Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of microtubule depolymerization
go back to main search page
Accession:GO:0007026 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
Synonyms:exact_synonym: down regulation of microtubule depolymerization;   downregulation of microtubule depolymerization;   microtubule stabilization;   negative regulation of microtubule disassembly
 narrow_synonym: inhibition of microtubule depolymerization;   microtubule rescue;   negative regulation of microtubule catastrophe



show annotations for term's descendants           Sort by:
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway acts_upstream_of_or_within
involved_in
IMP
IBA
IEA
IDA
(PMID:17192415)
(PMID:11166179)
MGI
GO_Central
TreeGrafter
UniProt
PMID:11166179 PMID:17192415 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239
JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:1,446,230...1,473,244
Ensembl chr19:1,446,302...1,473,244
JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in IMP (PMID:11912491) UniProt PMID:11912491 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070
JBrowse link
G ATXN7 ataxin 7 involved_in IMP (PMID:22100762) CACAO PMID:22100762 NCBI chr 3:63,863,144...64,003,462
Ensembl chr 3:63,863,155...64,003,462
JBrowse link
G BMERB1 bMERB domain containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:25099998) Ensembl
MGI
GO_Central
PMID:25099998 GO_REF:0000033 GO_REF:0000107 NCBI chr16:15,434,588...15,588,259
Ensembl chr16:15,434,475...15,625,028
JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:135,808,487...135,907,546
Ensembl chr 9:135,808,487...135,907,546
JBrowse link
G CAMSAP2 calmodulin regulated spectrin associated protein family member 2 involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 1:200,738,893...200,860,704
Ensembl chr 1:200,738,893...200,860,704
JBrowse link
G CIB1 calcium and integrin binding 1 involved_in IDA (PMID:21215777) UniProt PMID:21215777 NCBI chr15:90,229,975...90,265,759
Ensembl chr15:90,229,975...90,234,047
JBrowse link
G CKAP2 cytoskeleton associated protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:16061649) Ensembl
MGI
GO_Central
TreeGrafter
PMID:16061649 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628
JBrowse link
G CLASP1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within
IGI
ISO
IMP
(PMID:15631994)
(PMID:11290329)
(PMID:16866869)
UniProt
MGI
PMID:11290329 PMID:15631994 PMID:16866869 NCBI chr 2:121,337,776...121,649,462
Ensembl chr 2:121,337,776...121,649,476
JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within
involved_in
ISO
NAS
(PMID:11290329)
(PMID:17113391)
RGD
MGI
UniProt
PMID:11290329 PMID:17113391 RGD:68300 NCBI chr 3:33,496,245...33,718,254
Ensembl chr 3:33,496,245...33,718,356
JBrowse link
G DIAPH3 diaphanous related formin 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18458159) Ensembl
MGI
PMID:18458159 GO_REF:0000107 NCBI chr13:59,665,583...60,163,928
Ensembl chr13:59,665,583...60,163,928
JBrowse link
G EML4 EMAP like 4 acts_upstream_of_or_within ISO (PMID:17196341) MGI PMID:17196341 NCBI chr 2:42,169,353...42,332,548
Ensembl chr 2:42,169,353...42,332,548
JBrowse link
G FGF13 fibroblast growth factor 13 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:138,614,727...139,205,023
Ensembl chr  X:138,614,727...139,222,777
JBrowse link
G GAS2L1 growth arrest specific 2 like 1 involved_in IMP (PMID:12584248) UniProt PMID:12584248 NCBI chr22:29,306,650...29,312,787
Ensembl chr22:29,306,618...29,312,787
JBrowse link
G GAS2L2 growth arrest specific 2 like 2 involved_in IMP (PMID:12584248) UniProt PMID:12584248 NCBI chr17:35,744,511...35,753,239
Ensembl chr17:35,744,511...35,753,239
JBrowse link
G HDAC6 histone deacetylase 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12486003) Ensembl
MGI
PMID:12486003 GO_REF:0000107 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982
JBrowse link
G HDGFL3 HDGF like 3 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:83,112,738...83,207,823
Ensembl chr15:83,112,738...83,207,823
JBrowse link
G KATNB1 katanin regulatory subunit B1 involved_in IMP (PMID:10751153) UniProt PMID:10751153 NCBI chr16:57,735,770...57,757,244
