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ONTOLOGY REPORT - ANNOTATIONS


Term:receptor-mediated endocytosis
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Accession:GO:0006898 term browser browse the term
Definition:An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
Synonyms:xref: Wikipedia:Receptor-mediated_endocytosis


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receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1624291
RGD:1600115
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:1624291
G Amn amnion associated transmembrane protein JBrowse link 6 135,724,455 135,731,896 RGD:1624291
RGD:13792537
G Ap1g2 adaptor related protein complex 1 subunit gamma 2 JBrowse link 15 33,759,108 33,767,017 RGD:13792537
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 1 100,896,582 100,926,443 RGD:13792537
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 JBrowse link 1 214,534,217 214,607,497 RGD:13792537
G Ap4e1 adaptor related protein complex 4 subunit epsilon 1 JBrowse link 3 119,484,714 119,548,491 RGD:13792537
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
G Arhgap27 Rho GTPase activating protein 27 JBrowse link 10 91,418,535 91,451,831 RGD:1302833
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:629531
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 JBrowse link 5 140,559,195 140,585,494 RGD:1624291
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:1624291
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:13825436
RGD:1624291
G Clec9a C-type lectin domain containing 9A JBrowse link 4 163,173,593 163,189,532 RGD:1624291
RGD:13792537
RGD:1600115
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
RGD:1600115
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:8553642
RGD:13792537
RGD:1624291
G Cttn cortactin JBrowse link 1
1
217,602,698
215,255,385
217,638,196
215,290,882
RGD:727733
RGD:10047197
G Cubn cubilin JBrowse link 17 80,584,921 80,807,181 RGD:628443
RGD:1600115
RGD:1624291
RGD:8554807
G Cxcl16 C-X-C motif chemokine ligand 16 JBrowse link 10 57,060,005 57,064,600 RGD:1600115
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1624291
RGD:13792537
G Dbnl drebrin-like JBrowse link 14 86,029,335 86,044,364 RGD:1600115
G Dmbt1 deleted in malignant brain tumors 1 JBrowse link 1
1
201,620,642
203,149,414
201,689,905
203,228,705
RGD:1624291
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 8 112,697,907 112,830,445 RGD:13792537
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 5 120,330,372 120,492,515 RGD:13792537
G Dnm1 dynamin 1 JBrowse link 3 11,338,081 11,382,043 RGD:727371
RGD:1624291
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:728683
RGD:10047197
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:9588617
RGD:1624291
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:12910993
G Gak cyclin G associated kinase JBrowse link 14 2,100,104 2,174,332 RGD:1624291
RGD:13792537
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1624291
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link 5 155,812,096 155,913,751 RGD:1624291
G Ifitm3 interferon induced transmembrane protein 3 JBrowse link 1 213,810,712 213,811,821 RGD:1624291
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:13210538
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:1624291
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 JBrowse link 3 91,596,730 91,839,054 RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
G Lmbr1l limb development membrane protein 1-like JBrowse link 7 140,585,512 140,600,797 RGD:1624291
RGD:13792537
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800558
RGD:8554276
RGD:1624291
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:628443
RGD:1600115
RGD:1624291
RGD:13210547
RGD:13210545
RGD:13210554
RGD:13210549
RGD:13210565
RGD:13210553
RGD:13210531
RGD:13210530
RGD:13210557
RGD:1299150
RGD:8554276
G Marco macrophage receptor with collagenous structure JBrowse link 16 85,115,199 85,147,683 RGD:13432286
G Micall1 MICAL-like 1 JBrowse link 7 120,343,900 120,375,151 RGD:1624291
RGD:1600115
G Mrc1 mannose receptor, C type 1 JBrowse link 17 81,352,700 81,433,743 RGD:1624291
RGD:13792537
G Msr1 macrophage scavenger receptor 1 JBrowse link 16 56,817,714 56,900,025 RGD:1624291
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:8554205
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1624291
RGD:1600115
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing JBrowse link 9 71,911,744 72,005,816 RGD:1624291
