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ONTOLOGY REPORT - ANNOTATIONS

Term:lysosomal lumen acidification
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Accession:GO:0007042 term browser browse the term
Definition:Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
Synonyms:exact_synonym: lysosome pH reduction


show annotations for term's descendants           Sort by:
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32276428)		 UniProt
RGD		 PMID:32276428 GO_REF:0000024 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IBA
ISO		 PMID:21873635
(PMID:11722572)		 RGD PMID:11722572 PMID:21873635 RGD:13792537 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438 		JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (MGI:6854654|PMID:33966596) RGD PMID:33966596 MGI:6854654 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308 		JBrowse link
G Grn granulin precursor involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:28073925)		 Ensembl
UniProt
RGD		 PMID:28073925 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISS
ISO		 PMID:8895569
(PMID:11722572)		 RGD PMID:11722572 PMID:8895569 RGD:8553248 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:4879078 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231 		JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619 		JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28296633)		 UniProt
RGD		 PMID:28296633 GO_REF:0000024 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108 		JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:47,458,486...47,475,832
Ensembl chr13:47,458,498...47,475,832 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    biological regulation 13447
      regulation of biological quality 3327
        regulation of intracellular pH 80
          regulation of lysosomal lumen pH 21
            lysosomal lumen acidification 12
Path 2
Term Annotations click to browse term
  biological_process 19746
    homeostatic process 1916
      chemical homeostasis 1173
        monoatomic ion homeostasis 656
          monoatomic cation homeostasis 643
            regulation of pH 102
              regulation of cellular pH 89
                regulation of intracellular pH 80
                  intracellular pH reduction 45
                    vacuolar acidification 23
                      lysosomal lumen acidification 12
paths to the root