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ONTOLOGY REPORT - ANNOTATIONS


Term:microtubule depolymerization
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Accession:GO:0007019 term browser browse the term
Definition:The removal of tubulin heterodimers from one or both ends of a microtubule.
Synonyms:exact_synonym: microtubule disassembly;   microtubule shortening
 narrow_synonym: microtubule catastrophe;   microtubule depolymerization during nuclear congression


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microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Katnb1 katanin regulatory subunit B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:10,340,027...10,360,319
Ensembl chr19:10,340,307...10,360,310
JBrowse link
G Kif14 kinesin family member 14 NOT|involved_in ISO (MGI:5607363|PMID:24949858) RGD PMID:24949858 MGI:5607363 NCBI chr13:53,350,073...53,421,992
Ensembl chr13:53,351,717...53,420,111
JBrowse link
G Kif18a kinesin family member 18A involved_in IBA
ISO
PMID:21873635
(PMID:17346968)
RGD PMID:17346968, PMID:21873635 RGD:13792537 NCBI chr 3:100,366,168...100,426,867
Ensembl chr 3:100,366,168...100,427,030
JBrowse link
G Kif18b kinesin family member 18B involved_in ISO
IBA
(PMID:21820309)
PMID:21873635
RGD PMID:21820309, PMID:21873635 RGD:13792537 NCBI chr10:91,008,294...91,027,760
Ensembl chr10:91,008,269...91,027,738
JBrowse link
G Kif24 kinesin family member 24 involved_in ISO (PMID:21620453) RGD PMID:21620453 NCBI chr 5:57,778,730...57,845,642
Ensembl chr 5:57,780,389...57,845,509
JBrowse link
G Kif2b kinesin family member 2B involved_in ISO
ISS
(PMID:19060894)
GO_REF:0000024
RGD
UniProt
PMID:19060894 GO_REF:0000024 NCBI chr10:79,095,588...79,097,807
Ensembl chr10:79,095,593...79,097,807
JBrowse link
G Kif2c kinesin family member 2C involved_in IEA
ISO
GO_REF:0000107
(PMID:19060894), (PMID:21820309)
Ensembl
RGD
PMID:19060894 PMID:21820309 GO_REF:0000107 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Nckap5 NCK-associated protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:42,265,875...43,049,232
Ensembl chr13:42,265,806...42,885,440
JBrowse link
G Nckap5l NCK-associated protein 5-like involved_in IBA
ISO
PMID:21873635
(PMID:26485573)
RGD PMID:26485573, PMID:21873635 RGD:13792537 NCBI chr 7:141,081,943...141,093,924
Ensembl chr 7:141,081,943...141,095,691
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IDA RGD PMID:16982696 RGD:1642763 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Smn1 survival of motor neuron 1, telomeric involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4439458|PMID:20176735)
Ensembl
RGD
PMID:20176735 GO_REF:0000107 MGI:4439458 NCBI chr 2:30,360,101...30,371,147
Ensembl chr 2:30,360,100...30,371,147
JBrowse link
G Stmn1 stathmin 1 acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
(PMID:9880330)
(PMID:10675326)
PMID:21873635
RGD PMID:9880330 PMID:10675326, PMID:9788875, PMID:21873635 RGD:61528, RGD:13792537 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Stmn2 stathmin 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:95,424,251...95,471,900
Ensembl chr 2:95,424,251...95,472,115
JBrowse link
G Stmn3 stathmin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:176,808,016...176,816,108
Ensembl chr 3:176,808,017...176,816,162
JBrowse link
G Stmn4 stathmin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:43,007,901...43,025,852
Ensembl chr15:43,007,908...43,025,852
JBrowse link
G Stmnd1 stathmin domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:18,801,170...18,829,170
Ensembl chr17:18,802,399...18,828,929
Ensembl chr17:18,802,399...18,828,929
JBrowse link
axonemal microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (MGI:5460922|PMID:23168168) RGD PMID:23168168 MGI:5460922 NCBI chr10:103,308,392...103,334,466
Ensembl chr10:103,308,392...103,334,466
JBrowse link
mitotic spindle microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccsap centriole, cilia and spindle-associated protein involved_in ISO (PMID:26562023) RGD PMID:26562023 NCBI chr19:56,615,326...56,634,031
Ensembl chr19:56,617,399...56,633,633
JBrowse link
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
IBA
GO_REF:0000002
(PMID:17192415)
(PMID:11166179)
(MGI:3656452|PMID:16525027)
GO_REF:0000024
GO_REF:0000107
PMID:21873635
InterPro
RGD
UniProt
Ensembl
