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ONTOLOGY REPORT - ANNOTATIONS


Term:complement activation
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Accession:GO:0006956 term browser browse the term
Definition:Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
Synonyms:exact_synonym: complement cascade;   complement response
 related_synonym: complement activity



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complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain involved_in TAS (PMID:9461517) PINC PMID:9461517 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,636,628...22,639,678
JBrowse link
G C1QB complement C1q B chain involved_in TAS (PMID:1706597) PINC PMID:1706597 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
JBrowse link
G C2 complement C2 involved_in IMP
IDA
(PMID:19302245)
(PMID:12878586), (PMID:6906228)
BHF-UCL
ComplexPortal
PMID:6906228 PMID:12878586 PMID:19302245 NCBI chr 6:31,897,783...31,945,672
Ensembl chr 6:31,897,785...31,945,672
JBrowse link
G C3 complement C3 involved_in
acts_upstream_of_or_within
IBA
IDA
ISO
IMP
IEA
(PMID:21873635)
(PMID:12878586), (PMID:6225800)
(MGI:3833206|PMID:18947875)
(MGI:5617896|PMID:25284781)
(PMID:19302245)
GO_Central
ComplexPortal
MGI
RGD
BHF-UCL
InterPro
PMID:6225800 PMID:12878586 PMID:18947875 PMID:19302245 PMID:20712003 More... GO_REF:0000002 MGI:3833206 MGI:5617896 RGD:5129529 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C4A complement C4A (Rodgers blood group) involved_in
acts_upstream_of_or_within
IBA
IDA
ISO
IGI
(PMID:21873635)
(PMID:12878586), (PMID:6906228)
(MGI:51812|PMID:1438267), (MGI:66045|PMID:8133084)
(PMID:19302245)
GO_Central
ComplexPortal
MGI
BHF-UCL
PMID:1438267 PMID:6906228 PMID:8133084 PMID:12878586 PMID:19302245 More... MGI:51812 MGI:66045 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681
JBrowse link
G C4B complement C4B (Chido blood group) involved_in
acts_upstream_of_or_within
IGI
IDA
ISO
IBA
(PMID:19302245)
(PMID:12878586), (PMID:6906228)
(MGI:2429478|PMID:12421924)
(PMID:21873635)
BHF-UCL
ComplexPortal
MGI
GO_Central
PMID:6906228 PMID:12421924 PMID:12878586 PMID:19302245 PMID:21873635 MGI:2429478 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
JBrowse link
G C4B_2 complement component 4B (Chido blood group), copy 2 involved_in IGI
IDA
IBA
(PMID:19302245)
(PMID:12878586), (PMID:6906228)
(PMID:21873635)
BHF-UCL
ComplexPortal
GO_Central
PMID:6906228 PMID:12878586 PMID:19302245 PMID:21873635
G C5 complement C5 involved_in IDA (PMID:2808363) ComplexPortal PMID:2808363 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G C6 complement C6 involved_in IDA (PMID:2808363) ComplexPortal PMID:2808363 NCBI chr 5:41,142,116...41,261,486
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G C7 complement C7 involved_in TAS (PMID:3335508) PINC PMID:3335508 NCBI chr 5:40,909,497...40,984,643
Ensembl chr 5:40,909,497...40,984,643
JBrowse link
G C8A complement C8 alpha chain acts_upstream_of_or_within IDA (PMID:12413696) MGI PMID:12413696 NCBI chr 1:56,854,796...56,918,223
Ensembl chr 1:56,854,797...56,918,223
JBrowse link
G C8B complement C8 beta chain involved_in TAS (PMID:8098723) PINC PMID:8098723 NCBI chr 1:56,929,207...56,974,383
Ensembl chr 1:56,929,207...56,966,140
JBrowse link
G C8G complement C8 gamma chain involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:136,944,870...136,946,981
Ensembl chr 9:136,945,185...136,946,975
JBrowse link
G CFB complement factor B involved_in IEA
ISO
InterPro
RGD
PMID:6906329 GO_REF:0000002 RGD:2311339 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CFD complement factor D involved_in TAS (PMID:1374388) PINC PMID:1374388 NCBI chr19:859,664...863,641
Ensembl chr19:859,664...863,641
JBrowse link
G CFH complement factor H involved_in
acts_upstream_of_or_within
IDA
ISO
(PMID:24835392)
(MGI:3848672|PMID:19411110), (MGI:4821502|PMID:20675597)
(MGI:4830025|PMID:20702729)
(MGI:3639077|PMID:15574507), (MGI:3760048|PMID:17517971), (MGI:3760334|PMID:17921253), (MGI:3849508|PMID:19541934), (MGI:5883383|PMID:28057640)
AgBase
MGI
RGD
PMID:12911541 PMID:15574507 PMID:17517971 PMID:17921253 PMID:19411110 More... MGI:3639077 MGI:3760048 MGI:3760334 MGI:3848672 MGI:3849508 MGI:4821502 MGI:4830025 MGI:5883383 RGD:1599888 NCBI chr 1:196,652,033...196,747,504
Ensembl chr 1:196,652,043...196,747,504
JBrowse link
G CFHR1 complement factor H related 1 involved_in TAS (PMID:1711047) PINC PMID:1711047 NCBI chr 1:196,819,731...196,832,189
Ensembl chr 1:196,819,731...196,832,189
JBrowse link
G CFI complement factor I involved_in ISO (MGI:3773599|PMID:18202746) MGI PMID:18202746 MGI:3773599 NCBI chr 4:109,730,982...109,802,040
Ensembl chr 4:109,740,694...109,801,999
JBrowse link
G CLU clusterin involved_in TAS (PMID:1585460) PINC PMID:1585460 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COLEC11 collectin subfamily member 11 involved_in IDA (PMID:23954398) UniProt PMID:23954398 NCBI chr 2:3,595,112...3,644,644
