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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis



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lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492
JBrowse link
G ACP2 acid phosphatase 2, lysosomal involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:894905|PMID:9228031)
(MGI:3522374|PMID:15604265)
GO_Central
GO_Central
MGI
PMID:9228031 PMID:15604265 PMID:21873635 MGI:3522374 MGI:894905 NCBI chr 2:15,334,015...15,342,531
Ensembl chr 2:15,334,001...15,347,770
JBrowse link
G ACP3 acid phosphatase 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr13:73,471,837...73,530,778
Ensembl chr13:73,471,889...73,530,011
JBrowse link
G ACP4 acid phosphatase 4 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 6:55,535,406...55,541,929
Ensembl chr 6:55,536,904...55,541,968
JBrowse link
G AKTIP AKT interacting protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:31,706,253...31,757,878
Ensembl chr 6:31,747,606...31,758,279
JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1330543|PMID:9931340), (MGI:6415001|PMID:30786955) Ensembl
Ensembl
MGI
PMID:9931340 PMID:30786955 GO_REF:0000107 MGI:1330543 MGI:6415001 NCBI chr 2:86,875,922...87,142,722
Ensembl chr 2:86,873,290...87,142,768
JBrowse link
G BECN1 beclin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3801567|PMID:18497889) Ensembl
Ensembl
MGI
PMID:18497889 GO_REF:0000107 MGI:3801567 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G CHMP5 charged multivesicular body protein 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3622513|PMID:16567502) Ensembl
Ensembl
MGI
PMID:16567502 GO_REF:0000107 MGI:3622513 NCBI chr10:33,212,769...33,227,237
Ensembl chr10:33,211,516...33,227,302
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3527911|PMID:15588329)
(MGI:1337525|PMID:10191119), (MGI:1346962|PMID:10527801)
(MGI:1343910|PMID:10440905)
GO_Central
GO_Central
Ensembl
MGI
PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 PMID:21873635 GO_REF:0000107 MGI:1337525 MGI:1343910 MGI:1346962 MGI:3527911 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3512689|PMID:15459177)
GO_Central
GO_Central
Ensembl
MGI
PMID:15459177 PMID:21873635 GO_REF:0000107 MGI:3512689 NCBI chr11:49,105,822...49,128,425
Ensembl chr11:49,105,878...49,129,886
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1203267|PMID:9600738), (MGI:5751614|PMID:26681805)
GO_Central
GO_Central
Ensembl
MGI
PMID:9600738 PMID:21873635 PMID:26681805 GO_REF:0000107 MGI:1203267 MGI:5751614 NCBI chr 1:166,107,895...166,126,054
Ensembl chr 1:166,107,228...166,126,808
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1333651|PMID:10087069), (MGI:65559|PMID:8144516), (MGI:66707|PMID:8160780), (MGI:71226|PMID:7613514) Ensembl
Ensembl
MGI
PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 MGI:1333651 MGI:65559 MGI:66707 MGI:71226 NCBI chr15:33,282,524...33,325,598
Ensembl chr15:33,288,301...33,304,631
JBrowse link
G CLVS1 clavesin 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
InterPro
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 4:72,104,521...72,257,259
Ensembl chr 4:72,105,972...72,257,226
JBrowse link
G CLVS2 clavesin 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 1:39,680,741...39,755,398
Ensembl chr 1:39,682,689...39,752,486
JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:3,441,613...3,464,237
Ensembl chr 9:3,446,075...3,464,226
JBrowse link
G GAA alpha glucosidase involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1275872|PMID:9668092), (MGI:3618942|PMID:15169761)
(MGI:1195358|PMID:9384603), (MGI:1346721|PMID:10547605), (MGI:2136118|PMID:11328962), (MGI:3664400|PMID:12115977)
GO_Central
Ensembl
GO_Central
MGI
PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 More... GO_REF:0000107 MGI:1195358 MGI:1275872 MGI:1346721 MGI:2136118 MGI:3618942 MGI:3664400 NCBI chr12:2,315,807...2,339,867
Ensembl chr12:2,314,591...2,336,988
JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in ISS
IEA
UniProt
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745
JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:82,264,640...82,460,819
Ensembl chr 5:82,361,872...82,460,814
