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ONTOLOGY REPORT - ANNOTATIONS

Term:smooth muscle contraction
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Accession:GO:0006939 term browser browse the term
Definition:A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
Synonyms:exact_synonym: visceral muscle contraction


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smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:18340377)		 Ensembl
RGD		 PMID:18340377 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:88398|MGI:98496 (PMID:12925702)		 Ensembl
RGD		 PMID:12925702 GO_REF:0000107 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5648704|PMID:25757569)		 UniProt
RGD		 PMID:25757569 GO_REF:0000024 MGI:5648704 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627 		JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 involved_in ISO (MGI:5648704|PMID:25757569) RGD PMID:25757569 MGI:5648704 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495 		JBrowse link
G Bdkrb2 bradykinin receptor B2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C acts_upstream_of_or_within ISO MGI:2389040|MGI:2674119 (PMID:16636102) RGD PMID:16636102 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Calca calcitonin-related polypeptide alpha acts_upstream_of ISO (PMID:9322931) RGD PMID:9322931 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:12925702)
MGI:1888740 (PMID:10944224)		 RGD PMID:10944224 PMID:12925702 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:87892 (PMID:10531434) RGD PMID:10531434 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit acts_upstream_of_or_within ISO MGI:87891 (PMID:10531434) RGD PMID:10531434 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of ISO (PMID:8010105) RGD PMID:8010105 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 acts_upstream_of ISO (PMID:2768235) RGD PMID:2768235 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B acts_upstream_of_or_within ISO MGI:2182644 (PMID:14592808) RGD PMID:14592808 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Myh11 myosin heavy chain 11 acts_upstream_of_or_within ISO MGI:2656492|MGI:3576856 (PMID:10854329), (PMID:11715025), (PMID:12562924) RGD PMID:10854329 PMID:11715025 PMID:12562924 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459 		JBrowse link
G Mylk myosin light chain kinase involved_in ISO (MGI:3820013|PMID:18586037) RGD PMID:18586037 MGI:3820013 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of ISO MGI:1934143 (PMID:17993584) RGD PMID:17993584 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nmur1 neuromedin U receptor 1 involved_in ISO
IEA		 (PMID:10899166)
GO_REF:0000107		 RGD
Ensembl		 PMID:10899166 GO_REF:0000107 NCBI chr 9:87,033,231...87,038,070
Ensembl chr 9:87,033,279...87,036,684 		JBrowse link
G Pde4b phosphodiesterase 4B NOT|acts_upstream_of_or_within ISO MGI:2181444 (PMID:14519662) RGD PMID:14519662 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D acts_upstream_of_or_within ISO MGI:2451168 (PMID:14519662) RGD PMID:14519662 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Tbxa2r thromboxane A2 receptor acts_upstream_of ISO (PMID:12925702) RGD PMID:12925702 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176 		JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO (MGI:4838733|PMID:20547763) RGD PMID:20547763 MGI:4838733 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236 		JBrowse link
artery smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21076237 RGD:5129195 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 acts_upstream_of_or_within ISO MGI:3521669 (PMID:20852044) RGD PMID:20852044 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IMP RGD PMID:18759855 RGD:2308879 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cd38 CD38 molecule IMP RGD PMID:21431168 RGD:13506923 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Edn1 endothelin 1 involved_in IDA
ISO		 (PMID:8982507) RGD PMID:8982507 PMID:7586220 RGD:8662314 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 involved_in ISO
IEA		 (PMID:8982507)
GO_REF:0000107		 RGD
Ensembl		 PMID:8982507 GO_REF:0000107 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Edn3 endothelin 3 NOT|involved_in ISO (PMID:8982507) RGD PMID:8982507 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO
IEA		 (PMID:8982507)
GO_REF:0000107		 RGD
Ensembl		 PMID:8982507 GO_REF:0000107 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Grip2 glutamate receptor interacting protein 2 acts_upstream_of_or_within ISO MGI:3035933 (PMID:23117660) RGD PMID:23117660 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:14752059 RGD:7257678 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Mkks MKKS centrosomal shuttling protein acts_upstream_of_or_within ISO MGI:3526444 (PMID:20852044) RGD PMID:20852044 NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179831 (PMID:19553501)		 Ensembl
