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ONTOLOGY REPORT - ANNOTATIONS


Term:phagocytosis, recognition
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Accession:GO:0006910 term browser browse the term
Definition:The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment:Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms:exact_synonym: recognition of phagocytosed substance by phagocytic cell



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phagocytosis, recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:1,582,321...1,658,639
Ensembl chr 4:1,582,330...1,647,573
JBrowse link
G CD36 CD36 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3587138|PMID:16061696) Ensembl
MGI
PMID:16061696 GO_REF:0000107 MGI:3587138 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:3027358|PMID:14707091)
GO_Central
MGI
Ensembl
GO_Central
PMID:14707091 PMID:21873635 GO_REF:0000107 MGI:3027358 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,954...61,846,434
JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:105,808,157...106,000,197
Ensembl chr 6:105,808,221...106,007,730
JBrowse link
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) acts_upstream_of_or_within ISO (MGI:2664488|PMID:11911824)
(MGI:2679188|PMID:9551950), (MGI:2679189|PMID:11911823)
MGI PMID:9551950 PMID:11911823 PMID:11911824 MGI:2664488 MGI:2679188 MGI:2679189 NCBI chr 4:99,233,632...99,242,531
Ensembl chr 4:99,233,611...99,242,586
JBrowse link
G LOC100523213 immunoglobulin lambda-like polypeptide 5 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr14:49,951,542...49,960,517 JBrowse link
G LOC102160313 T-cell receptor delta chain C region involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 7:76,554,354...76,565,679
Ensembl chr 7:76,469,954...76,673,728
JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2681272|PMID:12000961) Ensembl
Ensembl
MGI
PMID:12000961 GO_REF:0000107 MGI:2681272 NCBI chr 7:54,539,970...54,554,885
Ensembl chr 7:54,539,970...54,571,747
JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO RGD PMID:12016218 RGD:1304245 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568
JBrowse link
G SIRPA signal regulatory protein alpha acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chr17:33,566,270...33,611,375 JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516
JBrowse link
G TUB TUB bipartite transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4441109|PMID:19837063)
(MGI:4867371|PMID:20978472)
Ensembl
Ensembl
MGI
PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chr 9:1,183,821...1,260,209
Ensembl chr 9:1,183,822...1,206,274
JBrowse link
G TULP1 TUB like protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4867371|PMID:20978472)
(MGI:4441109|PMID:19837063)
Ensembl
Ensembl
MGI
PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chr 7:31,362,670...31,379,948
Ensembl chr 7:31,361,873...31,379,204
JBrowse link
opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228
JBrowse link
G CD47 CD47 molecule acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chr13:151,427,933...151,488,064
Ensembl chr13:151,429,288...151,488,544
JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970
JBrowse link
G PTX3 pentraxin 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3037598|PMID:14726497) Ensembl
Ensembl
MGI
PMID:14726497 GO_REF:0000107 MGI:3037598 NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
JBrowse link
G SFTPA1 surfactant protein A1 involved_in ISO (PMID:21123169) UniProt PMID:21123169 NCBI chr14:82,091,178...82,095,393
Ensembl chr14:82,091,178...82,095,393
JBrowse link
G SFTPD surfactant protein D ISO RGD PMID:19017984 RGD:4143523 NCBI chr14:82,051,400...82,069,258
Ensembl chr14:82,051,451...82,067,976
JBrowse link
G SPON2 spondin 2 acts_upstream_of_or_within ISO (MGI:2686801|PMID:14691481) MGI PMID:14691481 MGI:2686801 NCBI chr 8:447,176...450,829
Ensembl chr 8:447,180...450,538
JBrowse link
positive regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228
JBrowse link
G COLEC10 collectin subfamily member 10 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:19,692,990...20,143,740
Ensembl chr 4:19,692,830...19,744,135
JBrowse link
G COLEC11 collectin subfamily member 11 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:131,226,941...131,254,555
Ensembl chr 3:131,226,956...131,254,553
JBrowse link
G FCN1 ficolin (collagen/fibrinogen domain containing) 1 involved_in ISO (PMID:11907111) ComplexPortal PMID:11907111 NCBI chr 1:274,125,666...274,132,917 JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chr13:124,938,469...125,028,440
Ensembl chr13:124,955,030...125,054,463
JBrowse link
G MASP2 MBL associated serine protease 2 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chr 6:71,224,637...71,243,041
Ensembl chr 6:71,224,637...71,243,874
JBrowse link
G MBL2 mannose binding lectin 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083
JBrowse link
G MYO18A myosin XVIIIA involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:45,282,903...45,429,819 JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 6:78,365,697...78,376,383
Ensembl chr 6:78,302,062...78,376,220
JBrowse link
recognition of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCN1 ficolin (collagen/fibrinogen domain containing) 1 involved_in ISO (PMID:15804047) UniProt PMID:15804047 NCBI chr 1:274,125,666...274,132,917 JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970
JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1855743|PMID:10811223)
(MGI:2682078|PMID:14645847)
Ensembl
Ensembl
MGI
PMID:10811223 PMID:14645847 GO_REF:0000107 MGI:1855743 MGI:2682078 NCBI chr12:4,809,014...4,819,853
Ensembl chr12:4,809,118...4,818,043
JBrowse link
G MEGF10 multiple EGF like domains 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4414741|PMID:19915564) MGI
Ensembl
PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chr 2:130,226,222...130,403,960
Ensembl chr 2:130,189,556...130,401,077
JBrowse link
G PEAR1 platelet endothelial aggregation receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4414741|PMID:19915564) Ensembl
Ensembl
MGI
PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chr 4:93,178,854...93,205,186
Ensembl chr 4:93,177,158...93,205,155
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568
JBrowse link
regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:67,726,159...67,774,369
Ensembl chr 9:67,726,154...67,829,220
JBrowse link
G C4BPA complement component 4 binding protein, alpha involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 9:67,815,544...67,827,509
Ensembl chr 9:67,815,340...67,827,407
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:67,716,205...67,725,785
Ensembl chr 9:67,716,283...67,725,783
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17341
    cellular process 16374
      cell recognition 157
        phagocytosis, recognition 34
          opsonization + 18
          recognition of apoptotic cell 6
Path 2
Term Annotations click to browse term
  biological_process 17341
    localization 5350
      establishment of localization 4691
        transport 4525
          vesicle-mediated transport 1569
            endocytosis 588
              phagocytosis, recognition 34
                opsonization + 18
                recognition of apoptotic cell 6
paths to the root