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ONTOLOGY REPORT - ANNOTATIONS


Term:superoxide metabolic process
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Accession:GO:0006801 term browser browse the term
Definition:The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
Synonyms:exact_synonym: oxygen free radical metabolic process;   oxygen free radical metabolism;   superoxide free radical metabolic process;   superoxide free radical metabolism;   superoxide metabolism


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superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta-synthase ISO (MGI:MGI:1888627|PMID:10953023) MGI PMID:10953023 MGI:MGI:1888627 NCBI chrNW_004955407:38,924,355...38,939,790 JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 ISO (MGI:MGI:5299279|PMID:21824519) MGI PMID:21824519 MGI:MGI:5299279 NCBI chrNW_004955410:14,567,787...15,420,025
Ensembl chrNW_004955410:14,567,951...15,354,190
JBrowse link
G LOC102004641 cytochrome b-245 light chain ISO (PMID:1763037), (PMID:2243141) BHF-UCL
RGD
PMID:1763037, PMID:2243141, PMID:8798532, PMID:15322091 RGD:1580287, RGD:2317869 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118
JBrowse link
G LOC102012042 cytochrome b-245 heavy chain ISO (PMID:12042318)
(MGI:MGI:5568138|PMID:24739962)
BHF-UCL
UniProtKB
PMID:12042318, PMID:24739962 MGI:MGI:5568138 NCBI chrNW_004955587:781,533...818,149
Ensembl chrNW_004955587:781,388...819,912
JBrowse link
G LOC102015388 cytochrome b5 reductase 4 ISO (PMID:10611283) UniProtKB PMID:10611283 NCBI chrNW_004955411:11,424,923...11,508,193
Ensembl chrNW_004955411:11,424,505...11,508,193
JBrowse link
G Nos2 nitric oxide synthase 2 ISO (MGI:MGI:2673089|PMID:12933833) MGI PMID:12933833 MGI:MGI:2673089 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Nox4 NADPH oxidase 4 ISO (PMID:18760347) CACAO
RGD
PMID:15322091, PMID:18760347 RGD:1580287 NCBI chrNW_004955414:4,062,337...4,220,032
Ensembl chrNW_004955414:4,062,081...4,212,746
JBrowse link
G Noxa1 NADPH oxidase activator 1 ISO (MGI:MGI:2449827|PMID:12473664)
(PMID:20609497)
MGI
UniProtKB
PMID:12473664, PMID:20609497 MGI:MGI:2449827 NCBI chrNW_004955513:5,345,521...5,352,879
Ensembl chrNW_004955513:5,345,619...5,352,834
JBrowse link
G Noxo1 NADPH oxidase organizer 1 ISO (MGI:MGI:2449827|PMID:12473664) MGI PMID:12473664 MGI:MGI:2449827 NCBI chrNW_004955442:15,288,495...15,290,601
Ensembl chrNW_004955442:15,288,602...15,290,418
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:17901563 RGD:5133248 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604
JBrowse link
G Nrros negative regulator of reactive oxygen species NOT ISO (MGI:MGI:5568138|PMID:24739962)
(MGI:MGI:6192878|PMID:29909984)
UniProtKB
UniProt
PMID:24739962, PMID:29909984 MGI:MGI:5568138, MGI:MGI:6192878 NCBI chrNW_004955420:12,792,173...12,798,645
Ensembl chrNW_004955420:12,792,111...12,801,963
JBrowse link
G Sh3pxd2a SH3 and PX domains 2A ISO (PMID:20609497)
(PMID:19755710)
UniProtKB PMID:19755710, PMID:20609497 NCBI chrNW_004955485:6,811,857...7,008,011
Ensembl chrNW_004955485:6,811,844...7,009,432
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B ISO (PMID:19755710) UniProtKB PMID:19755710 NCBI chrNW_004955408:25,103,278...25,169,934
Ensembl chrNW_004955408:25,103,278...25,170,003
JBrowse link
G Sod1 superoxide dismutase 1 ISO (MGI:MGI:2136726|PMID:11404260)
(PMID:12551919)
RGD
MGI
BHF-UCL
PMID:10640619, PMID:11404260, PMID:12514262, PMID:12551919 MGI:MGI:2136726, RGD:1601266, RGD:634854 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod2 superoxide dismutase 2 ISO (PMID:12551919), (PMID:14980699)