Ensembl chr 2:3,594,832...3,644,644
JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:4821502|PMID:20675597) MGI PMID:20675597 MGI:4821502 NCBI chr 1:207,645,133...207,723,703
Ensembl chr 1:207,645,113...207,738,416
JBrowse link
G FCN3 ficolin 3 involved_in IDA (PMID:22851708) UniProt PMID:22851708 NCBI chr 1:27,369,110...27,374,852
Ensembl chr 1:27,369,110...27,374,824
JBrowse link
G RGCC regulator of cell cycle involved_in IMP (PMID:19162005) BHF-UCL PMID:19162005 NCBI chr13:41,457,411...41,470,876
Ensembl chr13:41,457,550...41,470,871
JBrowse link
activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFH complement factor H acts_upstream_of_or_within ISO (MGI:4837299|PMID:20813971) MGI PMID:20813971 MGI:4837299 NCBI chr 1:196,652,033...196,747,504
Ensembl chr 1:196,652,043...196,747,504
JBrowse link
complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL645922.1 novel complement component 2 (C2) and complement factor B (CFB) protein involved_in IEA UniProt GO_REF:0000043 Ensembl chr 6:31,927,698...31,952,048 JBrowse link
G C3 complement C3 involved_in IEA UniProt GO_REF:0000043 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C5 complement C5 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G C7 complement C7 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:40,909,497...40,984,643
Ensembl chr 5:40,909,497...40,984,643
JBrowse link
G C8A complement C8 alpha chain involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:56,854,796...56,918,223
Ensembl chr 1:56,854,797...56,918,223
JBrowse link
G C8B complement C8 beta chain involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:56,929,207...56,974,383
Ensembl chr 1:56,929,207...56,966,140
JBrowse link
G C8G complement C8 gamma chain involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:136,944,870...136,946,981
Ensembl chr 9:136,945,185...136,946,975
JBrowse link
G C9 complement C9 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,424,868
JBrowse link
G CFB complement factor B involved_in
acts_upstream_of_or_within
NAS
ISO
IEA
TAS
(PMID:8225386)
(MGI:6100611|PMID:27564415)
(MGI:1096110|PMID:9238044)
UniProt
MGI
Reactome
PMID:8225386 PMID:9238044 PMID:27564415 GO_REF:0000043 MGI:1096110 MGI:6100611 Reactome:R-HSA-173736 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CFD complement factor D involved_in
acts_upstream_of_or_within
TAS
IEA
ISO
(MGI:6100611|PMID:27564415) Reactome
InterPro
MGI
PMID:27564415 GO_REF:0000002 MGI:6100611 Reactome:R-HSA-173736 NCBI chr19:859,664...863,641
Ensembl chr19:859,664...863,641
JBrowse link
G CFH complement factor H involved_in
acts_upstream_of_or_within_negative_effect
IEA
ISO
(MGI:4421084|PMID:19828624)
(MGI:6100611|PMID:27564415)
UniProt
MGI
PMID:19828624 PMID:27564415 GO_REF:0000043 MGI:4421084 MGI:6100611 NCBI chr 1:196,652,033...196,747,504
Ensembl chr 1:196,652,043...196,747,504
JBrowse link
G CFHR5 complement factor H related 5 involved_in NAS (PMID:11058592) UniProt PMID:11058592 NCBI chr 1:196,975,022...197,009,725
Ensembl chr 1:196,977,556...197,009,678
JBrowse link
G CFP complement factor properdin involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:47,623,282...47,630,305
Ensembl chr  X:47,623,172...47,630,305
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IMP (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
G CR2 complement C3d receptor 2 involved_in
acts_upstream_of_or_within_negative_effect
IMP
ISO
(PMID:11981823)
(MGI:4421084|PMID:19828624)
ARUK-UCL
MGI
PMID:11981823 PMID:19828624 MGI:4421084 NCBI chr 1:207,454,328...207,489,892
Ensembl chr 1:207,454,230...207,489,895
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr  X:66,021,738...66,040,092
Ensembl chr  X:66,021,738...66,040,125
JBrowse link
complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC135068.1 novel protein, identical to IGHV4-4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr15:21,742,364...21,742,799 JBrowse link
G APCS amyloid P component, serum involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:159,587,826...159,588,865
Ensembl chr 1:159,587,826...159,588,865
JBrowse link
G C1QA complement C1q A chain involved_in
acts_upstream_of_or_within
IEA
IDA
ISO
(PMID:29449492)
(MGI:2177393|PMID:11901193)
InterPro
ComplexPortal
MGI
PMID:11901193 PMID:29449492 GO_REF:0000002 MGI:2177393 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,636,628...22,639,678
JBrowse link
G C1QB complement C1q B chain involved_in IEA
IDA
(PMID:29449492) InterPro
ComplexPortal
PMID:29449492 GO_REF:0000002 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
JBrowse link
G C1QBP complement C1q binding protein involved_in IEA UniProt GO_REF:0000043 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830
JBrowse link
