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ONTOLOGY REPORT - ANNOTATIONS


Term:superoxide metabolic process
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Accession:GO:0006801 term browser browse the term
Definition:The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
Synonyms:exact_synonym: oxygen free radical metabolic process;   oxygen free radical metabolism;   superoxide free radical metabolic process;   superoxide free radical metabolism;   superoxide metabolism


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superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase IEA Ensembl GO_REF:0000107 NCBI chr31:37,230,900...37,247,170 JBrowse link
G CYB5R4 cytochrome b5 reductase 4 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:44,170,571...44,247,494
Ensembl chr12:44,141,582...44,247,493
JBrowse link
G CYBA cytochrome b-245 alpha chain ISO (PMID:1763037), (PMID:2243141) BHF-UCL
RGD
PMID:1763037, PMID:2243141, PMID:8798532, PMID:15322091 RGD:1580287, RGD:2317869 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893
JBrowse link
G CYBB cytochrome b-245 beta chain ISO (MGI:MGI:5568138|PMID:24739962)
(PMID:12042318)
UniProtKB
BHF-UCL
PMID:12042318, PMID:24739962 MGI:MGI:5568138 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217
JBrowse link
G IMMP2L inner mitochondrial membrane peptidase subunit 2 ISO (MGI:MGI:5299279|PMID:21824519) MGI PMID:21824519 MGI:MGI:5299279 NCBI chr14:50,487,679...51,336,906 JBrowse link
G NCF1 neutrophil cytosolic factor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458
JBrowse link
G NCF4 neutrophil cytosolic factor 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:27,597,296...27,672,199
Ensembl chr10:27,597,486...27,615,261
JBrowse link
G NOS2 nitric oxide synthase 2 ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588
JBrowse link
G NOX4 NADPH oxidase 4 ISO (PMID:18760347) CACAO
RGD
PMID:15322091, PMID:18760347 RGD:1580287 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277
JBrowse link
G NOXA1 NADPH oxidase activator 1 ISO (MGI:MGI:2449827|PMID:12473664)
(PMID:20609497)
MGI
UniProtKB
PMID:12473664, PMID:20609497 MGI:MGI:2449827 NCBI chr 9:48,306,652...48,316,196
Ensembl chr 9:48,313,723...48,316,201
JBrowse link
G NOXO1 NADPH oxidase organizer 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:38,951,926...38,956,134
Ensembl chr 6:38,953,741...38,956,115
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:17901563 RGD:5133248 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860
JBrowse link
G NRROS negative regulator of reactive oxygen species NOT IEA
ISO
(MGI:MGI:6192878|PMID:29909984) Ensembl
UniProt
PMID:29909984 GO_REF:0000107, MGI:MGI:6192878 NCBI chr33:29,682,182...29,699,469
Ensembl chr33:29,692,371...29,767,771
JBrowse link
G PIGX phosphatidylinositol glycan anchor biosynthesis class X IEA Ensembl GO_REF:0000107 NCBI chr33:29,740,435...29,767,931
Ensembl chr33:29,692,371...29,767,771
JBrowse link
G SH3PXD2A SH3 and PX domains 2A IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr28:15,936,927...16,165,537
Ensembl chr28:15,943,097...16,117,710
JBrowse link
G SH3PXD2B SH3 and PX domains 2B IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 4:39,854,213...39,950,704
Ensembl chr 4:39,854,211...39,949,958
JBrowse link
G SOD1 superoxide dismutase 1 ISO (PMID:12551919)
(MGI:MGI:2136726|PMID:11404260)
BHF-UCL
MGI
RGD
PMID:10640619, PMID:11404260, PMID:12514262, PMID:12551919 MGI:MGI:2136726, RGD:1601266, RGD:634854 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 ISO (PMID:12551919), (PMID:14980699)
(MGI:MGI:1332377|PMID:10049502)
(MGI:MGI:3577668|PMID:15637112)
(MGI:MGI:2386432|PMID:12176043)
BHF-UCL
MGI
PMID:10049502, PMID:12176043, PMID:12551919, PMID:14980699, PMID:15637112 MGI:MGI:1332377, MGI:MGI:2386432, MGI:MGI:3577668 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
negative regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AATF apoptosis antagonizing transcription factor IEA Ensembl GO_REF:0000107 NCBI chr 9:36,773,313...36,878,752
Ensembl chr 9:36,773,312...36,878,745
JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant IEA Ensembl GO_REF:0000107 NCBI chr20:49,812,444...49,816,262
Ensembl chr20:49,814,032...49,816,260