G Pla2r1 phospholipase A2 receptor 1 JBrowse link 3 46,488,963 46,621,873 RGD:1624291
RGD:1600115
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:1624291
G Ppt1 palmitoyl-protein thioesterase 1 JBrowse link 5 140,538,260 140,558,163 RGD:1624291
RGD:13792537
G Reps1 RALBP1 associated Eps domain containing 1 JBrowse link 1 13,262,049 13,298,347 RGD:1600115
G Scarb2 scavenger receptor class B, member 2 JBrowse link 14 17,064,173 17,115,620 RGD:1624291
G Scarf1 scavenger receptor class F, member 1 JBrowse link 10 63,662,967 63,683,916 RGD:1600115
G Slc9a3 solute carrier family 9 member A3 JBrowse link 1 31,731,652 31,777,144 RGD:1581379
G Snx17 sorting nexin 17 JBrowse link 6 26,541,137 26,546,650 RGD:1624291
RGD:1600115
G Snx9 sorting nexin 9 JBrowse link 1 46,780,142 46,826,250 RGD:1624291
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:1624291
G Tfr2 transferrin receptor 2 JBrowse link 12 22,177,382 22,194,330 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1579921
G Tmem108 transmembrane protein 108 JBrowse link 8 111,968,568 112,265,623 RGD:1624291
RGD:1600115
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:1624291
RGD:1600115
G Wasf1 WASP family member 1 JBrowse link 20 48,456,191 48,503,768 RGD:1624291
RGD:1600115
clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 1 100,896,582 100,926,443 RGD:1624291
RGD:13792537
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 JBrowse link 1 214,534,217 214,607,497 RGD:1600115
RGD:1624291
RGD:13792537
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:1624291
RGD:13792537
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 JBrowse link 1 78,671,238 78,682,847 RGD:1600115
G Canx calnexin JBrowse link 10 35,800,942 35,833,939 RGD:1624291
RGD:1600115
G Clta clathrin, light chain A JBrowse link 5 59,490,689 59,509,139 RGD:13792537
G Cltb clathrin, light chain B JBrowse link 17 10,537,348 10,554,999 RGD:13792537
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:10402035
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 5 120,330,372 120,492,515 RGD:13792537
G Fcho1 FCH and mu domain containing endocytic adaptor 1 JBrowse link 16 20,136,008 20,153,344 RGD:1624291
RGD:13792537
G Fcho2 FCH and mu domain containing endocytic adaptor 2 JBrowse link 2 28,927,918 29,029,271 RGD:1600115
RGD:13792537
RGD:1624291
G Fchsd2 FCH and double SH3 domains 2 JBrowse link 1 166,140,025 166,395,915 RGD:1624291
G Fnbp1l formin binding protein 1-like JBrowse link 2 226,691,435 226,742,081 RGD:1624291
G Gak cyclin G associated kinase JBrowse link 14 2,100,104 2,174,332 RGD:1600115
RGD:13792537
RGD:1624291
G Gpr107 G protein-coupled receptor 107 JBrowse link 3 10,632,876 10,694,654 RGD:1624291
RGD:13792537
G Hip1 huntingtin interacting protein 1 JBrowse link 12 24,180,795 24,315,373 RGD:1600115
G Inpp5f inositol polyphosphate-5-phosphatase F JBrowse link 1 200,037,749 200,116,524 RGD:1624291
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1624291
RGD:13792537
RGD:1600115
G Sgip1 SH3GL interacting endocytic adaptor 1 JBrowse link 5 122,300,415 122,498,478 RGD:1600115
RGD:13792537
G Siglec1 sialic acid binding Ig like lectin 1 JBrowse link 3 123,612,067 123,631,718 RGD:1624291
G Slc9b2 solute carrier family 9 member B2 JBrowse link 2 240,485,254 240,519,166 RGD:1624291
G Snap91 synaptosome associated protein 91 JBrowse link 8 94,447,558 94,564,772 RGD:13792537
clathrin-dependent endocytosis of virus by host cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Siglec1 sialic acid binding Ig like lectin 1 JBrowse link 3 123,612,067 123,631,718 RGD:1624291
RGD:13792537
clathrin-dependent extracellular exosome endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itga4 integrin subunit alpha 4 JBrowse link 3 66,178,745 66,265,547 RGD:9698434
clathrin-dependent synaptic vesicle endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btbd8 BTB domain containing 8 JBrowse link 14 3,282,422 3,351,740 RGD:1600115
RGD:1624291
G Itsn1 intersectin 1 JBrowse link 11 31,943,119 32,069,249 RGD:13792537
G Itsn2 intersectin 2 JBrowse link 6 30,098,378 30,208,694 RGD:13792537
endocytic hemoglobin import into cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cubn cubilin JBrowse link 17 80,584,921 80,807,181 RGD:2317837
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:2317837
endocytic iron import into cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tfr2 transferrin receptor 2 JBrowse link 12 22,177,382 22,194,330 RGD:1624291
RGD:13792537