(MGI:MGI:1332377|PMID:10049502)
(MGI:MGI:3577668|PMID:15637112)
(MGI:MGI:2386432|PMID:12176043)
BHF-UCL
MGI
PMID:10049502, PMID:12176043, PMID:12551919, PMID:14980699, PMID:15637112 MGI:MGI:1332377, MGI:MGI:2386432, MGI:MGI:3577668 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
negative regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor ISO (PMID:15207272) UniProtKB PMID:15207272 NCBI chrNW_004955451:929,278...1,033,665
Ensembl chrNW_004955451:929,510...1,033,492
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant ISO (MGI:MGI:1930064|PMID:11168643) MGI PMID:11168643 MGI:MGI:1930064 NCBI chrNW_004955495:2,418,113...2,421,181
Ensembl chrNW_004955495:2,418,364...2,421,538
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:24601882 RGD:39128160 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Pon3 paraoxonase 3 ISO (MGI:MGI:5543365|PMID:22441669) CACAO PMID:22441669 MGI:MGI:5543365 NCBI chrNW_004955432:11,945,383...11,983,417
Ensembl chrNW_004955432:11,942,922...11,983,504
JBrowse link
positive regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO RGD PMID:21376054 RGD:5129173 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:21076237 RGD:5129195 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255
JBrowse link
G App amyloid beta precursor protein ISO (PMID:11316806) ARUK-UCL PMID:11316806 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
G Cd177 CD177 molecule ISO (PMID:21193407) UniProt PMID:21193407 NCBI chrNW_004955555:1,106,722...1,120,756 JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:22966991 RGD:7204494 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO (PMID:11714832) UniProtKB PMID:11714832 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chrNW_004955532:2,059,038...2,079,120
Ensembl chrNW_004955532:2,059,038...2,079,957
JBrowse link
G Gnai3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chrNW_004955435:12,965,006...13,005,614
Ensembl chrNW_004955435:12,965,006...13,005,614
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO (MGI:MGI:5009187|PMID:11408560) BHF-UCL PMID:11408560 MGI:MGI:5009187 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428
JBrowse link
G Hvcn1 hydrogen voltage gated channel 1 ISO RGD PMID:24935944 RGD:14985214 NCBI chrNW_004955482:7,529,009...7,563,273
Ensembl chrNW_004955482:7,529,277...7,538,363
JBrowse link
G Il18 interleukin 18 ISO RGD PMID:19497959 RGD:4889403 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
JBrowse link
G Itgam integrin subunit alpha M ISO (MGI:MGI:3814938|PMID:18981141)
(PMID:21193407)
(MGI:MGI:3812233|PMID:18685038)
ARUK-UCL
UniProt
PMID:18685038, PMID:18981141, PMID:21193407 MGI:MGI:3812233, MGI:MGI:3814938 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759
JBrowse link
G Itgb2 integrin subunit beta 2 ISO (PMID:21193407) UniProt PMID:21193407 NCBI chrNW_004955407:41,779,849...41,805,637
Ensembl chrNW_004955407:41,777,777...41,800,201
JBrowse link
G LOC102004641 cytochrome b-245 light chain ISO RGD PMID:15036821 RGD:8693734 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118
JBrowse link
G Mapt microtubule associated protein tau ISO (PMID:22920254) ParkinsonsUK-UCL PMID:22920254 NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442
JBrowse link
G Prkcd protein kinase C delta ISO (PMID:19801500) UniProtKB PMID:19801500 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274
JBrowse link
