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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of muscle contraction
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Accession:GO:0006937 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of muscle contraction.


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regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G ADRA1B adrenoceptor alpha 1B involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:155,307,148...155,363,785
Ensembl chr 5:161,923,895...161,979,461 		JBrowse link
G ANXA6 annexin A6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2177904|PMID:11919174) Ensembl
MGI		 PMID:11919174 GO_REF:0000107 MGI:2177904 NCBI chr 5:146,528,446...146,585,186
Ensembl chr 5:152,530,445...152,652,231 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1337471|PMID:10360172) Ensembl
MGI		 PMID:10360172 GO_REF:0000107 MGI:1337471 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G CCDC69 coiled-coil domain containing 69 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:146,608,461...146,651,876
Ensembl chr 5:152,530,445...152,652,231 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit acts_upstream_of_or_within ISO (MGI:1336857|PMID:10318955) MGI PMID:10318955 MGI:1336857 NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044 		JBrowse link
G KCNA1 potassium voltage-gated channel subfamily A member 1 involved_in ISO PMID:22206926 UniProt PMID:22206926 RGD:10047237 NCBI chr12:5,027,333...5,037,136
Ensembl chr12:4,950,938...4,952,425 		JBrowse link
G PRKCA protein kinase C alpha acts_upstream_of_or_within ISO (MGI:3033566|PMID:14966518) MGI PMID:14966518 MGI:3033566 NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903 		JBrowse link
G TNNC1 troponin C1, slow skeletal and cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,393,106...52,396,076
Ensembl chr 3:53,621,749...53,624,726 		JBrowse link
G TNNC2 troponin C2, fast skeletal type involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,162,502...42,172,829
Ensembl chr20:43,249,725...43,254,134 		JBrowse link
G TNNI3 troponin I3, cardiac type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2653723|PMID:12551921) Ensembl
MGI		 PMID:12551921 GO_REF:0000107 MGI:2653723 NCBI chr19:52,193,061...52,198,782
Ensembl chr19:60,887,630...60,894,219 		JBrowse link
G TNNT1 troponin T1, slow skeletal type involved_in IEA InterPro GO_REF:0000002 NCBI chr19:52,173,523...52,190,577
Ensembl chr19:60,868,330...60,882,005 		JBrowse link
G TNNT2 troponin T2, cardiac type involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:176,957,298...176,976,033 JBrowse link
G TNNT3 troponin T3, fast skeletal type involved_in IEA InterPro GO_REF:0000002 NCBI chr11:1,936,614...1,955,784
Ensembl chr11:1,968,184...1,987,849 		JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31754830 RGD:329403060 NCBI chr 1:143,239,576...143,404,038
Ensembl chr 1:147,023,671...147,129,705 		JBrowse link
negative regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE5A phosphodiesterase 5A involved_in ISO (MGI:3836877|PMID:19127022) BHF-UCL PMID:19127022 MGI:3836877 NCBI chr 4:111,682,772...111,817,234
Ensembl chr 4:122,832,175...122,966,636 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
negative regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNNT1 troponin T1, slow skeletal type involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,173,523...52,190,577
Ensembl chr19:60,868,330...60,882,005 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBN1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872 		JBrowse link
negative regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO RGD PMID:23647678 RGD:10412032 NCBI chr10:73,391,297...74,158,488
Ensembl chr10:76,062,047...76,820,644 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11991626 RGD:10003093 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148 		JBrowse link
negative regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:18306009 RGD:5129131 NCBI chr10:110,642,491...110,646,595 JBrowse link
G ADRB2 adrenoceptor beta 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2672939|PMID:12925702) MGI
Ensembl		 PMID:12925702 GO_REF:0000107 MGI:2672939 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892 		JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:1098356|PMID:9322931) RGD
Ensembl
MGI		 PMID:9322931 PMID:11230364 GO_REF:0000107 MGI:1098356 RGD:68890 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267 		JBrowse link
G CALCRL calcitonin receptor like receptor ISO RGD PMID:17363466 RGD:1625357 NCBI chr2B:74,622,892...74,728,067
Ensembl chr2B:192,422,283...192,463,064 		JBrowse link
G IRAG1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO (MGI:3512693|PMID:15483626) MGI PMID:15483626 MGI:3512693 NCBI chr11:10,708,215...10,828,102
