Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:serotonin transport
go back to main search page
Accession:GO:0006837 term browser browse the term
Definition:The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.


show annotations for term's descendants           Sort by:
 
serotonin transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 involved_in IMP (MGI:3805626|PMID:18513366) ARUK-UCL PMID:18513366 MGI:3805626 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591 		JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 involved_in IMP
ISO		 (MGI:4820706|PMID:19308295) UniProt
MGI
RGD		 PMID:15994310 PMID:19308295 GO_REF:0000096 MGI:4417868 MGI:4820706 RGD:1580635 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166 		JBrowse link
negative regulation of serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300A molecule acts_upstream_of_or_within IDA (MGI:3721168|PMID:12874256) MGI PMID:12874256 MGI:3721168 NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480 		JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI
RGD		 PMID:15470136 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:1626430 NCBI chr 2:179,741,258...179,746,293
Ensembl chr 2:179,741,258...179,746,281 		JBrowse link
G Htr1b 5-hydroxytryptamine (serotonin) receptor 1B involved_in IMP (MGI:1098377|PMID:9349547) UniProt PMID:9349547 MGI:1098377 NCBI chr 9:81,510,344...81,515,885
Ensembl chr 9:81,510,344...81,515,881 		JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 ISO RGD PMID:15260125 RGD:6480684 NCBI chr19:35,935,815...36,035,533
Ensembl chr19:35,936,134...36,034,907 		JBrowse link
G Maob monoamine oxidase B involved_in ISO RGD
MGI		 PMID:12175458 GO_REF:0000096 MGI:4417868 RGD:2316765 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605 		JBrowse link
negative regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpm6b glycoprotein m6b involved_in IDA
IBA		 (MGI:5426133|PMID:18581270)
(MGI:6201960|PMID:21873635)		 UniProt
GO_Central		 PMID:18581270 PMID:21873635 MGI:5426133 MGI:6201960 NCBI chr  X:165,021,775...165,172,029
Ensembl chr  X:165,021,907...165,171,984 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal involved_in IDA (MGI:3710710|PMID:17452640) UniProt PMID:17452640 MGI:3710710 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Slc18a1 solute carrier family 18 (vesicular monoamine), member 1 involved_in ISO G-protein mediated uptake inhibition RGD
MGI		 PMID:16926160 GO_REF:0000096 MGI:4417868 RGD:5130998 NCBI chr 8:69,490,360...69,547,951
Ensembl chr 8:69,490,363...69,541,887 		JBrowse link
G Snca synuclein, alpha involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839 		JBrowse link
positive regulation of serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 involved_in ISO RGD
MGI		 PMID:20655906 GO_REF:0000096 MGI:4417868 RGD:5130946 NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 involved_in ISO RGD
MGI		 PMID:8347574 GO_REF:0000096 MGI:4417868 RGD:9685207 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 involved_in ISO RGD
MGI		 PMID:25261262 GO_REF:0000096 MGI:4417868 RGD:11532763 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166 		JBrowse link
regulation of serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone involved_in ISO RGD
MGI		 PMID:21947356 GO_REF:0000096 MGI:4417868 RGD:5507821 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A involved_in IMP (MGI:1314969|PMID:9826725) UniProt PMID:9826725 MGI:1314969 NCBI chr13:105,580,201...105,584,641
Ensembl chr13:105,580,147...105,584,630 		JBrowse link
regulation of serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fev FEV transcription factor, ETS family member involved_in NAS (MGI:5816438|PMID:25642596) ParkinsonsUK-UCL PMID:25642596 MGI:5816438 NCBI chr 1:74,920,660...74,924,632
Ensembl chr 1:74,920,668...74,924,578 		JBrowse link
G Itgb3 integrin beta 3 involved_in IMP (MGI:6101340|PMID:29038237) UniProt PMID:29038237 MGI:6101340 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
serotonin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300A molecule acts_upstream_of IDA (MGI:3721168|PMID:12874256) MGI PMID:12874256 MGI:3721168 NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480 		JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide acts_upstream_of_or_within IMP
IDA		 (MGI:86632|PMID:8252632)
(MGI:85068|PMID:9000133)		 MGI PMID:8252632 PMID:9000133 MGI:85068 MGI:86632 NCBI chr 1:173,048,836...173,054,799
Ensembl chr 1:173,048,851...173,054,781 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III acts_upstream_of_or_within IDA (MGI:78617|PMID:8552190) MGI PMID:8552190 MGI:78617 NCBI chr 1:170,878,738...170,893,476
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) acts_upstream_of_or_within IDA (MGI:78617|PMID:8552190), (MGI:85068|PMID:9000133) MGI PMID:8552190 PMID:9000133 MGI:78617 MGI:85068
G Syk spleen tyrosine kinase acts_upstream_of_or_within IMP (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300A molecule acts_upstream_of_or_within IDA (MGI:3721168|PMID:12874256) MGI PMID:12874256 MGI:3721168 NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480 		JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide involved_in IMP (MGI:87668|PMID:9171347) UniProt PMID:9171347 MGI:87668 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G P2rx1 purinergic receptor P2X, ligand-gated ion channel, 1 acts_upstream_of_or_within IMP (MGI:2671726|PMID:12913094) MGI PMID:12913094 MGI:2671726 NCBI chr11:72,889,882...72,906,026
Ensembl chr11:72,889,929...72,906,026 		JBrowse link
G Syk spleen tyrosine kinase involved_in IMP (MGI:87668|PMID:9171347) UniProt PMID:9171347 MGI:87668 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
serotonin secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xbp1 X-box binding protein 1 involved_in ISO RGD
MGI		 PMID:16889758 GO_REF:0000096 MGI:4417868 RGD:2326003 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893 		JBrowse link
serotonin uptake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 (vesicular monoamine), member 1 involved_in ISO RGD
MGI		 PMID:19008227 GO_REF:0000096 MGI:4417868 RGD:5131091 NCBI chr 8:69,490,360...69,547,951
Ensembl chr 8:69,490,363...69,541,887 		JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 involved_in ISO RGD
MGI		 PMID:20007701 GO_REF:0000096 MGI:4417868 RGD:5130957 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591 		JBrowse link
G Slc29a4 solute carrier family 29 (nucleoside transporters), member 4 involved_in IMP
ISO		 (MGI:5484979|PMID:23255610), (MGI:6436398|PMID:20858707) ARUK-UCL
MGI		 PMID:20858707 PMID:23255610 GO_REF:0000096 MGI:4834177 MGI:5484979 MGI:6436398 NCBI chr 5:142,678,124...142,708,245
Ensembl chr 5:142,678,267...142,708,245 		JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 involved_in IDA
ISO
IMP
IBA		 (MGI:3710710|PMID:17452640)
(MGI:2178281|PMID:9547354), (MGI:6436398|PMID:20858707)
(MGI:6201960|PMID:21873635)		 UniProt
MGI
RGD
ARUK-UCL
GO_Central		 PMID:9547354 PMID:12944413 PMID:17452640 PMID:20858707 PMID:21873635 GO_REF:0000096 MGI:2178281 MGI:3710710 MGI:4417868 MGI:4834177 MGI:6201960 MGI:6436398 RGD:1580638 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28749
    localization 5578
      establishment of localization 4931
        transport 4766
          ion transport 1620
            cation transport 1217
              serotonin transport 29
                serotonin secretion + 18
                serotonin uptake + 12
paths to the root