ONTOLOGY REPORT - ANNOTATIONS
Term: phagocytosis, recognition
Accession: GO:0006910
browse the term
Definition: The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Comment: Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.
Synonyms: exact_synonym: recognition of phagocytosed substance by phagocytic cell
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ADGRB1
adhesion G protein-coupled receptor B1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 8:139,154,065...139,251,115
Ensembl chr 8:142,220,827...142,301,070
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CD36
CD36 molecule
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:3587138|PMID:16061696)
MGI Ensembl
PMID:16061696
GO_REF:0000107 MGI:3587138
NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
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CLEC7A
C-type lectin domain containing 7A
involved_in acts_upstream_of_or_within
IEA ISO
(MGI:3027358|PMID:14707091)
Ensembl MGI
PMID:14707091
GO_REF:0000107 MGI:3027358
NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452
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COLEC12
collectin subfamily member 12
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr18:13,819,575...14,001,383
Ensembl chr18:17,461,678...17,640,721
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FCGR1A
Fc fragment of IgG receptor Ia
acts_upstream_of_or_within
ISO
(MGI:2664488|PMID:11911824) (MGI:2679188|PMID:9551950), (MGI:2679189|PMID:11911823)
MGI
PMID:9551950 PMID:11911823 PMID:11911824
MGI:2664488 MGI:2679188 MGI:2679189
NCBI chr 1:125,127,073...125,136,911
Ensembl chr 1:128,805,484...128,814,220
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LOC100978434
C-type lectin domain family 4 member M
acts_upstream_of_or_within
ISO
(MGI:3027358|PMID:14707091)
MGI
PMID:14707091
MGI:3027358
NCBI chr19:7,062,961...7,069,381
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MFGE8
milk fat globule EGF and factor V/VIII domain containing
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:2681272|PMID:12000961)
MGI Ensembl
PMID:12000961
GO_REF:0000107 MGI:2681272
NCBI chr15:67,587,360...67,602,029
Ensembl chr15:86,795,135...86,809,876
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SCARB1
scavenger receptor class B member 1
ISO
RGD
PMID:12016218
RGD:1304245
NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767
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SIRPA
signal regulatory protein alpha
acts_upstream_of_or_within
ISO
(MGI:2680858|PMID:14634079)
MGI
PMID:14634079
MGI:2680858
NCBI chr20:2,006,994...2,052,894
Ensembl chr20:1,773,271...1,818,106
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TREM2
triggering receptor expressed on myeloid cells 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578
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TUB
TUB bipartite transcription factor
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:4441109|PMID:19837063) (MGI:4867371|PMID:20978472)
MGI Ensembl
PMID:19837063 PMID:20978472
GO_REF:0000107 MGI:4441109 MGI:4867371
NCBI chr11:8,135,981...8,223,414
Ensembl chr11:7,882,680...7,969,434
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TULP1
TUB like protein 1
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:4441109|PMID:19837063) (MGI:4867371|PMID:20978472)
MGI Ensembl
PMID:19837063 PMID:20978472
GO_REF:0000107 MGI:4441109 MGI:4867371
NCBI chr 6:35,058,422...35,073,472
Ensembl chr 6:36,151,747...36,166,160
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C3
complement C3
involved_in
ISO
(PMID:6225800)
ComplexPortal
PMID:6225800
NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
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CD47
CD47 molecule
acts_upstream_of_or_within
ISO
(MGI:2680858|PMID:14634079)
MGI
PMID:14634079
MGI:2680858
NCBI chr 3:105,170,246...105,217,603
Ensembl chr 3:112,104,037...112,143,522
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FCN2
ficolin 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
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PTX3
pentraxin 3
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:3037598|PMID:14726497)
MGI Ensembl
PMID:14726497
GO_REF:0000107 MGI:3037598
NCBI chr 3:154,485,470...154,492,293
Ensembl chr 3:162,537,577...162,543,652
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SFTPA1
surfactant protein A1
involved_in
ISO
(PMID:21123169)
UniProt
PMID:21123169
NCBI chr10:76,571,312...76,575,820
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SFTPD
surfactant protein D
ISO
RGD
PMID:19017984
RGD:4143523
NCBI chr10:76,275,147...76,318,952