Ensembl chr11:10,435,670...10,495,012 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (MGI:3771783|PMID:17993584) MGI PMID:17993584 MGI:3771783 Ensembl chr 7:81,917,167...81,932,589 JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3512693|PMID:15483626) MGI
Ensembl		 PMID:15483626 GO_REF:0000107 MGI:3512693 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21051526 RGD:5135055 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
negative regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 ISO RGD PMID:16537391 RGD:1582129 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3688972|PMID:11507009) MGI
Ensembl		 PMID:11507009 GO_REF:0000107 MGI:3688972 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO (PMID:10914677) UniProt PMID:10914677 Ensembl chr16:29,265,516...29,290,807
Ensembl chr16:29,265,516...29,290,807 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066 		JBrowse link
negative regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2A adrenoceptor alpha 2A ISO RGD PMID:17664026 RGD:6893570 NCBI chr10:107,669,860...107,673,685 JBrowse link
G ADRA2C adrenoceptor alpha 2C ISO RGD PMID:17664026 RGD:6893570 NCBI chr 4:3,904,346...3,906,577 JBrowse link
negative regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP42 Rho GTPase activating protein 42 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5638847|PMID:24335996) MGI
Ensembl		 PMID:24335996 GO_REF:0000107 MGI:5638847 NCBI chr11:95,655,874...95,962,003
Ensembl chr11:99,159,634...99,460,060 		JBrowse link
G DOCK4 dedicator of cytokinesis 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:103,697,418...104,169,469
Ensembl chr 7:116,400,535...116,871,755 		JBrowse link
G DOCK5 dedicator of cytokinesis 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:24,463,582...24,696,736
Ensembl chr 8:21,372,756...21,605,877 		JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378 		JBrowse link
neurotransmitter secretion involved in regulation of skeletal muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A1 nuclear receptor subfamily 4 group A member 1 ISO RGD PMID:29530712 RGD:40924655 NCBI chr12:36,703,903...36,740,211
Ensembl chr12:37,480,300...37,501,188 		JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23954346 RGD:10003031 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464 		JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO RGD PMID:19443576 RGD:7205486 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in ISO (MGI:6304509|PMID:30299255) UniProt PMID:30299255 MGI:6304509 NCBI chr 3:152,346,768...152,351,244
Ensembl chr 3:160,399,367...160,402,051 		JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G CCN2 cellular communication network factor 2 ISO RGD PMID:19707545 RGD:2314476 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CHGA chromogranin A involved_in ISO PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr14:73,555,834...73,568,547
Ensembl chr14:92,895,450...92,908,159 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:21620734 RGD:5686387 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO (PMID:19646991) BHF-UCL PMID:19646991 NCBI chr11:2,469,750...2,874,467 JBrowse link
G NPPA natriuretic peptide A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955 		JBrowse link
G SMTN smoothelin acts_upstream_of_or_within ISO (MGI:4437553|PMID:18678771) MGI PMID:18678771 MGI:4437553 NCBI chr22:12,105,016...12,128,365
Ensembl chr22:29,942,895...29,966,256 		JBrowse link
G UCN urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669 		JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:17322067 RGD:12910822 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:24170253 RGD:10043193 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063 		JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,265,516...29,290,807
Ensembl chr16:29,265,516...29,290,807 		JBrowse link
G MYLK2 myosin light chain kinase 2 ISO RGD PMID:12748068 RGD:1580242 NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508 		JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 RGD:12907565 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G SPX spexin hormone involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,766,136...64,771,728
Ensembl chr12:67,369,413...67,375,630 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19258489 RGD:2304084 NCBI chr20:3,157,246...3,159,013 JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:14724155 RGD:9835340 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796 		JBrowse link
positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:9832052 RGD:12910753 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:7542218 RGD:12910748 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3794903|PMID:18340377) MGI
Ensembl		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in ISO
IEA		 RGD
Ensembl		 PMID:19041301 GO_REF:0000107 RGD:5688345 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 acts_upstream_of_or_within ISO (MGI:2672939|PMID:12925702) MGI PMID:12925702 MGI:2672939 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857 		JBrowse link