G Sod1 superoxide dismutase 1 ISO (PMID:18219391) UniProtKB PMID:18219391 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Syk spleen associated tyrosine kinase ISO (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581
JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:22073128) BHF-UCL PMID:22073128 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP ISO (MGI:MGI:3812233|PMID:18685038) ARUK-UCL PMID:18685038 MGI:MGI:3812233 NCBI chrNW_004955468:2,673,657...2,677,633
Ensembl chrNW_004955468:2,673,980...2,677,321
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule ISO (MGI:MGI:4850200|PMID:20978343) BHF-UCL PMID:20978343 MGI:MGI:4850200 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Dhfr dihydrofolate reductase ISO (MGI:MGI:5645206|PMID:19666465) BHF-UCL PMID:19666465 MGI:MGI:5645206 NCBI chrNW_004955418:29,274,170...29,283,028 JBrowse link
G Fbln5 fibulin 5 ISO (MGI:MGI:3610795|PMID:15528465) BHF-UCL PMID:15528465 MGI:MGI:3610795 NCBI chrNW_004955438:14,073,927...14,144,644
Ensembl chrNW_004955438:14,071,410...14,145,070
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO (PMID:19666465) BHF-UCL PMID:19666465 NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO (MGI:MGI:4850200|PMID:20978343) BHF-UCL PMID:20978343 MGI:MGI:4850200 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syk spleen associated tyrosine kinase ISO (MGI:MGI:4414596|PMID:19797524) UniProtKB PMID:19797524 MGI:MGI:4414596 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581
JBrowse link
regulation of superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shc1 SHC adaptor protein 1 ISO (PMID:24177325) BHF-UCL PMID:24177325 NCBI chrNW_004955545:1,468,391...1,479,209
Ensembl chrNW_004955545:1,468,391...1,476,814
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 ISO (PMID:16945374) HGNC PMID:16945374 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Atp7a ATPase copper transporting alpha ISO (MGI:MGI:3616392|PMID:16371425) MGI PMID:16371425 MGI:MGI:3616392 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393
JBrowse link
G Fancc FA complementation group C ISO (MGI:MGI:2149223|PMID:11493445) MGI PMID:11493445 MGI:MGI:2149223 NCBI chrNW_004955422:22,031,825...22,246,478
Ensembl chrNW_004955422:22,032,258...22,247,044
JBrowse link
G Mpo myeloperoxidase ISO (MGI:MGI:1333719|PMID:10085024) MGI PMID:10085024 MGI:MGI:1333719 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Nos3 nitric oxide synthase 3 ISO (PMID:19666465) BHF-UCL PMID:19666465 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Prdx1 peroxiredoxin 1 ISO (MGI:MGI:3695235|PMID:16880205)
(MGI:MGI:3611115|PMID:16170382)
MGI PMID:16170382, PMID:16880205 MGI:MGI:3611115, MGI:MGI:3695235 NCBI chrNW_004955464:12,761,390...12,773,413
Ensembl chrNW_004955464:12,761,401...12,773,146
JBrowse link
G Prdx2 peroxiredoxin 2 ISO (PMID:20978343)
(MGI:MGI:4850200|PMID:20978343)
BHF-UCL PMID:20978343 MGI:MGI:4850200 NCBI chrNW_004955415:31,880,801...31,884,453
Ensembl chrNW_004955415:31,880,588...31,884,778
JBrowse link
G Sod1 superoxide dismutase 1 ISO (MGI:MGI:1342989|PMID:10436316), (MGI:MGI:1351737|PMID:10471451), (MGI:MGI:2149223|PMID:11493445), (MGI:MGI:80951|PMID:8673102)
(MGI:MGI:1353351|PMID:10679476)
(MGI:MGI:3625573|PMID:12433839), (MGI:MGI:3710732|PMID:17448893)
(MGI:MGI:2149223|PMID:11493445)
(MGI:MGI:1201750|PMID:9516486), (MGI:MGI:1314762|PMID:9788901)
RGD
MGI
