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ONTOLOGY REPORT - ANNOTATIONS


Term:phagocytosis, recognition
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Accession:GO:0006910 term browser browse the term
Definition:The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment:Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms:exact_synonym: recognition of phagocytosed substance by phagocytic cell



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phagocytosis, recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:139,154,065...139,251,115
Ensembl chr 8:142,220,827...142,301,070
JBrowse link
G CD36 CD36 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3587138|PMID:16061696) MGI
Ensembl
PMID:16061696 GO_REF:0000107 MGI:3587138 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3027358|PMID:14707091) Ensembl
MGI
PMID:14707091 GO_REF:0000107 MGI:3027358 NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452
JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:13,819,575...14,001,383
Ensembl chr18:17,461,678...17,640,721
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia acts_upstream_of_or_within ISO (MGI:2664488|PMID:11911824)
(MGI:2679188|PMID:9551950), (MGI:2679189|PMID:11911823)
MGI PMID:9551950 PMID:11911823 PMID:11911824 MGI:2664488 MGI:2679188 MGI:2679189 NCBI chr 1:125,127,073...125,136,911
Ensembl chr 1:128,805,484...128,814,220
JBrowse link
G LOC100978434 C-type lectin domain family 4 member M acts_upstream_of_or_within ISO (MGI:3027358|PMID:14707091) MGI PMID:14707091 MGI:3027358 NCBI chr19:7,062,961...7,069,381 JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2681272|PMID:12000961) MGI
Ensembl
PMID:12000961 GO_REF:0000107 MGI:2681272 NCBI chr15:67,587,360...67,602,029
Ensembl chr15:86,795,135...86,809,876
JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO RGD PMID:12016218 RGD:1304245 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767
JBrowse link
G SIRPA signal regulatory protein alpha acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578
JBrowse link
G TUB TUB bipartite transcription factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4441109|PMID:19837063)
(MGI:4867371|PMID:20978472)
MGI
Ensembl
PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chr11:8,135,981...8,223,414
Ensembl chr11:7,882,680...7,969,434
JBrowse link
G TULP1 TUB like protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4441109|PMID:19837063)
(MGI:4867371|PMID:20978472)
MGI
Ensembl
PMID:19837063 PMID:20978472 GO_REF:0000107 MGI:4441109 MGI:4867371 NCBI chr 6:35,058,422...35,073,472
Ensembl chr 6:36,151,747...36,166,160
JBrowse link
opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CD47 CD47 molecule acts_upstream_of_or_within ISO (MGI:2680858|PMID:14634079) MGI PMID:14634079 MGI:2680858 NCBI chr 3:105,170,246...105,217,603
Ensembl chr 3:112,104,037...112,143,522
JBrowse link
G FCN2 ficolin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
JBrowse link
G PTX3 pentraxin 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3037598|PMID:14726497) MGI
Ensembl
PMID:14726497 GO_REF:0000107 MGI:3037598 NCBI chr 3:154,485,470...154,492,293
Ensembl chr 3:162,537,577...162,543,652
JBrowse link
G SFTPA1 surfactant protein A1 involved_in ISO (PMID:21123169) UniProt PMID:21123169 NCBI chr10:76,571,312...76,575,820 JBrowse link
G SFTPD surfactant protein D ISO RGD PMID:19017984 RGD:4143523 NCBI chr10:76,275,147...76,318,952
Ensembl chr10:78,965,252...78,974,181
JBrowse link
G SPON2 spondin 2 acts_upstream_of_or_within ISO (MGI:2686801|PMID:14691481) MGI PMID:14691481 MGI:2686801 NCBI chr 4:1,309,473...1,351,529
Ensembl chr 4:1,195,848...1,200,400
JBrowse link
positive regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G COLEC10 collectin subfamily member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:115,758,592...115,798,548
Ensembl chr 8:118,277,484...118,317,271
JBrowse link
G COLEC11 collectin subfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:3,610,679...3,659,739
Ensembl chr2A:3,529,358...3,579,517
JBrowse link
G FCN1 ficolin 1 involved_in ISO (PMID:16116205) ComplexPortal PMID:16116205 NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111
JBrowse link
G FCN2 ficolin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
JBrowse link
G FCN3 ficolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,620,373...26,636,424
Ensembl chr 1:27,676,866...27,683,861
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chr 3:184,241,611...184,317,272
Ensembl chr 3:192,707,784...192,782,196
JBrowse link
G MASP2 MBL associated serine protease 2 involved_in ISO (PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618) ComplexPortal PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618 NCBI chr 1:9,787,565...9,810,276
Ensembl chr 1:11,009,760...11,030,734
JBrowse link
G MBL2 mannose binding lectin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G MYO18A myosin XVIIIA involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,593,787...27,700,801
Ensembl chr17:28,116,279...28,208,301
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (MGI:3841317|PMID:19342668) UniProt PMID:19342668 MGI:3841317 NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840
JBrowse link
recognition of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCN1 ficolin 1 involved_in ISO (PMID:15804047) UniProt PMID:15804047 NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111
JBrowse link
G FCN2 ficolin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
JBrowse link
G FCN3 ficolin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,620,373...26,636,424
Ensembl chr 1:27,676,866...27,683,861
JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2682078|PMID:14645847)
(MGI:1855743|PMID:10811223)
MGI
Ensembl
PMID:10811223 PMID:14645847 GO_REF:0000107 MGI:1855743 MGI:2682078 NCBI chr17:70,789,922...70,803,791
Ensembl chr17:76,356,142...76,370,117
JBrowse link
G MEGF10 multiple EGF like domains 10 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4414741|PMID:19915564) MGI
Ensembl
PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chr 5:122,639,155...122,877,324
Ensembl chr 5:128,466,095...128,641,043
JBrowse link
G PEAR1 platelet endothelial aggregation receptor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4414741|PMID:19915564) MGI
Ensembl
PMID:19915564 GO_REF:0000107 MGI:4414741 NCBI chr 1:132,236,550...132,259,273
Ensembl chr 1:136,069,341...136,080,165
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in ISO (PMID:9211901)
PMID:12016218
BHF-UCL PMID:9211901 PMID:12016218 RGD:1304245 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767
JBrowse link
regulation of opsonization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,691,574...182,703,004
Ensembl chr 1:186,970,253...186,981,024
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15365
    cellular process 14213
      cell recognition 137
        phagocytosis, recognition 33
          opsonization + 18
          recognition of apoptotic cell 7
Path 2
Term Annotations click to browse term
  biological_process 15365
    localization 4832
      establishment of localization 4214
        transport 4048
          vesicle-mediated transport 1365
            endocytosis 509
              phagocytosis, recognition 33
                opsonization + 18
                recognition of apoptotic cell 7
paths to the root