G C1QC complement C1q C chain involved_in IDA (PMID:29449492) ComplexPortal PMID:29449492 NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,633...22,648,110
JBrowse link
G C1R complement C1r involved_in IEA
TAS
InterPro
Reactome
GO_REF:0000002 Reactome:R-HSA-173623 NCBI chr12:7,080,219...7,092,445
Ensembl chr12:7,080,214...7,092,540
JBrowse link
G C1RL complement C1r subcomponent like involved_in IEA UniProt GO_REF:0000043 NCBI chr12:7,094,554...7,109,214
Ensembl chr12:7,089,587...7,109,238
JBrowse link
G C1S complement C1s involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000043 NCBI chr12:7,060,718...7,071,032
Ensembl chr12:6,988,259...7,071,032
JBrowse link
G C2 complement C2 involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000043 NCBI chr 6:31,897,783...31,945,672
Ensembl chr 6:31,897,785...31,945,672
JBrowse link
G C3 complement C3 involved_in IEA UniProt GO_REF:0000043 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C4A complement C4A (Rodgers blood group) involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681
JBrowse link
G C4B complement C4B (Chido blood group) involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
JBrowse link
G C4B_2 complement component 4B (Chido blood group), copy 2 involved_in IEA UniProt GO_REF:0000043
G C4BPA complement component 4 binding protein alpha involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:207,104,232...207,144,972
Ensembl chr 1:207,104,233...207,144,972
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:207,088,795...207,099,993
Ensembl chr 1:207,088,860...207,099,993
JBrowse link
G C5 complement C5 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G C6 complement C6 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:41,142,116...41,261,486
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G C7 complement C7 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:40,909,497...40,984,643
Ensembl chr 5:40,909,497...40,984,643
JBrowse link
G C8A complement C8 alpha chain involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:56,854,796...56,918,223
Ensembl chr 1:56,854,797...56,918,223
JBrowse link
G C8B complement C8 beta chain involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:56,929,207...56,974,383
Ensembl chr 1:56,929,207...56,966,140
JBrowse link
G C8G complement C8 gamma chain involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:136,944,870...136,946,981
Ensembl chr 9:136,945,185...136,946,975
JBrowse link
G C9 complement C9 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,424,868
JBrowse link
G CD46 CD46 molecule involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,054...207,795,513
JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:207,321,674...207,360,966
Ensembl chr 1:207,321,532...207,386,804
JBrowse link
G CFI complement factor I involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:109,730,982...109,802,040
Ensembl chr 4:109,740,694...109,801,999
JBrowse link
G CLU clusterin involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
G CR2 complement C3d receptor 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:207,454,328...207,489,892
Ensembl chr 1:207,454,230...207,489,895
JBrowse link
G CRP C-reactive protein involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:16367929 PMID:21873635 RGD:1580273 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G IGHA1 immunoglobulin heavy constant alpha 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,707,168...105,708,664
Ensembl chr14:105,703,995...105,708,665
JBrowse link
G IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,586,937...105,588,394
Ensembl chr14:105,583,731...105,588,395
JBrowse link
G IGHD immunoglobulin heavy constant delta involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,838,401...105,845,677
Ensembl chr14:105,836,765...105,845,677
JBrowse link
G IGHE immunoglobulin heavy constant epsilon involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,600,066...105,601,727
Ensembl chr14:105,597,691...105,601,728
JBrowse link
G IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2683928|PMID:6952213)
GO_Central
MGI
PMID:6952213 PMID:21873635 MGI:2683928 NCBI chr14:105,741,473...105,743,070
Ensembl chr14:105,736,343...105,743,071
JBrowse link
G IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,643,203...105,644,789
Ensembl chr14:105,639,559...105,644,790
JBrowse link
G IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,765,914...105,771,405
Ensembl chr14:105,764,503...105,771,405
JBrowse link
G IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,624,476...105,626,065
Ensembl chr14:105,620,506...105,626,066
JBrowse link
G IGHM immunoglobulin heavy constant mu involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,851,966...105,856,217
Ensembl chr14:105,851,705...105,856,218
JBrowse link
G IGHV1-18 immunoglobulin heavy variable 1-18 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,184,899...106,185,335
