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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis



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lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IDA (PMID:15163665) BHF-UCL
BHF-UCL
PMID:15163665 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G AC001226.2 novel protein involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 Ensembl chr13:76,992,078...77,129,589 JBrowse link
G ACP2 acid phosphatase 2, lysosomal involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3522374|PMID:15604265)
(MGI:894905|PMID:9228031)
GO_Central
MGI
GO_Central
PMID:9228031 PMID:15604265 PMID:21873635 MGI:3522374 MGI:894905 NCBI chr11:47,239,302...47,248,814
Ensembl chr11:47,239,302...47,248,906
JBrowse link
G ACP3 acid phosphatase 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,298
JBrowse link
G ACP4 acid phosphatase 4 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr19:50,790,415...50,795,219
Ensembl chr19:50,790,415...50,795,219
JBrowse link
G AKTIP AKT interacting protein involved_in IMP (PMID:18799622) UniProt
UniProt
PMID:18799622 NCBI chr16:53,491,040...53,504,412
Ensembl chr16:53,491,040...53,504,411
JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1330543|PMID:9931340), (MGI:6415001|PMID:30786955) Ensembl
Ensembl
MGI
PMID:9931340 PMID:30786955 GO_REF:0000107 MGI:1330543 MGI:6415001 NCBI chr 5:78,000,522...78,294,698
Ensembl chr 5:78,000,522...78,294,762
JBrowse link
G ARSB arylsulfatase B involved_in TAS (PMID:1718978) PINC
PINC
PMID:1718978 NCBI chr 5:78,777,209...78,985,958
Ensembl chr 5:78,777,209...78,986,087
JBrowse link
G BECN1 beclin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3801567|PMID:18497889) Ensembl
Ensembl
MGI
PMID:18497889 GO_REF:0000107 MGI:3801567 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G CHMP5 charged multivesicular body protein 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3622513|PMID:16567502) MGI
Ensembl
PMID:16567502 GO_REF:0000107 MGI:3622513 NCBI chr 9:33,265,049...33,282,070
Ensembl chr 9:33,264,879...33,282,070
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within
IBA
IEA
ISS
ISO
(PMID:21873635)
(MGI:1337525|PMID:10191119), (MGI:1346962|PMID:10527801)
(MGI:3527911|PMID:15588329)
(MGI:1343910|PMID:10440905)
GO_Central
GO_Central
Ensembl
UniProt
MGI
UniProt
PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:1337525 MGI:1343910 MGI:1346962 MGI:3527911 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3512689|PMID:15459177)
GO_Central
Ensembl
GO_Central
MGI
PMID:15459177 PMID:21873635 GO_REF:0000107 MGI:3512689 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1203267|PMID:9600738), (MGI:5751614|PMID:26681805)
GO_Central
GO_Central
Ensembl
MGI
PMID:9600738 PMID:21873635 PMID:26681805 GO_REF:0000107 MGI:1203267 MGI:5751614 NCBI chr15:68,206,992...68,257,215
Ensembl chr15:68,206,992...68,257,211
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1333651|PMID:10087069), (MGI:65559|PMID:8144516), (MGI:66707|PMID:8160780), (MGI:71226|PMID:7613514) Ensembl
Ensembl
MGI
PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 MGI:1333651 MGI:65559 MGI:66707 MGI:71226 NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711
JBrowse link
G CLVS1 clavesin 1 involved_in ISS
IBA
IEA
(PMID:21873635) UniProt
GO_Central
Ensembl
InterPro
UniProt
InterPro
GO_Central
PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:60,964,848...61,501,629
Ensembl chr 8:61,057,158...61,501,645
JBrowse link
G CLVS2 clavesin 2 involved_in IBA
IEA
ISS
(PMID:21873635) GO_Central
InterPro
GO_Central
UniProt
UniProt
PMID:21873635 GO_REF:0000002 GO_REF:0000024 NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925
JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IMP
IBA
(PMID:18799622)
(PMID:21873635)
UniProt
UniProt
GO_Central
GO_Central
PMID:18799622 PMID:21873635 NCBI chr11:6,211,345...6,234,636
Ensembl chr11:6,211,345...6,234,711
JBrowse link
G GAA alpha glucosidase involved_in
acts_upstream_of_or_within
IMP
IEA
IBA
ISO
(PMID:7717400)
(PMID:21873635)
(MGI:1275872|PMID:9668092), (MGI:3618942|PMID:15169761)
(MGI:1195358|PMID:9384603), (MGI:1346721|PMID:10547605), (MGI:2136118|PMID:11328962), (MGI:3664400|PMID:12115977)
BHF-UCL
Ensembl
GO_Central
BHF-UCL
MGI
GO_Central
PMID:7717400 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 More... GO_REF:0000107 MGI:1195358 MGI:1275872 MGI:1346721 MGI:2136118 MGI:3618942 MGI:3664400 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,556...80,119,881
JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IMP
IEA
(PMID:27378698) UniProt
UniProt
Ensembl
PMID:27378698 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699
JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IMP (PMID:21719679) UniProt
UniProt
PMID:21719679 NCBI chr12:101,745,499...101,830,959
Ensembl chr12:101,745,499...101,830,959
JBrowse link
G GRN granulin precursor involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G HEXA hexosaminidase subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:77946|PMID:8747922)
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
(MGI:1097747|PMID:9302266), (MGI:1271008|PMID:9645704), (MGI:1352198|PMID:10591619), (MGI:3033296|PMID:14972652)
(MGI:69059|PMID:7937929), (MGI:86923|PMID:9103204)
MGI
Ensembl
PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 MGI:1097747 MGI:1271008 MGI:1352198 MGI:3033296 MGI:69059 MGI:77946 MGI:83770 MGI:86923 MGI:894634 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,924...72,376,420
JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
(MGI:1271008|PMID:9645704), (MGI:78473|PMID:8789434)
Ensembl
Ensembl
MGI
PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 MGI:1271008 MGI:78473 MGI:83770 MGI:894634 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in IMP (PMID:18799622) UniProt
UniProt
PMID:18799622 NCBI chr 1:59,814,949...59,876,322
Ensembl chr 1:59,814,786...59,876,322
JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IMP (PMID:18799622) UniProt
UniProt
PMID:18799622 NCBI chr19:12,763,003...12,792,350
Ensembl chr19:12,763,003...12,872,740
JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in IMP (PMID:18799622) UniProt
UniProt
PMID:18799622 NCBI chr 8:42,896,978...43,030,535
Ensembl chr 8:42,896,946...43,030,535
JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 involved_in
acts_upstream_of_or_within
TAS
ISO
(PMID:10625677)
(MGI:6415001|PMID:30786955)
PINC
PINC
MGI
PMID:10625677 PMID:30786955 MGI:6415001 NCBI chr10:98,413,948...98,446,935
Ensembl chr10:98,410,939...98,446,963
JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IDA (PMID:12663659) UniProt
UniProt
PMID:12663659 NCBI chr22:26,443,109...26,483,863
Ensembl chr22:26,443,107...26,483,931
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (MGI:86916|PMID:9097952)
(MGI:4414887|PMID:19751987)
MGI PMID:9097952 PMID:19751987 MGI:4414887 MGI:86916 NCBI chr 4:986,997...1,008,351
Ensembl chr 4:986,997...1,004,564
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA
ISS
InterPro
Ensembl
UniProt
InterPro
UniProt
GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr11:72,097,292...72,103,297
Ensembl chr11:72,085,895...72,103,297
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IMP (PMID:25416817) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:25416817 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G LYST lysosomal trafficking regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:53816|PMID:4697831), (MGI:53992|PMID:1113502), (MGI:55104|PMID:6170520), (MGI:56449|PMID:4031470)
(MGI:1099544|PMID:9368050)
InterPro
InterPro
MGI
PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 GO_REF:0000002 MGI:1099544 MGI:53816 MGI:53992 MGI:55104 MGI:56449 NCBI chr 1:235,661,031...235,883,713
Ensembl chr 1:235,661,041...235,883,724
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IMP (PMID:21719679) UniProt
UniProt
PMID:21719679 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942
JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5751614|PMID:26681805)
(MGI:5575728|PMID:24423645)
Ensembl
Ensembl
MGI
PMID:24423645 PMID:26681805 GO_REF:0000107 MGI:5575728 MGI:5751614 NCBI chr 4:127,917,732...127,965,963
Ensembl chr 4:127,917,799...127,966,034
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IDA (PMID:22692423) UniProt
UniProt
PMID:22692423 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MYO7A myosin VIIA involved_in IDA (PMID:16001398) UniProt
UniProt
PMID:16001398 NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241
JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3769195|PMID:17712420) Ensembl
Ensembl
MGI
PMID:17712420 GO_REF:0000107 MGI:3769195 NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449
JBrowse link
G NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase involved_in TAS (PMID:10551838) PINC
PINC
PMID:10551838 NCBI chr16:5,024,844...5,033,935
Ensembl chr16:5,024,844...5,034,141
JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within IDA (PMID:25365221) MGI PMID:25365221 NCBI chr 1:151,291,797...151,327,715
