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ONTOLOGY REPORT - ANNOTATIONS

Term:phagocytosis, recognition
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Accession:GO:0006910 term browser browse the term
Definition:The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment:Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms:exact_synonym: recognition of phagocytosed substance by phagocytic cell


show annotations for term's descendants           Sort by:
phagocytosis, recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO
IEA		 (MGI:4939876|PMID:21245295)
GO_REF:0000107		 RGD
Ensembl		 PMID:21245295 GO_REF:0000107 MGI:4939876 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Cd36 CD36 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16061696)		 Ensembl
RGD		 PMID:16061696 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Clec4m C-type lectin domain family 4 member M acts_upstream_of_or_within ISO (PMID:14707091) RGD PMID:14707091 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:11567029)
(PMID:14707091)
GO_REF:0000033		 RGD
GO_Central		 PMID:11567029 PMID:14707091 GO_REF:0000033 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Colec12 collectin sub-family member 12 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11564734)		 UniProt
RGD		 PMID:11564734 GO_REF:0000024 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618 		JBrowse link
G Fcgr1a Fc gamma receptor 1A acts_upstream_of_or_within ISO MGI:2664927|MGI:2679238 (PMID:11911823), (PMID:11911824), (PMID:9551950) RGD PMID:9551950 PMID:11911823 PMID:11911824 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fcgr2a Fc gamma receptor 2A acts_upstream_of_or_within ISO MGI:1861924 (PMID:8769481), (PMID:9743367), (PMID:9834201) RGD PMID:8769481 PMID:9743367 PMID:9834201 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within ISO (PMID:11911823), (PMID:11911824), (PMID:8769481), (PMID:9551950), (PMID:9743367), (PMID:9834201) RGD PMID:8769481 PMID:9551950 PMID:9743367 PMID:9834201 PMID:11911823 More... Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 4:163,288,228...163,301,977
Ensembl chr 4:163,288,229...163,300,535 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 IMP RGD PMID:12016218 RGD:1304245 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sirpa signal-regulatory protein alpha acts_upstream_of_or_within ISO (PMID:14634079) RGD PMID:14634079 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:32514138) RGD PMID:32514138 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tub TUB bipartite transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861349 (PMID:19837063), (PMID:20978472)		 Ensembl
RGD		 PMID:19837063 PMID:20978472 GO_REF:0000107 NCBI chr 1:163,008,198...163,030,958
Ensembl chr 1:162,951,931...163,026,812 		JBrowse link
G Tulp1 TUB like protein 1 acts_upstream_of_or_within ISO MGI:1859921 (PMID:19837063), (PMID:20978472) RGD PMID:19837063 PMID:20978472 NCBI chr20:6,412,170...6,424,103
Ensembl chr20:6,412,171...6,424,073 		JBrowse link
opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd47 Cd47 molecule acts_upstream_of_or_within ISO (PMID:14634079) RGD PMID:14634079 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Ptx3 pentraxin 3 acts_upstream_of_or_within ISO (PMID:14726497) RGD PMID:14726497 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Sftpa1 surfactant protein A1 involved_in ISO (PMID:21123169) RGD PMID:21123169 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sftpd surfactant protein D IDA RGD PMID:19017984 RGD:4143523 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO MGI:3026870 (PMID:14691481) RGD PMID:14691481 NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996 		JBrowse link
positive regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Colec10 collectin subfamily member 10 involved_in ISO (PMID:24174618) RGD PMID:24174618 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675 		JBrowse link
G Colec11 collectin sub-family member 11 involved_in ISO (PMID:24174618) RGD PMID:24174618 NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145 		JBrowse link
G Fcnb ficolin B involved_in ISO (PMID:16116205) RGD PMID:16116205 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) RGD PMID:22966085 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Myo18a myosin XVIIIa involved_in ISO
IEA		 (PMID:21123169)
(MGI:5810257|PMID:21123169)
GO_REF:0000107		 RGD
Ensembl		 PMID:21123169 GO_REF:0000107 MGI:5810257 NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISS
ISO		 GO_REF:0000024
(MGI:3841317|PMID:19342668)		 UniProt
RGD		 PMID:19342668 GO_REF:0000024 MGI:3841317 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
recognition of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcnb ficolin B involved_in ISO (PMID:15804047) RGD PMID:15804047 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2686850 (PMID:10811223), (PMID:14645847)		 Ensembl
RGD		 PMID:10811223 PMID:14645847 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
G Megf10 multiple EGF-like domains 10 acts_upstream_of_or_within ISO (PMID:19915564) RGD PMID:19915564 NCBI chr18:50,605,231...50,755,441
Ensembl chr18:50,605,656...50,754,456 		JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 acts_upstream_of_or_within ISO (PMID:19915564) RGD PMID:19915564 NCBI chr 2:173,206,298...173,234,106
Ensembl chr 2:173,207,664...173,227,440 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO
IEA
IBA
IDA
ISS		 (PMID:9211901)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
PMID:12016218
GO_REF:0000024		 RGD
TreeGrafter
GO_Central
Ensembl
BHF-UCL		 PMID:9211901 PMID:12016218 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:1304245 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:22333221)		 Ensembl
RGD		 PMID:22333221 GO_REF:0000107 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA		 (PMID:22333221)
GO_REF:0000107		 RGD
Ensembl		 PMID:22333221 GO_REF:0000107 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cell recognition 166
        phagocytosis, recognition 30
          opsonization + 13
          recognition of apoptotic cell 5
Path 2
Term Annotations click to browse term
  biological_process 20413
    localization 5751
      establishment of localization 5029
        transport 4708
          vesicle-mediated transport 1691
            endocytosis 753
              phagocytosis 250
                phagocytosis, recognition 30
                  opsonization + 13
                  recognition of apoptotic cell 5
paths to the root