JBrowse link
G GRN granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446
JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:69059|PMID:7937929), (MGI:86923|PMID:9103204)
(MGI:77946|PMID:8747922)
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
(MGI:1097747|PMID:9302266), (MGI:1271008|PMID:9645704), (MGI:1352198|PMID:10591619), (MGI:3033296|PMID:14972652)
Ensembl
Ensembl
MGI
PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 MGI:1097747 MGI:1271008 MGI:1352198 MGI:3033296 MGI:69059 MGI:77946 MGI:83770 MGI:86923 MGI:894634 NCBI chr 7:60,878,531...60,911,537
Ensembl chr 7:60,878,284...60,913,339
JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
(MGI:1271008|PMID:9645704), (MGI:78473|PMID:8789434)
Ensembl
Ensembl
MGI
PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 MGI:1271008 MGI:78473 MGI:83770 MGI:894634 NCBI chr 2:83,745,263...83,784,762
Ensembl chr 2:83,744,627...83,784,759
JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chr 6:152,636,118...152,709,422 JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:66,227,562...66,239,671
Ensembl chr 2:66,227,601...66,244,828
JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:11,817,963...11,919,152
Ensembl chr17:11,818,031...11,923,196
JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (MGI:6415001|PMID:30786955) MGI PMID:30786955 MGI:6415001 NCBI chr14:109,730,597...109,755,288
Ensembl chr14:109,730,598...109,751,985
JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:44,041,684...44,073,661
Ensembl chr14:44,049,707...44,073,621
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (MGI:86916|PMID:9097952)
(MGI:4414887|PMID:19751987)
MGI PMID:9097952 PMID:19751987 MGI:4414887 MGI:86916 NCBI chr 8:334,604...351,970
Ensembl chr 8:334,617...351,969
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA InterPro
InterPro
Ensembl
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 9:6,674,045...6,680,067
Ensembl chr 9:6,672,475...6,680,053
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828
JBrowse link
G LYST lysosomal trafficking regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1099544|PMID:9368050)
(MGI:53816|PMID:4697831), (MGI:53992|PMID:1113502), (MGI:55104|PMID:6170520), (MGI:56449|PMID:4031470)
InterPro
InterPro
MGI
PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 GO_REF:0000002 MGI:1099544 MGI:53816 MGI:53992 MGI:55104 MGI:56449 NCBI chr14:55,433,163...55,634,011
Ensembl chr14:55,433,597...55,633,484
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:4,503,530...4,558,601
Ensembl chr 6:4,503,565...4,558,609
JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5575728|PMID:24423645)
(MGI:5751614|PMID:26681805)
Ensembl
Ensembl
MGI
PMID:24423645 PMID:26681805 GO_REF:0000107 MGI:5575728 MGI:5751614 NCBI chr 8:96,925,063...96,972,390
Ensembl chr 8:96,925,081...96,972,383
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G MYO7A myosin VIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:11,251,187...11,337,618
Ensembl chr 9:11,249,075...11,666,296
JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 Ensembl chr12:20,271,351...20,279,777 JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25365221) MGI
Ensembl
PMID:25365221 GO_REF:0000107 NCBI chr 4:97,918,234...97,949,929
Ensembl chr 4:97,918,245...97,949,931
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3654230|PMID:16542649)
(MGI:3612221|PMID:16368712)
MGI
Ensembl
PMID:16368712 PMID:16542649 GO_REF:0000107 MGI:3612221 MGI:3654230 NCBI chr 6:95,840,906...95,860,858
Ensembl chr 6:95,840,908...95,860,858
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:4879078|PMID:20920792)
GO_Central
Ensembl
GO_Central
MGI
PMID:20920792 PMID:21873635 GO_REF:0000107 MGI:4879078 NCBI chr 4:95,987,524...95,989,527
Ensembl chr 4:95,984,358...95,989,474
JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5749311|PMID:26284655)
(PMID:25365221)
(MGI:6141536|PMID:28237315), (MGI:6433162|PMID:31637311)
MGI
Ensembl
PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 GO_REF:0000107 MGI:5749311 MGI:6141536 MGI:6433162 NCBI chr 1:126,890,464...126,998,014
Ensembl chr 1:126,902,186...127,003,397
Ensembl chr 1:126,902,186...127,003,397
JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6433162|PMID:31637311) Ensembl
MGI
Ensembl
PMID:31637311 GO_REF:0000107 MGI:6433162 NCBI chr 7:36,870,240...36,920,887
Ensembl chr 7:36,870,242...36,920,865
JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5588048|PMID:25066864)
GO_Central
GO_Central
MGI
PMID:21873635 PMID:25066864 MGI:5588048 NCBI chr 9:81,837,654...81,864,215
Ensembl chr 9:81,837,667...81,864,210
JBrowse link
G TPCN2 two pore segment channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,069,267...4,105,065
Ensembl chr 2:4,069,280...4,105,042
JBrowse link
G TPP1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3522013|PMID:15483130) Ensembl
Ensembl
MGI
PMID:15483130 GO_REF:0000107 MGI:3522013 NCBI chr 9:3,135,580...3,143,408
Ensembl chr 9:3,135,642...3,143,404
JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:130,409,121...130,420,467
Ensembl chr 1:130,409,123...130,420,450
JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr 6:37,944,099...37,977,091
Ensembl chr 6:37,944,127...37,986,171
JBrowse link
G WASHC5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6199426|PMID:30061306) Ensembl
Ensembl
MGI
PMID:30061306 GO_REF:0000107 MGI:6199426 NCBI chr 4:14,598,133...14,667,535
Ensembl chr 4:14,598,150...14,668,313
JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25365221) MGI
Ensembl
PMID:25365221 GO_REF:0000107 NCBI chr 7:91,518,444...91,590,480
Ensembl chr 7:91,518,452...91,590,449
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr  X:36,271,154...36,300,240
Ensembl chr  X:36,271,222...36,304,181
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:31,974,715...31,979,062
Ensembl chr15:31,974,724...31,979,059
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IBA
IEA
ISS
(PMID:21873635) GO_Central
Ensembl
GO_Central
UniProt
Ensembl
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:49,105,822...49,128,425
Ensembl chr11:49,105,878...49,129,886
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:166,107,895...166,126,054
Ensembl chr 1:166,107,228...166,126,808
JBrowse link
G GRN granulin precursor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:95,840,906...95,860,858
Ensembl chr 6:95,840,908...95,860,858
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4879078|PMID:20920792) Ensembl
Ensembl
MGI
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 4:95,987,524...95,989,527
Ensembl chr 4:95,984,358...95,989,474
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr 9:81,837,654...81,864,215
Ensembl chr 9:81,837,667...81,864,210
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:44,636,379...44,641,536
Ensembl chr12:44,636,379...44,641,527
JBrowse link
G TMEM9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,586,487...23,600,042
Ensembl chr10:23,586,491...23,607,530
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMACR alpha-methylacyl-CoA racemase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:20,005,741...20,023,339
Ensembl chr16:19,956,366...20,023,289
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290
JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:56,657,648...56,869,920
Ensembl chr15:56,657,616...56,869,918
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:19,958,315...20,002,198
Ensembl chr16:19,956,366...20,023,289
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:295,693...313,974
Ensembl chr 8:297,007...313,972
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr 2:51,219,597...51,237,640
Ensembl chr 2:51,219,667...51,237,639
JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:62,569,813...62,918,484
Ensembl chr16:62,569,813...62,918,481
JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP3 charged multivesicular body protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:58,206,921...58,279,252
Ensembl chr 3:58,206,921...58,279,248
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA Ensembl
Ensembl
InterPro
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,898...18,342,396
JBrowse link
G MYO7A myosin VIIA involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2662763|PMID:12743369) Ensembl
Ensembl
MGI
PMID:12743369 GO_REF:0000107 MGI:2662763 NCBI chr 9:11,251,187...11,337,618