PMID:8673102, PMID:9516486, PMID:9788901, PMID:10436316, PMID:10471451, PMID:10640619, PMID:10679476, PMID:11493445, PMID:12433839, PMID:12514262, PMID:17448893, PMID:21757500 MGI:MGI:1201750, MGI:MGI:1314762, MGI:MGI:1342989, MGI:MGI:1351737, MGI:MGI:1353351, MGI:MGI:2149223, MGI:MGI:3625573, MGI:MGI:3710732, MGI:MGI:80951, RGD:1601266, RGD:634854, RGD:8655968 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod2 superoxide dismutase 2 ISO (MGI:MGI:3765405|PMID:16873728)
(PMID:16179351)
RGD
MGI
BHF-UCL
PMID:12107766, PMID:15642720, PMID:16179351, PMID:16873728, PMID:19439219 MGI:MGI:3765405, RGD:2291939, RGD:2291946, RGD:2317387 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duox2 dual oxidase 2 ISO (PMID:22814254) UniProt PMID:22814254 NCBI chrNW_004955409:8,270,657...8,288,201
Ensembl chrNW_004955409:8,271,164...8,287,096
JBrowse link
G Edn1 endothelin 1 ISO RGD PMID:16788136 RGD:4892602 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
JBrowse link
G LOC102004641 cytochrome b-245 light chain ISO (PMID:2243141)
PMID:8798532
BHF-UCL PMID:2243141, PMID:8798532 RGD:2317869 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118
JBrowse link
G LOC102012042 cytochrome b-245 heavy chain ISO (PMID:12042318) BHF-UCL PMID:12042318 NCBI chrNW_004955587:781,533...818,149
Ensembl chrNW_004955587:781,388...819,912
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO (PMID:2547247)
(MGI:MGI:1354608|PMID:10725280), (MGI:MGI:1930845|PMID:11156938)
UniProtKB
MGI
PMID:2547247, PMID:10725280, PMID:11156938 MGI:MGI:1354608, MGI:MGI:1930845 NCBI chrNW_004955456:13,353,780...13,363,956
Ensembl chrNW_004955456:13,354,011...13,363,891
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 ISO (MGI:MGI:1196082|PMID:9490028) MGI PMID:9490028 MGI:MGI:1196082 NCBI chrNW_004955406:22,355,717...22,384,746
Ensembl chrNW_004955406:22,355,724...22,384,864
JBrowse link
G Nox1 NADPH oxidase 1 ISO (PMID:10485709)
(MGI:MGI:3796728|PMID:18397177)
(PMID:18023288)
(MGI:MGI:2449827|PMID:12473664)
BHF-UCL
MGI
PMID:10485709, PMID:12473664, PMID:18023288, PMID:18397177 MGI:MGI:2449827, MGI:MGI:3796728, RGD:633401 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618
JBrowse link
G Nox3 NADPH oxidase 3 ISO (MGI:MGI:3512869|PMID:15326186) MGI PMID:15326186 MGI:MGI:3512869 NCBI chrNW_004955439:6,764,693...6,820,278
Ensembl chrNW_004955439:6,764,693...6,820,278
JBrowse link
G Nox4 NADPH oxidase 4 ISO (MGI:MGI:3694159|PMID:10869423) UniProtKB PMID:10869423 MGI:MGI:3694159 NCBI chrNW_004955414:4,062,337...4,220,032
Ensembl chrNW_004955414:4,062,081...4,212,746
JBrowse link
G Sod1 superoxide dismutase 1 ISO (MGI:MGI:3522379|PMID:15317809) MGI PMID:15317809 MGI:MGI:3522379 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod2 superoxide dismutase 2 ISO (MGI:MGI:3625564|PMID:15781740)
(MGI:MGI:3654558|PMID:10212301)
(MGI:MGI:3653322|PMID:16677818)
MGI PMID:10212301, PMID:15781740, PMID:16677818 MGI:MGI:3625564, MGI:MGI:3653322, MGI:MGI:3654558 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link
G Tafa4 TAFA chemokine like family member 4 ISO (MGI:MGI:6282963|PMID:25109685) UniProt PMID:25109685 MGI:MGI:6282963 NCBI chrNW_004955421:18,920,551...19,083,792
Ensembl chrNW_004955421:18,920,551...19,083,915
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    cellular process 11094
      cellular metabolic process 7025
        reactive oxygen species metabolic process 266
          superoxide metabolic process 57
            regulation of superoxide metabolic process + 30
            removal of superoxide radicals + 14
            superoxide anion generation + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.