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ONTOLOGY REPORT - ANNOTATIONS


Term:pinocytosis
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Accession:GO:0006907 term browser browse the term
Definition:An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
Synonyms:exact_synonym: fluid-phase endocytosis
 narrow_synonym: clathrin-independent pinocytosis
 related_synonym: single-organism pinocytosis
 alt_id: GO:0006908;   GO:1902536
 xref: Wikipedia:Pinocytosis


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pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 ISO MGI:MGI:2387168 (MGI:MGI:3610714|PMID:16263760) RGD PMID:16263760 MGI:MGI:3610714 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Ehd4 EH-domain containing 4 IMP RGD PMID:12011113 RGD:632501 NCBI chr 3:111,877,853...111,941,841
Ensembl chr 3:111,877,853...111,941,841
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO (PMID:16542649) RGD PMID:16542649 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snx5 sorting nexin 5 ISO
IBA
ISS
(PMID:18854019)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:18854019, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:138,378,032...138,397,944
Ensembl chr 3:138,378,202...138,397,870
JBrowse link
macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 ISO (PMID:19846667) RGD PMID:19846667 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:18003703 RGD:9685165 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Dock2 dedicator of cytokinesis 2 ISO (MGI:MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:MGI:5291858 NCBI chr10:19,181,512...19,603,171 JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 ISO (MGI:MGI:3761050|PMID:17906627) RGD PMID:17906627 MGI:MGI:3761050 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO
ISS
(MGI:MGI:3761050|PMID:17906627)
GO_REF:0000024
RGD
UniProt
PMID:17906627 GO_REF:0000024, MGI:MGI:3761050 NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954
JBrowse link
G Pycard PYD and CARD domain containing ISO (MGI:MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:MGI:5291858 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rab34 RAB34, member RAS oncogene family NOT ISO (PMID:17881736) RGD PMID:17881736 NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177
JBrowse link
G Snx33 sorting nexin 33 ISO (PMID:21048941) RGD PMID:21048941 NCBI chr 8:61,584,656...61,596,055
Ensembl chr 8:61,584,656...61,595,032
JBrowse link
negative regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stx1b syntaxin 1B ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
negative regulation of pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
(PMID:23583380)
Ensembl
RGD
PMID:23583380 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO (PMID:17693624) RGD PMID:17693624 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Prom2 prominin 2 IEA
ISO
GO_REF:0000107
(PMID:23583380)
Ensembl
RGD
PMID:23583380 GO_REF:0000107 NCBI chr 3:120,087,633...120,107,495
Ensembl chr 3:120,092,582...120,106,697
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:9045618 RGD:11568652 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
positive regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 ISO (MGI:MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:MGI:6270783 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (MGI:MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:MGI:6270783 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
positive regulation of pinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 ISO (MGI:MGI:3687817|PMID:10954430) RGD PMID:10954430 MGI:MGI:3687817 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Ankfy1 ankyrin repeat and FYVE domain containing 1 ISO (PMID:15328530) RGD PMID:15328530 NCBI chr10:59,259,955...59,331,669
Ensembl chr10:59,259,955...59,331,669
JBrowse link
G Axl Axl receptor tyrosine kinase ISO (PMID:21047970) RGD PMID:21047970 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Cdc42 cell division cycle 42 ISS
ISO
GO_REF:0000024
(MGI:MGI:5607692|PMID:24792215)
UniProt
RGD
PMID:24792215 GO_REF:0000024, MGI:MGI:5607692 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:5607692|PMID:24792215) RGD PMID:24792215 MGI:MGI:5607692 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO
ISS
(PMID:16542649)
PMID:8895569
RGD PMID:16542649, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      vesicle-mediated transport 1652
        endocytosis 677
          pinocytosis 25
            macropinocytosis + 11
            micropinocytosis + 0
            negative regulation of pinocytosis + 6
            positive regulation of pinocytosis + 8
            regulation of pinocytosis + 14
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          vesicle-mediated transport 1652
            endocytosis 677
              pinocytosis 25
                macropinocytosis + 11
                micropinocytosis + 0
                negative regulation of pinocytosis + 6
                positive regulation of pinocytosis + 8
                regulation of pinocytosis + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.