Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:protein catabolic process in the vacuole
go back to main search page
Accession:GO:0007039 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
Synonyms:related_synonym: vacuolar protein breakdown;   vacuolar protein catabolic process;   vacuolar protein catabolism;   vacuolar protein degradation


show annotations for term's descendants           Sort by:
 
protein catabolic process in the vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973 (MGI:5500861|PMID:23704209) RGD PMID:23704209 MGI:5500861 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:1346962|PMID:10527801), (MGI:3757820|PMID:17855597) RGD PMID:10527801 PMID:17855597 MGI:1346962 MGI:3757820 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Dpp7 dipeptidylpeptidase 7 acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
JBrowse link
G Grn granulin precursor acts_upstream_of_or_within ISO MGI:3762618 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO
ISS
(PMID:24880125)
GO_REF:0000024
RGD
UniProt
PMID:24880125 GO_REF:0000024 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (MGI:2671637|PMID:12813057) RGD PMID:12813057 MGI:2671637 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISS
ISO
GO_REF:0000024
(PMID:28296633)
UniProt
RGD
PMID:28296633 GO_REF:0000024 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108
JBrowse link
G Tpp1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:6101836|PMID:28728022)
Ensembl
RGD
PMID:28728022 GO_REF:0000107 MGI:6101836 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129
JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A involved_in ISO (PMID:30709847) RGD PMID:30709847 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555
JBrowse link
negative regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
ISS
(PMID:25588945)
GO_REF:0000024
RGD
UniProt
PMID:25588945 GO_REF:0000024 NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase acts_upstream_of_or_within ISS
ISO
GO_REF:0000024
MGI:1857830 (MGI:5751042|PMID:25592972), (MGI:5816436|PMID:26467158)
UniProt
RGD
PMID:25592972 PMID:26467158 GO_REF:0000024 MGI:5751042 MGI:5816436 NCBI chr 7:111,708,353...111,761,825
Ensembl chr 7:111,675,730...111,762,026
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:5694519 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link
positive regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
(MGI:5902678|PMID:22383525)
Ensembl
RGD
PMID:22383525 GO_REF:0000107 MGI:5902678 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:23152628) RGD PMID:23152628 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp2 LDL receptor related protein 2 involved_in ISO (PMID:9228033) RGD PMID:9228033 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
positive regulation of protein catabolic process in the vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISO
IEA
(PMID:25635054)
GO_REF:0000107
RGD
Ensembl
PMID:25635054 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
regulation of lysosomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO UniProtKB:Q9CTG6 (PMID:23499937), (PMID:24334770)
(MGI:5780535|PMID:24334770)
RGD PMID:23499937 PMID:24334770 MGI:5780535 NCBI chr 5:153,292,722...153,312,143
Ensembl chr 5:153,292,751...153,312,139
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (MGI:6155546|PMID:29514215) RGD PMID:29514215 MGI:6155546 NCBI chr 2:123,822,042...123,882,913
Ensembl chr 2:123,816,614...123,857,971
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      cellular metabolic process 10717
        cellular macromolecule metabolic process 8204
          cellular protein metabolic process 5229
            cellular protein catabolic process 839
              protein catabolic process in the vacuole 20
                lysosomal protein catabolic process + 18
                negative regulation of protein catabolic process in the vacuole + 3
                positive regulation of protein catabolic process in the vacuole + 4
                regulation of protein catabolic process in the vacuole + 9
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        macromolecule metabolic process 9793
          macromolecule catabolic process 1359
            protein catabolic process 1007
              cellular protein catabolic process 839
                protein catabolic process in the vacuole 20
                  lysosomal protein catabolic process + 18
                  negative regulation of protein catabolic process in the vacuole + 3
                  positive regulation of protein catabolic process in the vacuole + 4
                  regulation of protein catabolic process in the vacuole + 9
paths to the root