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ONTOLOGY REPORT - ANNOTATIONS

Term:phagocytosis, recognition
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Accession:GO:0006910 term browser browse the term
Definition:The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment:Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms:exact_synonym: recognition of phagocytosed substance by phagocytic cell

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phagocytosis, recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3587138|PMID:16061696) MGI
Ensembl		 PMID:16061696 GO_REF:0000107 MGI:3587138 NCBI chrNW_004936810:791,823...838,303 JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within		 ISO (PMID:11567029)
(MGI:3027358|PMID:14707091)		 UniProt
MGI		 PMID:11567029 PMID:14707091 MGI:3027358 NCBI chrNW_004936902:436,224...446,435 JBrowse link
G Colec12 collectin subfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936550:169,084...350,209 JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2679188|PMID:9551950), (MGI:2679189|PMID:11911823)
(MGI:2664488|PMID:11911824)		 MGI
Ensembl		 PMID:9551950 PMID:11911823 PMID:11911824 GO_REF:0000107 MGI:2664488 MGI:2679188 MGI:2679189 NCBI chrNW_004936580:115,552...144,970 JBrowse link
G LOC101964702 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:9,247,749...9,313,230 JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2681272|PMID:12000961) MGI
Ensembl		 PMID:12000961 GO_REF:0000107 MGI:2681272 NCBI chrNW_004936483:14,868,171...14,880,552 JBrowse link
G Scarb1 scavenger receptor class B member 1 ISO RGD PMID:12016218 RGD:1304245 NCBI chrNW_004936558:530,828...555,098 JBrowse link
G Sirpa signal regulatory protein alpha acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chrNW_004936485:16,608,317...16,654,552 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:18,659,725...18,665,406 JBrowse link
G Tub TUB bipartite transcription factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4441109|PMID:19837063)
(MGI:4867371|PMID:20978472)		 MGI
Ensembl		 PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chrNW_004936528:9,829,889...9,912,645 JBrowse link
G Tulp1 TUB like protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4867371|PMID:20978472)
(MGI:4441109|PMID:19837063)		 MGI
Ensembl		 PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chrNW_004936476:23,744,707...23,757,002 JBrowse link
opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G LOC101967799 leukocyte surface antigen CD47 acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chrNW_004936645:1,363,406...1,408,624 JBrowse link
G Ptx3 pentraxin 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3037598|PMID:14726497) MGI
Ensembl		 PMID:14726497 GO_REF:0000107 MGI:3037598 NCBI chrNW_004936519:4,303,549...4,309,143 JBrowse link
G Sftpd surfactant protein D ISO RGD PMID:19017984 RGD:4143523 NCBI chrNW_004936716:60,754...73,010 JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2686801|PMID:14691481) MGI
Ensembl		 PMID:14691481 GO_REF:0000107 MGI:2686801 NCBI chrNW_004936477:22,087,450...22,093,677 JBrowse link
positive regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Colec10 collectin subfamily member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:27,416,471...27,449,206 JBrowse link
G Colec11 collectin subfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936532:1,757,288...1,776,053 JBrowse link
G Fcn3 ficolin 3 involved_in ISO (PMID:11907111) ComplexPortal PMID:11907111 NCBI chrNW_004936474:11,680,166...11,685,214 JBrowse link
G LOC101965964 ficolin-1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:2,421,092...2,428,240 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chrNW_004936578:2,804,460...2,857,731 JBrowse link
G Masp2 MBL associated serine protease 2 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chrNW_004936474:100,584...113,781 JBrowse link
G Myo18a myosin XVIIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:5,257,165...5,351,757 JBrowse link
G Pla2g5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chrNW_004936474:6,131,915...6,150,810 JBrowse link
recognition of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcn3 ficolin 3 involved_in ISO (PMID:15804047) UniProt PMID:15804047 NCBI chrNW_004936474:11,680,166...11,685,214 JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1855743|PMID:10811223)
(MGI:2682078|PMID:14645847)		 MGI
Ensembl		 PMID:10811223 PMID:14645847 GO_REF:0000107 MGI:1855743 MGI:2682078 NCBI chrNW_004936594:1,760,924...1,771,022 JBrowse link
G LOC101965964 ficolin-1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:2,421,092...2,428,240 JBrowse link
G Megf10 multiple EGF like domains 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4414741|PMID:19915564) MGI
Ensembl		 PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chrNW_004936504:634,167...753,438 JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4414741|PMID:19915564) MGI
Ensembl		 PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chrNW_004936580:6,030,426...6,052,330 JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:530,828...555,098 JBrowse link
regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpb complement component 4 binding protein beta involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chrNW_004936557:5,546,692...5,561,531 JBrowse link
G LOC101973539 C4b-binding protein alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936557:5,511,372...5,535,158 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14993
    cellular process 13989
      cell recognition 129
        phagocytosis, recognition 29
          opsonization + 15
          recognition of apoptotic cell 6
Path 2
Term Annotations click to browse term
  biological_process 14993
    localization 4752
      establishment of localization 4137
        transport 3974
          vesicle-mediated transport 1369
            endocytosis 498
              phagocytosis, recognition 29
                opsonization + 15
                recognition of apoptotic cell 6
paths to the root