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ONTOLOGY REPORT - ANNOTATIONS

Term:iron ion transport
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Accession:GO:0006826 term browser browse the term
Definition:The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: iron transport
 narrow_synonym: ferric ion import;   ferric ion transport;   ferric iron import;   ferric iron transport;   ferric iron uptake;   ferrous ion transport;   ferrous iron transport
 related_synonym: iron ion import
 alt_id: GO:0015681;   GO:0015682;   GO:0015684;   GO:0033216;   GO:0097286

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iron ion transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:9531620) MGI PMID:9531620 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Fth1 ferritin heavy chain 1 acts_upstream_of_or_within ISO (PMID:21886823) MGI PMID:21886823 NCBI chrNW_004955511:5,772,374...5,773,224
Ensembl chrNW_004955511:5,771,777...5,773,112 		JBrowse link
G LOC102027549 serotransferrin acts_upstream_of_or_within ISO (PMID:11230685) RGD
MGI		 PMID:11230685 PMID:17373738 RGD:1601530 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910 		JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:7556058) UniProt PMID:7556058 NCBI chrNW_004955420:13,036,767...13,055,477
Ensembl chrNW_004955420:13,035,309...13,055,548 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 acts_upstream_of_or_within ISO (PMID:18057121) MGI PMID:18057121 NCBI chrNW_004955489:9,086,494...9,133,374
Ensembl chrNW_004955489:9,086,506...9,096,746 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:18703497) MGI PMID:18703497 NCBI chrNW_004955412:20,683,007...20,745,069
Ensembl chrNW_004955412:20,682,861...20,745,069 		JBrowse link
G Sfxn1 sideroflexin 1 acts_upstream_of_or_within ISO (PMID:11274051) MGI PMID:11274051 NCBI chrNW_004955408:28,054,211...28,105,294
Ensembl chrNW_004955408:28,054,211...28,106,175 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in ISO (PMID:16510578)
(PMID:9730978)		 BHF-UCL
UniProt		 PMID:9730978 PMID:16510578 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 acts_upstream_of_or_within ISO (PMID:16950869) MGI PMID:16950869 NCBI chrNW_004955403:45,828,247...45,867,309
Ensembl chrNW_004955403:45,827,942...45,867,309 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 acts_upstream_of_or_within ISO (PMID:10828623) MGI PMID:10828623 NCBI chrNW_004955403:9,253,734...9,271,732
Ensembl chrNW_004955403:9,253,734...9,271,916 		JBrowse link
G Slc41a2 solute carrier family 41 member 2 involved_in ISO (PMID:15809054) UniProt PMID:15809054 NCBI chrNW_004955405:39,181,396...39,280,789
Ensembl chrNW_004955405:39,178,611...39,280,839 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16227996) MGI PMID:16227996 NCBI chrNW_004955459:10,441,906...10,485,235
Ensembl chrNW_004955459:10,441,752...10,485,269 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:7556058) UniProt PMID:7556058 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
endocytic iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955573:272,315...289,227
Ensembl chrNW_004955573:272,289...291,668 		JBrowse link
heme export term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flvcr1 FLVCR choline and heme transporter 1 involved_in ISO (PMID:15369674) UniProt PMID:15369674 NCBI chrNW_004955406:4,673,797...4,702,858
Ensembl chrNW_004955406:4,674,140...4,702,763 		JBrowse link
G Slc48a1 solute carrier family 48 member 1 involved_in ISO (PMID:23395172) MGI PMID:23395172 NCBI chrNW_004955500:6,675,631...6,691,942
Ensembl chrNW_004955500:6,679,908...6,691,942 		JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc48a1 solute carrier family 48 member 1 involved_in ISO (PMID:31571584) MGI PMID:31571584 NCBI chrNW_004955500:6,675,631...6,691,942
Ensembl chrNW_004955500:6,679,908...6,691,942 		JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in ISO (PMID:33007128) UniProt PMID:33007128 NCBI chrNW_004955453:14,215,104...14,222,338