G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Arr3 arrestin 3 JBrowse link X 70,438,590 70,452,140 RGD:13792537
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:13792537
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
RGD:13792537
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
G Dnm1 dynamin 1 JBrowse link 3 11,338,081 11,382,043 RGD:9685157
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:9685157
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1581465
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:1581465
RGD:1624291
G Grk4 G protein-coupled receptor kinase 4 JBrowse link 14 81,261,708 81,339,516 RGD:1304268
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:1624291
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:1624291
G Sag S-antigen visual arrestin JBrowse link 9 94,926,901 94,972,162 RGD:13792537
insulin receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:11059580
RGD:11059573
G Lmbrd1 LMBR1 domain containing 1 JBrowse link 9 30,939,555 31,038,381 RGD:1624291
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 JBrowse link 1 144,069,641 144,200,402 RGD:13504745
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:11079192
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
G Unc119 unc-119 lipid binding chaperone JBrowse link 10 65,606,919 65,612,324 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Necab2 N-terminal EF-hand calcium binding protein 2 JBrowse link 19 52,086,325 52,112,633 RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
negative regulation of receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd13a ankyrin repeat domain 13a JBrowse link 12 47,558,587 47,588,486 RGD:1624291
G Ankrd13b ankyrin repeat domain 13B JBrowse link 10 62,674,416 62,691,949 RGD:1624291
G Ankrd13d ankyrin repeat domain 13D JBrowse link 1 219,520,316 219,532,718 RGD:1624291
G Atxn2 ataxin 2 JBrowse link 12 40,264,601 40,335,637 RGD:1624291
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554437
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:12050150
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:1624291
RGD:13792537
G LRRTM1 leucine rich repeat transmembrane neuronal 1 JBrowse link 4 108,300,927 108,316,373 RGD:1624291
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 JBrowse link 18 28,012,877 28,017,925 RGD:1624291
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
G Sdcbp syndecan binding protein JBrowse link 5 19,471,664 19,498,499 RGD:1624291
RGD:1600115
G Wdr54 WD repeat domain 54 JBrowse link 4 114,847,722 114,871,989 RGD:1624291
negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoc1 apolipoprotein C1 JBrowse link 1 80,606,638 80,609,921 RGD:1624291
G Apoc2 apolipoprotein C2 JBrowse link 1 80,589,023 80,593,991 RGD:1624291
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1624291
RGD:1600115
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1624291
RGD:1600115
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:1600115
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
neurotransmitter receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:1624291
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 JBrowse link 7 119,228,112 119,353,332 RGD:1624291
RGD:13792537
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 JBrowse link 1 192,613,766 192,708,371 RGD:13792537
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:13792537
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 JBrowse link 10 96,122,240 96,166,606 RGD:13792537
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 JBrowse link 1 64,374,547 64,405,380 RGD:13792537
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 JBrowse link 1 64,330,106 64,350,338 RGD:13792537
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:1624291
RGD:1600115
positive regulation of clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1600115
RGD:1624291
G Dgkd diacylglycerol kinase, delta JBrowse link 9 94,980,328 95,071,531 RGD:1624291
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:728683
G Scyl2 SCY1 like pseudokinase 2 JBrowse link 7 30,291,087 30,344,464 RGD:1624291
G Wasl WASP like actin nucleation promoting factor JBrowse link 4 51,677,722 51,726,212 RGD:8554834
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apln apelin JBrowse link X 134,856,719 134,866,210 RGD:12907555
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
positive regulation of receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahi1 Abelson helper integration site 1 JBrowse link 1 16,478,127 16,601,769 RGD:1624291
