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ONTOLOGY REPORT - ANNOTATIONS


Term:striated muscle contraction
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Accession:GO:0006941 term browser browse the term
Definition:A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.
Synonyms:exact_synonym: sarcomeric muscle contraction
 xref: MIPS_funcat:36.25.09.03


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striated muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldoa aldolase, fructose-bisphosphate A JBrowse link 1 198,228,387 198,233,988 RGD:1624291
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1624291
RGD:1600115
G Cacna1s calcium voltage-gated channel subunit alpha1 S JBrowse link 13 52,889,570 52,964,558 RGD:1624291
G Gaa glucosidase, alpha, acid JBrowse link 10 108,395,873 108,412,999 RGD:1624291
G Lmod3 leiomodin 3 JBrowse link 4 129,604,378 129,619,136 RGD:1624291
RGD:1600115
G Myh1 myosin heavy chain 1 JBrowse link 10 53,740,841 53,764,610 RGD:1302818
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:1624291
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1624291
G Mylk2 myosin light chain kinase 2 JBrowse link 3 148,386,185 148,397,851 RGD:1624291
RGD:13792537
RGD:1600115
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1624291
RGD:1600115
G Pgam2 phosphoglycerate mutase 2 JBrowse link 14 86,045,005 86,047,116 RGD:1624291
RGD:1600115
G Ryr3 ryanodine receptor 3 JBrowse link 3 104,117,307 104,665,151 RGD:1624291
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:1624291
atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
RGD:1600115
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
RGD:1600115
G Nup155 nucleoporin 155 JBrowse link 2 57,206,665 57,258,242 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
cardiac muscle cell action potential involved in contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:1600115
RGD:1624291
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:1600115
RGD:1624291
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:1624291
RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
RGD:1600115
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:1600115
RGD:1624291
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
RGD:13792537
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:13792537
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
cardiac muscle cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:8656014
G Sgcd sarcoglycan, delta JBrowse link 10 32,062,946 32,471,454 RGD:1624291
RGD:1600115
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:7349316
G Uty ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome JBrowse link Y 1,065,274 1,206,127 RGD:1624291
cardiac muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:1600569
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:6903343
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 JBrowse link 1 81,852,423 81,881,565 RGD:1624291
RGD:1600115
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 JBrowse link 13 82,737,161 82,757,681 RGD:1624291
RGD:1600115
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:1624291
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:1624291
RGD:1600115
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:1624291
RGD:13792537
RGD:1600115
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:1600772
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
G Gaa glucosidase, alpha, acid JBrowse link 10 108,395,873 108,412,999 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:1624291
RGD:1600115
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:1624291
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:1624291
RGD:1600115
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1624291
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
RGD:1600115
G Mybpc3 myosin binding protein C, cardiac JBrowse link 3 79,940,509 79,958,731 RGD:8553425
RGD:1624291
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:1624291
RGD:1600115
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1624291
RGD:1600115
G Myl1 myosin, light chain 1 JBrowse link 9 73,937,820 73,958,480 RGD:1600167
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:1600167
RGD:1600115
RGD:1624291
RGD:1600178
RGD:1600170
G Myl3 myosin light chain 3 JBrowse link 8 119,030,852 119,036,996 RGD:1598726
RGD:1624291
RGD:1600304
G Myl4 myosin, light chain 4 JBrowse link 10 92,628,356 92,638,100 RGD:1600115
RGD:1624291
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Ppp1r13l protein phosphatase 1, regulatory subunit 13 like JBrowse link 1 80,271,288 80,290,946 RGD:1624291
RGD:1600115
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:1624291
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
G Scn4b sodium voltage-gated channel beta subunit 4 JBrowse link 8 49,441,106 49,456,279 RGD:1624291
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1600115
RGD:1624291
G Sgcd sarcoglycan, delta JBrowse link 10 32,062,946 32,471,454 RGD:1624291
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:1624291
G Smad5 SMAD family member 5 JBrowse link 17 8,307,448 8,336,996 RGD:1624291
RGD:1600115
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:1624291
RGD:1600115
G Taz tafazzin JBrowse link X 156,421,006 156,429,461 RGD:1624291
