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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis



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lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188
JBrowse link
G ACP2 acid phosphatase 2, lysosomal acts_upstream_of_or_within ISO (MGI:894905|PMID:9228031)
(MGI:3522374|PMID:15604265)
MGI PMID:9228031 PMID:15604265 MGI:3522374 MGI:894905 NCBI chr11:47,185,611...47,195,174
Ensembl chr11:47,738,845...47,748,450
JBrowse link
G AKTIP AKT interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:33,731,652...33,743,571
Ensembl chr16:52,815,559...52,827,750
JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1330543|PMID:9931340), (MGI:6415001|PMID:30786955) MGI
Ensembl
PMID:9931340 PMID:30786955 GO_REF:0000107 MGI:1330543 MGI:6415001 NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205
JBrowse link
G BECN1 beclin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3801567|PMID:18497889) MGI
Ensembl
PMID:18497889 GO_REF:0000107 MGI:3801567 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G CHMP5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO (MGI:3622513|PMID:16567502) MGI PMID:16567502 MGI:3622513 NCBI chr 9:33,043,148...33,059,564
Ensembl chr 9:33,851,377...33,867,942
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO (MGI:3527911|PMID:15588329)
(MGI:1337525|PMID:10191119), (MGI:1346962|PMID:10527801)
(MGI:1343910|PMID:10440905)
MGI PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 MGI:1337525 MGI:1343910 MGI:1346962 MGI:3527911
G CLN5 CLN5 intracellular trafficking protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3512689|PMID:15459177) MGI
Ensembl
PMID:15459177 GO_REF:0000107 MGI:3512689 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759
JBrowse link
G CLN6 CLN6 transmembrane ER protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1203267|PMID:9600738), (MGI:5751614|PMID:26681805) MGI
Ensembl
PMID:9600738 PMID:26681805 GO_REF:0000107 MGI:1203267 MGI:5751614 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1333651|PMID:10087069), (MGI:65559|PMID:8144516), (MGI:66707|PMID:8160780), (MGI:71226|PMID:7613514) MGI
Ensembl
PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 GO_REF:0000107 MGI:1333651 MGI:65559 MGI:66707 MGI:71226 NCBI chr 8:5,587,875...5,606,883
Ensembl chr 8:1,658,694...1,700,754
JBrowse link
G CLVS1 clavesin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:57,703,459...57,921,997
Ensembl chr 8:59,252,291...59,630,784
JBrowse link
G CLVS2 clavesin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:120,784,849...120,858,655
Ensembl chr 6:124,907,667...124,975,839
JBrowse link
G FHIP1B FHF complex subunit HOOK interacting protein 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,345,227...6,368,675
Ensembl chr11:6,027,300...6,050,850
JBrowse link
G GAA alpha glucosidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1275872|PMID:9668092), (MGI:3618942|PMID:15169761)
(MGI:1195358|PMID:9384603), (MGI:1346721|PMID:10547605), (MGI:2136118|PMID:11328962), (MGI:3664400|PMID:12115977)
MGI
Ensembl
PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 More... GO_REF:0000107 MGI:1195358 MGI:1275872 MGI:1346721 MGI:2136118 MGI:3618942 MGI:3664400 NCBI chr17:74,188,296...74,206,593
Ensembl chr17:79,723,699...79,741,839
JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:99,328,026...99,418,151
Ensembl chr12:102,729,615...102,816,560
JBrowse link
G GRN granulin precursor involved_in ISO (MGI:6274951|PMID:27789271) UniProt PMID:27789271 MGI:6274951 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
G HEXB hexosaminidase subunit beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1271008|PMID:9645704), (MGI:78473|PMID:8789434)
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
MGI
Ensembl
PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 MGI:1271008 MGI:78473 MGI:83770 MGI:894634 NCBI chr 5:40,589,448...40,625,176
Ensembl chr 5:41,199,681...41,232,693
JBrowse link
G HOOK1 hook microtubule tethering protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:59,072,565...59,134,191
Ensembl chr 1:60,777,769...60,839,384
JBrowse link
G HOOK2 hook microtubule tethering protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,325,578...12,340,754
Ensembl chr19:13,070,289...13,082,612
JBrowse link
G HOOK3 hook microtubule tethering protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,145,427...42,278,727
Ensembl chr 8:39,595,762...39,711,043
JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (MGI:6415001|PMID:30786955) MGI PMID:30786955 MGI:6415001 NCBI chr10:95,030,626...95,061,415
Ensembl chr10:98,526,113...98,552,922
JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:7,513,397...7,545,782
Ensembl chr22:25,236,360...25,268,699
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (MGI:86916|PMID:9097952)
(MGI:4414887|PMID:19751987)
MGI PMID:9097952 PMID:19751987 MGI:4414887 MGI:86916 NCBI chr 4:1,102,288...1,120,973
Ensembl chr 4:1,020,582...1,037,877
JBrowse link
G LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr11:67,177,580...67,183,631