Ensembl chr14:106,184,901...106,185,394
JBrowse link
G IGHV1-2 immunoglobulin heavy variable 1-2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,986,582...105,987,019
Ensembl chr14:105,986,582...105,987,083
JBrowse link
G IGHV1-24 immunoglobulin heavy variable 1-24 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,276,546...106,276,983
Ensembl chr14:106,276,548...106,277,043
JBrowse link
G IGHV1-3 immunoglobulin heavy variable 1-3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,005,095...106,005,532
Ensembl chr14:106,005,095...106,005,574
JBrowse link
G IGHV1-45 immunoglobulin heavy variable 1-45 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,506,996...106,507,433
Ensembl chr14:106,506,996...106,507,491
JBrowse link
G IGHV1-46 immunoglobulin heavy variable 1-46 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,511,115...106,511,552
Ensembl chr14:106,511,117...106,511,856
JBrowse link
G IGHV1-58 immunoglobulin heavy variable 1-58 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,622,357...106,622,794
Ensembl chr14:106,622,357...106,622,855
JBrowse link
G IGHV1-69 immunoglobulin heavy variable 1-69 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,714,682...106,715,120
Ensembl chr14:106,714,684...106,715,181
JBrowse link
G IGHV1-69-2 immunoglobulin heavy variable 1-69-2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,737,110...106,737,547
Ensembl chr14:106,737,110...106,737,547
JBrowse link
G IGHV1-69D immunoglobulin heavy variable 1-69D involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,762,092...106,762,530
Ensembl chr14:106,762,092...106,762,588
JBrowse link
G IGHV1-8 immunoglobulin heavy variable 1-8 involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV1OR15-1 immunoglobulin heavy variable 1/OR15-1 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:22,160,289...22,160,930
Ensembl chr15:22,160,431...22,160,868
JBrowse link
G IGHV1OR15-9 immunoglobulin heavy variable 1/OR15-9 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:19,964,656...19,965,101
Ensembl chr15:19,964,666...19,965,101
JBrowse link
G IGHV1OR21-1 immunoglobulin heavy variable 1/OR21-1 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:10,649,390...10,649,835
Ensembl chr21:10,649,400...10,649,835
JBrowse link
G IGHV2-26 immunoglobulin heavy variable 2-26 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,301,395...106,301,838
Ensembl chr14:106,301,396...106,301,862
JBrowse link
G IGHV2-5 immunoglobulin heavy variable 2-5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,037,902...106,038,345
Ensembl chr14:106,037,902...106,038,365
JBrowse link
G IGHV2-70 immunoglobulin heavy variable 2-70 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,770,577...106,771,020
Ensembl chr14:106,770,577...106,771,020
JBrowse link
G IGHV2-70D immunoglobulin heavy variable 2-70D involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,723,574...106,724,017
Ensembl chr14:106,723,574...106,724,093
JBrowse link
G IGHV2OR16-5 immunoglobulin heavy variable 2/OR16-5 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:32,847,713...32,848,254
Ensembl chr16:32,847,713...32,848,156
JBrowse link
G IGHV3-11 immunoglobulin heavy variable 3-11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,116,635...106,117,084
Ensembl chr14:106,116,635...106,117,204
JBrowse link
G IGHV3-13 immunoglobulin heavy variable 3-13 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,129,540...106,129,992
Ensembl chr14:106,129,540...106,130,072
JBrowse link
G IGHV3-15 immunoglobulin heavy variable 3-15 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,153,622...106,154,083
Ensembl chr14:106,153,624...106,154,163
JBrowse link
G IGHV3-16 immunoglobulin heavy variable 3-16 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,165,203...106,165,656
Ensembl chr14:106,165,205...106,165,730
JBrowse link
G IGHV3-20 immunoglobulin heavy variable 3-20 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,210,936...106,211,391
Ensembl chr14:106,210,936...106,211,453
JBrowse link
G IGHV3-21 immunoglobulin heavy variable 3-21 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,235,062...106,235,515
Ensembl chr14:106,235,064...106,235,594
JBrowse link
G IGHV3-23 immunoglobulin heavy variable 3-23 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,268,606...106,269,061
Ensembl chr14:106,268,606...106,269,140
JBrowse link
G IGHV3-30 immunoglobulin heavy variable 3-30 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,335,080...106,335,533
Ensembl chr14:106,335,082...106,335,613
JBrowse link
G IGHV3-30-3 immunoglobulin heavy variable 3-30-3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV3-30-5 immunoglobulin heavy variable 3-30-5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV3-33 immunoglobulin heavy variable 3-33 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,359,791...106,360,244
