
G Mdm4 transformed mouse 3T3 cell double minute 4 JBrowse link 1 132,986,105 133,030,587 RGD:2290270
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) JBrowse link 10 75,859,353 75,860,277 RGD:2290270
G Mlxipl MLX interacting protein-like JBrowse link 5 135,089,890 135,139,768 RGD:2290270
G Nupr1l nuclear protein transcriptional regulator 1 like JBrowse link 5 129,908,540 129,913,788 RGD:2290270
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 JBrowse link 9 107,551,434 107,562,267 RGD:2290270
G Rpl23 ribosomal protein L23 JBrowse link 11 97,777,526 97,782,439 RGD:2290270
G Tfap4 transcription factor AP4 JBrowse link 16 4,544,661 4,560,762 RGD:2290270
positive regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca1 breast cancer 1, early onset JBrowse link 11 101,488,761 101,551,955 RGD:2290270
G Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) JBrowse link 11 80,477,023 80,481,184 RGD:2290270
G Cdkn2a cyclin dependent kinase inhibitor 2A JBrowse link 4 89,274,473 89,294,619 RGD:2290270
G Crlf3 cytokine receptor-like factor 3 JBrowse link 11 80,046,493 80,081,153 RGD:2290270
G Dab2ip disabled 2 interacting protein JBrowse link 2 35,558,446 35,730,994 RGD:2290270
G Fap fibroblast activation protein JBrowse link 2 62,500,936 62,575,509 RGD:2290270
G Foxo4 forkhead box O4 JBrowse link X 101,254,261 101,260,873 RGD:2290270
G Gata6 GATA binding protein 6 JBrowse link 18 11,052,510 11,085,636 RGD:2290270
G Id2 inhibitor of DNA binding 2 JBrowse link 12 25,093,799 25,096,092 RGD:2290270
G Insm1 insulinoma-associated 1 JBrowse link 2 146,221,997 146,225,020 RGD:2290270
G Med25 mediator complex subunit 25 JBrowse link 7 44,876,765 44,892,705 RGD:2290270
G Mybbp1a MYB binding protein (P160) 1a JBrowse link 11 72,441,327 72,451,770 RGD:2290270
G Myog myogenin JBrowse link 1 134,290,004 134,292,548 RGD:2290270
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 5 104,453,982 104,505,819 RGD:2290270
G Pou4f1 POU domain, class 4, transcription factor 1 JBrowse link 14 104,461,675 104,468,118 RGD:2290270
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta JBrowse link 19 6,227,765 6,236,264 RGD:2290270
G Prkaca protein kinase, cAMP dependent, catalytic, alpha JBrowse link 8 83,972,978 83,996,444 RGD:2290270
G Rgcc regulator of cell cycle JBrowse link 14 79,288,750 79,301,635 RGD:2290270
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 13 24,501,524 24,733,806 RGD:2290270
G Rnf112 ring finger protein 112 JBrowse link 11 61,448,417 61,454,188 RGD:2290270
G Rpl23 ribosomal protein L23 JBrowse link 11 97,777,526 97,782,439 RGD:2290270
G Rrp8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) JBrowse link 7 105,731,730 105,737,385 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270
G Trp73 transformation related protein 73 JBrowse link 4 154,056,249 154,139,875 RGD:2290270
G Uhrf2 ubiquitin-like, containing PHD and RING finger domains 2 JBrowse link 19 30,030,430 30,093,726 RGD:2290270
G Zbtb17 zinc finger and BTB domain containing 17 JBrowse link 4 141,444,660 141,467,937 RGD:2290270
regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 32,376,618 32,435,740 RGD:2290270
G Foxm1 forkhead box M1 JBrowse link 6 128,362,994 128,375,886 RGD:2290270
G Neurod1 neurogenic differentiation 1 JBrowse link 2 79,452,637 79,456,636 RGD:2290270
G Sde2 SDE2 telomere maintenance homolog (S. pombe) JBrowse link 1 180,851,151 180,868,113 RGD:2290270
G Slc25a33 solute carrier family 25, member 33 JBrowse link 4 149,744,036 149,774,267 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23110
    cellular process 16749
      cell cycle process 1136
        cell cycle arrest 137
          G1 cell cycle arrest in response to nitrogen starvation + 0
          cell cycle arrest of committed forebrain neuronal progenitor cell 0
          mitotic cell cycle arrest + 14
          negative regulation of cell cycle arrest 20
          positive regulation of cell cycle arrest + 36
          regulation of cell cycle arrest + 59
Path 2
Term Annotations click to browse term
  biological_process 23110
    biological regulation 12505
      regulation of biological process 11872
        negative regulation of biological process 5445
          negative regulation of cellular process 4888
            negative regulation of cell cycle 448
              cell cycle arrest 137
                G1 cell cycle arrest in response to nitrogen starvation + 0
                cell cycle arrest of committed forebrain neuronal progenitor cell 0
                mitotic cell cycle arrest + 14
                negative regulation of cell cycle arrest 20
                positive regulation of cell cycle arrest + 36
                regulation of cell cycle arrest + 59
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.