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:24601882 RGD:39128160 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G CRP C-reactive protein ISO RGD PMID:9767445 RGD:9586000 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
JBrowse link
G PON3 paraoxonase 3 ISO (MGI:MGI:5543365|PMID:22441669) CACAO PMID:22441669 MGI:MGI:5543365 NCBI chr14:20,615,180...20,642,807
Ensembl chr14:20,565,641...20,642,985
JBrowse link
positive regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:21376054 RGD:5129173 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:21076237 RGD:5129195 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238
JBrowse link
G APP amyloid beta precursor protein ISO (PMID:11316806) ARUK-UCL PMID:11316806 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G B9D2 B9 domain containing 2 ISS AgBase GO_REF:0000024 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G CD177 CD177 molecule ISO (PMID:21193407) UniProt PMID:21193407 NCBI chr 1:111,693,234...111,698,879
Ensembl chr 1:111,693,005...111,698,742
JBrowse link
G CLEC1A C-type lectin domain family 1 member A IEA Ensembl GO_REF:0000107 NCBI chr27:35,896,421...35,920,649
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G CLEC7A C-type lectin domain containing 7A IEA Ensembl GO_REF:0000107 NCBI chr27:35,852,685...35,885,673
Ensembl chr27:35,853,099...36,007,157
JBrowse link
G CRP C-reactive protein IEA Ensembl GO_REF:0000107 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
JBrowse link
G CYBA cytochrome b-245 alpha chain ISO RGD PMID:15036821 RGD:8693734 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:22966991 RGD:7204494 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G F2RL1 F2R like trypsin receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
G FPR2 formyl peptide receptor 2 ISO (MGI:MGI:5905278|PMID:11316806) ARUK-UCL PMID:11316806 MGI:MGI:5905278 NCBI chr 1:105,343,096...105,353,563
Ensembl chr 1:105,344,463...105,372,070
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697
JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chr 6:42,275,060...42,315,545
Ensembl chr 6:42,276,998...42,315,533
JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO (MGI:MGI:5009187|PMID:11408560) BHF-UCL PMID:11408560 MGI:MGI:5009187 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G HVCN1 hydrogen voltage gated channel 1 ISO RGD PMID:24935944 RGD:14985214 NCBI chr26:8,437,032...8,474,831
Ensembl chr26:8,419,269...8,466,523
JBrowse link
G IL18 interleukin 18 ISO RGD PMID:19497959 RGD:4889403 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G ITGAM integrin subunit alpha M IEA Ensembl GO_REF:0000107 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G ITGB2 integrin subunit beta 2 IEA Ensembl GO_REF:0000107 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018
JBrowse link
G MAPT microtubule associated protein tau IEA Ensembl GO_REF:0000107 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO (PMID:24141169) AgBase PMID:24141169 NCBI chr27:35,828,852...35,838,748
Ensembl chr27:35,828,029...35,838,754
JBrowse link
G PRKCD protein kinase C delta ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191
JBrowse link
G SOD1 superoxide dismutase 1 IEA Ensembl GO_REF:0000107 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SYK spleen associated tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
G TGFB1 transforming growth factor beta 1 ISS UniProtKB GO_REF:0000024 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP IEA Ensembl GO_REF:0000107 NCBI chr 1:116,757,271...116,760,453
Ensembl chr 1:116,757,289...116,772,325
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639
JBrowse link
G FBLN5 fibulin 5 IEA Ensembl GO_REF:0000107 NCBI chr 8:1,162,203...1,231,809
Ensembl chr 8:1,162,923...1,231,719
JBrowse link
G GCH1 GTP cyclohydrolase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYK spleen associated tyrosine kinase ISO (MGI:MGI:4414596|PMID:19797524) UniProtKB PMID:19797524 MGI:MGI:4414596 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
regulation of superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHC1 SHC adaptor protein 1 ISO (PMID:24177325) BHF-UCL PMID:24177325 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 IEA Ensembl GO_REF:0000107 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837
JBrowse link