RGD		 PMID:19553501 GO_REF:0000107 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:19088082 RGD:10042965 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
esophagus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sulf1 sulfatase 1 involved_in IEA
ISO
ISS		 GO_REF:0000104
UniProtKB:Q8CFG0 (MGI:3722747|PMID:17720696)
GO_REF:0000024		 UniProt
RGD		 PMID:17720696 GO_REF:0000024 GO_REF:0000104 MGI:3722747 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Sulf2 sulfatase 2 involved_in ISO UniProtKB:Q8K007 (MGI:3722747|PMID:17720696) RGD PMID:17720696 MGI:3722747 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1d 5-hydroxytryptamine receptor 1D involved_in ISO (PMID:9186750) RGD PMID:9186750 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:7599919), (PMID:9186750)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:7599919 PMID:9186750 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:24170253 GO_REF:0000033, RGD:10043193 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Tacr2 tachykinin receptor 2 IMP RGD PMID:11275010 RGD:5147481 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
negative regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IMP RGD PMID:23647678 RGD:10412032 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11991626 RGD:10003093 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18306009 RGD:5129131 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:88398|MGI:98496 (PMID:12925702)		 Ensembl
RGD		 PMID:12925702 GO_REF:0000107 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Calca calcitonin-related polypeptide alpha acts_upstream_of_or_within IMP
ISO		 (PMID:9322931) RGD PMID:9322931 PMID:11230364 RGD:68890 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calcrl calcitonin receptor like receptor IMP RGD PMID:17363466 RGD:1625357 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO MGI:3525059 (PMID:15483626) RGD PMID:15483626 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:1934143 (PMID:17993584) RGD PMID:17993584 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within ISO MGI:2181586 (PMID:15483626) RGD PMID:15483626 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21051526 RGD:5135055 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
negative regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:17664026 RGD:6893570 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adra2c adrenoceptor alpha 2C IMP RGD PMID:17664026 RGD:6893570 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
negative regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap42 Rho GTPase activating protein 42 acts_upstream_of_or_within ISO MGI:3871380 (PMID:24335996) RGD PMID:24335996 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Dock4 dedicator of cytokinesis 4 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855 		JBrowse link
G Dock5 dedicator of cytokinesis 5 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IMP PMID:19237536 UniProt PMID:19237536 RGD:401901238 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
peristalsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2183545 (PMID:9788961) RGD PMID:9788961 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3699270 (PMID:17172448)		 Ensembl
RGD		 PMID:17172448 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:94924 (PMID:15272078)		 Ensembl
RGD		 PMID:15272078 GO_REF:0000107 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:2388386|MGI:99578 (PMID:15272078), (PMID:16525059) RGD PMID:15272078 PMID:16525059 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
MGI:2136846 (PMID:11774071)
(MGI:81287|PMID:8657307)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8657307 PMID:11774071 GO_REF:0000024 GO_REF:0000107 MGI:81287 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:12919938 RGD:1642317 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G P2rx2 purinergic receptor P2X 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2687349 (PMID:12937291)		 Ensembl
RGD		 PMID:12937291 GO_REF:0000107 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891 		JBrowse link
G P2rx3 purinergic receptor P2X 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934019 (PMID:12813150)		 Ensembl
RGD		 PMID:12813150 GO_REF:0000107 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178 		JBrowse link
G Sstr2 somatostatin receptor 2 IMP RGD PMID:12504886 RGD:727490 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351 		JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:17322067 RGD:12910822 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:24170253 RGD:10043193 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:15890336 RGD:12907565 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:10821044 RGD:10043148 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Spx spexin hormone involved_in ISO