Ensembl chr 9:11,249,075...11,666,296
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3699774|PMID:11544318) Ensembl
Ensembl
MGI
PMID:11544318 GO_REF:0000107 MGI:3699774 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472
JBrowse link
G SRPX sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:3852261|PMID:19368996)
Ensembl
GO_Central
Ensembl
MGI
PMID:19368996 PMID:21873635 GO_REF:0000107 MGI:3852261 NCBI chr  X:34,075,577...34,198,462
Ensembl chr  X:34,075,579...34,198,467
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:61,640,619...61,696,819
Ensembl chr13:61,640,671...61,698,374
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290
JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr15:111,372,148...111,468,720
Ensembl chr15:111,372,173...111,467,899
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 6:78,365,697...78,376,383
Ensembl chr 6:78,302,062...78,376,220
JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:77,167,052...77,188,893
Ensembl chr11:77,167,059...77,188,898
JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in IBA
IEA
ISS
(PMID:21873635) GO_Central
GO_Central
Ensembl
UniProt
Ensembl
UniProt
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr12:44,951,989...44,956,458
Ensembl chr12:44,951,210...44,956,119
JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 9:36,341,339...36,403,690
Ensembl chr 9:36,341,339...36,403,654
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr13:71,777,422...71,886,758
Ensembl chr13:71,777,424...71,852,694
JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 9:66,635,636...66,666,034
Ensembl chr 9:66,635,638...66,666,036
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chr 2:9,947,962...10,012,713
Ensembl chr 2:9,947,925...10,012,496
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:295,693...313,974
Ensembl chr 8:297,007...313,972
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5749311|PMID:26284655) Ensembl
Ensembl
MGI
PMID:26284655 GO_REF:0000107 MGI:5749311 NCBI chr 1:126,890,464...126,998,014
Ensembl chr 1:126,902,186...127,003,397
Ensembl chr 1:126,902,186...127,003,397
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:87,363,911...87,390,371
Ensembl chr 6:87,363,912...87,390,288
JBrowse link
G MT3 metallothionein 3 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828
JBrowse link
G SH3BGRL SH3 domain binding glutamate rich protein like involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr  X:64,617,350...64,709,006 JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr  X:26,363,808...26,384,933
Ensembl chr  X:26,365,027...26,384,760
JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:54,751,570...54,796,352
Ensembl chr 8:54,751,572...54,787,886
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:295,693...313,974
Ensembl chr 8:297,007...313,972
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:30,469,003...30,496,626
Ensembl chr14:30,469,070...30,495,470
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:38,932,735...39,015,219
Ensembl chr 4:38,932,742...39,023,925
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446
JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:38,932,735...39,015,219
Ensembl chr 4:38,932,742...39,023,925
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr 9:81,837,654...81,864,215
Ensembl chr 9:81,837,667...81,864,210
JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5460923|PMID:23160154) Ensembl
Ensembl
MGI
PMID:23160154 GO_REF:0000107 MGI:5460923 NCBI chr13:31,177,604...31,180,764
Ensembl chr13:31,179,291...31,180,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17427
    cellular process 16433
      cellular component organization or biogenesis 6391
        cellular component organization 6201
          organelle organization 3519
            vacuole organization 196
              lytic vacuole organization 79
                lysosome organization 79
                  lysosomal membrane organization + 7
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 16
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 20
                  regulation of lysosome organization + 5
paths to the root