pinocytosis - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS	{{ watchLinkText }}

Term:	pinocytosis	go back to main search page
Accession:	GO:0006907	browse the term
Definition:	An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
Synonyms:	exact_synonym:	fluid-phase endocytosis
	narrow_synonym:	clathrin-independent pinocytosis
	related_synonym:	single-organism pinocytosis
	alt_id:	GO:0006908; GO:1902536
	xref:	Wikipedia:Pinocytosis

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Rat (25) Mouse (24) Human (26) Chinchilla (22) Bonobo (23) Dog (24) Squirrel (23) Pig (24) All
Genes (25)

pinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dab2

DAB adaptor protein 2

acts_upstream_of_or_within

ISO

MGI:2387168 (MGI:3610714|PMID:16263760)

RGD

PMID:16263760

MGI:3610714

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

Ehd4

EH-domain containing 4

IMP

RGD

PMID:12011113

RGD:632501

NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002

Ppt1

palmitoyl-protein thioesterase 1

acts_upstream_of_or_within

ISO

(PMID:16542649)

RGD

PMID:16542649

NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048

Snx5

sorting nexin 5

involved_in

ISS
IBA
ISO

GO_REF:0000024
PMID:21873635
(PMID:18854019)

UniProt
RGD

PMID:18854019 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 3:131,621,709...131,641,205
Ensembl chr 3:131,621,880...131,641,192

macropinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Carmil1

capping protein regulator and myosin 1 linker 1

involved_in

ISO

(PMID:19846667)

RGD

PMID:19846667

NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326

dynamin 2

RGD

NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157

Dock2

dedicator of cytokinesis 2

involved_in

ISO

(MGI:5291858|PMID:21892172)

RGD

PMID:21892172

MGI:5291858

NCBI chr10:18,827,237...19,244,823

Mapkapk2

MAPK activated protein kinase 2

involved_in

ISO

(MGI:3761050|PMID:17906627)

RGD

PMID:17906627

MGI:3761050

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

Mapkapk3

MAPK activated protein kinase 3

involved_in

ISS
ISO

GO_REF:0000024
(MGI:3761050|PMID:17906627)

UniProt
RGD

PMID:17906627

GO_REF:0000024 MGI:3761050

NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568

Pycard

PYD and CARD domain containing

involved_in

ISO

(MGI:5291858|PMID:21892172)

RGD

PMID:21892172

MGI:5291858

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

Rab34

RAB34, member RAS oncogene family

NOT|involved_in

ISO

(PMID:17881736)

RGD

PMID:17881736

NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538

Snx33

sorting nexin 33

involved_in

ISO

(PMID:21048941)

RGD

PMID:21048941

NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538

negative regulation of macropinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Stx1b

syntaxin 1B

involved_in

ISS

GO_REF:0000024

ParkinsonsUK-UCL

GO_REF:0000024

NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280

negative regulation of pinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cav1

caveolin 1

involved_in

ISO
IEA

(PMID:23583380)
GO_REF:0000107

RGD
Ensembl

PMID:23583380

GO_REF:0000107

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Nr1h2

nuclear receptor subfamily 1, group H, member 2

involved_in

ISO

(PMID:17693624)

RGD

PMID:17693624

NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377

Nr1h3

nuclear receptor subfamily 1, group H, member 3

involved_in

ISO
IEA

(PMID:17693624)
GO_REF:0000107

RGD
Ensembl

PMID:17693624

GO_REF:0000107

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

Prom2

prominin 2

involved_in

ISO
IEA

(PMID:23583380)
GO_REF:0000107

RGD
Ensembl

PMID:23583380

GO_REF:0000107

NCBI chr 3:114,747,654...114,761,787
Ensembl chr 3:114,747,654...114,761,787

Tsc2

TSC complex subunit 2

IMP

RGD

PMID:9045618

RGD:11568652

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

positive regulation of macropinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Appl1

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

involved_in

ISO

(MGI:6270783|PMID:27219021)

RGD

PMID:27219021

MGI:6270783

NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692

Appl2

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

involved_in

ISO

(MGI:6270783|PMID:27219021)

RGD

PMID:27219021

MGI:6270783

NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754

positive regulation of pinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Actn4

actinin alpha 4

involved_in

ISO

(MGI:3687817|PMID:10954430)

RGD

PMID:10954430

MGI:3687817

NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847

Ankfy1

ankyrin repeat and FYVE domain containing 1

involved_in

ISO

(PMID:15328530)

RGD

PMID:15328530

NCBI chr10:57,312,246...57,383,964
Ensembl chr10:57,312,246...57,383,964

Axl

Axl receptor tyrosine kinase

involved_in

ISO

(PMID:21047970)

RGD

PMID:21047970

NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265

Cdc42

cell division cycle 42

involved_in

ISS
ISO

GO_REF:0000024
(MGI:5607692|PMID:24792215)

UniProt
RGD

PMID:24792215

GO_REF:0000024 MGI:5607692

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

Cln3

CLN3 lysosomal/endosomal transmembrane protein, battenin

involved_in

ISO

(MGI:5607692|PMID:24792215)

RGD

PMID:24792215

MGI:5607692

NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434

Ppt1

palmitoyl-protein thioesterase 1

involved_in

ISS
ISO

PMID:8895569
(PMID:16542649)

RGD

PMID:16542649 PMID:8895569

RGD:8553248

NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048

Term paths to the root

Path 1
Term	Annotations
biological_process	19492
cellular process	18340
vesicle-mediated transport	1672
endocytosis	690
pinocytosis	25
macropinocytosis +	11
micropinocytosis +	0
negative regulation of pinocytosis +	6
positive regulation of pinocytosis +	8
regulation of pinocytosis +	14
Path 2
Term	Annotations
biological_process	19492
localization	6447
establishment of localization	4864
transport	4700
vesicle-mediated transport	1672
endocytosis	690
pinocytosis	25
macropinocytosis +	11
micropinocytosis +	0
negative regulation of pinocytosis +	6
positive regulation of pinocytosis +	8
regulation of pinocytosis +	14

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Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

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ONTOLOGY REPORT - ANNOTATIONS