IBA
ISS		 (PMID:17284679)
GO_REF:0000033		 RGD
GO_Central		 PMID:17284679 PMID:17284679 GO_REF:0000033, RGD:12907558 NCBI chr 4:175,356,044...175,362,082
Ensembl chr 4:175,356,247...175,362,082 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19258489 RGD:2304084 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IDA RGD PMID:14724155 RGD:9835340 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:9832052 RGD:12910753 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:15890336 PMID:21874246 RGD:12907565, RGD:12910732 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:21874246 PMID:15890336 RGD:12910732, RGD:12907565 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:7542218 RGD:12910748 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:18340377)		 Ensembl
RGD		 PMID:18340377 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP
IEA
ISO		 GO_REF:0000107
(MGI:4947862|PMID:21335239)		 Ensembl
RGD		 PMID:21335239 PMID:19041301 GO_REF:0000107 MGI:4947862, RGD:5688345 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 acts_upstream_of_or_within ISO (PMID:12925702) RGD PMID:12925702 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Cttn cortactin involved_in ISO
IEA		 UniProtKB:P07737 (PMID:24700464)
GO_REF:0000107		 RGD
Ensembl		 PMID:24700464 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within IDA
ISO
IMP		 (PMID:8010105) RGD PMID:8010105 PMID:12396026 PMID:8893723 RGD:1581797, RGD:8662282 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA		 (PMID:2768235)
GO_REF:0000107		 RGD
Ensembl		 PMID:2768235 PMID:12396026 GO_REF:0000107, RGD:1581797 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G F2r coagulation factor II (thrombin) receptor IDA RGD PMID:14699501 RGD:1582292 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G Itga2 integrin subunit alpha 2 IMP SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Myocd myocardin involved_in ISO
IEA		 (PMID:17215356)
GO_REF:0000107		 RGD
Ensembl		 PMID:17215356 GO_REF:0000107 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nmu neuromedin U involved_in IMP
IBA
IDA		 GO_REF:0000033
PMID:3178840		 GO_Central
RGD		 PMID:16474416 PMID:3178840 GO_REF:0000033, RGD:1642122, RGD:13461757 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Npnt nephronectin involved_in ISO (MGI:4947862|PMID:21335239) RGD PMID:21335239 MGI:4947862 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Prok2 prokineticin 2 involved_in ISO (PMID:11259612) RGD PMID:11259612 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385 		JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:10821044 RGD:10043148 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:18480553 RGD:2300247 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18480553 RGD:2300247 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17379756 RGD:1642962 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA		 (PMID:12847068)
GO_REF:0000107		 RGD
Ensembl		 PMID:12847068 GO_REF:0000107 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Srf serum response factor involved_in ISO (PMID:17215356) RGD PMID:17215356 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Tbxa2r thromboxane A2 receptor acts_upstream_of_or_within ISO (PMID:12925702) RGD PMID:12925702 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176 		JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:18562635 RGD:10043314 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Adra2b adrenoceptor alpha 2B IMP RGD PMID:19634638 PMID:17664026 RGD:2313546, RGD:6893570 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA
ISS		 (PMID:21427217)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21427217 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase IMP RGD PMID:19208792 RGD:2316554 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19164477 RGD:2303954 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:19164477 RGD:2303954 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Tacr1 tachykinin receptor 1 IDA RGD PMID:12390879 RGD:2305937 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tacr2 tachykinin receptor 2 IDA RGD PMID:12390879 RGD:2305937 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:12390879 RGD:2305937 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:8428203 RGD:2303387 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (PMID:24335996) RGD PMID:24335996 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:16873401 RGD:1625276 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within ISO MGI:2451291 (PMID:14627611) RGD PMID:14627611 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Cav1 caveolin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180364 (PMID:16782699), (PMID:17098833)		 Ensembl