Ensembl chr11:70,390,141...70,407,246
JBrowse link
G LOC100986229 CUGBP Elav-like family member 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1097747|PMID:9302266), (MGI:1271008|PMID:9645704), (MGI:1352198|PMID:10591619), (MGI:3033296|PMID:14972652)
(MGI:77946|PMID:8747922)
(MGI:69059|PMID:7937929), (MGI:86923|PMID:9103204)
(MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
MGI
Ensembl
PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... GO_REF:0000107 MGI:1097747 MGI:1271008 MGI:1352198 MGI:3033296 MGI:69059 MGI:77946 MGI:83770 MGI:86923 MGI:894634 NCBI chr15:51,235,123...51,326,832
Ensembl chr15:70,057,943...70,090,688
Ensembl chr15:70,057,943...70,090,688
JBrowse link
G LOC100986882 lysosomal acid glucosylceramidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851
JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G LYST lysosomal trafficking regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1099544|PMID:9368050)
(MGI:53816|PMID:4697831), (MGI:53992|PMID:1113502), (MGI:55104|PMID:6170520), (MGI:56449|PMID:4031470)
MGI
InterPro
PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 GO_REF:0000002 MGI:1099544 MGI:53816 MGI:53992 MGI:55104 MGI:56449 NCBI chr 1:211,229,800...211,451,947
Ensembl chr 1:216,231,824...216,436,293
JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,719,971...64,783,119
Ensembl chr16:84,063,508...84,126,000
JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5575728|PMID:24423645)
(MGI:5751614|PMID:26681805)
MGI
Ensembl
PMID:24423645 PMID:26681805 GO_REF:0000107 MGI:5575728 MGI:5751614 NCBI chr 4:120,087,477...120,137,550
Ensembl chr 4:131,391,361...131,439,590
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MYO7A myosin VIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3769195|PMID:17712420) MGI
Ensembl
PMID:17712420 GO_REF:0000107 MGI:3769195 NCBI chr17:14,772,054...14,780,398
Ensembl chr17:14,996,420...15,004,242
JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25365221) MGI
Ensembl
PMID:25365221 GO_REF:0000107 NCBI chr 1:126,653,794...126,689,690
Ensembl chr 1:130,300,844...130,336,311
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3612221|PMID:16368712)
(MGI:3654230|PMID:16542649)
MGI
Ensembl
PMID:16368712 PMID:16542649 GO_REF:0000107 MGI:3612221 MGI:3654230 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609
JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4879078|PMID:20920792) MGI
Ensembl
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095
JBrowse link
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5749311|PMID:26284655)
(PMID:25365221)
(MGI:6141536|PMID:28237315), (MGI:6433162|PMID:31637311)
MGI
Ensembl
PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 GO_REF:0000107 MGI:5749311 MGI:6141536 MGI:6433162 NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616
JBrowse link
G TFEB transcription factor EB involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6433162|PMID:31637311) Ensembl
MGI
PMID:31637311 GO_REF:0000107 MGI:6433162 NCBI chr 6:41,268,169...41,320,822
Ensembl chr 6:42,574,416...42,627,031
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5588048|PMID:25066864) MGI
Ensembl
PMID:25066864 GO_REF:0000107 MGI:5588048 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693
JBrowse link
G TPCN2 two pore segment channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:64,139,512...64,227,913
Ensembl chr11:67,438,635...67,478,106
JBrowse link
G TPP1 tripeptidyl peptidase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3522013|PMID:15483130) MGI
Ensembl
PMID:15483130 GO_REF:0000107 MGI:3522013 NCBI chr11:6,744,815...6,751,556
Ensembl chr11:6,427,522...6,434,222
JBrowse link
G VPS18 VPS18 core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,836,707...19,846,231
Ensembl chr15:38,086,518...38,095,835
JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr16:26,924,901...26,954,443
Ensembl chr16:45,817,371...45,846,531
JBrowse link
G WASHC5 WASH complex subunit 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6199426|PMID:30061306) MGI
Ensembl
PMID:30061306 GO_REF:0000107 MGI:6199426 NCBI chr 8:121,710,118...121,777,977
Ensembl chr 8:124,461,424...124,529,262
JBrowse link
G ZFYVE26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25365221) MGI
Ensembl
PMID:25365221 GO_REF:0000107 NCBI chr14:48,326,517...48,396,486
Ensembl chr14:67,206,236...67,273,580
JBrowse link
G ZKSCAN3 zinc finger with KRAB and SCAN domains 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,157,736...28,174,906
Ensembl chr 6:28,828,298...28,847,596
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,026,525...33,052,252
Ensembl chr  X:40,730,677...40,756,209
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr2B:28,624,800...28,629,543 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:11722572) UniProt PMID:11722572
G CLN5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242
JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609
JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4879078|PMID:20920792) MGI
Ensembl
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6101836|PMID:28728022) MGI