RGD:1600115
G Tcap titin-cap JBrowse link 10 86,337,705 86,338,414 RGD:1624291
G Tnnc1 troponin C1, slow skeletal and cardiac type JBrowse link 16 7,292,207 7,295,238 RGD:1600167
RGD:1624291
G Tnni1 troponin I1, slow skeletal type JBrowse link 13 52,624,856 52,637,297 RGD:13792537
G Tnni2 troponin I2, fast skeletal type JBrowse link 1 215,609,110 215,611,652 RGD:13792537
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:1600167
RGD:13792537
RGD:1624291
RGD:1600569
RGD:1600178
G Tnnt1 troponin T1, slow skeletal type JBrowse link 1 72,889,270 72,899,629 RGD:13792537
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:1600178
RGD:13792537
RGD:1624291
G Tnnt3 troponin T3, fast skeletal type JBrowse link 1 215,666,628 215,683,628 RGD:13792537
G Tpm1 tropomyosin 1 JBrowse link 8 72,814,737 72,841,496 RGD:1600569
RGD:13792537
RGD:1600115
RGD:1624291
G Tpm1_v1 tropomyosin 1, variant 1 RGD:1600569
G Tpm1_v2 tropomyosin 1, variant 2 RGD:1600569
G Tpm1_v3 tropomyosin 1, variant 3 RGD:1600569
G Tpm1_v4 tropomyosin 1, variant 4 RGD:1600569
G Tpm1_v5 tropomyosin 1, variant 5 RGD:1600569
G Tpm1_v6 tropomyosin 1, variant 6 RGD:1600569
G Tpm1_v7 tropomyosin 1, variant 7 RGD:1600569
G Tpm1_v8 tropomyosin 1, variant 8 RGD:1600569
G Tpm1_v9 tropomyosin 1, variant 9 RGD:1600569
G Ttn titin JBrowse link 3 63,565,160 63,837,815 RGD:1624291
G Vegfb vascular endothelial growth factor B JBrowse link 1 222,237,000 222,242,786 RGD:1624291
diaphragm contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:4145100
G Gaa glucosidase, alpha, acid JBrowse link 10 108,395,873 108,412,999 RGD:1624291
RGD:1600115
G Tnnc1 troponin C1, slow skeletal and cardiac type JBrowse link 16 7,292,207 7,295,238 RGD:1598612
fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Synm synemin JBrowse link 1 128,692,112 128,722,048 RGD:1624291
involuntary skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp8a2 ATPase phospholipid transporting 8A2 JBrowse link 15 39,955,689 40,488,737 RGD:1624291
RGD:1600115
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
membrane repolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:1624291
RGD:1600115
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:1624291
RGD:1600115
G Kcnn2 potassium calcium-activated channel subfamily N member 2 JBrowse link 18 39,331,894 39,479,574 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1600115
RGD:1624291
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnd3 potassium voltage-gated channel subfamily D member 3 JBrowse link 2 207,923,775 208,140,727 RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
RGD:1600115
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1600115
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:1600115
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1600115
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
RGD:1600115
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 JBrowse link 4 176,783,287 176,789,143 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
RGD:1600115
negative regulation of cardiac muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1624291
RGD:1600115
negative regulation of striated muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1582129
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:1624291
RGD:1600115
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:1624291
RGD:1600115
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:10003031
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1600115
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:7205486
positive regulation of cardiac muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace2 angiotensin I converting enzyme 2 JBrowse link X 32,050,734 32,095,860 RGD:1624291
RGD:1600115
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:5688340
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:2314476
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:6906968
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:5686387
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
RGD:1600115
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:1624291
RGD:1600115
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:1624291
RGD:1600115
G Smtn smoothelin JBrowse link 14 83,755,141 83,776,871 RGD:1624291
RGD:1600115
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:5508168
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
RGD:1600115
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1624291
RGD:1600115
G Mylk2 myosin light chain kinase 2 JBrowse link 3 148,386,185 148,397,851 RGD:1580242
positive regulation of striated muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
RGD:1600115
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf207 ring finger protein 207 JBrowse link 5 169,486,253 169,500,451 RGD:1624291
RGD:1600115
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:1624291
RGD:1600115
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10047146
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:10047271
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
G Fgf13 fibroblast growth factor 13 JBrowse link X 142,053,648 142,589,274 RGD:1624291
RGD:1600115
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:1600115
RGD:1624291
G Rangrf RAN guanine nucleotide release factor JBrowse link 10 55,559,049 55,560,420 RGD:1624291
