ONTOLOGY REPORT - ANNOTATIONS
Term: response to sterol depletion
Accession: GO:0006991
browse the term
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms: exact_synonym: sterol depletion response
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Insig1
insulin induced gene 1
acts_upstream_of_or_within
ISO
(MGI:2388133|PMID:12242332)
RGD
PMID:12242332
MGI:2388133
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Insig2
insulin induced gene 2
acts_upstream_of_or_within
ISO
(MGI:2388215|PMID:12354157)
RGD
PMID:12354157
MGI:2388215
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
IEP
RGD
PMID:10330413
RGD:2303706
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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Pip4p1
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:25035345), (PMID:29146937)
UniProt RGD
PMID:25035345 PMID:29146937
GO_REF:0000024
NCBI chr15:24,146,854...24,150,739
Ensembl chr15:24,146,856...24,150,702
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Npc1l1
NPC1 like intracellular cholesterol transporter 1
involved_in
ISO
(PMID:19325169)
RGD
PMID:19325169
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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Mir96
microRNA 96
involved_in
ISO
(PMID:30460077)
RGD
PMID:30460077
NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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Spring1
SREBF pathway regulator in golgi 1
involved_in
ISO
(PMID:32111832) (MGI:6401656|PMID:32111832)
RGD
PMID:32111832
MGI:6401656
NCBI chr12:38,306,227...38,329,175
Ensembl chr12:38,297,837...38,329,138
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Zbtb7b
zinc finger and BTB domain containing 7B
involved_in
ISO
(MGI:6120228|PMID:29420538)
RGD
PMID:29420538
MGI:6120228
NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
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Amfr
autocrine motility factor receptor
involved_in
ISO
(MGI:6276494|PMID:22863805)
RGD
PMID:22863805
MGI:6276494
NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247
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Tmed2
transmembrane p24 trafficking protein 2
acts_upstream_of_or_within involved_in
ISO IEA
MGI:4456438 (MGI:5914333|PMID:28797121) GO_REF:0000107
RGD Ensembl
PMID:28797121
GO_REF:0000107 MGI:5914333
NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
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Arhgef10l
Rho guanine nucleotide exchange factor 10 like
involved_in
ISO IBA
(PMID:16112081) PMID:21873635
RGD
PMID:16112081 PMID:21873635
RGD:13792537
NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538
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Eif2a
eukaryotic translation initiation factor 2A
acts_upstream_of_or_within
ISO
(MGI:3815371|PMID:18852460)
RGD
PMID:18852460
MGI:3815371
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
acts_upstream_of_or_within
ISO
(MGI:3815371|PMID:18852460)
RGD
PMID:18852460
MGI:3815371
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Erlin1
ER lipid raft associated 1
involved_in
ISO IBA
(PMID:24217618) PMID:21873635
RGD
PMID:24217618 PMID:21873635
RGD:13792537
NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
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Erlin2
ER lipid raft associated 2
involved_in
IBA ISO
PMID:21873635 (PMID:24217618)
RGD
PMID:24217618 PMID:21873635
RGD:13792537
NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
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Insig1
insulin induced gene 1
involved_in
ISO IBA
(PMID:12242332), (PMID:32322062) PMID:21873635
RGD
PMID:12242332 PMID:32322062 PMID:21873635
RGD:13792537
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Insig2
insulin induced gene 2
involved_in
ISS IEA IBA ISO
GO_REF:0000024 GO_REF:0000107 PMID:21873635 (PMID:12242332), (PMID:17428920), (PMID:32322062)
UniProt Ensembl RGD
PMID:12242332 PMID:17428920 PMID:32322062 PMID:21873635
GO_REF:0000024 GO_REF:0000107, RGD:13792537
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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LOC120102490
insulin-induced gene 1 protein-like
involved_in
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:67,330,588...67,331,346
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Scap
SREBF chaperone
involved_in
ISO ISS
(PMID:11726962), (PMID:32322062) GO_REF:0000024
RGD UniProt
PMID:11726962 PMID:32322062
GO_REF:0000024
NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
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Srebf1
sterol regulatory element binding transcription factor 1
involved_in
ISO ISS
(PMID:27614840) GO_REF:0000024 (PMID:32322062)
RGD UniProt
PMID:27614840 PMID:32322062
GO_REF:0000024
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srebf2
sterol regulatory element binding transcription factor 2
involved_in
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 (PMID:32322062) (PMID:27614840)
Ensembl UniProt RGD
PMID:27614840 PMID:32322062
GO_REF:0000024 GO_REF:0000107
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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Insig1
insulin induced gene 1
involved_in
IBA ISO
PMID:21873635 (PMID:12202038), (PMID:15899885), (PMID:32322062)
RGD
PMID:12202038 PMID:15899885 PMID:32322062 PMID:21873635
RGD:13792537
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Insig2
insulin induced gene 2
involved_in
IBA IEA ISO ISS
PMID:21873635 GO_REF:0000107 (PMID:15899885), (PMID:32322062) GO_REF:0000024
Ensembl RGD UniProt
PMID:15899885 PMID:32322062 PMID:21873635
GO_REF:0000024 GO_REF:0000107, RGD:13792537
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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LOC120102490
insulin-induced gene 1 protein-like
involved_in
IBA
PMID:21873635
GO_Central
PMID:21873635
RGD:13792537
NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:67,330,588...67,331,346
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