RGD:1600115
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1600115
RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:13461854
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:5510008
RGD:1624291
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 1 251,234,702 251,386,996 RGD:1624291
RGD:1600115
G Cd63 Cd63 molecule JBrowse link 7 3,320,250 3,335,583 RGD:1600115
RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1624291
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:2311559
G Dtnbp1 dystrobrevin binding protein 1 JBrowse link 17 20,090,136 20,182,332 RGD:8553895
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
RGD:1624291
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1600115
RGD:1624291
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:1600115
RGD:1624291
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:1624291
RGD:1600115
G Pard3 par-3 family cell polarity regulator JBrowse link 19 60,017,746 60,580,628 RGD:1624291
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:8554748
RGD:13792537
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1624291
RGD:1600115
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 JBrowse link 1 103,197,918 103,258,309 RGD:9835004
G Scyl2 SCY1 like pseudokinase 2 JBrowse link 7 30,291,087 30,344,464 RGD:1624291
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:1624291
RGD:1600115
G Sfrp4 secreted frizzled-related protein 4 JBrowse link 17 47,383,983 47,394,065 RGD:1624291
RGD:1600115
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Synj2bp synaptojanin 2 binding protein JBrowse link 6 105,224,166 105,261,549 RGD:1624291
G Tbc1d5 TBC1 domain family, member 5 JBrowse link 9 1,144,641 1,747,732 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
positive regulation of receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 1 100,896,582 100,926,443 RGD:13452389
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Bicd1 BICD cargo adaptor 1 JBrowse link 4 184,018,845 184,167,628 RGD:1624291
RGD:13792537
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1600115
RGD:1624291
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:1624291
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1600115
RGD:1624291
G H1f1 H1.1 linker histone, cluster member JBrowse link 17 43,614,101 43,614,844 RGD:1624291
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1624291
G Hip1 huntingtin interacting protein 1 JBrowse link 12 24,180,795 24,315,373 RGD:1624291
RGD:13792537
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:13792537
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:13825436
RGD:13792537
RGD:1624291
G Kif3a kinesin family member 3a JBrowse link 10 38,918,705 38,953,958 RGD:1581596
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:2299909
G Ppt1 palmitoyl-protein thioesterase 1 JBrowse link 5 140,538,260 140,558,163 RGD:1624291
RGD:8553248
G Rab21 RAB21, member RAS oncogene family JBrowse link 7 58,261,985 58,286,770 RGD:1624291
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:1600115
RGD:8554276
G Sgip1 SH3GL interacting endocytic adaptor 1 JBrowse link 5 122,300,415 122,498,478 RGD:1624291
RGD:8554282
RGD:1600115
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:2314546
G Synj1 synaptojanin 1 JBrowse link 11 31,105,784 31,181,573 RGD:2312450
G Tf transferrin JBrowse link 8 111,694,570 111,721,275 RGD:1624291
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:1624291
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:13432317
RGD:1624291
G Caly calcyon neuron-specific vesicular protein JBrowse link 1 212,537,851 212,549,040 RGD:1624291
G Dnm1 dynamin 1 JBrowse link 3 11,338,081 11,382,043 RGD:13792537
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:13792537
G Dnm3 dynamin 3 JBrowse link 13 79,906,711 80,379,967 RGD:8553820
RGD:13792537
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 5 128,923,809 129,022,268 RGD:13702241
G Mx1 myxovirus (influenza virus) resistance 1 JBrowse link 11 37,891,150 37,916,775 RGD:13792537
G Mx2 MX dynamin like GTPase 2 JBrowse link 11 38,035,306 38,066,185 RGD:13792537
G Myo6 myosin VI JBrowse link 8 87,583,649 87,731,271 RGD:1624291
G Synj1 synaptojanin 1 JBrowse link 11 31,105,784 31,181,573 RGD:1624291
prostaglandin receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043344
receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:1624291
RGD:1600115
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:1600115
RGD:1624291