Ensembl chr 1:151,291,797...151,327,715
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3654230|PMID:16542649)
(MGI:3612221|PMID:16368712)
MGI
Ensembl
PMID:16368712 PMID:16542649 GO_REF:0000107 MGI:3612221 MGI:3654230 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:4879078|PMID:20920792)
GO_Central
GO_Central
Ensembl
MGI
PMID:20920792 PMID:21873635 GO_REF:0000107 MGI:4879078 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within
IEA
IDA
(PMID:25365221) Ensembl
MGI
PMID:25365221 GO_REF:0000107 NCBI chr15:44,562,696...44,663,662
Ensembl chr15:44,554,818...44,663,688
JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within
IDA
ISO
IMP
(PMID:22692423)
(PMID:22692423), (PMID:35662396)
(MGI:6433162|PMID:31637311)
(PMID:23434374)
UniProt
UniProt
MGI
PMID:22692423 PMID:23434374 PMID:31637311 PMID:35662396 MGI:6433162 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259
JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:5588048|PMID:25066864)
GO_Central
GO_Central
Ensembl
MGI
PMID:21873635 PMID:25066864 GO_REF:0000107 MGI:5588048 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367
JBrowse link
G TPCN2 two pore segment channel 2 involved_in IGI (PMID:25416817) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:25416817 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316
JBrowse link
G TPP1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:3522013|PMID:15483130) UniProt
UniProt
Ensembl
MGI
PMID:15483130 GO_REF:0000024 GO_REF:0000107 MGI:3522013 NCBI chr11:6,612,768...6,619,422
Ensembl chr11:6,612,768...6,619,448
JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IDA
IBA
(PMID:18799622)
(PMID:21873635)
UniProt
UniProt
GO_Central
GO_Central
PMID:18799622 PMID:21873635 NCBI chr15:40,894,450...40,903,975
Ensembl chr15:40,894,450...40,903,975
JBrowse link
G VPS35 VPS35 retromer complex component involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518
JBrowse link
G WASHC5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6199426|PMID:30061306) Ensembl
Ensembl
MGI
PMID:30061306 GO_REF:0000107 MGI:6199426 NCBI chr 8:125,024,260...125,091,792
Ensembl chr 8:125,024,260...125,091,819
JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within IDA (PMID:25365221) MGI PMID:25365221 NCBI chr14:67,728,892...67,816,590
Ensembl chr14:67,727,374...67,816,590
JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 involved_in IMP (PMID:23434374) UniProt
UniProt
PMID:23434374 NCBI chr 6:28,349,878...28,369,172
Ensembl chr 6:28,349,947...28,369,172
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IMP
IC
(PMID:32276428)
(PMID:32001091), (PMID:33065002)
UniProt
ComplexPortal
UniProt
PMID:32001091 PMID:32276428 PMID:33065002 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in IC (PMID:33065002) ComplexPortal PMID:33065002 NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582
JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295
JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,747,033...113,812,056
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IMP (PMID:28296633) UniProt
UniProt
PMID:28296633 NCBI chr 2:130,337,933...130,342,681
Ensembl chr 2:130,337,933...130,342,699
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IBA
IMP
(PMID:21873635)
(PMID:11722572)
GO_Central
GO_Central
UniProt
UniProt
PMID:11722572 PMID:21873635 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in IMP (PMID:11722572) UniProt
UniProt
PMID:11722572 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IMP (PMID:11722572) UniProt
UniProt
PMID:11722572 NCBI chr15:68,206,992...68,257,215
Ensembl chr15:68,206,992...68,257,211
JBrowse link
G GRN granulin precursor involved_in IMP (PMID:28073925) UniProt
UniProt
PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IMP (PMID:11722572) UniProt
UniProt
PMID:11722572 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260
JBrowse link
G RNASEK ribonuclease K involved_in IC (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4879078|PMID:20920792) Ensembl
Ensembl
MGI
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in IC (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6101836|PMID:28728022) MGI
Ensembl
Ensembl
PMID:28728022 GO_REF:0000107 MGI:6101836 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IMP (PMID:28296633) UniProt
UniProt
PMID:28296633 NCBI chr17:28,357,647...28,363,683
Ensembl chr17:28,357,642...28,363,683
JBrowse link
