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ONTOLOGY REPORT - ANNOTATIONS


Term:phagocytosis, recognition
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Accession:GO:0006910 term browser browse the term
Definition:The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment:Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms:exact_synonym: recognition of phagocytosed substance by phagocytic cell



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phagocytosis, recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in ISO (MGI:4939876|PMID:21245295) UniProt PMID:21245295 MGI:4939876 NCBI chr13:36,627,791...36,649,013
Ensembl chr13:36,614,498...36,690,936
JBrowse link
G CD36 CD36 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3587138|PMID:16061696) Ensembl
MGI
Ensembl
PMID:16061696 GO_REF:0000107 MGI:3587138 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639
JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:3027358|PMID:14707091)
GO_Central
MGI
Ensembl
PMID:14707091 PMID:21873635 GO_REF:0000107 MGI:3027358 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:35,896,421...35,920,649
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:67,192,191...67,373,524
Ensembl chr 7:67,193,626...67,372,755
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2664488|PMID:11911824)
(MGI:2679188|PMID:9551950), (MGI:2679189|PMID:11911823)
MGI
Ensembl
PMID:9551950 PMID:11911823 PMID:11911824 GO_REF:0000107 MGI:2664488 MGI:2679188 MGI:2679189 NCBI chr17:59,073,139...59,102,023
Ensembl chr17:59,092,933...59,102,015
JBrowse link
G IGHM immunoglobulin heavy constant mu involved_in IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr 8:72,977,146...72,981,735 JBrowse link
G LOC100687054 immunoglobulin lambda-like polypeptide 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:28,793,360...28,804,589 JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing acts_upstream_of_or_within ISO (MGI:2681272|PMID:12000961) MGI PMID:12000961 MGI:2681272 NCBI chr 3:52,054,243...52,064,423
Ensembl chr 3:52,054,831...52,080,240
JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO RGD PMID:12016218 RGD:1304245 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468
JBrowse link
G SIRPA signal regulatory protein alpha acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chr24:19,094,930...19,136,655 JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174
JBrowse link
G TUB TUB bipartite transcription factor acts_upstream_of_or_within ISO (MGI:4867371|PMID:20978472)
(MGI:4441109|PMID:19837063)
MGI PMID:19837063 PMID:20978472 MGI:4441109 MGI:4867371 NCBI chr21:31,566,095...31,629,545
Ensembl chr21:31,566,130...31,625,101
JBrowse link
G TULP1 TUB like protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4867371|PMID:20978472)
(MGI:4441109|PMID:19837063)
MGI
Ensembl
PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chr12:4,632,580...4,644,313
Ensembl chr12:4,633,098...4,645,994
JBrowse link
opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G CD47 CD47 molecule acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chr33:13,315,984...13,362,971
Ensembl chr33:13,319,266...13,363,580
JBrowse link
G LOC610540 pulmonary surfactant-associated protein A-like involved_in ISO (PMID:21123169) UniProt PMID:21123169 NCBI chr 4:29,430,139...29,434,640 JBrowse link
G PTX3 pentraxin 3 acts_upstream_of_or_within ISO (MGI:3037598|PMID:14726497) MGI PMID:14726497 MGI:3037598 NCBI chr23:50,952,835...50,958,607
Ensembl chr23:50,952,885...50,958,167
JBrowse link
G SFTPD surfactant protein D ISO RGD PMID:19017984 RGD:4143523 NCBI chr 4:29,394,755...29,407,499
Ensembl chr 4:29,394,678...29,407,293
JBrowse link
G SPON2 spondin 2 acts_upstream_of_or_within ISO (MGI:2686801|PMID:14691481) MGI PMID:14691481 MGI:2686801 NCBI chr 3:91,411,245...91,421,245 JBrowse link
positive regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G COLEC10 collectin subfamily member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:18,291,168...18,331,918
Ensembl chr13:18,291,051...18,330,617
JBrowse link
G COLEC11 collectin subfamily member 11 involved_in ISO (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr17:2,147,679...2,180,096
Ensembl chr17:2,147,882...2,180,098
JBrowse link
G FCN2 ficolin 2 involved_in ISO (PMID:16116205) ComplexPortal PMID:16116205 NCBI chr 9:50,868,942...50,876,001
Ensembl chr 9:50,868,973...50,875,792
JBrowse link
G FCN3 ficolin 3 involved_in ISO (PMID:11907111) ComplexPortal PMID:11907111
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chr34:19,689,426...19,750,669
Ensembl chr34:19,691,630...19,750,587
JBrowse link
G MASP2 MBL associated serine protease 2 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chr 2:84,976,366...84,987,376
Ensembl chr 2:84,976,456...84,989,797
JBrowse link
G MBL1 mannose binding lectin 1 involved_in ISO (PMID:22966085) ComplexPortal PMID:22966085 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G MYO18A myosin XVIIIA involved_in ISO (PMID:21123169)
(MGI:5810257|PMID:21123169)
UniProt PMID:21123169 MGI:5810257 NCBI chr 9:43,226,170...43,325,026
Ensembl chr 9:43,227,187...43,322,545
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983
JBrowse link
recognition of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCN2 ficolin 2 involved_in ISO (PMID:15804047) UniProt PMID:15804047 NCBI chr 9:50,868,942...50,876,001
Ensembl chr 9:50,868,973...50,875,792
JBrowse link
G FCN3 ficolin 3 involved_in ISO (PMID:15804047) UniProt PMID:15804047
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1855743|PMID:10811223)
(MGI:2682078|PMID:14645847)
MGI
Ensembl
Ensembl
PMID:10811223 PMID:14645847 GO_REF:0000107 MGI:1855743 MGI:2682078 NCBI chr 9:4,037,307...4,076,119
Ensembl chr 9:4,037,439...4,076,123
JBrowse link
G MEGF10 multiple EGF like domains 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4414741|PMID:19915564) MGI
Ensembl
Ensembl
PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chr11:16,359,648...16,574,882
Ensembl chr11:16,378,669...16,617,335
JBrowse link
G PEAR1 platelet endothelial aggregation receptor 1 acts_upstream_of_or_within ISO (MGI:4414741|PMID:19915564) MGI PMID:19915564 MGI:4414741 NCBI chr 7:41,110,925...41,130,532
Ensembl chr 7:41,110,909...41,123,390
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468
JBrowse link
regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 7:6,239,036...6,268,934
Ensembl chr 7:6,241,102...6,268,910
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chr 7:6,224,962...6,236,925
Ensembl chr 7:6,225,188...6,236,918
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17250
    cellular process 16256
      cell recognition 160
        phagocytosis, recognition 34
          opsonization + 17
          recognition of apoptotic cell 6
Path 2
Term Annotations click to browse term
  biological_process 17250
    localization 5414
      establishment of localization 4756
        transport 4590
          vesicle-mediated transport 1571
            endocytosis 593
              phagocytosis, recognition 34
                opsonization + 17
                recognition of apoptotic cell 6
paths to the root