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ONTOLOGY REPORT - ANNOTATIONS

Term:telomere maintenance via telomerase
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Accession:GO:0007004 term browser browse the term
Definition:The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
Synonyms:exact_synonym: telomerase-dependent telomere maintenance


show annotations for term's descendants           Sort by:
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:870,405...876,937
Ensembl chr10:870,392...909,161 		JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884 		JBrowse link
G GAR1 GAR1 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chr32:29,995,710...30,004,545
Ensembl chr32:29,996,148...30,004,536 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G LOC100687242 heat shock protein HSP 90-beta-like involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,591,965...7,594,265 JBrowse link
G NHP2 NHP2 ribonucleoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:3,389,549...3,393,010
Ensembl chr11:3,389,591...3,395,313 		JBrowse link
G NOP10 NOP10 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chr30:766,801...767,615
Ensembl chr30:766,853...767,613 		JBrowse link
G PARP4 poly(ADP-ribose) polymerase family member 4 NOT|acts_upstream_of_or_within ISO (PMID:15169895) MGI PMID:15169895 NCBI chr25:18,447,413...18,544,990
Ensembl chr25:18,447,413...18,544,777 		JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 acts_upstream_of_or_within ISO (PMID:11701125) MGI PMID:11701125 NCBI chr25:27,090,244...27,182,377
Ensembl chr25:27,021,704...27,181,968 		JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956 		JBrowse link
G PTGES3 prostaglandin E synthase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:885,744...903,814
Ensembl chr10:870,392...909,161 		JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819 		JBrowse link
G RPA1 replication protein A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:45,958,566...46,034,850
Ensembl chr 9:45,958,619...46,034,328 		JBrowse link
G TELO2 telomere maintenance 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:39,309,224...39,320,215
Ensembl chr 6:39,310,466...39,359,491 		JBrowse link
G TEP1 telomerase associated protein 1 NOT|acts_upstream_of_or_within ISO (PMID:15169895) MGI PMID:15169895 NCBI chr15:17,716,887...17,748,485
Ensembl chr15:17,716,887...17,764,356 		JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:21,664,378...21,701,491
Ensembl chr29:21,664,186...21,700,495 		JBrowse link
G TERT telomerase reverse transcriptase involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,574,153...32,586,222
Ensembl chr 5:32,574,134...32,594,333 		JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639 		JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,033,474...33,055,004
Ensembl chr 5:33,033,596...33,055,142 		JBrowse link
G DCP2 decapping mRNA 2 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 4:35,256,772...35,298,974
Ensembl chr 4:35,256,970...35,299,021 		JBrowse link
G EXOSC10 exosome component 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,942,801...84,964,129
Ensembl chr 2:84,942,777...84,964,130 		JBrowse link
G GNL3L G protein nucleolar 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:46,270,162...46,296,972
Ensembl chr  X:46,189,870...46,296,966 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:35,832,956...35,842,898
Ensembl chr 7:35,833,988...35,843,754 		JBrowse link
G LOC475399 heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr15:18,239,810...18,299,065 JBrowse link
G NAT10 N-acetyltransferase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:33,654,701...33,692,642
Ensembl chr18:33,655,311...33,689,923 		JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr30:29,223,507...29,232,584
Ensembl chr30:29,157,119...29,232,043 		JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:21119197)
(PMID:11701125)		 BHF-UCL PMID:11701125 PMID:21119197 NCBI chr25:27,090,244...27,182,377
Ensembl chr25:27,021,704...27,181,968 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G STN1 STN1 subunit of CST complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:16,203,607...16,246,468
Ensembl chr28:16,204,073...16,246,058 		JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:4,635,192...4,658,455
Ensembl chr 9:4,635,354...4,658,252 		JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 2:65,068,088...65,147,853
Ensembl chr 2:65,071,111...65,147,896 		JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:21,664,378...21,701,491
Ensembl chr29:21,664,186...21,700,495 		JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342 		JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,221,183...4,223,863
Ensembl chr 8:4,221,269...4,223,512 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TSR2 TSR2 ribosome maturation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:46,189,810...46,194,949
Ensembl chr  X:46,189,870...46,296,966 		JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639 		JBrowse link