Ensembl chr14:106,359,793...106,360,324
JBrowse link
G IGHV3-35 immunoglobulin heavy variable 3-35 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,389,390...106,389,843
Ensembl chr14:106,389,392...106,389,858
JBrowse link
G IGHV3-38 immunoglobulin heavy variable 3-38 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,410,494...106,410,943
Ensembl chr14:106,410,493...106,411,021
JBrowse link
G IGHV3-43 immunoglobulin heavy variable 3-43 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,470,263...106,470,720
Ensembl chr14:106,470,264...106,470,800
JBrowse link
G IGHV3-48 immunoglobulin heavy variable 3-48 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,537,810...106,538,265
Ensembl chr14:106,537,810...106,538,344
JBrowse link
G IGHV3-49 immunoglobulin heavy variable 3-49 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,556,936...106,557,397
Ensembl chr14:106,556,936...106,557,477
JBrowse link
G IGHV3-53 immunoglobulin heavy variable 3-53 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,592,676...106,593,126
Ensembl chr14:106,592,676...106,593,347
JBrowse link
G IGHV3-64 immunoglobulin heavy variable 3-64 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,657,723...106,658,178
Ensembl chr14:106,657,725...106,658,258
JBrowse link
G IGHV3-64D immunoglobulin heavy variable 3-64D involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,088,122...106,088,573
Ensembl chr14:106,088,122...106,088,573
JBrowse link
G IGHV3-66 immunoglobulin heavy variable 3-66 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,675,015...106,675,465
Ensembl chr14:106,675,017...106,675,544
JBrowse link
G IGHV3-7 immunoglobulin heavy variable 3-7 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,062,149...106,062,604
Ensembl chr14:106,062,151...106,062,683
JBrowse link
G IGHV3-72 immunoglobulin heavy variable 3-72 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,790,692...106,791,153
Ensembl chr14:106,790,694...106,791,233
JBrowse link
G IGHV3-73 immunoglobulin heavy variable 3-73 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,802,692...106,803,153
Ensembl chr14:106,802,694...106,803,233
JBrowse link
G IGHV3-74 immunoglobulin heavy variable 3-74 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,810,440...106,810,895
Ensembl chr14:106,810,442...106,811,131
JBrowse link
G IGHV3-9 immunoglobulin heavy variable 3-9 involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV3OR15-7 immunoglobulin heavy variable 3/OR15-7 (pseudogene) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr15:19,987,656...19,988,117 JBrowse link
G IGHV3OR16-10 immunoglobulin heavy variable 3/OR16-10 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:32,995,213...32,995,503
Ensembl chr16:32,995,048...32,995,505
JBrowse link
G IGHV3OR16-12 immunoglobulin heavy variable 3/OR16-12 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,802,922...33,803,215
Ensembl chr16:33,802,764...33,803,217
JBrowse link
G IGHV3OR16-13 immunoglobulin heavy variable 3/OR16-13 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,827,366...33,827,659
Ensembl chr16:33,827,214...33,827,661
JBrowse link
G IGHV3OR16-17 immunoglobulin heavy variable 3/OR16-17 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,844,758...33,845,274
Ensembl chr16:33,844,784...33,845,229
JBrowse link
G IGHV3OR16-8 immunoglobulin heavy variable 3/OR16-8 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:33,009,124...33,009,646
Ensembl chr16:33,009,175...33,009,620
JBrowse link
G IGHV4-28 immunoglobulin heavy variable 4-28 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,324,254...106,324,688
Ensembl chr14:106,324,254...106,324,760
JBrowse link
G IGHV4-30-2 immunoglobulin heavy variable 4-30-2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,349,283...106,349,720 JBrowse link
G IGHV4-30-4 immunoglobulin heavy variable 4-30-4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV4-31 immunoglobulin heavy variable 4-31 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,349,283...106,349,720
Ensembl chr14:106,349,283...106,349,792
JBrowse link
G IGHV4-34 immunoglobulin heavy variable 4-34 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,373,661...106,374,093
Ensembl chr14:106,373,663...106,374,145
JBrowse link
G IGHV4-38-2 immunoglobulin heavy variable 4-38-2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G IGHV4-39 immunoglobulin heavy variable 4-39 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,421,709...106,422,147
Ensembl chr14:106,421,711...106,422,218
JBrowse link
G IGHV4-4 immunoglobulin heavy variable 4-4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,011,922...106,012,356
Ensembl chr14:106,011,922...106,012,420
JBrowse link
G IGHV4-59 immunoglobulin heavy variable 4-59 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,627,249...106,627,680
