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ONTOLOGY REPORT - ANNOTATIONS

Term:phagocytosis, recognition
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Accession:GO:0006910 term browser browse the term
Definition:The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment:Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms:exact_synonym: recognition of phagocytosed substance by phagocytic cell


show annotations for term's descendants           Sort by:
phagocytosis, recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16061696) Ensembl
MGI		 PMID:16061696 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CLEC4M C-type lectin domain family 4 member M acts_upstream_of_or_within ISO (PMID:14707091) MGI PMID:14707091 NCBI chr19:7,763,243...7,769,605
Ensembl chr19:7,763,210...7,769,605 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within		 IDA
ISO
IBA
IEA		 (PMID:11567029)
(PMID:14707091)		 UniProt
MGI
GO_Central
TreeGrafter		 PMID:11567029 PMID:14707091 GO_REF:0000033 GO_REF:0000118 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IDA
IBA		 (PMID:11564734) UniProt
GO_Central		 PMID:11564734 GO_REF:0000033 NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722 		JBrowse link
G FCGR1A Fc gamma receptor Ia involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11911823), (PMID:9551950)
(PMID:11911824)		 Ensembl
MGI		 PMID:9551950 PMID:11911823 PMID:11911824 GO_REF:0000107 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675 		JBrowse link
G IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) acts_upstream_of_or_within ISO (PMID:11911823), (PMID:11911824), (PMID:8769481), (PMID:9551950), (PMID:9743367), (PMID:9834201) MGI PMID:8769481 PMID:9551950 PMID:9743367 PMID:9834201 PMID:11911823 More... NCBI chr14:105,741,473...105,743,070
Ensembl chr14:105,736,343...105,743,071 		JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO RGD PMID:12016218 RGD:1304245 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SIRPA signal regulatory protein alpha acts_upstream_of_or_within ISO (PMID:14634079) MGI PMID:14634079 NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TUB TUB bipartite transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20978472)
(PMID:19837063)		 Ensembl
MGI		 PMID:19837063 PMID:20978472 GO_REF:0000107 NCBI chr11:8,019,059...8,106,243
Ensembl chr11:8,019,244...8,106,243 		JBrowse link
G TULP1 TUB like protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20978472)
(PMID:19837063)		 Ensembl
MGI		 PMID:19837063 PMID:20978472 GO_REF:0000107 NCBI chr 6:35,497,874...35,512,896
Ensembl chr 6:35,497,874...35,512,896 		JBrowse link
opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4B complement C4B (Chido/Rodgers blood group) involved_in TAS (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418 		JBrowse link
G C4B_2 complement component 4B (Chido/Rodgers blood group), copy 2 involved_in TAS (PMID:22333221) BHF-UCL PMID:22333221
G CD47 CD47 molecule acts_upstream_of_or_within ISO (PMID:14634079) MGI PMID:14634079 NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862 		JBrowse link
G CRP C-reactive protein involved_in TAS (PMID:2477488) BHF-UCL PMID:2477488 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G FCN2 ficolin 2 involved_in IDA (PMID:8576206) UniProt PMID:8576206 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IC
ISS		 (PMID:12932360)
(PMID:2477488)		 BHF-UCL PMID:2477488 PMID:12932360 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in TAS (PMID:2477488) BHF-UCL PMID:2477488 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G PTX3 pentraxin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14726497) Ensembl
MGI		 PMID:14726497 GO_REF:0000107 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
G SFTPA1 surfactant protein A1 involved_in IMP (PMID:21123169) UniProt PMID:21123169 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPD surfactant protein D ISO RGD PMID:19017984 RGD:4143523 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G SPON2 spondin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14691481) Ensembl
MGI		 PMID:14691481 GO_REF:0000107 NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962 		JBrowse link
positive regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFP complement factor properdin involved_in NAS (PMID:23901101) ComplexPortal PMID:23901101 NCBI chr  X:47,623,282...47,630,305
Ensembl chr  X:47,623,172...47,630,305 		JBrowse link
G COLEC10 collectin subfamily member 10 involved_in IDA (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 8:118,952,263...119,108,455
Ensembl chr 8:118,995,452...119,108,455 		JBrowse link
G COLEC11 collectin subfamily member 11 involved_in IDA (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 2:3,595,112...3,644,644
Ensembl chr 2:3,594,832...3,644,644 		JBrowse link
G FCN1 ficolin 1 involved_in IDA (PMID:16116205) ComplexPortal PMID:16116205 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912 		JBrowse link
G FCN2 ficolin 2 involved_in IDA (PMID:10679061) ComplexPortal PMID:10679061 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FCN3 ficolin 3 involved_in IDA (PMID:11907111) ComplexPortal PMID:11907111 NCBI chr 1:27,369,110...27,374,824
Ensembl chr 1:27,369,110...27,374,824 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in IDA (PMID:22966085) ComplexPortal PMID:22966085 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MYO18A myosin XVIIIA involved_in IMP (PMID:21123169) UniProt PMID:21123169 NCBI chr17:29,071,122...29,180,398
Ensembl chr17:29,071,122...29,180,398 		JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
recognition of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCN1 ficolin 1 involved_in IDA (PMID:15804047) UniProt PMID:15804047 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912 		JBrowse link
G FCN2 ficolin 2 involved_in IDA (PMID:15804047) UniProt PMID:15804047 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FCN3 ficolin 3 involved_in IDA (PMID:15804047) UniProt PMID:15804047 NCBI chr 1:27,369,110...27,374,824
Ensembl chr 1:27,369,110...27,374,824 		JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14645847)
(PMID:10811223)		 Ensembl
MGI		 PMID:10811223 PMID:14645847 GO_REF:0000107 NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799 		JBrowse link
G MEGF10 multiple EGF like domains 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19915564) Ensembl
MGI		 PMID:19915564 GO_REF:0000107 NCBI chr 5:127,229,300...127,461,222
Ensembl chr 5:127,290,796...127,465,737 		JBrowse link
G PEAR1 platelet endothelial aggregation receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19915564) Ensembl
MGI		 PMID:19915564 GO_REF:0000107 NCBI chr 1:156,893,718...156,916,429
Ensembl chr 1:156,893,698...156,916,429 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IDA
IEA
IBA		 (PMID:9211901) BHF-UCL
TreeGrafter
GO_Central		 PMID:9211901 GO_REF:0000033 GO_REF:0000118 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IDA (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 1:207,104,233...207,144,972
Ensembl chr 1:207,104,233...207,144,972 		JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IDA (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 1:207,088,860...207,099,993
Ensembl chr 1:207,088,860...207,099,993 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      cell recognition 189
        phagocytosis, recognition 35
          opsonization + 20
          recognition of apoptotic cell 7
Path 2
Term Annotations click to browse term
  biological_process 19669
    localization 5869
      establishment of localization 5161
        transport 4818
          vesicle-mediated transport 1750
            endocytosis 802
              phagocytosis 270
                phagocytosis, recognition 35
                  opsonization + 20
                  recognition of apoptotic cell 7
paths to the root