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ONTOLOGY REPORT - ANNOTATIONS


Term:microtubule depolymerization
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Accession:GO:0007019 term browser browse the term
Definition:The removal of tubulin heterodimers from one or both ends of a microtubule.
Synonyms:exact_synonym: microtubule disassembly;   microtubule shortening
 narrow_synonym: microtubule catastrophe;   microtubule depolymerization during nuclear congression



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microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of ISO (MGI:3656452|PMID:16525027) RGD PMID:16525027 MGI:3656452 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of
involved_in
ISO
IEA
(MGI:5578117|PMID:25099998)
GO_REF:0000107
RGD
Ensembl
PMID:25099998 GO_REF:0000107 MGI:5578117 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of ISO MGI:3693618 (MGI:3693027|PMID:17113391) RGD PMID:17113391 MGI:3693027 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650
JBrowse link
G Kif14 kinesin family member 14 NOT|involved_in ISO (MGI:5607363|PMID:24949858) RGD PMID:24949858 MGI:5607363 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
JBrowse link
G Kif18a kinesin family member 18A involved_in IBA
ISO
PMID:21873635
(PMID:17346968)
RGD PMID:17346968 PMID:21873635 RGD:13792537 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
JBrowse link
G Kif18b kinesin family member 18B involved_in ISO
IBA
(PMID:21820309)
PMID:21873635
RGD PMID:21820309 PMID:21873635 RGD:13792537 NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850
JBrowse link
G Kif24 kinesin family member 24 involved_in ISO
IBA
(PMID:21620453)
PMID:21873635
RGD PMID:21620453 PMID:21873635 RGD:13792537 NCBI chr 5:56,561,019...56,628,040
Ensembl chr 5:56,561,154...56,628,025
JBrowse link
G Kif2b kinesin family member 2B involved_in ISO
ISS
(PMID:19060894)
GO_REF:0000024
RGD
UniProt
PMID:19060894 GO_REF:0000024 NCBI chr10:76,394,160...76,396,379 JBrowse link
G Kif2c kinesin family member 2C involved_in IEA
ISO
GO_REF:0000107
(PMID:19060894), (PMID:21820309)
Ensembl
RGD
PMID:19060894 PMID:21820309 GO_REF:0000107 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Nckap5 NCK-associated protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:37,369,948...38,283,257
Ensembl chr13:37,370,792...38,283,268
JBrowse link
G Nckap5l NCK-associated protein 5-like involved_in IBA
ISO
PMID:21873635
(PMID:26485573)
RGD PMID:26485573 PMID:21873635 RGD:13792537 NCBI chr 7:130,553,683...130,591,886
Ensembl chr 7:130,555,368...130,591,857
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IDA RGD PMID:16982696 RGD:1642763 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Smn1 survival of motor neuron 1, telomeric acts_upstream_of_or_within ISO (MGI:4439458|PMID:20176735) RGD PMID:20176735 MGI:4439458 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060
JBrowse link
G Stmn1 stathmin 1 acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
(PMID:9880330)
(PMID:10675326)
PMID:21873635
RGD PMID:9880330 PMID:10675326 PMID:9788875 PMID:21873635 RGD:61528, RGD:13792537 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stmn2 stathmin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Stmn3 stathmin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:168,416,810...168,424,946
Ensembl chr 3:168,416,810...168,425,056
JBrowse link
G Stmn4 stathmin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253
JBrowse link
G Stmnd1 stathmin domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:18,393,312...18,420,655
Ensembl chr17:18,394,346...18,437,412
JBrowse link
axonemal microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (MGI:5460922|PMID:23168168) RGD PMID:23168168 MGI:5460922 NCBI chr10:99,800,185...99,826,546
Ensembl chr10:99,799,400...99,826,546
JBrowse link
mitotic spindle microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccsap centriole, cilia and spindle-associated protein involved_in ISO (PMID:26562023) RGD PMID:26562023 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
JBrowse link
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
IBA
GO_REF:0000002
(PMID:17192415)
(PMID:11166179)
(MGI:3656452|PMID:16525027)
GO_REF:0000024
GO_REF:0000107
PMID:21873635
InterPro
RGD
UniProt
Ensembl
PMID:11166179 PMID:16525027 PMID:17192415 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:3656452, RGD:13792537 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO
ISS
IEA
(PMID:11912491)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:11912491 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Atxn7 ataxin 7 involved_in ISO (PMID:22100762) RGD PMID:22100762 NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106
JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:5578117|PMID:25099998)
PMID:21873635
RGD PMID:25099998 PMID:21873635 MGI:5578117, RGD:13792537 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575
JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:8,746,176...8,806,072
Ensembl chr 3:8,746,176...8,806,072
JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:47,723,121...47,802,597
Ensembl chr13:47,723,121...47,802,597
JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO
ISS
(PMID:21215777)
GO_REF:0000024
RGD
UniProt
PMID:21215777 GO_REF:0000024 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Ckap2 cytoskeleton associated protein 2 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3589528|PMID:16061649)
PMID:21873635
RGD PMID:16061649 PMID:21873635 MGI:3589528, RGD:13792537 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within
ISO UniProtKB:O75122 (PMID:15631994), (PMID:16866869)
(MGI:2176392|PMID:11290329)
