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ONTOLOGY REPORT - ANNOTATIONS


Term:pinocytosis
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Accession:GO:0006907 term browser browse the term
Definition:An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
Synonyms:exact_synonym: fluid-phase endocytosis
 narrow_synonym: clathrin-independent pinocytosis
 related_synonym: single-organism pinocytosis
 alt_id: GO:0006908;   GO:1902536
 xref: Wikipedia:Pinocytosis


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pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO MGI:2387168 (MGI:3610714|PMID:16263760) RGD PMID:16263760 MGI:3610714 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Ehd4 EH-domain containing 4 IMP RGD PMID:12011113 RGD:632501 NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within ISO (PMID:16542649) RGD PMID:16542649 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Snx5 sorting nexin 5 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:18854019)
UniProt
RGD
PMID:18854019 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:131,621,709...131,641,205
Ensembl chr 3:131,621,880...131,641,192
JBrowse link
macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:19846667) RGD PMID:19846667 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:18003703 RGD:9685165 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Dock2 dedicator of cytokinesis 2 involved_in ISO (MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:5291858 NCBI chr10:18,827,237...19,244,823 JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in ISO (MGI:3761050|PMID:17906627) RGD PMID:17906627 MGI:3761050 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3761050|PMID:17906627)
UniProt
RGD
PMID:17906627 GO_REF:0000024 MGI:3761050 NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:5291858 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rab34 RAB34, member RAS oncogene family NOT|involved_in ISO (PMID:17881736) RGD PMID:17881736 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538
JBrowse link
G Snx33 sorting nexin 33 involved_in ISO (PMID:21048941) RGD PMID:21048941 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538
JBrowse link
negative regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
JBrowse link
negative regulation of pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:23583380)
GO_REF:0000107
RGD
Ensembl
PMID:23583380 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:17693624)
GO_REF:0000107
RGD
Ensembl
PMID:17693624 GO_REF:0000107 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Prom2 prominin 2 involved_in ISO
IEA
(PMID:23583380)
GO_REF:0000107
RGD
Ensembl
PMID:23583380 GO_REF:0000107 NCBI chr 3:114,747,654...114,761,787
Ensembl chr 3:114,747,654...114,761,787
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:9045618 RGD:11568652 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
positive regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:6270783 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:6270783 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
positive regulation of pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 involved_in ISO (MGI:3687817|PMID:10954430) RGD PMID:10954430 MGI:3687817 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Ankfy1 ankyrin repeat and FYVE domain containing 1 involved_in ISO (PMID:15328530) RGD PMID:15328530 NCBI chr10:57,312,246...57,383,964
Ensembl chr10:57,312,246...57,383,964
JBrowse link
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:21047970) RGD PMID:21047970 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISS
ISO
GO_REF:0000024
(MGI:5607692|PMID:24792215)
UniProt
RGD
PMID:24792215 GO_REF:0000024 MGI:5607692 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5607692|PMID:24792215) RGD PMID:24792215 MGI:5607692 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISS
ISO
PMID:8895569
(PMID:16542649)
RGD PMID:16542649 PMID:8895569 RGD:8553248 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      vesicle-mediated transport 1672
        endocytosis 690
          pinocytosis 25
            macropinocytosis + 11
            micropinocytosis + 0
            negative regulation of pinocytosis + 6
            positive regulation of pinocytosis + 8
            regulation of pinocytosis + 14
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6447
      establishment of localization 4864
        transport 4700
          vesicle-mediated transport 1672
            endocytosis 690
              pinocytosis 25
                macropinocytosis + 11
                micropinocytosis + 0
                negative regulation of pinocytosis + 6
                positive regulation of pinocytosis + 8
                regulation of pinocytosis + 14
paths to the root