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:3616392|PMID:16371425) MGI PMID:16371425 MGI:MGI:3616392 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G CCS copper chaperone for superoxide dismutase IEA
IBA
(PMID:21873635) GOC
GO_Central
PMID:21873635 GO_REF:0000108 NCBI chr18:50,748,039...50,759,270
Ensembl chr18:50,748,041...50,759,191
JBrowse link
G FANCC FA complementation group C IEA Ensembl GO_REF:0000107 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506
JBrowse link
G LOC475156 peroxiredoxin 1 pseudogene IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:50,791,386...50,792,228 JBrowse link
G MPO myeloperoxidase IEA Ensembl GO_REF:0000107 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820
JBrowse link
G MT3 metallothionein 3 IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
G NOS3 nitric oxide synthase 3 IEA Ensembl GO_REF:0000107 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G PRDX1 peroxiredoxin 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:14,834,009...14,855,665
Ensembl chr15:14,838,652...14,862,971
JBrowse link
G PRDX2 peroxiredoxin 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682
JBrowse link
G SOD1 superoxide dismutase 1 ISS
IBA
IEA
(PMID:21873635) UniProtKB
GO_Central
GOC
PMID:21873635 GO_REF:0000024, GO_REF:0000108 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 IEA GOC GO_REF:0000108 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G SOD3 superoxide dismutase 3 IBA
IEA
(PMID:21873635) GO_Central
GOC
PMID:21873635 GO_REF:0000108 NCBI chr 3:85,382,698...85,387,144
Ensembl chr 3:85,382,484...85,387,455
JBrowse link
superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain ISO (PMID:2243141)
PMID:8798532
BHF-UCL PMID:2243141, PMID:8798532 RGD:2317869 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893
JBrowse link
G CYBB cytochrome b-245 beta chain IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217
JBrowse link
G DUOX1 dual oxidase 1 NAS
IBA
(PMID:10806195)
(PMID:21873635)
UniProtKB
GO_Central
PMID:10806195, PMID:21873635 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202
JBrowse link
G DUOX2 dual oxidase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716
JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:16788136 RGD:4892602 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383
JBrowse link
G NCF1 neutrophil cytosolic factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458
JBrowse link
G NCF2 neutrophil cytosolic factor 2 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 7:16,914,629...16,946,370
Ensembl chr 7:16,904,031...16,945,372
JBrowse link
G NOX1 NADPH oxidase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698
JBrowse link
G NOX3 NADPH oxidase 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:45,129,112...45,186,510
Ensembl chr 1:45,128,958...45,186,510
JBrowse link
G NOX4 NADPH oxidase 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277
JBrowse link
G NOX5 NADPH oxidase 5 IEA InterPro
Ensembl
GO_REF:0000002, GO_REF:0000107 NCBI chr30:32,929,287...32,985,944
Ensembl chr30:32,951,501...32,986,559
JBrowse link
G NOXA1 NADPH oxidase activator 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:48,306,652...48,316,196
Ensembl chr 9:48,313,723...48,316,201
JBrowse link
G PRG3 proteoglycan 3, pro eosinophil major basic protein 2 IEA Ensembl GO_REF:0000107 NCBI chr18:38,765,682...38,769,711
Ensembl chr18:38,766,095...38,769,711
JBrowse link
G SOD1 superoxide dismutase 1 IEA Ensembl GO_REF:0000107 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 ISO (MGI:MGI:3654558|PMID:10212301)
(MGI:MGI:3625564|PMID:15781740)
(MGI:MGI:3653322|PMID:16677818)
MGI PMID:10212301, PMID:15781740, PMID:16677818 MGI:MGI:3625564, MGI:MGI:3653322, MGI:MGI:3654558 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G TAFA4 TAFA chemokine like family member 4 IEA Ensembl GO_REF:0000107 NCBI chr20:22,843,151...22,963,722
Ensembl chr20:22,837,094...22,962,831
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    cellular process 15465
      cellular metabolic process 9650
        reactive oxygen species metabolic process 300
          superoxide metabolic process 71
            regulation of superoxide metabolic process + 35
            removal of superoxide radicals + 17
            superoxide anion generation + 44
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.