Ensembl chrNW_004955453:14,215,408...14,222,172 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 involved_in ISO (PMID:24836561) UniProt PMID:24836561 NCBI chrNW_004955420:23,447,920...23,522,732
Ensembl chrNW_004955420:23,447,920...23,522,732 		JBrowse link
heme transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in ISO (PMID:17661442)
(PMID:17006453)		 UniProt PMID:17006453 PMID:17661442 NCBI chrNW_004955453:14,215,104...14,222,338
Ensembl chrNW_004955453:14,215,408...14,222,172 		JBrowse link
G Flvcr1 FLVCR choline and heme transporter 1 acts_upstream_of_or_within ISO (PMID:23187127) MGI PMID:23187127 NCBI chrNW_004955406:4,673,797...4,702,858
Ensembl chrNW_004955406:4,674,140...4,702,763 		JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 involved_in ISO (PMID:31748741) UniProt PMID:31748741 NCBI chrNW_004955428:13,260,915...13,278,656 JBrowse link
G Slc46a1 solute carrier family 46 member 1 involved_in ISO (PMID:16143108) UniProt PMID:16143108 NCBI chrNW_004955481:4,735,325...4,741,810
Ensembl chrNW_004955481:4,734,967...4,745,586 		JBrowse link
G Slc48a1 solute carrier family 48 member 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:18418376)
(PMID:23395172)		 WB
MGI		 PMID:18418376 PMID:23395172 NCBI chrNW_004955500:6,675,631...6,691,942
Ensembl chrNW_004955500:6,679,908...6,691,942 		JBrowse link
iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781) UniProt PMID:20682781 NCBI chrNW_004955403:45,828,247...45,867,309
Ensembl chrNW_004955403:45,827,942...45,867,309 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955459:10,441,906...10,485,235
Ensembl chrNW_004955459:10,441,752...10,485,269 		JBrowse link
G Steap4 STEAP4 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955432:5,618,086...5,641,372
Ensembl chrNW_004955432:5,618,086...5,641,565 		JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004955434:3,983,225...4,008,324
Ensembl chrNW_004955434:3,980,653...4,008,761 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in ISO (PMID:35513392)
(PMID:16511496)		 UniProt PMID:16511496 PMID:35513392 NCBI chrNW_004955403:46,697,560...46,739,082
Ensembl chrNW_004955403:46,697,560...46,739,903 		JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 member 1 involved_in ISO (PMID:15514116), (PMID:30647129) UniProt PMID:15514116 PMID:30647129 NCBI chrNW_004955403:9,253,734...9,271,732
Ensembl chrNW_004955403:9,253,734...9,271,916 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO (PMID:22898811)
(PMID:30015240)		 UniProt PMID:22898811 PMID:30015240 RGD:15090842 NCBI chrNW_004955496:6,016,727...6,106,965
Ensembl chrNW_004955496:6,040,029...6,109,907 		JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955432:7,455,731...7,499,863
Ensembl chrNW_004955432:7,456,514...7,490,381 		JBrowse link
iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISO (PMID:17192393) UniProt PMID:17192393 NCBI chrNW_004955562:1,079,884...1,220,806
Ensembl chrNW_004955562:1,077,198...1,221,061 		JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of ISO (PMID:21700773) MGI PMID:21700773 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:18794901) UniProt PMID:18794901 NCBI chrNW_004955563:1,703,408...1,712,908
Ensembl chrNW_004955563:1,703,416...1,745,996 		JBrowse link
G Scara5 scavenger receptor class A member 5 involved_in ISO (PMID:19154717) UniProt PMID:19154717 NCBI chrNW_004955403:50,386,212...50,486,335
Ensembl chrNW_004955403:50,386,125...50,486,361 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(PMID:21653899)		 UniProt PMID:20682781 PMID:21653899 NCBI chrNW_004955403:45,828,247...45,867,309
Ensembl chrNW_004955403:45,827,942...45,867,309 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:12091367)
(PMID:21700773)		 BHF-UCL
MGI		 PMID:12091367 PMID:21700773 NCBI chrNW_004955403:9,253,734...9,271,732