RGD		 PMID:16782699 PMID:17098833 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12185001 GO_REF:0000033, RGD:724728 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit acts_upstream_of_or_within ISO MGI:2155602 (PMID:10318955), (PMID:10771006) RGD PMID:10318955 PMID:10771006 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit acts_upstream_of_or_within ISO MGI:2158716 (PMID:10771006) RGD PMID:10771006 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IDA RGD PMID:12062723 RGD:1582498 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Nmu neuromedin U involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:28275141)		 Ensembl
RGD		 PMID:28275141 GO_REF:0000107 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (PMID:10638758), (PMID:11570704) RGD PMID:10638758 PMID:11570704 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G Shc1 SHC adaptor protein 1 IMP RGD PMID:27270176 RGD:12792230 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Tnni3 troponin I3, cardiac type IMP RGD PMID:16236710 RGD:1580418 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Setd3 SET domain containing 3, actin N3(tau)-histidine methyltransferase involved_in ISS
ISO		 GO_REF:0000024
(MGI:6276231|PMID:30626964)		 UniProt
RGD		 PMID:30626964 GO_REF:0000024 MGI:6276231 NCBI chr 6:127,023,058...127,090,020
Ensembl chr 6:127,023,058...127,090,008 		JBrowse link
G Tacr1 tachykinin receptor 1 involved_in ISO (MGI:5619483|PMID:15647454) RGD PMID:15647454 MGI:5619483 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tacr2 tachykinin receptor 2 involved_in ISO (MGI:5619483|PMID:15647454) RGD PMID:15647454 MGI:5619483 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2b adrenoceptor alpha 2B IMP RGD PMID:18054907 RGD:2313547 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6282934|PMID:24805951)		 UniProt
Ensembl
RGD		 PMID:24805951 GO_REF:0000024 GO_REF:0000107 MGI:6282934 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IMP inhibition decreases both calcium-stimulated and unstimulated myogenic tone in middle cerebral arteries (p<0.001) RGD PMID:10198244 RGD:2293329 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (PMID:16920810) RGD PMID:16920810 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 involved_in ISO (MGI:5921050|PMID:26715683) RGD PMID:26715683 MGI:5921050 NCBI chr 5:97,227,621...97,286,866
Ensembl chr 5:97,229,345...97,286,537 		JBrowse link
regulation of vein smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 enables IDA salbutamol, isoproterenol, clenbuterol, norepinephrine RGD PMID:6289140 RGD:2301944 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:31125290 RGD:14696717 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
relaxation of vascular associated smooth muscle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor acts_upstream_of_or_within ISO MGI:3773754 (PMID:18340377) RGD PMID:18340377 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 acts_upstream_of_or_within ISO MGI:3640802 (PMID:16614755) RGD PMID:16614755 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO MGI:3525059 (PMID:15483626) RGD PMID:15483626 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:25139746)
MGI:3050114 (PMID:15867178)		 RGD PMID:15867178 PMID:25139746 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within ISO MGI:2181586 (PMID:15483626) RGD PMID:15483626 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:2682081|PMID:14608379) RGD PMID:14608379 MGI:2682081 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857873 (PMID:12433839), (PMID:14679182)		 UniProt
RGD		 PMID:12433839 PMID:14679182 GO_REF:0000024 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:25139746) RGD PMID:25139746 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn11a sodium voltage-gated channel alpha subunit 11 involved_in IEA
ISO		 GO_REF:0000107
MGI:5558025 (PMID:32817686)		 Ensembl
RGD		 PMID:32817686 GO_REF:0000107 NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044 		JBrowse link
smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C acts_upstream_of_or_within ISO MGI:2674119 (PMID:15132976) RGD PMID:15132976 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11641143)
MGI:3053849 (PMID:15827347)
GO_REF:0000107		 RGD
Ensembl		 PMID:11641143 PMID:15827347 GO_REF:0000107 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:18945947 RGD:2304258 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 acts_upstream_of_or_within ISO MGI:1934023 (PMID:12161756) RGD PMID:12161756 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