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:1624291
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
G Calcrl calcitonin receptor like receptor JBrowse link 3 71,747,938 71,845,487 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
RGD:1600115
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Cd9 CD9 molecule JBrowse link 4 157,977,163 158,010,091 RGD:1624291
RGD:1600115
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:1624291
G Cntn2 contactin 2 JBrowse link 13 49,280,913 49,314,061 RGD:1624291
RGD:1600115
G Cxcr1 C-X-C motif chemokine receptor 1 JBrowse link 9 81,466,430 81,469,299 RGD:1624291
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:1624291
G Dnm1 dynamin 1 JBrowse link 3 11,338,081 11,382,043 RGD:8554168
RGD:13792537
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:1624291
RGD:13792537
G Dnm3 dynamin 3 JBrowse link 13 79,906,711 80,379,967 RGD:13792537
G Ezr ezrin JBrowse link 1 47,287,872 47,331,412 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:1600115
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:1624291
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:1624291
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:8554168
RGD:1624291
RGD:1600115
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:8554168
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:1600115
RGD:1624291
G Grk3 G protein-coupled receptor kinase 3 JBrowse link 12 49,626,871 49,750,389 RGD:1600115
RGD:1624291
G Grk4 G protein-coupled receptor kinase 4 JBrowse link 14 81,261,708 81,339,516 RGD:1624291
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1600115
RGD:1624291
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
G Mx1 myxovirus (influenza virus) resistance 1 JBrowse link 11 37,891,150 37,916,775 RGD:13792537
G Mx2 MX dynamin like GTPase 2 JBrowse link 11 38,035,306 38,066,185 RGD:13792537
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link 8 79,323,408 79,408,842 RGD:1600115
RGD:13792537
RGD:1624291
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1600115
RGD:1624291
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043344
G Rab31 RAB31, member RAS oncogene family JBrowse link 9 113,370,072 113,504,606 RGD:1600115
RGD:1624291
G Ramp1 receptor activity modifying protein 1 JBrowse link 9 98,313,632 98,364,206 RGD:8554018
RGD:13792537
RGD:1624291
G Ramp2 receptor activity modifying protein 2 JBrowse link 10 89,166,170 89,168,962 RGD:8554018
RGD:13792537
RGD:1624291
G Ramp3 receptor activity modifying protein 3 JBrowse link 14 86,922,223 86,939,722 RGD:1624291
RGD:13792537
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
G Snx1 sorting nexin 1 JBrowse link 8 71,745,687 71,786,182 RGD:1624291
RGD:1600115
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:1624291
RGD:1600115
G Ulk1 unc-51 like autophagy activating kinase 1 JBrowse link 12 51,908,105 51,934,704 RGD:1624291
receptor internalization involved in canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Rab5a RAB5A, member RAS oncogene family JBrowse link 9 5,910 6,065 RGD:1624291
G Scyl2 SCY1 like pseudokinase 2 JBrowse link 7 30,291,087 30,344,464 RGD:1624291
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
receptor-mediated endocytosis of virus by host cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:1624291
RGD:1600115
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:1624291
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 5 128,923,809 129,022,268 RGD:1624291
G LOC100294508 dyslexia susceptibility 2-like JBrowse link 5 144,779,306 144,872,271 RGD:1624291
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing JBrowse link 9 71,911,744 72,005,816 RGD:1624291
G Tpcn2 two pore segment channel 2 JBrowse link 1 218,419,182 218,448,902 RGD:1624291
regulation of clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aak1 AP2 associated kinase 1 JBrowse link 4 118,653,851 118,806,796 RGD:8553925
RGD:13792537
RGD:1624291
RGD:1600115
G Bmp2k BMP-2 inducible kinase JBrowse link 14 14,126,086 14,226,823 RGD:13792537
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 5 120,330,372 120,492,515 RGD:1624291
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1600115
G Prom2 prominin 2 JBrowse link 3 120,087,633 120,107,495 RGD:1624291
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 JBrowse link 5 103,479,767 103,654,507 RGD:13504745
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 JBrowse link 1 144,069,641 144,200,402 RGD:13504745
G Smap1 small ArfGAP 1 JBrowse link 9 30,068,888 30,161,753 RGD:1624291