G EDN1 endothelin 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:66444|PMID:8010105) RGD
Ensembl
MGI		 PMID:8010105 PMID:8893723 PMID:12396026 GO_REF:0000107 MGI:66444 RGD:1581797 RGD:8662282 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545 		JBrowse link
G EDN2 endothelin 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:65983|PMID:2768235) RGD
Ensembl
MGI		 PMID:2768235 PMID:12396026 GO_REF:0000107 MGI:65983 RGD:1581797 NCBI chr 1:40,777,582...40,783,410
Ensembl chr 1:42,092,811...42,098,721 		JBrowse link
G ITGA2 integrin subunit alpha 2 ISO SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
G MYOCD myocardin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659 		JBrowse link
G NMU neuromedin U involved_in ISO PMID:3178840 RGD
UniProt		 PMID:3178840 PMID:16474416 RGD:13461757 RGD:1642122 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
G NPNT nephronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,365,727...98,445,746
Ensembl chr 4:108,974,971...109,054,671 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231 		JBrowse link
G PROK2 prokineticin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:71,711,334...71,724,865
Ensembl chr 3:73,068,599...73,080,897 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:10821044 RGD:10043148 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17379756 RGD:1642962 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
G SRF serum response factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768 		JBrowse link
G TBXA2R thromboxane A2 receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2672939|PMID:12925702) MGI
Ensembl		 PMID:12925702 GO_REF:0000107 MGI:2672939 NCBI chr19:2,621,606...2,632,800
Ensembl chr19:3,570,290...3,581,924 		JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:18562635 RGD:10043314 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063 		JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NMU neuromedin U involved_in ISO PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3688972|PMID:11507009) MGI
Ensembl		 PMID:11507009 GO_REF:0000107 MGI:3688972 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO RGD PMID:32706268 RGD:38549369 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO RGD PMID:17664026 PMID:19634638 RGD:2313546 RGD:6893570 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:21427217) UniProt PMID:21427217 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO RGD PMID:19208792 RGD:2316554 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19164477 RGD:2303954 NCBI chr20:3,157,246...3,159,013 JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:19164477 RGD:2303954 NCBI chr 3:8,701,344...8,721,706 JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:12390879 RGD:2305937 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018 		JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12390879 RGD:2305937 NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224 		JBrowse link
G TACR3 tachykinin receptor 3 ISO RGD PMID:12390879 RGD:2305937 NCBI chr 4:96,022,788...96,162,249
Ensembl chr 4:106,644,943...106,776,172 		JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:8428203 RGD:2303387 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G RHOA ras homolog family member A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5638847|PMID:24335996) MGI
Ensembl		 PMID:24335996 GO_REF:0000107 MGI:5638847 NCBI chr 3:49,282,009...49,339,887 JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905 		JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413 		JBrowse link
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509 		JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:83,942,590...84,108,648
Ensembl chr 7:97,540,356...97,705,608 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in ISO PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923 		JBrowse link
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G FGF13 fibroblast growth factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:127,764,648...128,353,928
Ensembl chr  X:138,023,016...138,103,217 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,231,906...52,285,220
Ensembl chr15:70,997,020...71,042,285 		JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,369,556...43,371,025
Ensembl chr17:48,101,744...48,103,394 		JBrowse link
regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO RGD PMID:19525381 RGD:2317914 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19525381 PMID:22216755 RGD:2317914 RGD:6893639 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AKAP6 A-kinase anchoring protein 6 involved_in ISO PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr14:12,978,221...13,602,732
Ensembl chr14:31,395,026...31,792,166 		JBrowse link