PMID:11166179 PMID:16525027 PMID:17192415, PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:3656452, RGD:13792537 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:11912491)
UniProt
RGD
PMID:11912491 GO_REF:0000024 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Atxn7 ataxin 7 involved_in ISO (PMID:22100762) RGD PMID:22100762 NCBI chr15:12,421,432...12,569,649
Ensembl chr15:12,425,175...12,513,931
JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of_or_within ISO (MGI:5578117|PMID:25099998) RGD PMID:25099998 MGI:5578117 NCBI chr10:3,411,380...3,570,689
Ensembl chr10:3,411,380...3,570,688
JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:3,373,971...3,434,027
Ensembl chr 3:3,373,971...3,434,027
JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:53,145,712...53,225,349
Ensembl chr13:53,145,712...53,225,349
JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:2,133,935...2,157,403
Ensembl chr12:2,134,022...2,157,403
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO
ISS
(PMID:21215777)
GO_REF:0000024
RGD
UniProt
PMID:21215777 GO_REF:0000024 NCBI chr 1:142,014,962...142,020,461
Ensembl chr 1:142,014,958...142,020,525
JBrowse link
G Ckap2 cytoskeleton associated protein 2 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3589528|PMID:16061649)
PMID:21873635
RGD PMID:16061649, PMID:21873635 MGI:3589528, RGD:13792537 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within
ISO UniProtKB:O75122 (PMID:15631994), (PMID:16866869)
(MGI:2176392|PMID:11290329)
RGD PMID:11290329 PMID:15631994 PMID:16866869 MGI:2176392 NCBI chr13:34,365,038...34,584,651
Ensembl chr13:34,365,147...34,584,651
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within IDA
ISO
MGI:3693618 (MGI:2176392|PMID:11290329), (MGI:3693027|PMID:17113391) RGD PMID:11290329 PMID:17113391, PMID:11290329 MGI:2176392 MGI:3693027, RGD:68300 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 involved_in NAS PMID:11290329 UniProt PMID:11290329 RGD:68300 NCBI chr12:25,172,957...25,236,935
Ensembl chr12:25,173,005...25,237,009
JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (MGI:3709709|PMID:17196341) RGD PMID:17196341 MGI:3709709 NCBI chr 6:6,618,370...6,674,550
Ensembl chr 6:6,619,076...6,674,554
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISS
ISO
GO_REF:0000024
(MGI:5431268|PMID:22726441)
UniProt
RGD
PMID:22726441 GO_REF:0000024 MGI:5431268 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 involved_in ISO
ISS
(PMID:12584248) RGD PMID:12584248, PMID:12584248 RGD:12790645 NCBI chr14:85,308,443...85,318,475
Ensembl chr14:85,308,443...85,318,194
JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12584248)
UniProt
RGD
PMID:12584248 GO_REF:0000024 NCBI chr10:70,639,429...70,646,402
Ensembl chr10:70,639,862...70,646,495
JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO (MGI:2447264|PMID:12486003) RGD PMID:12486003 MGI:2447264 NCBI chr  X:15,396,185...15,417,486
Ensembl chr  X:15,295,473...15,316,671
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3849122|PMID:19237540)
UniProt
RGD
PMID:19237540 GO_REF:0000024 MGI:3849122 NCBI chr 1:143,702,864...143,752,060
Ensembl chr 1:143,702,853...143,751,789
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:10,340,027...10,360,319
Ensembl chr19:10,340,307...10,360,310
JBrowse link
G Map1a microtubule-associated protein 1A IDA RGD PMID:11896150 RGD:71122 NCBI chr 3:113,251,918...113,272,193
Ensembl chr 3:113,251,778...113,272,186
JBrowse link
G Map1b microtubule-associated protein 1B IDA RGD PMID:11896150 RGD:71122 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map2 microtubule-associated protein 2 involved_in IMP PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map6d1 MAP6 domain containing 1 acts_upstream_of_or_within ISO (MGI:3695226|PMID:16837464) RGD PMID:16837464 MGI:3695226 NCBI chr11:84,321,078...84,327,307
Ensembl chr11:84,321,078...84,327,307
JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within ISO MGI:1915291 (MGI:3046496|PMID:15070402) RGD PMID:15070402 MGI:3046496 NCBI chr  X:25,458,782...25,839,941
Ensembl chr  X:25,458,771...25,628,272
JBrowse link
G Mid1ip1 MID1 interacting protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1100537 (MGI:3046496|PMID:15070402)
UniProt
RGD
PMID:15070402 GO_REF:0000024 MGI:3046496 NCBI chr  X:13,114,557...13,119,274
Ensembl chr  X:13,114,569...13,116,743