RGD PMID:11290329 PMID:15631994 PMID:16866869 MGI:2176392 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within IDA
ISO
MGI:3693618 (MGI:2176392|PMID:11290329), (MGI:3693027|PMID:17113391) RGD PMID:11290329 PMID:17113391 PMID:11290329 MGI:2176392 MGI:3693027, RGD:68300 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 involved_in NAS PMID:11290329 UniProt PMID:11290329 RGD:68300 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (MGI:3709709|PMID:17196341) RGD PMID:17196341 MGI:3709709 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISS
ISO
GO_REF:0000024
(MGI:5431268|PMID:22726441)
UniProt
RGD
PMID:22726441 GO_REF:0000024 MGI:5431268 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 involved_in ISO
ISS
(PMID:12584248) RGD PMID:12584248 PMID:12584248 RGD:12790645 NCBI chr14:79,951,702...79,961,830
Ensembl chr14:79,950,555...79,961,438
JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12584248)
UniProt
RGD
PMID:12584248 GO_REF:0000024 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881
JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2447264|PMID:12486003)
GO_REF:0000107
RGD
Ensembl
PMID:12486003 GO_REF:0000107 MGI:2447264 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3849122|PMID:19237540)
UniProt
RGD
PMID:19237540 GO_REF:0000024 MGI:3849122 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650
JBrowse link
G Map1a microtubule-associated protein 1A IDA RGD PMID:11896150 RGD:71122 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map1b microtubule-associated protein 1B IDA RGD PMID:11896150 RGD:71122 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2 microtubule-associated protein 2 involved_in IMP PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map6d1 MAP6 domain containing 1 acts_upstream_of_or_within ISO (MGI:3695226|PMID:16837464) RGD PMID:16837464 MGI:3695226 NCBI chr11:80,734,148...80,740,377
Ensembl chr11:80,734,148...80,740,377
JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within ISO MGI:1915291 (MGI:3046496|PMID:15070402) RGD PMID:15070402 MGI:3046496 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353
JBrowse link
G Mid1ip1 MID1 interacting protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1100537 (MGI:3046496|PMID:15070402)
UniProt
RGD
PMID:15070402 GO_REF:0000024 MGI:3046496 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774
JBrowse link
G Nav3 neuron navigator 3 involved_in ISO (PMID:25678558) RGD PMID:25678558 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO (MGI:5433266|PMID:21703590) RGD PMID:21703590 MGI:5433266 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665
JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (MGI:5908342|PMID:16206169) RGD PMID:16206169 MGI:5908342 NCBI chr 3:118,390,659...118,396,842
Ensembl chr 3:118,390,575...118,394,531
JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) RGD PMID:18452648 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
IEA
(PMID:12639963)
GO_REF:0000107
RGD
Ensembl
PMID:12639963 GO_REF:0000107 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO (PMID:26414402) RGD PMID:26414402 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Trim54 tripartite motif-containing 54 acts_upstream_of_or_within ISO (MGI:1888564|PMID:10953002) RGD PMID:10953002 MGI:1888564 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) RGD PMID:26323690 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
JBrowse link
plus-end specific microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (MGI:5460922|PMID:23168168) RGD PMID:23168168 MGI:5460922 NCBI chr10:99,800,185...99,826,546
Ensembl chr10:99,799,400...99,826,546
JBrowse link
positive regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A IDA RGD PMID:18442977 RGD:7241017 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650
JBrowse link
G Spast spastin involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) RGD PMID:18452648 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in IDA PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map1a microtubule-associated protein 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map1b microtubule-associated protein 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map1s microtubule-associated protein 1S involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          supramolecular fiber organization 821
            microtubule depolymerization 54
              astral microtubule depolymerization + 0
              cytoplasmic microtubule depolymerization + 1
              minus-end specific microtubule depolymerization 0
              mitotic spindle microtubule depolymerization 1
              negative regulation of microtubule depolymerization + 34
              plus-end specific microtubule depolymerization 1
              positive regulation of microtubule depolymerization 5
              regulation of microtubule depolymerization + 38
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          organelle organization 3900
            cytoskeleton organization 1494
              microtubule cytoskeleton organization 647
                microtubule polymerization or depolymerization 133
                  microtubule depolymerization 54
                    astral microtubule depolymerization + 0
                    cytoplasmic microtubule depolymerization + 1
                    minus-end specific microtubule depolymerization 0
                    mitotic spindle microtubule depolymerization 1
                    negative regulation of microtubule depolymerization + 34
                    plus-end specific microtubule depolymerization 1
                    positive regulation of microtubule depolymerization 5
                    regulation of microtubule depolymerization + 38
paths to the root