G TMEM9 transmembrane protein 9 involved_in IDA (PMID:30374053) UniProt
UniProt
PMID:30374053 NCBI chr 1:201,134,772...201,171,558
Ensembl chr 1:201,134,772...201,171,574
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IDA (PMID:10924275) UniProt
UniProt
PMID:10924275 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IDA (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chr15:27,719,008...28,099,315
Ensembl chr15:27,754,875...28,099,315
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in ISS
IEA
IDA
(PMID:32966160) UniProt
Ensembl
PMID:32966160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:33,944,623...33,984,693
Ensembl chr 5:33,944,623...33,984,693
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IDA (PMID:35333573), (PMID:35750034) UniProt PMID:35333573 PMID:35750034 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,708...228,099,212
JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in IDA (PMID:32172343) UniProt
UniProt
PMID:32172343 NCBI chr 5:160,563,120...160,929,360
Ensembl chr 5:160,563,120...160,852,214
JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP1A charged multivesicular body protein 1A involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr16:89,644,435...89,657,708
Ensembl chr16:89,640,816...89,657,738
JBrowse link
G CHMP1B charged multivesicular body protein 1B involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr18:11,851,413...11,854,444
Ensembl chr18:11,851,413...11,854,444
JBrowse link
G CHMP2A charged multivesicular body protein 2A involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr19:58,551,566...58,555,105
Ensembl chr19:58,551,452...58,555,105
JBrowse link
G CHMP2B charged multivesicular body protein 2B involved_in TAS
IC
(PMID:21118109)
(PMID:16505166)
ParkinsonsUK-UCL
ComplexPortal
ParkinsonsUK-UCL
PMID:16505166 PMID:21118109 NCBI chr 3:87,227,309...87,255,556
Ensembl chr 3:87,227,271...87,255,556
JBrowse link
G CHMP3 charged multivesicular body protein 3 involved_in IMP
IC
(PMID:16554368)
(PMID:16505166)
ParkinsonsUK-UCL
ComplexPortal
ParkinsonsUK-UCL
PMID:16505166 PMID:16554368 NCBI chr 2:86,503,430...86,563,443
Ensembl chr 2:86,503,430...86,563,479
JBrowse link
G CHMP4A charged multivesicular body protein 4A involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr14:24,209,615...24,213,488
Ensembl chr14:24,209,615...24,213,830
JBrowse link
G CHMP4B charged multivesicular body protein 4B involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr20:33,811,348...33,854,366
Ensembl chr20:33,811,348...33,854,366
JBrowse link
G CHMP4C charged multivesicular body protein 4C involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr 8:81,732,448...81,759,515
Ensembl chr 8:81,732,448...81,759,515
JBrowse link
G CHMP5 charged multivesicular body protein 5 involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr 9:33,265,049...33,282,070
Ensembl chr 9:33,264,879...33,282,070
JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr17:80,991,841...81,000,133
Ensembl chr17:80,991,598...81,009,517
JBrowse link
G CHMP7 charged multivesicular body protein 7 involved_in IC (PMID:16505166) ComplexPortal PMID:16505166 NCBI chr 8:23,243,637...23,261,999
Ensembl chr 8:23,243,637...23,262,000
JBrowse link
G RNF103-CHMP3 RNF103-CHMP3 readthrough involved_in IMP
IC
(PMID:16554368)
(PMID:16505166)
ParkinsonsUK-UCL
ComplexPortal
ParkinsonsUK-UCL
PMID:16505166 PMID:16554368 NCBI chr 2:86,503,430...86,721,122
Ensembl chr 2:86,505,668...86,721,122
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 involved_in IEA
ISO
Ensembl
RGD
Ensembl
PMID:25561470 GO_REF:0000107 RGD:11561937 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA
IMP
(PMID:12132654) InterPro
UniProt
InterPro
UniProt
PMID:12132654 GO_REF:0000002 NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076
JBrowse link
G MYO7A myosin VIIA involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2662763|PMID:12743369) Ensembl
Ensembl
MGI
PMID:12743369 GO_REF:0000107 MGI:2662763 NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3699774|PMID:11544318) MGI
Ensembl
Ensembl
PMID:11544318 GO_REF:0000107 MGI:3699774 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G SRPX sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:3852261|PMID:19368996)
Ensembl
GO_Central
Ensembl
MGI
PMID:19368996 PMID:21873635 GO_REF:0000107 MGI:3852261 NCBI chr  X:38,149,339...38,220,871
Ensembl chr  X:38,149,336...38,220,924
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB14 RAB14, member RAS oncogene family involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 9:121,178,133...121,201,869