Ensembl
PMID:28728022 GO_REF:0000107 MGI:6101836 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,412,229...28,416,840
Ensembl chr17:28,914,604...28,919,194
JBrowse link
G TMEM9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,734,640...176,771,476
Ensembl chr 1:181,037,050...181,056,841
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,811,728...2,192,018
Ensembl chr15:25,181,386...25,523,774
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,357,549...76,398,571
Ensembl chr 5:81,743,254...81,784,565
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF1 ADP ribosylation factor 1 ISO RGD PMID:9538255 RGD:9684948 NCBI chr 1:203,484,803...203,501,395
Ensembl chr 1:208,695,615...208,712,105
JBrowse link
G ATP10B ATPase phospholipid transporting 10B (putative) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:155,952,876...156,234,942
Ensembl chr 5:162,646,009...162,862,268
JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100970314 charged multivesicular body protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:86,559,695...86,619,615
Ensembl chr2A:88,106,242...88,165,104
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:25561470 RGD:11561937 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1A coronin 1A involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G MYO7A myosin VIIA acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2662763|PMID:12743369) MGI
Ensembl
PMID:12743369 GO_REF:0000107 MGI:2662763 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3699774|PMID:11544318) MGI PMID:11544318 MGI:3699774 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G SRPX sushi repeat containing protein X-linked acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3852261|PMID:19368996) MGI
Ensembl
PMID:19368996 GO_REF:0000107 MGI:3852261 NCBI chr  X:30,598,574...30,670,464
Ensembl chr  X:38,303,313...38,378,770
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,069,592...5,127,301
Ensembl chr 3:5,169,950...5,225,543
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) UniProt PMID:26450516 MGI:5698740
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:95,505,376...95,597,792
Ensembl chr2B:213,628,997...213,721,299
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840
JBrowse link
G RAB20 RAB20, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:91,660,142...91,698,215
Ensembl chr13:110,778,119...110,815,408
JBrowse link
G RAB34 RAB34, member RAS oncogene family involved_in ISO (PMID:21255211)
(MGI:5467668|PMID:23197834)
UniProt
ParkinsonsUK-UCL
PMID:21255211 PMID:23197834 MGI:5467668 NCBI chr17:28,057,077...28,061,234
Ensembl chr17:28,562,118...28,566,242
JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,814,825...102,851,700
Ensembl chr11:106,291,348...106,326,587
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISO (PMID:21255211) UniProt PMID:21255211 NCBI chr 3:125,784,604...125,873,051 JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3690533|PMID:16982801) UniProt PMID:16982801 MGI:3690533 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPG11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5749311|PMID:26284655) MGI
Ensembl
PMID:26284655 GO_REF:0000107 MGI:5749311 NCBI chr15:23,519,311...23,620,532
Ensembl chr15:41,688,081...41,788,616
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9038169 RGD:10059368 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773
JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385
JBrowse link
G MT3 metallothionein 3 involved_in ISO (MGI:4881636|PMID:20544854) UniProt PMID:20544854 MGI:4881636 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:23,159,321...23,178,192
Ensembl chr  X:30,716,617...30,717,522
JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,484,896...68,541,808
Ensembl chr 4:75,075,427...75,104,629
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:119,831,693...119,868,132
Ensembl chr12:123,201,663...123,236,019
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:94,414,275...94,491,483
Ensembl chr 8:96,600,799...96,677,927
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:94,414,275...94,491,483
Ensembl chr 8:96,600,799...96,677,927
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6101836|PMID:28728022) MGI
Ensembl
PMID:28728022 GO_REF:0000107 MGI:6101836 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693
JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5460923|PMID:23160154) MGI
Ensembl
PMID:23160154 GO_REF:0000107 MGI:5460923 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15423
    cellular process 14248
      cellular component organization or biogenesis 5706
        cellular component organization 5558
          organelle organization 3108
            vacuole organization 172
              lytic vacuole organization 75
                lysosome organization 75
                  lysosomal membrane organization + 7
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 15
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 18
                  regulation of lysosome organization + 5
paths to the root