RGD:13792537
G Snap91 synaptosome associated protein 91 JBrowse link 8 94,447,558 94,564,772 RGD:1624291
RGD:1600115
G Tnk2 tyrosine kinase, non-receptor, 2 JBrowse link 11 71,348,726 71,388,520 RGD:1624291
regulation of postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:2313185
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:1624291
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 1 251,234,702 251,386,996 RGD:1624291
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:13702467
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:1600115
RGD:1624291
G Efnb2 ephrin B2 JBrowse link 16 86,631,151 86,672,050 RGD:1624291
G Gsg1l GSG1-like JBrowse link 1 197,271,704 197,482,776 RGD:1624291
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:13702182
G Hpca hippocalcin JBrowse link 5 147,295,124 147,305,757 RGD:13702412
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 JBrowse link 4 123,400,717 123,454,656 RGD:1624291
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:1624291
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link 8 79,323,408 79,408,842 RGD:13702142
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1600115
RGD:1624291
G Ophn1 oligophrenin 1 JBrowse link X 68,185,865 68,579,518 RGD:1624291
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 JBrowse link 20 7,241,248 7,286,702 RGD:13702454
RGD:13702399
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:13702248
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma JBrowse link 7 11,267,207 11,294,291 RGD:1624291
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:12050130
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:13702139
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209020
G Synj1 synaptojanin 1 JBrowse link 11 31,105,784 31,181,573 RGD:1624291
G Usp46 ubiquitin specific peptidase 46 JBrowse link 14 36,687,134 36,755,360 RGD:11056935
regulation of receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:8553918
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Flot1 flotillin 1 JBrowse link 20 3,427,890 3,438,418 RGD:1624291
G Mkln1 muskelin 1 JBrowse link 4 58,693,384 58,817,924 RGD:13702173
G Napb NSF attachment protein beta JBrowse link 3 143,017,571 143,063,904 RGD:633462
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 10 91,879,608 91,986,242 RGD:633462
G Rspo1 R-spondin 1 JBrowse link 5 142,986,526 143,007,847 RGD:1624291
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 JBrowse link 5 103,479,767 103,654,507 RGD:1624291
G Synj2bp synaptojanin 2 binding protein JBrowse link 6 105,224,166 105,261,549 RGD:1624291
regulation of receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd2ap CD2-associated protein JBrowse link 9 20,794,680 20,858,438 RGD:1302417
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:1624291
RGD:13792537
RGD:1600115
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1601478
regulation of signal transduction by receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      vesicle-mediated transport 1651
        endocytosis 670
          receptor-mediated endocytosis 250
            clathrin-dependent endocytosis + 44
            endocytic heme import into cell + 2
            endocytic iron import into cell 1
            negative regulation of receptor-mediated endocytosis + 24
            positive regulation of receptor-mediated endocytosis + 61
            receptor internalization + 136
            receptor-mediated endocytosis involved in cholesterol transport + 6
            receptor-mediated endocytosis of virus by host cell + 8
            regulation of receptor-mediated endocytosis + 120
Path 2
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      establishment of localization 4905
        transport 4762
          vesicle-mediated transport 1651
            endocytosis 670
              receptor-mediated endocytosis 250
                clathrin-dependent endocytosis + 44
                endocytic heme import into cell + 2
                endocytic iron import into cell 1
                negative regulation of receptor-mediated endocytosis + 24
                positive regulation of receptor-mediated endocytosis + 61
                receptor internalization + 136
                receptor-mediated endocytosis involved in cholesterol transport + 6
                receptor-mediated endocytosis of virus by host cell + 8
                regulation of receptor-mediated endocytosis + 120
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.