Ensembl chr 9:121,178,133...121,223,014
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IMP (PMID:21802320) UniProt
UniProt
PMID:21802320 NCBI chr 3:5,122,292...5,180,911
Ensembl chr 3:5,122,249...5,180,911
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IDA
IBA
IEA
(PMID:28779020)
(PMID:21873635)
UniProt
GO_Central
UniProt
Ensembl
PMID:21873635 PMID:28779020 GO_REF:0000107 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911
JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IMP (PMID:21255211) UniProt
UniProt
PMID:21255211 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722
JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in IBA
IMP
(PMID:21873635)
(PMID:21255211)
GO_Central
GO_Central
UniProt
UniProt
PMID:21255211 PMID:21873635 NCBI chr17:28,714,281...28,718,428
Ensembl chr17:28,714,281...28,718,429
JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IMP
IBA
(PMID:21255211)
(PMID:21873635)
UniProt
GO_Central
UniProt
PMID:21255211 PMID:21873635 NCBI chr11:107,928,448...107,963,482
Ensembl chr11:107,928,448...107,963,482
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in IMP
IBA
(PMID:21255211)
(PMID:21873635)
UniProt
GO_Central
UniProt
GO_Central
PMID:21255211 PMID:21873635 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr11:61,513,714...61,588,387
Ensembl chr11:61,513,714...61,581,148
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
G VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog involved_in IC (PMID:27555442) ComplexPortal PMID:27555442 NCBI chr14:77,426,675...77,457,601
Ensembl chr14:77,426,675...77,457,952
JBrowse link
G VPS33B VPS33B late endosome and lysosome associated involved_in IC (PMID:27555442) ComplexPortal PMID:27555442 NCBI chr15:90,998,416...91,022,621
Ensembl chr15:90,998,673...91,022,603
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5749311|PMID:26284655) Ensembl
Ensembl
MGI
PMID:26284655 GO_REF:0000107 MGI:5749311 NCBI chr15:44,562,696...44,663,662
Ensembl chr15:44,554,818...44,663,688
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IDA (PMID:19787053) ARUK-UCL
ARUK-UCL
PMID:19787053 NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774
JBrowse link
G MT3 metallothionein 3 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IDA (PMID:28073925) UniProt
UniProt
PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IMP (PMID:22012985) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:22012985 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IDA
IBA
(PMID:31001245)
(PMID:21873635)
UniProt
UniProt
GO_Central
GO_Central
PMID:21873635 PMID:31001245 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766
JBrowse link
G TMEM165 transmembrane protein 165 involved_in IMP (PMID:23569283) UniProt
UniProt
PMID:23569283 NCBI chr 4:55,395,957...55,453,397
Ensembl chr 4:55,395,957...55,453,397
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IMP (PMID:28013294) UniProt
UniProt
PMID:28013294 NCBI chr12:122,229,564...122,266,494
Ensembl chr12:122,229,564...122,266,494
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IMP (PMID:26280656) UniProt
UniProt
PMID:26280656 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IMP (PMID:26280656) UniProt
UniProt
PMID:26280656 NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013
JBrowse link
G SCARB2 scavenger receptor class B member 2 involved_in TAS (PMID:12356916) ParkinsonsUK-UCL
ParkinsonsUK-UCL
PMID:12356916 NCBI chr 4:76,158,737...76,234,532
Ensembl chr 4:76,158,737...76,234,536
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6101836|PMID:28728022) MGI
Ensembl
Ensembl
PMID:28728022 GO_REF:0000107 MGI:6101836 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367
JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5460923|PMID:23160154) Ensembl
Ensembl
MGI
PMID:23160154 GO_REF:0000107 MGI:5460923 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19753
    cellular process 18239
      cellular component organization or biogenesis 7360
        cellular component organization 7155
          organelle organization 3905
            vacuole organization 228
              lytic vacuole organization 105
                lysosome organization 105
                  lysosomal membrane organization + 18
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 19
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 28
                  regulation of lysosome organization + 6
paths to the root