Ensembl chr14:106,627,249...106,627,825
JBrowse link
G IGHV4-61 immunoglobulin heavy variable 4-61 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,639,119...106,639,556
Ensembl chr14:106,639,119...106,639,657
JBrowse link
G IGHV4OR15-8 immunoglobulin heavy variable 4/OR15-8 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr15:22,184,967...22,185,402 JBrowse link
G IGHV5-10-1 immunoglobulin heavy variable 5-10-1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,107,972...106,108,513
Ensembl chr14:106,107,972...106,108,464
JBrowse link
G IGHV5-51 immunoglobulin heavy variable 5-51 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,578,742...106,579,177
Ensembl chr14:106,578,744...106,579,236
JBrowse link
G IGHV6-1 immunoglobulin heavy variable 6-1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:105,939,754...105,940,201
Ensembl chr14:105,939,756...105,940,253
JBrowse link
G IGHV7-4-1 immunoglobulin heavy variable 7-4-1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,025,145...106,025,581
Ensembl chr14:106,025,145...106,025,630
JBrowse link
G IGHV7-81 immunoglobulin heavy variable 7-81 (non-functional) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:106,874,581...106,875,017
Ensembl chr14:106,874,583...106,875,071
JBrowse link
G IGKC immunoglobulin kappa constant involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:88,857,361...88,857,683
Ensembl chr 2:88,857,161...88,857,683
JBrowse link
G IGLC1 immunoglobulin lambda constant 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,895,375...22,895,694
Ensembl chr22:22,895,375...22,895,834
JBrowse link
G IGLC2 immunoglobulin lambda constant 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,900,976...22,901,295
Ensembl chr22:22,900,976...22,901,437
JBrowse link
G IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,906,342...22,906,661
Ensembl chr22:22,906,342...22,906,803
JBrowse link
G IGLC6 immunoglobulin lambda constant 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,919,535...22,919,858
Ensembl chr22:22,919,535...22,919,851
JBrowse link
G IGLC7 immunoglobulin lambda constant 7 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,922,594...22,922,913
Ensembl chr22:22,922,594...22,923,034
JBrowse link
G IGLL1 immunoglobulin lambda like polypeptide 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:23,573,125...23,580,290
Ensembl chr22:23,573,125...23,580,302
JBrowse link
G IGLL5 immunoglobulin lambda like polypeptide 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr22:22,887,816...22,896,111
Ensembl chr22:22,887,780...22,896,111
JBrowse link
G MASP2 MBL associated serine protease 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:11,026,523...11,047,239
Ensembl chr 1:11,026,523...11,047,239
JBrowse link
G MBL2 mannose binding lectin 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
JBrowse link
G SUSD4 sushi domain containing 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:223,220,826...223,365,271
Ensembl chr 1:223,220,819...223,364,233
JBrowse link
G TRBC1 T cell receptor beta constant 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,791,694...142,793,141
Ensembl chr 7:142,791,694...142,793,368
JBrowse link
G TRBC2 T cell receptor beta constant 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,801,041...142,802,529
Ensembl chr 7:142,801,041...142,802,748
JBrowse link
G TRDC T cell receptor delta constant involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:22,462,932...22,466,577
Ensembl chr14:22,462,932...22,465,787
JBrowse link
complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COLEC10 collectin subfamily member 10 involved_in IDA (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 8:118,952,233...119,108,455
Ensembl chr 8:118,995,452...119,108,455
JBrowse link
G COLEC11 collectin subfamily member 11 involved_in IMP
IDA
(PMID:25912189)
(PMID:24174618)
UniProt
ComplexPortal
PMID:24174618 PMID:25912189 NCBI chr 2:3,595,112...3,644,644
Ensembl chr 2:3,594,832...3,644,644
JBrowse link
G FCN1 ficolin 1 involved_in IBA
IDA
(PMID:21873635)
(PMID:16116205)
GO_Central
ComplexPortal
PMID:16116205 PMID:21873635 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912
JBrowse link
G FCN2 ficolin 2 involved_in IBA
IDA
(PMID:21873635)
(PMID:10679061), (PMID:14707097), (PMID:15804047)
GO_Central
UniProt
PMID:10679061 PMID:14707097 PMID:15804047 PMID:21873635 NCBI chr 9:134,864,062...134,890,506
Ensembl chr 9:134,880,810...134,887,523
JBrowse link
G FCN3 ficolin 3 involved_in
acts_upstream_of_or_within
IDA
ISO
(PMID:11907111)
(MGI:5473786|PMID:16328467)
UniProt
MGI
PMID:11907111 PMID:16328467 MGI:5473786 NCBI chr 1:27,369,110...27,374,852
Ensembl chr 1:27,369,110...27,374,824
JBrowse link
G KRT1 keratin 1 involved_in IPI (PMID:11549596) UniProt PMID:11549596 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in IMP
IDA
IBA