Ensembl chr10:78,965,252...78,974,181
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SPON2
spondin 2
acts_upstream_of_or_within
ISO
(MGI:2686801|PMID:14691481)
MGI
PMID:14691481
MGI:2686801
NCBI chr 4:1,309,473...1,351,529
Ensembl chr 4:1,195,848...1,200,400
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C3
complement C3
involved_in
ISO
(PMID:6225800)
ComplexPortal
PMID:6225800
NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
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COLEC10
collectin subfamily member 10
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 8:115,758,592...115,798,548
Ensembl chr 8:118,277,484...118,317,271
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COLEC11
collectin subfamily member 11
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr2A:3,610,679...3,659,739
Ensembl chr2A:3,529,358...3,579,517
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FCN1
ficolin 1
involved_in
ISO
(PMID:16116205)
ComplexPortal
PMID:16116205
NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111
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FCN2
ficolin 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
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FCN3
ficolin 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:26,620,373...26,636,424
Ensembl chr 1:27,676,866...27,683,861
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MASP1
MBL associated serine protease 1
involved_in
ISO
(PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618)
ComplexPortal
PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618
NCBI chr 3:184,241,611...184,317,272
Ensembl chr 3:192,707,784...192,782,196
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MASP2
MBL associated serine protease 2
involved_in
ISO
(PMID:10679061), (PMID:11907111), (PMID:16116205), (PMID:22966085), (PMID:24174618)
ComplexPortal
PMID:10679061 PMID:11907111 PMID:16116205 PMID:22966085 PMID:24174618
NCBI chr 1:9,787,565...9,810,276
Ensembl chr 1:11,009,760...11,030,734
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MBL2
mannose binding lectin 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
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MYO18A
myosin XVIIIA
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr17:27,593,787...27,700,801
Ensembl chr17:28,116,279...28,208,301
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PLA2G5
phospholipase A2 group V
involved_in
ISO
(MGI:3841317|PMID:19342668)
UniProt
PMID:19342668
MGI:3841317
NCBI chr 1:18,983,104...19,046,834
Ensembl chr 1:20,068,110...20,089,840
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FCN1
ficolin 1
involved_in
ISO
(PMID:15804047)
UniProt
PMID:15804047
NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111
G
FCN2
ficolin 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:105,995,807...106,020,389
Ensembl chr 9:134,997,038...135,018,992
G
FCN3
ficolin 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:26,620,373...26,636,424
Ensembl chr 1:27,676,866...27,683,861
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JMJD6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:2682078|PMID:14645847) (MGI:1855743|PMID:10811223)
MGI Ensembl
PMID:10811223 PMID:14645847
GO_REF:0000107 MGI:1855743 MGI:2682078
NCBI chr17:70,789,922...70,803,791
Ensembl chr17:76,356,142...76,370,117
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MEGF10
multiple EGF like domains 10
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:4414741|PMID:19915564)
MGI Ensembl
PMID:19915564
GO_REF:0000107 MGI:4414741
NCBI chr 5:122,639,155...122,877,324
Ensembl chr 5:128,466,095...128,641,043
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PEAR1
platelet endothelial aggregation receptor 1
acts_upstream_of_or_within involved_in
ISO IEA
(MGI:4414741|PMID:19915564)
MGI Ensembl
PMID:19915564
GO_REF:0000107 MGI:4414741
NCBI chr 1:132,236,550...132,259,273
Ensembl chr 1:136,069,341...136,080,165
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SCARB1
scavenger receptor class B member 1
involved_in
ISO
(PMID:9211901) PMID:12016218
BHF-UCL
PMID:9211901 PMID:12016218
RGD:1304245
NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767
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C4BPA
complement component 4 binding protein alpha
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898
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C4BPB
complement component 4 binding protein beta
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:182,691,574...182,703,004
Ensembl chr 1:186,970,253...186,981,024
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