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:15629895 RGD:6903236 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO RGD PMID:17442282 RGD:6903343 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G CASQ2 calsequestrin 2 involved_in ISO PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311 		JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 ISO RGD PMID:14684371 RGD:9685468 NCBI chr19:32,080,180...32,089,141
Ensembl chr19:40,824,448...40,827,039 		JBrowse link
G GATA4 GATA binding protein 4 ISO RGD PMID:21702924 RGD:7207043 NCBI chr 8:7,442,921...7,526,731 JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 ISO RGD PMID:22426100 RGD:7247430 NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129 		JBrowse link
G MYH7B myosin heavy chain 7B ISO RGD PMID:32207065 RGD:126925946 NCBI chr20:31,284,197...31,330,893
Ensembl chr20:32,428,870...32,455,569 		JBrowse link
G PDE4B phosphodiesterase 4B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:65,038,120...65,620,764
Ensembl chr 1:67,045,911...67,506,291 		JBrowse link
G PDE4D phosphodiesterase 4D involved_in ISO (MGI:5286798|PMID:21670503), (MGI:5442270|PMID:21903937)
PMID:19801680		 RGD
BHF-UCL		 PMID:19801680 PMID:21670503 PMID:21903937 MGI:5286798 MGI:5442270 RGD:7327160 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111 		JBrowse link
G PLN phospholamban acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3655311|PMID:8620604) MGI
Ensembl		 PMID:8620604 GO_REF:0000107 MGI:3655311 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695100|PMID:16172272) MGI
Ensembl		 PMID:16172272 GO_REF:0000107 MGI:3695100 NCBI chr 3:38,444,421...38,546,364
Ensembl chr 3:38,728,897...38,812,202 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029 		JBrowse link
G STC1 stanniocalcin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:23,089,339...23,102,245
Ensembl chr 8:20,023,469...20,036,321 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (MGI:5292424|PMID:21900893) BHF-UCL PMID:21900893 MGI:5292424 NCBI chr2B:89,461,773...89,493,879
Ensembl chr2B:207,613,654...207,645,590 		JBrowse link
regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO RGD PMID:20334814 RGD:2317910 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G ADRA1A adrenoceptor alpha 1A involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G ADRA1B adrenoceptor alpha 1B involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:155,307,148...155,363,785
Ensembl chr 5:161,923,895...161,979,461 		JBrowse link
G AGRN agrin involved_in ISO (MGI:4352602|PMID:19376779) BHF-UCL PMID:19376779 MGI:4352602 Ensembl chr 1:936,000...966,808 JBrowse link
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905 		JBrowse link
G BMP10 bone morphogenetic protein 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:68,901,944...68,912,559
Ensembl chr2A:70,023,655...70,034,420 		JBrowse link
G CALM1 calmodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135 		JBrowse link
G CALM2 calmodulin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697 		JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135 		JBrowse link
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G EHD3 EH domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:31,245,908...31,280,485
Ensembl chr2A:31,317,432...31,353,312 		JBrowse link
G GJA5 gap junction protein alpha 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413 		JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,231,906...52,285,220
Ensembl chr15:70,997,020...71,042,285 		JBrowse link
G LOC100990811 fucose-1-phosphate guanylyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:73,464,364...73,772,977
Ensembl chr 1:75,403,555...75,747,240 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514 		JBrowse link
G P2RX4 purinergic receptor P2X 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:118,807,961...118,832,267
Ensembl chr12:122,178,672...122,202,959 		JBrowse link
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,593,765...38,691,172
Ensembl chr 3:38,876,068...38,972,247 		JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (MGI:3836072|PMID:18952608) BHF-UCL PMID:18952608 MGI:3836072 NCBI chr18:42,306,324...42,337,214 JBrowse link
regulation of cardiac muscle contraction by calcium ion signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:144,592,667...144,621,052
Ensembl chr 1:148,314,793...148,342,050 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in ISO (PMID:10587333)
PMID:9851937		 BHF-UCL PMID:9851937 PMID:10587333 RGD:10047146 NCBI chr12:107,857,009...107,924,938
Ensembl chr12:111,246,508...111,311,923 		JBrowse link
G HDAC4 histone deacetylase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3793386|PMID:18250163) MGI
Ensembl		 PMID:18250163 GO_REF:0000107 MGI:3793386 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054 		JBrowse link
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,359,818...26,418,910
Ensembl chr 1:27,414,937...27,475,089 		JBrowse link