JBrowse link
G Nav3 neuron navigator 3 involved_in ISO (PMID:25678558) RGD PMID:25678558 NCBI chr 7:52,164,805...52,508,145
Ensembl chr 7:52,165,233...52,404,774
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO (MGI:5433266|PMID:21703590) RGD PMID:21703590 MGI:5433266 NCBI chr20:14,287,470...14,393,879
Ensembl chr20:14,287,457...14,393,793
JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (MGI:5908342|PMID:16206169) RGD PMID:16206169 MGI:5908342 NCBI chr 3:123,712,907...123,720,787
Ensembl chr 3:123,714,564...123,718,432
JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) RGD PMID:18452648 NCBI chr 2:95,424,251...95,471,900
Ensembl chr 2:95,424,251...95,472,115
JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
IEA
(PMID:12639963)
GO_REF:0000107
RGD
Ensembl
PMID:12639963 GO_REF:0000107 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO (PMID:26414402) RGD PMID:26414402 NCBI chr 3:148,327,965...148,370,187
Ensembl chr 3:148,327,965...148,370,187
JBrowse link
G Trim54 tripartite motif-containing 54 acts_upstream_of_or_within ISO (MGI:1888564|PMID:10953002) RGD PMID:10953002 MGI:1888564 NCBI chr 6:26,603,364...26,623,950
Ensembl chr 6:26,603,369...26,624,092
JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) RGD PMID:26323690 NCBI chr 3:112,677,932...112,789,615
Ensembl chr 3:112,684,152...112,789,289
JBrowse link
plus-end specific microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (MGI:5460922|PMID:23168168) RGD PMID:23168168 MGI:5460922 NCBI chr10:103,308,392...103,334,466
Ensembl chr10:103,308,392...103,334,466
JBrowse link
positive regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A IDA RGD PMID:18442977 RGD:7241017 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:10,340,027...10,360,319
Ensembl chr19:10,340,307...10,360,310
JBrowse link
G Spast spastin involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:22,230,067...22,282,166
Ensembl chr 6:22,230,928...22,281,886
JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) RGD PMID:18452648 NCBI chr 2:95,424,251...95,471,900
Ensembl chr 2:95,424,251...95,472,115
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in IDA PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map1a microtubule-associated protein 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:113,251,918...113,272,193
Ensembl chr 3:113,251,778...113,272,186
JBrowse link
G Map1b microtubule-associated protein 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map1s microtubule-associated protein 1S involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:20,268,663...20,278,850
Ensembl chr16:20,267,581...20,278,814
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      microtubule-based process 938
        microtubule cytoskeleton organization 639
          microtubule polymerization or depolymerization 133
            microtubule depolymerization 54
              astral microtubule depolymerization + 0
              cytoplasmic microtubule depolymerization + 1
              minus-end specific microtubule depolymerization 0
              mitotic spindle microtubule depolymerization 1
              negative regulation of microtubule depolymerization + 34
              plus-end specific microtubule depolymerization 1
              positive regulation of microtubule depolymerization 5
              regulation of microtubule depolymerization + 38
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cellular component organization or biogenesis 6721
        cellular component organization 6481
          organelle organization 4060
            cytoskeleton organization 1453
              microtubule cytoskeleton organization 639
                microtubule polymerization or depolymerization 133
                  microtubule depolymerization 54
                    astral microtubule depolymerization + 0
                    cytoplasmic microtubule depolymerization + 1
                    minus-end specific microtubule depolymerization 0
                    mitotic spindle microtubule depolymerization 1
                    negative regulation of microtubule depolymerization + 34
                    plus-end specific microtubule depolymerization 1
                    positive regulation of microtubule depolymerization 5
                    regulation of microtubule depolymerization + 38
paths to the root