G ATM ATM serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207 		JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr23:38,131,956...38,223,888
Ensembl chr23:38,132,788...38,224,016 		JBrowse link
G AURKB aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 5:33,014,098...33,028,951
Ensembl chr 5:33,014,102...33,033,948 		JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr10:11,560,287...11,586,559
Ensembl chr10:11,560,396...11,578,433 		JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,566,274...41,583,903
Ensembl chr 7:41,566,292...41,584,863 		JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:61,859,148...61,874,030
Ensembl chr10:61,859,245...61,874,389 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:4,035,851...4,049,131
Ensembl chr34:4,035,857...4,049,244 		JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:546,278...556,996
Ensembl chr 6:546,307...557,001 		JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:24,061,185...24,075,002
Ensembl chr31:24,061,252...24,075,364 		JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5428344|PMID:22723415) BHF-UCL
Ensembl		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15240872) Ensembl
MGI		 PMID:15240872 GO_REF:0000107 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884 		JBrowse link
G FBXO4 F-box protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:67,620,947...67,664,862
Ensembl chr 4:67,651,275...67,664,915 		JBrowse link
G GCH1 GTP cyclohydrolase 1 ISO RGD PMID:30690003 RGD:401717569 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156 		JBrowse link
G HMBOX1 homeobox containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,489,472...28,679,322
Ensembl chr25:28,489,506...28,679,748 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891 		JBrowse link
G LOC100856782 T-complex protein 1 subunit eta involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr34:37,026,053...37,027,839 JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150 		JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,590,615...49,702,289
Ensembl chr 1:49,548,274...49,702,289 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,317,061...37,322,792
Ensembl chr13:37,316,424...37,322,792 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,380,551...9,420,564
Ensembl chr26:9,319,180...9,419,236 		JBrowse link
G NEK2 NIMA related kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:10,039,617...10,052,511
Ensembl chr 7:10,040,187...10,052,512 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:4,557,754...4,755,912
Ensembl chr 7:4,555,231...4,704,955 		JBrowse link
G PARN poly(A)-specific ribonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,629,137...28,783,671
Ensembl chr 6:28,629,174...28,783,901 		JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:61,960,466...62,049,553
Ensembl chr 1:61,967,129...62,088,547 		JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,695,649...106,707,229
Ensembl chr 1:106,694,589...106,702,150 		JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956 		JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337 		JBrowse link
G TCP1 t-complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,029,260...49,038,023
Ensembl chr 1:49,029,282...49,038,020 		JBrowse link
G TNKS tankyrase involved_in ISO (PMID:11739745)
(PMID:12782650), (PMID:18221737)		 BHF-UCL PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:34,826,248...35,040,004
Ensembl chr16:34,831,662...35,039,946 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:23,095,769...23,185,680
Ensembl chr37:23,095,754...23,185,586 		JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207 		JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956 		JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    metabolic process 10933
      organic substance metabolic process 10478
        organic substance biosynthetic process 7730
          macromolecule biosynthetic process 6850
            DNA biosynthetic process 171
              RNA-templated DNA biosynthetic process 67
                telomere maintenance via telomerase 67
                  negative regulation of telomere maintenance via telomerase 22
                  positive regulation of telomere maintenance via telomerase 33
                  regulation of telomere maintenance via telomerase + 52
Path 2
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular metabolic process 9610
        cellular aromatic compound metabolic process 5577
          nucleobase-containing compound metabolic process 5349
            nucleic acid metabolic process 4781
              DNA metabolic process 942
                DNA biosynthetic process 171
                  RNA-templated DNA biosynthetic process 67
                    telomere maintenance via telomerase 67
                      negative regulation of telomere maintenance via telomerase 22
                      positive regulation of telomere maintenance via telomerase 33
                      regulation of telomere maintenance via telomerase + 52
paths to the root