G TNNI3 troponin I3, cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,193,061...52,198,782
Ensembl chr19:60,887,630...60,894,219 		JBrowse link
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK2 ankyrin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:105,315,776...105,882,506
Ensembl chr 4:115,967,106...116,443,905 		JBrowse link
G CASQ2 calsequestrin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202079|PMID:9525981) MGI
Ensembl		 PMID:9525981 GO_REF:0000107 MGI:1202079 NCBI chr 1:86,795,392...86,864,196
Ensembl chr 1:121,844,097...121,913,311 		JBrowse link
G DMD dystrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082 		JBrowse link
G PLN phospholamban acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:82999|PMID:8831698) MGI
Ensembl		 PMID:8831698 GO_REF:0000107 MGI:82999 NCBI chr 6:116,357,335...116,370,382
Ensembl chr 6:120,509,510...120,509,668 		JBrowse link
G RYR2 ryanodine receptor 2 involved_in ISO (MGI:3621834|PMID:12837242) BHF-UCL PMID:12837242 MGI:3621834 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in ISO PMID:21779914 BHF-UCL PMID:21779914 RGD:8554732 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038 		JBrowse link
G TMEM38A transmembrane protein 38A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3715564|PMID:17611541) MGI
Ensembl		 PMID:17611541 GO_REF:0000107 MGI:3715564 NCBI chr19:16,150,715...16,179,256
Ensembl chr19:17,129,842...17,159,002 		JBrowse link
G TMEM38B transmembrane protein 38B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3715564|PMID:17611541) MGI
Ensembl		 PMID:17611541 GO_REF:0000107 MGI:3715564 NCBI chr 9:76,854,177...76,938,334
Ensembl chr 9:104,980,935...105,128,988 		JBrowse link
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMPK DM1 protein kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3721737|PMID:11526199) MGI
Ensembl		 PMID:11526199 GO_REF:0000107 MGI:3721737 NCBI chr19:42,779,173...42,791,981
Ensembl chr19:51,316,099...51,329,355 		JBrowse link
regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHSR growth hormone secretagogue receptor ISO RGD PMID:16873401 RGD:1625276 NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202 		JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYLK2 myosin light chain kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:28,113,024...28,128,142
Ensembl chr20:29,243,391...29,258,508 		JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNNC1 troponin C1, slow skeletal and cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,393,106...52,396,076
Ensembl chr 3:53,621,749...53,624,726 		JBrowse link
G TNNT2 troponin T2, cardiac type involved_in ISO PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr 1:176,957,298...176,976,033 JBrowse link
regulation of skeletal muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C12H12orf57 chromosome 12 C12orf57 homolog involved_in ISO (PMID:23453665), (PMID:23633300), (PMID:24798461) UniProt PMID:23453665 PMID:23633300 PMID:24798461 NCBI chr12:7,073,251...7,075,408
Ensembl chr12:6,978,576...6,990,580 		JBrowse link
G CAV3 caveolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G DMD dystrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733 		JBrowse link
G SLC8A3 solute carrier family 8 member A3 involved_in ISO (MGI:3027331|PMID:14722618) UniProt PMID:14722618 MGI:3027331 NCBI chr14:50,634,091...50,779,712 JBrowse link
regulation of skeletal muscle contraction by action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCN4A sodium voltage-gated channel alpha subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,034,146...58,066,644
Ensembl chr17:63,128,550...63,161,043 		JBrowse link
regulation of skeletal muscle contraction by calcium ion signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMPK DM1 protein kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:42,779,173...42,791,981
Ensembl chr19:51,316,099...51,329,355 		JBrowse link
G REM1 RRAD and GEM like GTPase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6708323|PMID:26078055) MGI
Ensembl		 PMID:26078055 GO_REF:0000107 MGI:6708323 NCBI chr20:27,764,390...27,774,026
Ensembl chr20:28,402,181...28,415,090 		JBrowse link
regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKD1 protein kinase D1 ISO RGD PMID:21041300 RGD:243065274 NCBI chr14:10,353,284...10,707,841
Ensembl chr14:28,496,282...28,650,030 		JBrowse link
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASQ1 calsequestrin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3814667|PMID:17627988) MGI
Ensembl		 PMID:17627988 GO_REF:0000107 MGI:3814667 NCBI chr 1:135,544,249...135,555,545
Ensembl chr 1:139,465,605...139,476,969 		JBrowse link
G DMD dystrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733 		JBrowse link
regulation of skeletal muscle contraction via regulation of action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:64,097,908...64,112,914
Ensembl chr17:69,487,846...69,489,129 		JBrowse link