(PMID:17182967)
(PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22691502), (PMID:24174618)
(PMID:21873635)
UniProt
ComplexPortal
GO_Central
PMID:10679061 PMID:11907111 PMID:16116205 PMID:17182967 PMID:21873635 More... NCBI chr 3:187,217,282...187,293,529
Ensembl chr 3:187,217,282...187,291,980
JBrowse link
G MASP2 MBL associated serine protease 2 involved_in
acts_upstream_of_or_within
IBA
IDA
ISO
(PMID:21873635)
(PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:17182967), (PMID:22691502), (PMID:24174618), (PMID:9087411)
(MGI:5473786|PMID:16328467)
GO_Central
ComplexPortal
MGI
PMID:9087411 PMID:10679061 PMID:11907111 PMID:16116205 PMID:16328467 More... MGI:5473786 NCBI chr 1:11,026,523...11,047,239
Ensembl chr 1:11,026,523...11,047,239
JBrowse link
G MBL1P mannose binding lectin 1, pseudogene acts_upstream_of_or_within ISO (MGI:3577322|PMID:15148336) RGD
MGI
PMID:15148336 PMID:16272342 MGI:3577322 RGD:1582134 NCBI chr10:79,920,178...79,923,119
Ensembl chr10:79,920,178...79,923,119
JBrowse link
G MBL2 mannose binding lectin 2 involved_in
acts_upstream_of_or_within
IPI
IDA
(PMID:11549596)
(PMID:22691502)
(PMID:15148336)
UniProt
ComplexPortal
MGI
PMID:11549596 PMID:15148336 PMID:22691502 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MFAP4 microfibril associated protein 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190
JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL049629.2 novel protein involved_in IEA InterPro GO_REF:0000002 Ensembl chr11:33,698,261...33,722,467 JBrowse link
G CD59 CD59 molecule (CD59 blood group) involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
(PMID:21873635)
InterPro
MGI
RGD
GO_Central
PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635 GO_REF:0000002 MGI:1888643 MGI:2148385 RGD:1600482 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of IDA (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) involved_in IDA
ISO
IMP
(PMID:6211481)
(PMID:28657829)
UniProt
RGD
PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chr 1:207,321,674...207,360,966
Ensembl chr 1:207,321,532...207,386,804
JBrowse link
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279) MGI PMID:10946279 MGI:1888643 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IDA (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:1351571|PMID:10642554) RGD
MGI
PMID:10642554 PMID:11861390 MGI:1351571 RGD:625470 NCBI chr 1:207,645,133...207,723,703
Ensembl chr 1:207,645,113...207,738,416
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in IDA (PMID:11485744) UniProt PMID:11485744 NCBI chr 3:187,217,282...187,293,529
Ensembl chr 3:187,217,282...187,291,980
JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,054...207,795,513
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IDA (PMID:10531307) UniProt PMID:10531307 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
G SUSD4 sushi domain containing 4 involved_in IBA
IDA
(PMID:21873635)
(PMID:23482636)
GO_Central
UniProt
PMID:21873635 PMID:23482636 NCBI chr 1:223,220,826...223,365,271
Ensembl chr 1:223,220,819...223,364,233
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in IPI
IBA
(PMID:17051150)
(PMID:21873635)
UniProt
GO_Central
PMID:17051150 PMID:21873635 NCBI chr  X:66,021,738...66,040,092
Ensembl chr  X:66,021,738...66,040,125
JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IDA
IBA
(PMID:22333221)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21873635 PMID:22333221 NCBI chr 1:207,104,232...207,144,972
Ensembl chr 1:207,104,233...207,144,972
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IDA (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 1:207,088,795...207,099,993
Ensembl chr 1:207,088,860...207,099,993
JBrowse link
G CD46 CD46 molecule involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,054...207,795,513
JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:207,321,674...207,360,966
Ensembl chr 1:207,321,532...207,386,804
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IDA
IBA
(PMID:10531307), (PMID:6910481)
(PMID:21873635)
UniProt
GO_Central
PMID:6910481 PMID:10531307 PMID:21873635 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
G CR1L complement C3b/C4b receptor 1 like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:207,645,133...207,723,703
Ensembl chr 1:207,645,113...207,738,416
JBrowse link
G CR2 complement C3d receptor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:207,454,328...207,489,892
Ensembl chr 1:207,454,230...207,489,895
JBrowse link
G SUSD4 sushi domain containing 4 involved_in IDA
IBA
(PMID:23482636)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:23482636 NCBI chr 1:223,220,826...223,365,271
Ensembl chr 1:223,220,819...223,364,233
JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin involved_in IDA (PMID:12538697) UniProt PMID:12538697 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G SERPING1 serpin family G member 1 involved_in IDA (PMID:10946292) UniProt PMID:10946292 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:41,142,116...41,261,486
