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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis



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lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:60,761,669...60,869,753
Ensembl chr11:60,761,655...60,890,496
JBrowse link
G ACP2 acid phosphatase 2, lysosomal involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3522374|PMID:15604265)
(MGI:894905|PMID:9228031)
GO_Central
MGI
PMID:9228031 PMID:15604265 PMID:21873635 MGI:3522374 MGI:894905 NCBI chr18:42,346,207...42,356,447
Ensembl chr18:42,345,608...42,354,352
JBrowse link
G ACP3 acid phosphatase 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr23:29,294,641...29,353,970
Ensembl chr23:29,294,843...29,343,499
JBrowse link
G ACP4 acid phosphatase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:106,051,901...106,056,137
Ensembl chr 1:106,051,901...106,056,137
JBrowse link
G AKTIP AKT interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:62,253,005...62,263,918
Ensembl chr 2:62,254,320...62,263,337
JBrowse link
G ANAPC15 anaphase promoting complex subunit 15 involved_in IEA InterPro GO_REF:0000002 NCBI chr21:25,971,680...25,975,556
Ensembl chr21:25,972,458...25,975,558
JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1330543|PMID:9931340), (MGI:6415001|PMID:30786955) MGI
Ensembl
PMID:9931340 PMID:30786955 GO_REF:0000107 MGI:1330543 MGI:6415001 NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258
JBrowse link
G BECN1 beclin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3801567|PMID:18497889) MGI
Ensembl
Ensembl
PMID:18497889 GO_REF:0000107 MGI:3801567 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
G CHMP5 charged multivesicular body protein 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3622513|PMID:16567502) Ensembl
MGI
PMID:16567502 GO_REF:0000107 MGI:3622513 NCBI chr11:50,363,488...50,376,081 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1337525|PMID:10191119), (MGI:1346962|PMID:10527801)
(MGI:3527911|PMID:15588329)
(MGI:1343910|PMID:10440905)
GO_Central
Ensembl
MGI
PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 PMID:21873635 GO_REF:0000107 MGI:1337525 MGI:1343910 MGI:1346962 MGI:3527911 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3512689|PMID:15459177)
GO_Central
Ensembl
GO_Central
MGI
PMID:15459177 PMID:21873635 GO_REF:0000107 MGI:3512689 NCBI chr22:30,568,572...30,575,890
Ensembl chr22:30,568,572...30,575,890
JBrowse link
G CLN6 CLN6 transmembrane ER protein acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
(MGI:1203267|PMID:9600738), (MGI:5751614|PMID:26681805)
(PMID:21873635)
MGI
Ensembl
GO_Central
PMID:9600738 PMID:21873635 PMID:26681805 GO_REF:0000107 MGI:1203267 MGI:5751614 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO (MGI:1333651|PMID:10087069), (MGI:65559|PMID:8144516), (MGI:66707|PMID:8160780), (MGI:71226|PMID:7613514) MGI PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 MGI:1333651 MGI:65559 MGI:66707 MGI:71226 NCBI chr37:30,863,098...30,885,831
Ensembl chr37:30,867,479...30,884,895
JBrowse link
G CLVS1 clavesin 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr29:11,638,550...11,811,853
Ensembl chr29:11,638,024...11,812,396
JBrowse link
G CLVS2 clavesin 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 1:62,217,473...62,286,853
Ensembl chr 1:62,217,837...62,282,449
JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:29,547,361...29,570,900
Ensembl chr21:29,547,522...29,566,536
JBrowse link
G GAA alpha glucosidase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:1275872|PMID:9668092), (MGI:3618942|PMID:15169761)
(MGI:1195358|PMID:9384603), (MGI:1346721|PMID:10547605), (MGI:2136118|PMID:11328962), (MGI:3664400|PMID:12115977)
GO_Central
MGI
PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 More... MGI:1195358 MGI:1275872 MGI:1346721 MGI:2136118 MGI:3618942 MGI:3664400 NCBI chr 9:1,601,092...1,615,582
Ensembl chr 9:1,601,121...1,656,597
JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864
JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:40,659,108...40,724,498
Ensembl chr15:40,631,279...40,704,365
JBrowse link
G GRN granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268
JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:69059|PMID:7937929), (MGI:86923|PMID:9103204)
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
(MGI:77946|PMID:8747922)
(MGI:1097747|PMID:9302266), (MGI:1271008|PMID:9645704), (MGI:1352198|PMID:10591619), (MGI:3033296|PMID:14972652)
Ensembl
Ensembl
MGI
PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 MGI:1097747 MGI:1271008 MGI:1352198 MGI:3033296 MGI:69059 MGI:77946 MGI:83770 MGI:86923 MGI:894634 NCBI chr30:35,836,788...35,862,525 JBrowse link
G HEXB hexosaminidase subunit beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1271008|PMID:9645704), (MGI:78473|PMID:8789434)
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
MGI
Ensembl
PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 MGI:1271008 MGI:78473 MGI:83770 MGI:894634 NCBI chr 2:57,221,809...57,248,432
Ensembl chr 2:57,222,186...57,248,417
JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:49,994,930...50,060,513
Ensembl chr 5:49,998,241...50,060,525
JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,367,450...49,383,109
Ensembl chr20:49,367,876...49,382,813
JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in ISO (PMID:18799622) UniProt PMID:18799622 NCBI chr16:22,791,198...22,940,168
Ensembl chr16:22,784,267...22,901,991
JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (MGI:6415001|PMID:30786955) MGI PMID:30786955 MGI:6415001 NCBI chr28:11,547,457...11,572,248
Ensembl chr28:11,547,741...11,571,613
JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in ISO (PMID:12663659) UniProt PMID:12663659 NCBI chr26:20,131,658...20,157,532
Ensembl chr26:19,933,281...20,157,058
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (MGI:86916|PMID:9097952)
(MGI:4414887|PMID:19751987)
MGI PMID:9097952 PMID:19751987 MGI:4414887 MGI:86916 NCBI chr 3:91,517,225...91,534,593
Ensembl chr 3:91,522,035...91,534,593
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl
Ensembl
InterPro
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr21:25,981,170...25,986,942
Ensembl chr21:25,981,254...25,996,432
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870
JBrowse link
G LYST lysosomal trafficking regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1099544|PMID:9368050)
(MGI:53816|PMID:4697831), (MGI:53992|PMID:1113502), (MGI:55104|PMID:6170520), (MGI:56449|PMID:4031470)
MGI
InterPro
InterPro
PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 GO_REF:0000002 MGI:1099544 MGI:53816 MGI:53992 MGI:55104 MGI:56449 NCBI chr 4:4,106,869...4,296,042
Ensembl chr 4:4,089,837...4,294,593
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in ISO (PMID:21719679) UniProt PMID:21719679 NCBI chr 5:68,228,176...68,281,175
Ensembl chr 5:68,228,238...68,280,515
JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5575728|PMID:24423645)
(MGI:5751614|PMID:26681805)
Ensembl
Ensembl
MGI
PMID:24423645 PMID:26681805 GO_REF:0000107 MGI:5575728 MGI:5751614 NCBI chr19:12,905,336...13,030,901
Ensembl chr19:12,982,394...13,020,083
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G MYO7A myosin VIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:21,539,735...21,624,063
Ensembl chr21:21,539,785...21,624,279
JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3769195|PMID:17712420) Ensembl
Ensembl
MGI
PMID:17712420 GO_REF:0000107 MGI:3769195 NCBI chr 9:20,407,296...20,414,094
Ensembl chr 9:20,407,281...20,414,056
JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within ISO (PMID:25365221) MGI PMID:25365221 NCBI chr17:60,359,545...60,386,093
Ensembl chr17:60,360,236...60,384,778
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3612221|PMID:16368712)
(MGI:3654230|PMID:16542649)
MGI
Ensembl
PMID:16368712 PMID:16542649 GO_REF:0000107 MGI:3612221 MGI:3654230 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4879078|PMID:20920792)
GO_Central
MGI
PMID:20920792 PMID:21873635 MGI:4879078 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323
JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5749311|PMID:26284655)
(PMID:25365221)
(MGI:6141536|PMID:28237315), (MGI:6433162|PMID:31637311)
MGI
Ensembl
PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 GO_REF:0000107 MGI:5749311 MGI:6141536 MGI:6433162 NCBI chr30:11,233,709...11,305,454
Ensembl chr30:11,233,718...11,305,485
JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6433162|PMID:31637311) Ensembl
MGI
PMID:31637311 GO_REF:0000107 MGI:6433162 NCBI chr12:10,367,979...10,423,478
Ensembl chr12:10,368,599...10,452,619
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:5588048|PMID:25066864)
(PMID:21873635)
MGI
GO_Central
PMID:21873635 PMID:25066864 MGI:5588048 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333
JBrowse link
G TPCN2 two pore segment channel 2 involved_in ISO (PMID:25416817) ParkinsonsUK-UCL PMID:25416817 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564
JBrowse link
G TPP1 tripeptidyl peptidase 1 acts_upstream_of_or_within ISO (MGI:3522013|PMID:15483130) MGI PMID:15483130 MGI:3522013 NCBI chr21:29,921,764...29,926,974
Ensembl chr21:29,921,764...29,926,986
JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr30:8,027,877...8,036,773
Ensembl chr30:8,027,128...8,036,153
JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr15:8,428,073...8,454,601
Ensembl chr15:8,428,172...8,454,049
JBrowse link
G WASHC5 WASH complex subunit 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6199426|PMID:30061306) MGI
Ensembl
PMID:30061306 GO_REF:0000107 MGI:6199426 NCBI chr13:23,019,422...23,078,073
Ensembl chr13:23,019,636...23,078,280
JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within ISO (PMID:25365221) MGI PMID:25365221 NCBI chr 8:41,714,654...41,777,996
Ensembl chr 8:41,715,485...41,777,422
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:19,027,014...19,031,467
Ensembl chr25:19,027,342...19,030,887
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA
IBA
(PMID:21873635) UniProt
Ensembl
UniProt
GO_Central
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr22:30,568,572...30,575,890
Ensembl chr22:30,568,572...30,575,890
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240
JBrowse link
G GRN granulin precursor involved_in ISO (PMID:28073925) UniProt PMID:28073925 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4879078|PMID:20920792) Ensembl