regulation of slow-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100978529 myosin-7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:4,231,344...4,254,295
Ensembl chr14:22,325,812...22,348,763 		JBrowse link
G STRIT1 small transmembrane regulator of ion transport 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:152,346,768...152,351,244
Ensembl chr 3:160,399,367...160,402,051 		JBrowse link
regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2B adrenoceptor alpha 2B involved_in IEA InterPro GO_REF:0000002 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472 		JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3525892|PMID:14627611) MGI
Ensembl		 PMID:14627611 GO_REF:0000107 MGI:3525892 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G CAV1 caveolin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695200|PMID:16782699), (MGI:3707284|PMID:17098833) MGI
Ensembl		 PMID:16782699 PMID:17098833 GO_REF:0000107 MGI:3695200 MGI:3707284 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO RGD PMID:12185001 RGD:724728 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit acts_upstream_of_or_within ISO (MGI:1336857|PMID:10318955), (MGI:3607823|PMID:10771006) MGI PMID:10318955 PMID:10771006 MGI:1336857 MGI:3607823 NCBI chr15:57,523,553...57,550,228
Ensembl chr15:76,487,710...76,512,044 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit acts_upstream_of_or_within ISO (MGI:3607823|PMID:10771006) MGI PMID:10771006 MGI:3607823 NCBI chr15:57,552,697...57,570,828
Ensembl chr15:76,515,455...76,532,712 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:12062723 RGD:1582498 NCBI chr13:9,584,850...9,779,542 JBrowse link
G NMU neuromedin U involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (MGI:5926671|PMID:28275141) Ensembl
MGI		 PMID:28275141 GO_REF:0000107 MGI:5926671 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741 		JBrowse link
G P2RX1 purinergic receptor P2X 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1351403|PMID:10638758), (MGI:3607802|PMID:11570704) MGI
Ensembl		 PMID:10638758 PMID:11570704 GO_REF:0000107 MGI:1351403 MGI:3607802 NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:27270176 RGD:12792230 NCBI chr 1:130,310,778...130,323,001
Ensembl chr 1:133,920,532...133,929,008 		JBrowse link
G TNNI3 troponin I3, cardiac type ISO RGD PMID:16236710 RGD:1580418 NCBI chr19:52,193,061...52,198,782
Ensembl chr19:60,887,630...60,894,219 		JBrowse link
regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3577656|PMID:15253893) MGI
Ensembl		 PMID:15253893 GO_REF:0000107 MGI:3577656 NCBI chr 1:135,469,495...135,497,303
Ensembl chr 1:139,390,549...139,418,303 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO (PMID:9405806) UniProt PMID:9405806 Ensembl chr16:29,265,516...29,290,807
Ensembl chr16:29,265,516...29,290,807 		JBrowse link
G MYBPC3 myosin binding protein C3 involved_in ISO PMID:8799143 BHF-UCL PMID:8799143 RGD:8553425 NCBI chr11:47,277,799...47,299,102
Ensembl chr11:47,831,087...47,851,849 		JBrowse link
G MYL3 myosin light chain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:46,758,058...46,782,425
Ensembl chr 3:47,859,467...47,865,084 		JBrowse link
G TNNT3 troponin T3, fast skeletal type involved_in ISO
IEA		 RGD
Ensembl		 PMID:16839517 GO_REF:0000107 RGD:1599483 NCBI chr11:1,936,614...1,955,784
Ensembl chr11:1,968,184...1,987,849 		JBrowse link
regulation of the force of skeletal muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429 		JBrowse link
G KBTBD13 kelch repeat and BTB domain containing 13 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6460519|PMID:31671076)
(PMID:31671076)		 MGI
Ensembl		 PMID:31671076 GO_REF:0000107 MGI:6460519 NCBI chr15:44,016,331...44,019,797
Ensembl chr15:62,300,878...62,302,254 		JBrowse link
G LOC100978529 myosin-7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:4,231,344...4,254,295
Ensembl chr14:22,325,812...22,348,763 		JBrowse link
regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SETD3 SET domain containing 3, actin N3(tau)-histidine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:80,022,123...80,104,935
Ensembl chr14:99,343,164...99,426,486 		JBrowse link
G TACR1 tachykinin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018 		JBrowse link
G TACR2 tachykinin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224 		JBrowse link
regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2B adrenoceptor alpha 2B ISO RGD PMID:18054907 RGD:2313547 NCBI chr2A:103,198,432...103,202,506
Ensembl chr2A:97,040,126...97,041,472 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:87,107,900...87,229,514
Ensembl chr12:90,427,560...90,495,320 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO inhibition decreases both calcium-stimulated and unstimulated myogenic tone in middle cerebral arteries (p<0.001) RGD PMID:10198244 RGD:2293329 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G P2RX1 purinergic receptor P2X 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3694186|PMID:16920810) MGI
