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ONTOLOGY REPORT - ANNOTATIONS


Term:fat-soluble vitamin metabolic process
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Accession:GO:0006775 term browser browse the term
Definition:The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms:exact_synonym: fat-soluble vitamin metabolism


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101963150 sterol 26-hydroxylase, mitochondrial involved_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936569:1,213,700...1,250,181
Ensembl chrNW_004936569:1,213,573...1,250,589
JBrowse link
G LOC101972957 vitamin D 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:3,881,630...3,897,613
Ensembl chrNW_004936528:3,881,087...3,900,302
JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in IEA Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936646:1,899,686...1,904,104
Ensembl chrNW_004936646:1,900,259...1,904,104
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,456,498...4,462,436
Ensembl chrNW_004936514:4,456,484...4,462,987
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936590:3,813,916...3,817,642
Ensembl chrNW_004936590:3,813,888...3,817,642
JBrowse link
phylloquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936474:284,630...293,090
Ensembl chrNW_004936474:284,569...295,572
JBrowse link
phylloquinone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr3 carbonyl reductase 3 ISO menadione catabolism RGD PMID:18983987 RGD:2316293 NCBI chrNW_004936500:6,461,776...6,469,063
Ensembl chrNW_004936500:6,458,721...6,591,928
JBrowse link
G LOC101975902 leukotriene-B4 omega-hydroxylase 3-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936596:4,928,251...4,981,931
Ensembl chrNW_004936596:4,927,264...4,981,971
JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
JBrowse link
G Tnf tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
JBrowse link
regulation of vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:18000880 RGD:10400849 NCBI chrNW_004936470:7,916,438...7,926,089
Ensembl chrNW_004936470:7,916,438...7,926,088
JBrowse link
G Isx intestine specific homeobox acts_upstream_of_or_within ISO (MGI:3775349|PMID:18093975) MGI PMID:18093975 MGI:3775349 NCBI chrNW_004936492:5,245,211...5,265,419
Ensembl chrNW_004936492:5,245,211...5,265,419
JBrowse link
retinoic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101970215 cytochrome P450 2W1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:1,203,004...1,208,131
Ensembl chrNW_004936754:1,203,017...1,208,131
JBrowse link
G LOC101975674 cytochrome P450 26B1 involved_in ISO
IEA
RGD
Ensembl
PMID:21138835 GO_REF:0000107 RGD:6771354 NCBI chrNW_004936491:16,010,394...16,028,852
Ensembl chrNW_004936491:16,010,070...16,028,895
JBrowse link
G LOC101977861 cytochrome P450 26A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074
JBrowse link
G LOC101978131 cytochrome P450 26C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:1,818,037...1,828,400
Ensembl chrNW_004936601:1,817,983...1,828,185
JBrowse link
vitamin A metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101960702 lysosomal acid lipase/cholesteryl ester hydrolase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:4,975,296...5,008,938
Ensembl chrNW_004936601:4,975,211...5,008,962
JBrowse link
G Lrat lecithin retinol acyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1928450|PMID:11108736) Ensembl
TreeGrafter
MGI
PMID:11108736 GO_REF:0000107 GO_REF:0000118 MGI:1928450 NCBI chrNW_004936576:1,491,480...1,498,568
Ensembl chrNW_004936576:1,492,297...1,501,917
JBrowse link
G Rbp1 retinol binding protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936540:1,600,673...1,626,573
Ensembl chrNW_004936540:1,600,398...1,626,652
JBrowse link
vitamin D catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf23 fibroblast growth factor 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936606:4,555,034...4,561,961
Ensembl chrNW_004936606:4,555,034...4,561,961
JBrowse link
G LOC101957714 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:1,899,686...1,904,104
Ensembl chrNW_004936646:1,900,259...1,904,104
JBrowse link
vitamin D metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf23 fibroblast growth factor 23 ISO RGD PMID:15531762 RGD:1598934 NCBI chrNW_004936606:4,555,034...4,561,961
Ensembl chrNW_004936606:4,555,034...4,561,961
JBrowse link
G Gc GC vitamin D binding protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3046628|PMID:15225763) MGI
Ensembl
PMID:15225763 GO_REF:0000107 MGI:3046628 NCBI chrNW_004936598:3,220,029...3,256,091