RGD:1600115
regulation of cardiac muscle cell contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317914
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6893639
RGD:2317914
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:8553373
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:6903236
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:2314601
G Fxyd1 FXYD domain-containing ion transport regulator 1 JBrowse link 1 89,484,197 89,488,279 RGD:9685468
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:7207043
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:7247430
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:1624291
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:7327160
RGD:13792537
RGD:1624291
RGD:1600115
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:1624291
RGD:1600115
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1624291
RGD:1600115
regulation of cardiac muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:2317910
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:1600115
G Agrn agrin JBrowse link 5 173,589,910 173,622,813 RGD:1624291
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Bmp10 bone morphogenetic protein 10 JBrowse link 4 119,224,906 119,230,534 RGD:1624291
RGD:1600115
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1624291
RGD:1600115
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
G Ehd3 EH-domain containing 3 JBrowse link 6 25,076,012 25,102,457 RGD:1600115
RGD:1624291
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:1624291
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link 8 128,298,593 128,416,896 RGD:1624291
RGD:1600115
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1624291
RGD:1600115
G Tnni3k TNNI3 interacting kinase JBrowse link 2 261,069,210 261,337,294 RGD:1624291
RGD:1600115
regulation of cardiac muscle contraction by calcium ion signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 JBrowse link 13 82,737,161 82,757,681 RGD:1624291
RGD:1600115
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:1624291
RGD:13792537
RGD:10047146
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:1624291
RGD:1600115
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:1624291
RGD:1600115
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Asph aspartate-beta-hydroxylase JBrowse link 5 22,577,680 22,799,333 RGD:1624291
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1600115
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:10047271
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:2314601
RGD:13792537
RGD:1624291
RGD:1600115
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
RGD:1600115
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:13792537
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:8554732
G Tmem38a transmembrane protein 38a JBrowse link 16 18,960,197 18,974,942 RGD:1624291
RGD:1600115
G Tmem38b transmembrane protein 38B JBrowse link 5 70,639,156 70,675,055 RGD:1624291
RGD:1600115
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin JBrowse link 1 225,035,956 225,046,137 RGD:1624291
G Dmpk DM1 protein kinase JBrowse link 1 79,988,096 79,999,358 RGD:1624291
RGD:1600115
regulation of skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
G Grcc10 gene rich cluster, C10 gene JBrowse link 4 157,264,383 157,266,042 RGD:1624291
G Slc8a3 solute carrier family 8 member A3 JBrowse link 6 104,889,500 105,099,408 RGD:1624291
RGD:1600115
regulation of skeletal muscle contraction by action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scn4a sodium voltage-gated channel alpha subunit 4 JBrowse link 10 94,505,026 94,557,803 RGD:1600115
RGD:1624291
regulation of skeletal muscle contraction by calcium ion signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmpk DM1 protein kinase JBrowse link 1 79,988,096 79,999,358 RGD:1624291
RGD:13792537
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casq1 calsequestrin 1 JBrowse link 13 90,592,676 90,602,365 RGD:1600115
RGD:13792537
RGD:1624291
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
RGD:1600115
regulation of skeletal muscle contraction via regulation of action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:1624291
RGD:1600115
regulation of slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1624291
RGD:1600115
regulation of striated muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:1624291
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1624291
RGD:1600115
G Mybpc3 myosin binding protein C, cardiac JBrowse link 3 79,940,509 79,958,731 RGD:8553425
G Myl3 myosin light chain 3 JBrowse link 8 119,030,852 119,036,996 RGD:1624291
G Tnnt3 troponin T3, fast skeletal type JBrowse link 1 215,666,628 215,683,628 RGD:1599483
RGD:1600115
RGD:1624291
regulation of the force of skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
RGD:1600115
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1624291
RGD:1600115
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1600115
RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ctnna3 catenin alpha 3 JBrowse link 20 25,063,124 26,640,428 RGD:1624291
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
G Dsc2 desmocollin 2 JBrowse link 18 11,826,705 11,858,801 RGD:1624291
RGD:1600115