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in IMP (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:207,496,157...207,641,765
Ensembl chr 1:207,496,147...207,641,765
JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:41,142,116...41,261,486
Ensembl chr 5:41,142,116...41,261,438
JBrowse link
G IL1B interleukin 1 beta involved_in IGI (PMID:29384235) ARUK-UCL PMID:29384235 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G MBL2 mannose binding lectin 2 ISO RGD PMID:9920905 RGD:4889148 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G PHB1 prohibitin 1 involved_in IDA (PMID:17070910) UniProt PMID:17070910 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,052...49,414,901
JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
JBrowse link
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IBA
IDA
(PMID:21873635)
(PMID:8195709)
GO_Central
UniProt
PMID:8195709 PMID:21873635 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830
JBrowse link
G C3 complement C3 involved_in IDA (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C8B complement C8 beta chain involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:56,929,207...56,974,383
Ensembl chr 1:56,929,207...56,966,140
JBrowse link
G CD55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within IDA (PMID:25284781) MGI PMID:25284781 NCBI chr 1:207,321,674...207,360,966
Ensembl chr 1:207,321,532...207,386,804
JBrowse link
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within IDA (PMID:25284781) MGI PMID:25284781 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
JBrowse link
G CD5L CD5 molecule like involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5617896|PMID:25284781) Ensembl
MGI
PMID:25284781 GO_REF:0000107 MGI:5617896 NCBI chr 1:157,827,068...157,841,844
Ensembl chr 1:157,830,911...157,898,256
JBrowse link
G CFH complement factor H acts_upstream_of_or_within ISO
IDA
(PMID:25284781) RGD
MGI
PMID:12374811 PMID:25284781 RGD:628500 NCBI chr 1:196,652,033...196,747,504
Ensembl chr 1:196,652,043...196,747,504
JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within IDA (PMID:25284781) MGI PMID:25284781 NCBI chr 1:207,645,133...207,723,703
Ensembl chr 1:207,645,113...207,738,416
JBrowse link
G PHB2 prohibitin 2 NOT|involved_in IDA (PMID:17070910) UniProt PMID:17070910 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780
JBrowse link
G SUSD4 sushi domain containing 4 involved_in IEA
IDA
(PMID:23482636) InterPro
UniProt
PMID:23482636 GO_REF:0000002 NCBI chr 1:223,220,826...223,365,271
Ensembl chr 1:223,220,819...223,364,233
JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IDA (PMID:28671664) ComplexPortal PMID:28671664 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CFH complement factor H involved_in IDA (PMID:20378178), (PMID:28671664) ComplexPortal PMID:20378178 PMID:28671664 NCBI chr 1:196,652,033...196,747,504
Ensembl chr 1:196,652,043...196,747,504
JBrowse link
G CFI complement factor I involved_in IDA (PMID:28671664) ComplexPortal PMID:28671664 NCBI chr 4:109,730,982...109,802,040
Ensembl chr 4:109,740,694...109,801,999
JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (MGI:1330710|PMID:9892684) MGI PMID:9892684 MGI:1330710 NCBI chr 1:207,321,674...207,360,966
Ensembl chr 1:207,321,532...207,386,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18607
    immune system process 3106
      immune effector process 746
        complement activation 147
          activation of membrane attack complex + 6
          complement activation, alternative pathway + 19
          complement activation, classical pathway + 122
          complement activation, lectin pathway + 13
          negative regulation of complement activation + 14
          positive regulation of complement activation + 7
          regulation of complement activation + 26
Path 2
Term Annotations click to browse term
  biological_process 18607
    biological regulation 13187
      regulation of biological process 12471
        positive regulation of biological process 6886
          positive regulation of response to stimulus 2409
            positive regulation of immune response 667
              activation of immune response 437
                complement activation 147
                  activation of membrane attack complex + 6
                  complement activation, alternative pathway + 19
                  complement activation, classical pathway + 122
                  complement activation, lectin pathway + 13
                  negative regulation of complement activation + 14
                  positive regulation of complement activation + 7
                  regulation of complement activation + 26
paths to the root