pinocytosis - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS	{{ watchLinkText }}

Term:	pinocytosis	go back to main search page
Accession:	GO:0006907	browse the term
Definition:	An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
Synonyms:	exact_synonym:	fluid-phase endocytosis
	narrow_synonym:	clathrin-independent pinocytosis
	related_synonym:	single-organism pinocytosis
	alt_id:	GO:0006908; GO:1902536
	xref:	Wikipedia:Pinocytosis

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Rat (25) Mouse (24) Human (26) Chinchilla (23) Bonobo (24) Dog (24) Squirrel (24) Pig (25) All
Genes (25)

pinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dab2

DAB adaptor protein 2

ISO

MGI:MGI:2387168 (MGI:MGI:3610714|PMID:16263760)

RGD

PMID:16263760

MGI:MGI:3610714

NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270

Ehd4

EH-domain containing 4

IMP

RGD

PMID:12011113

RGD:632501

NCBI chr 3:111,877,853...111,941,841
Ensembl chr 3:111,877,853...111,941,841

Ppt1

palmitoyl-protein thioesterase 1

ISO

(PMID:16542649)

RGD

PMID:16542649

NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162

Snx5

sorting nexin 5

ISO
IBA
ISS

(PMID:18854019)
PMID:21873635
GO_REF:0000024

RGD
UniProt

PMID:18854019, PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 3:138,378,032...138,397,944
Ensembl chr 3:138,378,202...138,397,870

macropinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Carmil1

capping protein regulator and myosin 1 linker 1

ISO

(PMID:19846667)

RGD

PMID:19846667

NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403

dynamin 2

RGD

NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524

Dock2

dedicator of cytokinesis 2

ISO

(MGI:MGI:5291858|PMID:21892172)

RGD

PMID:21892172

MGI:MGI:5291858

NCBI chr10:19,181,512...19,603,171

Mapkapk2

MAPK activated protein kinase 2

ISO

(MGI:MGI:3761050|PMID:17906627)

RGD

PMID:17906627

MGI:MGI:3761050

NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110

Mapkapk3

MAPK activated protein kinase 3

ISO
ISS

(MGI:MGI:3761050|PMID:17906627)
GO_REF:0000024

RGD
UniProt

PMID:17906627

GO_REF:0000024, MGI:MGI:3761050

NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954

Pycard

PYD and CARD domain containing

ISO

(MGI:MGI:5291858|PMID:21892172)

RGD

PMID:21892172

MGI:MGI:5291858

NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210

Rab34

RAB34, member RAS oncogene family

NOT

ISO

(PMID:17881736)

RGD

PMID:17881736

NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177

sorting nexin 33

(PMID:21048941)

NCBI chr 8:61,584,656...61,596,055
Ensembl chr 8:61,584,656...61,595,032

negative regulation of macropinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Stx1b

syntaxin 1B

ISS

GO_REF:0000024

ParkinsonsUK-UCL

GO_REF:0000024

NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627

negative regulation of pinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cav1

caveolin 1

IEA
ISO

GO_REF:0000107
(PMID:23583380)

Ensembl
RGD

PMID:23583380

GO_REF:0000107

NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200

Nr1h2

nuclear receptor subfamily 1, group H, member 2

ISO

(PMID:17693624)

RGD

PMID:17693624

NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942

Nr1h3

nuclear receptor subfamily 1, group H, member 3

ISO

(PMID:17693624)

RGD

PMID:17693624

NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750

Prom2

prominin 2

IEA
ISO

GO_REF:0000107
(PMID:23583380)

Ensembl
RGD

PMID:23583380

GO_REF:0000107

NCBI chr 3:120,087,633...120,107,495
Ensembl chr 3:120,092,582...120,106,697

Tsc2

TSC complex subunit 2

IMP

RGD

PMID:9045618

RGD:11568652

NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584

positive regulation of macropinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Appl1

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

ISO

(MGI:MGI:6270783|PMID:27219021)

RGD

PMID:27219021

MGI:MGI:6270783

NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103

Appl2

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

ISO

(MGI:MGI:6270783|PMID:27219021)

RGD

PMID:27219021

MGI:MGI:6270783

NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126

positive regulation of pinocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Actn4

actinin alpha 4

ISO

(MGI:MGI:3687817|PMID:10954430)

RGD

PMID:10954430

MGI:MGI:3687817

NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333

Ankfy1

ankyrin repeat and FYVE domain containing 1

ISO

(PMID:15328530)

RGD

PMID:15328530

NCBI chr10:59,259,955...59,331,669
Ensembl chr10:59,259,955...59,331,669

Axl

Axl receptor tyrosine kinase

ISO

(PMID:21047970)

RGD

PMID:21047970

NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761

Cdc42

cell division cycle 42

ISS
ISO

GO_REF:0000024
(MGI:MGI:5607692|PMID:24792215)

UniProt
RGD

PMID:24792215

GO_REF:0000024, MGI:MGI:5607692

NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300

Cln3

CLN3 lysosomal/endosomal transmembrane protein, battenin

ISO

(MGI:MGI:5607692|PMID:24792215)

RGD

PMID:24792215

MGI:MGI:5607692

NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664

Ppt1

palmitoyl-protein thioesterase 1

ISO
ISS

(PMID:16542649)
PMID:8895569

RGD

PMID:16542649, PMID:8895569

RGD:8553248

NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162

Term paths to the root

Path 1
Term	Annotations
biological_process	20014
cellular process	18788
vesicle-mediated transport	1652
endocytosis	677
pinocytosis	25
macropinocytosis +	11
micropinocytosis +	0
negative regulation of pinocytosis +	6
positive regulation of pinocytosis +	8
regulation of pinocytosis +	14
Path 2
Term	Annotations
biological_process	20014
localization	6486
establishment of localization	4918
transport	4774
vesicle-mediated transport	1652
endocytosis	677
pinocytosis	25
macropinocytosis +	11
micropinocytosis +	0
negative regulation of pinocytosis +	6
positive regulation of pinocytosis +	8
regulation of pinocytosis +	14

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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ONTOLOGY REPORT - ANNOTATIONS