smooth muscle relaxation of the bladder outlet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) RGD PMID:23846981 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Pgr progesterone receptor involved_in ISO (PMID:24296318) RGD PMID:24296318 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
tonic smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk myosin light chain kinase involved_in ISO
IBA		 (MGI:4452414|PMID:20018858)
GO_REF:0000033		 RGD
GO_Central		 PMID:20018858 GO_REF:0000033 MGI:4452414 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
ureteric peristalsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx2 T-box transcription factor 2 acts_upstream_of_or_within ISO MGI:98495 (PMID:30478225) RGD PMID:30478225 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:98494 (PMID:30478225) RGD PMID:30478225 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tshz3 teashirt zinc finger homeobox 3 involved_in ISO (MGI:3806378|PMID:18776146) RGD PMID:18776146 MGI:3806378 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874 		JBrowse link
urinary bladder smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3703409|PMID:16956963)		 UniProt
RGD		 PMID:16956963 GO_REF:0000024 MGI:3703409 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Bdkrb2 bradykinin receptor B2 involved_in ISO (PMID:23846981) RGD PMID:23846981 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:23274492 RGD:7257664 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:20969855 RGD:6480667 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G P2rx2 purinergic receptor P2X 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1097160|MGI:2687349 (PMID:15961431)		 Ensembl
RGD		 PMID:15961431 GO_REF:0000107 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891 		JBrowse link
G P2rx3 purinergic receptor P2X 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934019|MGI:2665170 (PMID:11069181), (PMID:15961431)		 Ensembl
RGD		 PMID:11069181 PMID:15961431 GO_REF:0000107 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178 		JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:12750876 RGD:6482755 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:18562635 RGD:10043314 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP RGD PMID:21367919 RGD:10043365 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 acts_upstream_of_or_within ISO MGI:1934023 (PMID:12161756) RGD PMID:12161756 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21401609 RGD:5129172 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin, alpha 1, skeletal muscle involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acta2 actin alpha 2, smooth muscle involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3665248 (PMID:11053242)		 Ensembl
RGD		 PMID:11053242 GO_REF:0000107 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actg2 actin gamma 2, smooth muscle involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180787 (PMID:27498005)		 Ensembl
RGD		 PMID:27498005 GO_REF:0000107 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 IMP RGD PMID:18348285 RGD:2314690 NCBI chr 2:227,500,366...227,645,213
Ensembl chr 2:227,500,367...227,645,169 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (MGI:1927695|PMID:10967099) RGD PMID:10967099 MGI:1927695 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
vein smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 involved_in ISO
IBA		 (PMID:9422810)
GO_REF:0000033		 RGD
GO_Central		 PMID:9422810 GO_REF:0000033 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 involved_in ISO
IBA
IEA		 (PMID:8982507), (PMID:9422810)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8982507 PMID:9422810 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Edn3 endothelin 3 involved_in ISO
IBA		 (PMID:8982507)
GO_REF:0000033		 RGD
GO_Central		 PMID:8982507 GO_REF:0000033 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO (PMID:8982507) RGD PMID:8982507 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    multicellular organismal process 8852
      system process 3531
        muscle system process 486
          muscle contraction 345
            smooth muscle contraction 128
              colon smooth muscle contraction + 2
              gastro-intestinal system smooth muscle contraction + 15
              hindgut contraction + 3
              negative regulation of smooth muscle contraction + 24
              phasic smooth muscle contraction + 30
              positive regulation of smooth muscle contraction + 36
              regulation of smooth muscle contraction + 74
              small intestine smooth muscle contraction + 6
              tonic smooth muscle contraction + 15
              urinary tract smooth muscle contraction + 16
              uterine smooth muscle contraction + 13
              vascular associated smooth muscle contraction + 35
paths to the root