Ensembl		 PMID:16920810 GO_REF:0000107 MGI:3694186 NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595 		JBrowse link
G ZDHHC21 zinc finger DHHC-type palmitoyltransferase 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:14,430,035...14,528,888
Ensembl chr 9:14,969,373...15,037,554 		JBrowse link
regulation of vein smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 enables ISO salbutamol, isoproterenol, clenbuterol, norepinephrine RGD PMID:6289140 RGD:2301944 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:31125290 RGD:14696717 NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158 		JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CTNNA3 catenin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:62,388,454...64,177,116
Ensembl chr10:64,712,576...66,442,238 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987 		JBrowse link
G DSC2 desmocollin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:24,296,505...24,332,997
Ensembl chr18:27,894,603...27,930,843 		JBrowse link
G DSG2 desmoglein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:24,716,181...24,766,837
Ensembl chr18:28,313,223...28,363,786 		JBrowse link
G DSP desmoplakin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,381,046...7,426,408
Ensembl chr 6:7,664,211...7,709,391 		JBrowse link
G JUP junction plakoglobin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,527,115...15,559,251
Ensembl chr17:15,747,163...15,777,479 		JBrowse link
G PKP2 plakophilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,322,227...53,428,747
Ensembl chr12:55,925,174...56,030,998 		JBrowse link
G RYR2 ryanodine receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:212,600,198...213,387,312
Ensembl chr 1:217,815,676...218,383,509 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464 		JBrowse link
relaxation of vascular associated smooth muscle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3794903|PMID:18340377) Ensembl
MGI		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr17:34,849,466...34,880,088 JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3640061|PMID:16614755) Ensembl
MGI		 PMID:16614755 GO_REF:0000107 MGI:3640061 NCBI chr 4:148,032,167...148,102,757
Ensembl chr 4:159,850,107...159,913,338 		JBrowse link
G IRAG1 inositol 1,4,5-triphosphate receptor associated 1 acts_upstream_of_or_within ISO (MGI:3512693|PMID:15483626) MGI PMID:15483626 MGI:3512693 NCBI chr11:10,708,215...10,828,102
Ensembl chr11:10,435,670...10,495,012 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within
involved_in		 ISO (MGI:3695011|PMID:15867178)
(PMID:25139746)		 MGI
AgBase		 PMID:15867178 PMID:25139746 MGI:3695011 NCBI chr10:73,391,297...74,158,488
Ensembl chr10:76,062,047...76,820,644 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3512693|PMID:15483626) Ensembl
MGI		 PMID:15483626 GO_REF:0000107 MGI:3512693 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
G RGS2 regulator of G protein signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955 		JBrowse link
G SOD1 superoxide dismutase 1 acts_upstream_of_or_within ISO (MGI:2682495|PMID:14679182), (MGI:3625573|PMID:12433839) MGI PMID:12433839 PMID:14679182 MGI:2682495 MGI:3625573 NCBI chr21:18,029,831...18,037,526 JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
smooth muscle relaxation of the bladder outlet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB1 bradykinin receptor B1 involved_in ISO (PMID:23846981) AgBase PMID:23846981 NCBI chr14:76,885,923...76,894,456 JBrowse link
G PGR progesterone receptor involved_in ISO (PMID:24296318) AgBase PMID:24296318 NCBI chr11:95,997,677...96,098,866 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15635
    multicellular organismal process 7279
      system process 2100
        muscle system process 443
          muscle contraction 310
            regulation of muscle contraction 166
              negative regulation of muscle contraction + 34
              positive regulation of muscle contraction + 50
              regulation of muscle filament sliding + 4
              regulation of smooth muscle contraction + 71
              regulation of striated muscle contraction + 92
Path 2
Term Annotations click to browse term
  biological_process 15635
    biological regulation 10774
      regulation of biological process 10474
        regulation of multicellular organismal process 3057
          regulation of system process 629
            regulation of muscle system process 270
              regulation of muscle contraction 166
                negative regulation of muscle contraction + 34
                positive regulation of muscle contraction + 50
                regulation of muscle filament sliding + 4
                regulation of smooth muscle contraction + 71
                regulation of striated muscle contraction + 92
paths to the root