G Dsg2 desmoglein 2 JBrowse link 18 15,579,322 15,637,720 RGD:1624291
RGD:1600115
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1624291
RGD:1600115
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:1624291
RGD:1600115
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1600115
RGD:1624291
skeletal muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:13782070
G Ccdc78 coiled-coil domain containing 78 JBrowse link 10 15,155,839 15,160,039 RGD:1624291
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit JBrowse link 3 60,445,657 60,460,724 RGD:1624291
RGD:8549758
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit JBrowse link 10 56,390,671 56,403,255 RGD:8549758
G Chrnd cholinergic receptor nicotinic delta subunit JBrowse link 9 94,286,550 94,294,968 RGD:8549758
G Chrne cholinergic receptor nicotinic epsilon subunit JBrowse link 10 57,238,960 57,246,750 RGD:8549758
G Chrng cholinergic receptor nicotinic gamma subunit JBrowse link 9 94,302,218 94,308,591 RGD:8549758
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:2298664
G Eef2 eukaryotic translation elongation factor 2 JBrowse link 7 11,401,501 11,406,771 RGD:10401231
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:1624291
RGD:1600115
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:5686398
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:2298664
G Jsrp1 junctional sarcoplasmic reticulum protein 1 JBrowse link 7 11,769,950 11,774,373 RGD:1624291
RGD:13792537
G Myh14 myosin heavy chain 14 JBrowse link 1 100,608,975 100,671,086 RGD:1624291
RGD:1600115
G Myh3 myosin heavy chain 3 JBrowse link 10 53,621,375 53,645,194 RGD:1624291
RGD:1600115
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1624291
RGD:1600115
G Myh8 myosin heavy chain 8 JBrowse link 10 53,818,818 53,848,490 RGD:1624291
RGD:1600115
G Rcsd1 RCSD domain containing 1 JBrowse link 13 83,854,650 83,917,040 RGD:8693359
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1643024
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:13792537
G Stac2 SH3 and cysteine rich domain 2 JBrowse link 10 85,988,367 86,004,209 RGD:13792537
G Stac3 SH3 and cysteine rich domain 3 JBrowse link 7 70,807,427 70,815,271 RGD:1624291
RGD:13792537
G Tcap titin-cap JBrowse link 10 86,337,705 86,338,414 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144081
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4144081
G Tnnc1 troponin C1, slow skeletal and cardiac type JBrowse link 16 7,292,207 7,295,238 RGD:13792537
G Tnnc2 troponin C2, fast skeletal type JBrowse link 3 161,243,607 161,246,335 RGD:1624291
RGD:13792537
G Tnni1 troponin I1, slow skeletal type JBrowse link 13 52,624,856 52,637,297 RGD:13792537
G Tnni2 troponin I2, fast skeletal type JBrowse link 1 215,609,110 215,611,652 RGD:1624291
RGD:13792537
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:13792537
G Tnnt1 troponin T1, slow skeletal type JBrowse link 1 72,889,270 72,899,629 RGD:1624291
RGD:13792537
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:13792537
G Tnnt3 troponin T3, fast skeletal type JBrowse link 1 215,666,628 215,683,628 RGD:1624291
RGD:1600115
RGD:13792537
slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mb myoglobin JBrowse link 7 118,101,633 118,108,864 RGD:1582404
G Tnnt1 troponin T1, slow skeletal type JBrowse link 1 72,889,270 72,899,629 RGD:1599482
ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
RGD:1600115
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:8553349
G Gja5 gap junction protein, alpha 5 JBrowse link 2 199,162,745 199,184,942 RGD:1624291
RGD:1600115
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like JBrowse link 8 122,957,570 122,987,236 RGD:1624291
RGD:1600115
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1624291
RGD:13792537
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:1624291
RGD:13792537
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:13792537
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 JBrowse link 9 84,688,873 84,693,066 RGD:13792537
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 JBrowse link X 113,583,844 113,584,459 RGD:1624291
RGD:13792537
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1624291
G Nedd4l NEDD4 like E3 ubiquitin protein ligase JBrowse link 18 60,392,376 60,719,720 RGD:8553349
G Pkp2 plakophilin 2 JBrowse link 11 88,912,163 88,972,213 RGD:1624291
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Scn3b sodium voltage-gated channel beta subunit 3 JBrowse link 8 44,136,413 44,159,011 RGD:1624291
RGD:13792537
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:1624291
G Snta1 syntrophin, alpha 1 JBrowse link 3 149,874,023 149,905,980 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    multicellular organismal process 8641
      system process 3289
        muscle system process 445
          muscle contraction 321
            striated muscle contraction 183
              cardiac muscle contraction + 141
              negative regulation of striated muscle contraction + 9
              positive regulation of striated muscle contraction + 17
              regulation of striated muscle contraction + 89
              skeletal muscle contraction + 50
              striated muscle contraction involved in embryonic body morphogenesis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.