Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:protein catabolic process in the vacuole
go back to main search page
Accession:GO:0007039 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
Synonyms:related_synonym: vacuolar protein breakdown;   vacuolar protein catabolic process;   vacuolar protein catabolism;   vacuolar protein degradation


show annotations for term's descendants           Sort by:
protein catabolic process in the vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GID4 GID complex subunit 4 homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:41,455,823...41,477,478
Ensembl chr 5:41,458,936...41,474,358 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23704209) Ensembl
MGI		 PMID:23704209 GO_REF:0000107 NCBI chr18:49,784,480...49,794,361
Ensembl chr18:49,784,490...49,794,317 		JBrowse link
lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP5Z1 adaptor related protein complex 5 subunit zeta 1 acts_upstream_of_or_within ISO (PMID:30930081) MGI PMID:30930081 NCBI chr 6:12,847,699...12,858,769
Ensembl chr 6:12,847,713...12,858,681 		JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr25:19,027,014...19,031,467
Ensembl chr25:19,027,342...19,030,887 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033 		JBrowse link
G DPP7 dipeptidyl peptidase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chr 9:48,554,062...48,557,752
Ensembl chr 9:48,554,077...48,557,746 		JBrowse link
G GRN granulin precursor acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:92,405,946...92,444,527
Ensembl chr  X:92,407,950...92,444,765 		JBrowse link
G MGAT3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of ISO (PMID:25592972), (PMID:26467158) MGI PMID:25592972 PMID:26467158 NCBI chr10:25,564,825...25,605,787
Ensembl chr10:25,568,053...25,570,413 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:12813057) MGI PMID:12813057 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848 		JBrowse link
G SLC17A9 solute carrier family 17 member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:7447186|PMID:24962569) UniProt
Ensembl		 PMID:24962569 GO_REF:0000107 MGI:7447186 NCBI chr24:46,752,464...46,765,915
Ensembl chr24:46,752,107...46,766,375 		JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (PMID:28728022) MGI PMID:28728022 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333 		JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,607,688...42,614,776
Ensembl chr 9:42,607,733...42,611,445 		JBrowse link
G TPP1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28728022) Ensembl
MGI		 PMID:28728022 GO_REF:0000107 NCBI chr21:29,921,764...29,926,974
Ensembl chr21:29,921,764...29,926,986 		JBrowse link
G VPS13A vacuolar protein sorting 13 homolog A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:81,191,125...81,426,337
Ensembl chr 1:81,192,349...81,426,322 		JBrowse link
negative regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LAPTM4B lysosomal protein transmembrane 4 beta involved_in ISO (PMID:25588945) UniProt PMID:25588945 NCBI chr13:41,134...127,399
Ensembl chr13:41,121...127,182 		JBrowse link
G MGAT3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISO (PMID:25592972), (PMID:26467158) MGI PMID:25592972 PMID:26467158 NCBI chr10:25,564,825...25,605,787
Ensembl chr10:25,568,053...25,570,413 		JBrowse link
G USP8 ubiquitin specific peptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:16,341,970...16,408,246
Ensembl chr30:16,342,009...16,408,012 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr15:8,428,073...8,454,601
Ensembl chr15:8,428,172...8,454,049 		JBrowse link
positive regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355 		JBrowse link
G LRP1 LDL receptor related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271 		JBrowse link
G LRP2 LDL receptor related protein 2 involved_in ISO (PMID:9228033) ARUK-UCL PMID:9228033 NCBI chr36:13,910,450...14,107,081
Ensembl chr36:13,911,865...14,107,546 		JBrowse link
G MARCHF2 membrane associated ring-CH-type finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,976,503...52,990,694
Ensembl chr20:52,980,002...52,990,470 		JBrowse link
positive regulation of protein catabolic process in the vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in ISO (PMID:25635054) BHF-UCL PMID:25635054 NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868 		JBrowse link
regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A2 ATPase cation transporting 13A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:81,196,355...81,215,736
Ensembl chr 2:81,196,463...81,215,689 		JBrowse link
G MFSD8 major facilitator superfamily domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29514215) Ensembl
MGI		 PMID:29514215 GO_REF:0000107 NCBI chr19:12,905,336...13,030,901
Ensembl chr19:12,982,394...13,020,083 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    metabolic process 10933
      primary metabolic process 9494
        protein metabolic process 4323
          protein catabolic process 1033
            protein catabolic process in the vacuole 25
              lysosomal protein catabolic process + 22
              negative regulation of protein catabolic process in the vacuole + 4
              positive regulation of protein catabolic process in the vacuole + 5
              regulation of protein catabolic process in the vacuole + 11
Path 2
Term Annotations click to browse term
  biological_process 17878
    metabolic process 10933
      organic substance metabolic process 10478
        macromolecule metabolic process 8843
          macromolecule catabolic process 1504
            protein catabolic process 1033
              protein catabolic process in the vacuole 25
                lysosomal protein catabolic process + 22
                negative regulation of protein catabolic process in the vacuole + 4
                positive regulation of protein catabolic process in the vacuole + 5
                regulation of protein catabolic process in the vacuole + 11
paths to the root