Ensembl chr16:57,735,739...57,757,244
JBrowse link
G MAP1A microtubule associated protein 1A ISO RGD PMID:11896150 RGD:71122 NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620
JBrowse link
G MAP1B microtubule associated protein 1B involved_in ISO
IEA
RGD
Ensembl
PMID:11896150 GO_REF:0000107 RGD:71122 NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565
JBrowse link
G MAP2 microtubule associated protein 2 involved_in ISO PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147
JBrowse link
G MAP6D1 MAP6 domain containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16837464) Ensembl
MGI
PMID:16837464 GO_REF:0000107 NCBI chr 3:183,815,922...183,825,577
Ensembl chr 3:183,815,922...183,825,594
JBrowse link
G MID1 midline 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15070402) Ensembl
MGI
PMID:15070402 GO_REF:0000107 NCBI chr  X:10,445,310...10,833,683
Ensembl chr  X:10,445,310...10,833,654
JBrowse link
G MID1IP1 MID1 interacting protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
(PMID:15070402) UniProt
MGI
Ensembl
PMID:15070402 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:38,801,459...38,806,532
Ensembl chr  X:38,801,440...38,806,537
JBrowse link
G NAV3 neuron navigator 3 involved_in IMP (PMID:25678558) UniProt PMID:25678558 NCBI chr12:77,571,862...78,213,010
Ensembl chr12:77,324,641...78,213,010
JBrowse link
G SPECC1L sperm antigen with calponin homology and coiled-coil domains 1 like acts_upstream_of_or_within ISO (PMID:21703590) MGI PMID:21703590 NCBI chr22:24,270,831...24,417,738
Ensembl chr22:24,270,817...24,417,739
JBrowse link
G SPEF1 sperm flagellar 1 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,777,504...3,781,448
Ensembl chr20:3,777,504...3,781,448
JBrowse link
G STMN2 stathmin 2 involved_in IDA (PMID:18452648) UniProt PMID:18452648 NCBI chr 8:79,611,117...79,666,158
Ensembl chr 8:79,611,117...79,666,158
JBrowse link
G TAOK1 TAO kinase 1 involved_in IMP (PMID:12639963) ARUK-UCL PMID:12639963 NCBI chr17:29,390,363...29,551,903
Ensembl chr17:29,390,363...29,551,903
JBrowse link
G TPX2 TPX2 microtubule nucleation factor involved_in IDA (PMID:26414402) CACAO PMID:26414402 NCBI chr20:31,739,290...31,801,800
Ensembl chr20:31,739,271...31,801,805
JBrowse link
G TRIM54 tripartite motif containing 54 involved_in
acts_upstream_of_or_within
NAS
ISO
IEA
(PMID:11243782)
(PMID:10953002)
UniProt
MGI
Ensembl
PMID:10953002 PMID:11243782 GO_REF:0000107 NCBI chr 2:27,282,429...27,307,435
Ensembl chr 2:27,282,429...27,307,439
JBrowse link
G TTBK2 tau tubulin kinase 2 involved_in IDA (PMID:26323690) ARUK-UCL PMID:26323690 NCBI chr15:42,738,730...42,921,000
Ensembl chr15:42,738,730...42,920,809
JBrowse link
G WDR47 WD repeat domain 47 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:29078390) Ensembl
MGI
PMID:29078390 GO_REF:0000107 NCBI chr 1:108,970,214...109,042,102
Ensembl chr 1:108,970,214...109,042,113
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      negative regulation of cellular process 6046
        negative regulation of cellular component organization 868
          negative regulation of supramolecular fiber organization 197
            negative regulation of microtubule depolymerization 34
              negative regulation of astral microtubule depolymerization 0
              negative regulation of axonemal microtubule depolymerization 0
Path 2
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      cellular component organization or biogenesis 7533
        cellular component organization 7308
          organelle organization 3966
            cytoskeleton organization 1659
              microtubule cytoskeleton organization 719
                microtubule polymerization or depolymerization 151
                  regulation of microtubule polymerization or depolymerization 104
                    negative regulation of microtubule polymerization or depolymerization 47
                      negative regulation of microtubule depolymerization 34
                        negative regulation of astral microtubule depolymerization 0
                        negative regulation of axonemal microtubule depolymerization 0
paths to the root