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ONTOLOGY REPORT - ANNOTATIONS


Term:substrate-dependent cell migration, cell attachment to substrate
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Accession:GO:0006931 term browser browse the term
Definition:The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.
Synonyms:exact_synonym: substrate-bound cell migration, cell attachment to substrate


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substrate-dependent cell migration, cell attachment to substrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPB41L5 erythrocyte membrane protein band 4.1 like 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3821807|PMID:18794329) Ensembl
MGI
PMID:18794329 GO_REF:0000107 MGI:3821807 NCBI chr15:31,159,214...31,295,891
Ensembl chr15:31,159,217...31,295,896
JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A acts_upstream_of_or_within ISO (MGI:1347374|PMID:10551889) MGI PMID:10551889 MGI:1347374 NCBI chr 3:39,166,288...39,168,294
Ensembl chr 3:39,166,294...39,168,303
JBrowse link
positive regulation of substrate-dependent cell migration, cell attachment to substrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBLN1 fibulin 1 involved_in ISO (PMID:25834989) UniProt PMID:25834989 NCBI chr 5:3,839,498...3,927,178
Ensembl chr 5:3,839,501...3,927,183
JBrowse link
G FN1 fibronectin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G STK4 serine/threonine kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,387,594...47,475,705
Ensembl chr17:47,376,115...47,475,718
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    cellular process 15862
      cell adhesion 1274
        cell-substrate adhesion 370
          substrate-dependent cell migration, cell attachment to substrate 5
            negative regulation of substrate-dependent cell migration, cell attachment to substrate 0
            positive regulation of substrate-dependent cell migration, cell attachment to substrate 3
            regulation of substrate-dependent cell migration, cell attachment to substrate + 3
Path 2
Term Annotations click to browse term
  biological_process 16579
    cellular process 15862
      movement of cell or subcellular component 2110
        cell motility 1700
          cell migration 1525
            substrate-dependent cell migration 28
              substrate-dependent cell migration, cell attachment to substrate 5
                negative regulation of substrate-dependent cell migration, cell attachment to substrate 0
                positive regulation of substrate-dependent cell migration, cell attachment to substrate 3
                regulation of substrate-dependent cell migration, cell attachment to substrate + 3
paths to the root