Ensembl chrNW_004936598:3,219,991...3,261,629
JBrowse link
G LOC101957714 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:3046628|PMID:15225763) RGD
Ensembl
MGI
PMID:1991512 PMID:15225763 GO_REF:0000107 MGI:3046628 RGD:1298844 NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
JBrowse link
G LOC101972957 vitamin D 25-hydroxylase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677973|PMID:12867411) MGI
Ensembl
PMID:12867411 GO_REF:0000107 MGI:2677973 NCBI chrNW_004936528:3,881,630...3,897,613
Ensembl chrNW_004936528:3,881,087...3,900,302
JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in ISO
IEA
RGD
Ensembl
PMID:9371776 GO_REF:0000107 RGD:69372 NCBI chrNW_004936646:1,899,686...1,904,104
Ensembl chrNW_004936646:1,900,259...1,904,104
JBrowse link
G Lrp2 LDL receptor related protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1331347|PMID:10052453) MGI
Ensembl
PMID:10052453 GO_REF:0000107 MGI:1331347 NCBI chrNW_004936469:10,245,001...10,438,933
Ensembl chrNW_004936469:10,244,881...10,438,935
JBrowse link
vitamin D3 metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:6282476|PMID:28798354) MGI PMID:28798354 MGI:6282476 NCBI chrNW_004937067:194,375...246,607 JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5548021|PMID:24259513) MGI
Ensembl
PMID:24259513 GO_REF:0000107 MGI:5548021 NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 acts_upstream_of_or_within ISO (MGI:5548021|PMID:24259513) MGI PMID:24259513 MGI:5548021 NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pltp phospholipid transfer protein acts_upstream_of_or_within ISO (MGI:3622506|PMID:16467369) MGI PMID:16467369 MGI:3622506 NCBI chrNW_004936514:7,121,023...7,131,475 JBrowse link
vitamin E metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101969421 cytochrome P450 1A2 ISO RGD PMID:16520233 RGD:401900296 NCBI chrNW_004936471:33,704,616...33,709,455
Ensembl chrNW_004936471:33,703,792...33,709,484
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:28315682) UniProt PMID:28315682 NCBI chrNW_004936478:19,434,557...19,452,245
Ensembl chrNW_004936478:19,434,557...19,452,248
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:19,771,384...19,785,034
Ensembl chrNW_004936475:19,769,488...19,785,311
JBrowse link
G Ttpa alpha tocopherol transfer protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1929784|PMID:11076932), (MGI:3691723|PMID:16014812)
(MGI:1928440|PMID:11095717)
Ensembl
TreeGrafter
MGI
PMID:11076932 PMID:11095717 PMID:16014812 GO_REF:0000107 GO_REF:0000118 MGI:1928440 MGI:1929784 MGI:3691723 NCBI chrNW_004936496:10,409,948...10,466,722
Ensembl chrNW_004936496:10,454,605...10,465,301
JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:284,630...293,090
Ensembl chrNW_004936474:284,569...295,572
JBrowse link
vitamin K metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm2 apoptosis inducing factor mitochondria associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:8,466,089...8,474,198
Ensembl chrNW_004936521:8,466,086...8,474,198
JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO (PMID:18449627) UniProt PMID:18449627 NCBI chrNW_004936500:6,569,708...6,591,266
Ensembl chrNW_004936500:6,458,721...6,591,928
JBrowse link
G Ggcx gamma-glutamyl carboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936712:1,696,264...1,709,087
Ensembl chrNW_004936712:1,699,750...1,709,087
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:19,771,384...19,785,034
Ensembl chrNW_004936475:19,769,488...19,785,311
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3604816|PMID:15879509) MGI
TreeGrafter
Ensembl
InterPro
PMID:15879509 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 MGI:3604816 NCBI chrNW_004936501:13,459,400...13,461,864
Ensembl chrNW_004936501:13,459,022...13,462,174
JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex subunit 1 like 1 involved_in IEA InterPro
TreeGrafter
Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936543:7,733,420...7,775,691
Ensembl chrNW_004936543:7,733,367...7,759,582
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15868
    metabolic process 9524
      small molecule metabolic process 1623
        vitamin metabolic process 90
          fat-soluble vitamin metabolic process 36
            fat-soluble vitamin biosynthetic process + 9
            fat-soluble vitamin catabolic process + 9
            vitamin A metabolic process + 5
            vitamin D metabolic process + 14
            vitamin E metabolic process + 5
            vitamin K metabolic process + 9
paths to the root