MGI
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:42,607,688...42,614,776
Ensembl chr 9:42,607,733...42,611,445
JBrowse link
G TMEM9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chr 7:2,069,017...2,087,961 JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA
UniProt
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,361,825...32,713,631
Ensembl chr 3:32,361,517...32,713,572
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in ISO (PMID:32966160) UniProt PMID:32966160 NCBI chr 4:73,838,684...73,868,222
Ensembl chr 4:73,815,291...73,867,437
JBrowse link
G TMEM175 transmembrane protein 175 involved_in ISO (PMID:35333573), (PMID:35750034) UniProt PMID:35333573 PMID:35750034 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr14:835,476...836,424
Ensembl chr14:835,476...836,424
JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in ISO (PMID:32172343) UniProt PMID:32172343 NCBI chr 4:49,856,489...50,163,033
Ensembl chr 4:49,912,397...50,161,319
JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) ParkinsonsUK-UCL PMID:16554368 NCBI chr17:38,600,793...38,658,368 JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA Ensembl
InterPro
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818
JBrowse link
G MYO7A myosin VIIA acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2662763|PMID:12743369) MGI
Ensembl
Ensembl
PMID:12743369 GO_REF:0000107 MGI:2662763 NCBI chr21:21,539,735...21,624,063
Ensembl chr21:21,539,785...21,624,279
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3699774|PMID:11544318) MGI
Ensembl
PMID:11544318 GO_REF:0000107 MGI:3699774 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G SRPX sushi repeat containing protein X-linked acts_upstream_of_or_within ISO (MGI:3852261|PMID:19368996) MGI PMID:19368996 MGI:3852261 NCBI chr  X:32,905,380...33,017,642
Ensembl chr  X:32,745,020...33,330,841
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB14 RAB14, member RAS oncogene family involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:74,157,497...74,172,817
Ensembl chr11:74,159,414...74,172,810
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS
Ensembl
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr20:12,479,680...12,525,330
Ensembl chr20:12,481,860...12,525,499
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA
ISS
Ensembl
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr37:16,537,095...16,620,427
Ensembl chr37:16,541,562...16,619,554
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983
JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr22:58,825,147...58,853,921
Ensembl chr22:58,825,667...58,853,667
JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:42,909,843...42,913,935
Ensembl chr 9:42,910,011...42,913,985
JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:24,516,541...24,546,743
Ensembl chr 5:24,519,240...24,546,606
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISS
IBA
(PMID:21873635) UniProt
GO_Central
UniProt
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr20:2,704,716...2,776,518
Ensembl chr20:2,704,752...2,826,636
JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr38:2,333,939...2,359,531
Ensembl chr38:2,335,535...2,359,469
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5749311|PMID:26284655) MGI
Ensembl
PMID:26284655 GO_REF:0000107 MGI:5749311 NCBI chr30:11,233,709...11,305,454
Ensembl chr30:11,233,718...11,305,485
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073
JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT3 metallothionein 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in ISO (MGI:5905514|PMID:28073925)
(PMID:28073925)
UniProt PMID:28073925 MGI:5905514 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:31001245) UniProt PMID:31001245 NCBI chr  X:25,664,361...25,679,044 JBrowse link
G TMEM165 transmembrane protein 165 involved_in ISO (PMID:23569283) UniProt PMID:23569283 NCBI chr13:47,658,408...47,683,519
Ensembl chr13:47,658,330...47,682,866
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,090,669...7,119,913 JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chr13:41,134...127,399
Ensembl chr13:41,121...127,182
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268
JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in ISO (PMID:26280656) UniProt PMID:26280656 NCBI chr13:41,134...127,399
Ensembl chr13:41,121...127,182
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333
JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5460923|PMID:23160154) MGI
Ensembl
Ensembl
PMID:23160154 GO_REF:0000107 MGI:5460923 NCBI chr20:40,624,845...40,626,840
Ensembl chr20:40,624,891...40,626,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17341
    cellular process 16317
      cellular component organization or biogenesis 6441
        cellular component organization 6245
          organelle organization 3517
            vacuole organization 203
              lytic vacuole organization 80
                lysosome organization 80
                  lysosomal membrane organization + 8
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 17
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 18
                  regulation of lysosome organization + 5
paths to the root