Ensembl chrNW_004955403:9,253,734...9,271,916 		JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISO (PMID:33157103) UniProt PMID:33157103 NCBI chrNW_004955562:1,079,884...1,220,806
Ensembl chrNW_004955562:1,077,198...1,221,061 		JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116), (PMID:29237594) BHF-UCL PMID:15514116 PMID:29237594 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chrNW_004955455:9,833,924...9,840,547
Ensembl chrNW_004955455:9,833,924...9,841,619 		JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393 		JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (PMID:21700773) MGI PMID:21700773 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566 		JBrowse link
negative regulation of iron ion transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO RGD PMID:16116051 RGD:1599701 NCBI chrNW_004955435:22,414,605...22,421,682 JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Heph hephaestin involved_in ISO (PMID:30647129) UniProt PMID:30647129 NCBI chrNW_004955475:5,625,177...5,704,234
Ensembl chrNW_004955475:5,625,150...5,704,234 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
regulation of iron ion transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143 		JBrowse link
G LOC102027549 serotransferrin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910 		JBrowse link
transferrin transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap1 Rho GTPase activating protein 1 involved_in ISO (PMID:16380373) CAFA PMID:16380373 NCBI chrNW_004955422:1,378,426...1,395,439
Ensembl chrNW_004955422:1,378,426...1,396,899 		JBrowse link
G Cltc clathrin heavy chain involved_in ISO (PMID:14985334) BHF-UCL PMID:14985334 NCBI chrNW_004955451:3,380,304...3,445,973
Ensembl chrNW_004955451:3,380,304...3,445,973 		JBrowse link
G Dnm2 dynamin 2 involved_in ISO (PMID:14985334) BHF-UCL PMID:14985334 NCBI chrNW_004955495:1,860,644...1,934,589
Ensembl chrNW_004955495:1,860,644...1,934,818 		JBrowse link
G Lmtk2 lemur tyrosine kinase 2 involved_in ISO (PMID:18029400), (PMID:18429820) UniProt PMID:18029400 PMID:18429820 NCBI chrNW_004955460:14,012,047...14,101,969
Ensembl chrNW_004955460:14,012,363...14,098,542 		JBrowse link
G Myo1b myosin IB acts_upstream_of_or_within ISO (PMID:12490950) MGI PMID:12490950 NCBI chrNW_004955403:7,826,058...7,966,457
Ensembl chrNW_004955403:7,826,058...7,966,624 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO (PMID:10942597) UniProt PMID:10942597 NCBI chrNW_004955563:1,008,267...1,017,315
Ensembl chrNW_004955563:1,008,769...1,017,315 		JBrowse link
G Rep15 RAB15 effector protein involved_in ISO (PMID:16195351) UniProt PMID:16195351 NCBI chrNW_004955505:7,189,592...7,190,928
Ensembl chrNW_004955505:7,189,217...7,326,178 		JBrowse link
G Snx3 sorting nexin 3 acts_upstream_of_or_within ISO (PMID:23416069) MGI PMID:23416069 NCBI chrNW_004955411:33,339,974...33,344,563
Ensembl chrNW_004955411:33,340,274...33,345,500 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chrNW_004955573:272,315...289,227
Ensembl chrNW_004955573:272,289...291,668 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12593
    localization 4342
      establishment of localization 3713
        transport 3445
          monoatomic ion transport 906
            monoatomic cation transport 788
              metal ion transport 725
                transition metal ion transport 83
                  iron ion transport 45
                    iron coordination entity transport + 7
                    iron import into cell + 8
                    iron ion transmembrane transport + 19
                    lactoferrin transport 0
                    negative regulation of iron ion transport + 5
                    positive regulation of iron ion transport + 2
                    regulation of iron ion transport + 10
                    transferrin transport 10
                    xylem-to-phloem iron transport 0
paths to the root