Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:folic acid-containing compound metabolic process
go back to main search page
Accession:GO:0006760 term browser browse the term
Definition:The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
Synonyms:exact_synonym: folate and derivative metabolic process;   folate and derivative metabolism;   folate-containing compound metabolic process;   folate-containing compound metabolism;   folic acid and derivative metabolic process;   folic acid and derivative metabolism;   folic acid-containing compound metabolism;   vitamin B9 and derivative metabolic process;   vitamin B9 and derivative metabolism;   vitamin M and derivative metabolic process;   vitamin M and derivative metabolism



show annotations for term's descendants           Sort by:
 
folic acid-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPGN epithelial mitogen involved_in IEA UniProt GO_REF:0000117 NCBI chr 8:70,266,867...70,301,250
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
G FOLH1B folate hydrolase 1B acts_upstream_of_or_within ISO (MGI:1934060|PMID:11210180) MGI PMID:11210180 MGI:1934060 NCBI chr 9:22,903,997...22,960,648
Ensembl chr 9:22,903,973...22,963,471
JBrowse link
G FPGS folylpolyglutamate synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:268,281,298...268,309,397
Ensembl chr 1:268,287,729...268,309,411
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,898...15,329,966
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA UniProt
UniProt
GO_REF:0000117 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,819,612...68,853,067
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IEA UniProt
UniProt
GO_REF:0000117 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,898...15,329,966
JBrowse link
10-formyltetrahydrofolate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase acts_upstream_of_positive_effect ISO (PMID:19933275), (PMID:21238436) UniProt PMID:19933275 PMID:21238436 NCBI chr 9:35,903,902...35,948,573
Ensembl chr 9:35,904,029...35,948,575
JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in IEA UniProt
UniProt
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:53,748,585...53,794,777
Ensembl chr 7:53,748,585...53,794,706
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA Ensembl
UniProt
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 5:79,492,672...79,558,702
Ensembl chr 5:79,492,732...79,558,701
JBrowse link
10-formyltetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
dihydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:8948466 RGD:5144056 NCBI chr15:117,617,584...117,649,063
Ensembl chr15:117,617,502...117,649,107
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO (PMID:2303423), (PMID:23707606) RGD
BHF-UCL
PMID:2303423 PMID:3970530 PMID:11502523 PMID:23707606 RGD:1298877 RGD:2300196 NCBI chr 2:89,230,660...89,255,830 JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102167410 5-formyltetrahydrofolate cyclo-ligase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chr 7:48,717,518...48,873,492 JBrowse link
G PM20D2 peptidase M20 domain containing 2 NOT|involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:57,188,019...57,219,243
Ensembl chr 1:57,188,535...57,219,233
JBrowse link
folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in ISO PMID:1848231 UniProt PMID:1848231 RGD:632027 NCBI chr 7:53,748,585...53,794,777
Ensembl chr 7:53,748,585...53,794,706
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:79,492,672...79,558,702
Ensembl chr 5:79,492,732...79,558,701
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO PMID:20424322 BHF-UCL PMID:20424322 RGD:10054082 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G FOLR1 folate receptor alpha acts_upstream_of_or_within ISO (MGI:2669340|PMID:12854656) MGI PMID:12854656 MGI:2669340 NCBI chr 9:6,753,513...6,760,433
Ensembl chr 9:6,746,007...6,760,433
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,224...74,270,802
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
UniProt
GO_Central
PMID:21873635 GO_REF:0000002 GO_REF:0000117 NCBI chr 1:268,281,298...268,309,397
Ensembl chr 1:268,287,729...268,309,411
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:7057182 RGD:2301991 NCBI chr15:117,617,584...117,649,063
Ensembl chr15:117,617,502...117,649,107
JBrowse link
G DHFR dihydrofolate reductase involved_in IEA
ISO
UniProt
UniProt
InterPro
RGD
PMID:11502523 GO_REF:0000002 GO_REF:0000041 RGD:1298877 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO RGD PMID:4078017 RGD:2301990 NCBI chr13:197,130,898...197,158,797
Ensembl chr13:197,130,904...197,161,891
JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 1:184,201,232...184,264,060
Ensembl chr 1:184,202,007...184,257,315
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 2:87,791,827...87,867,189
Ensembl chr 2:87,678,811...87,866,856
JBrowse link
G EPGN epithelial mitogen involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 8:70,266,867...70,301,250
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase involved_in IEA UniProt
UniProt
GO_REF:0000041
G LOC102167410 5-formyltetrahydrofolate cyclo-ligase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chr 7:48,717,518...48,873,492 JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
UniProt
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,898...15,329,966
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,819,612...68,853,067
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IBA
ISO
(PMID:21873635) GO_Central
GO_Central
RGD
PMID:21163947 PMID:21873635 RGD:7244288 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IBA
IEA
(PMID:21873635) GO_Central
GO_Central
Ensembl
UniProt
UniProt
PMID:21873635 GO_REF:0000041 GO_REF:0000107 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 1:273,230,357...273,295,170
Ensembl chr 1:273,228,838...273,295,104
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
UniProt
InterPro
Ensembl
GO_Central
GO_Central
PMID:21873635 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA
IBA
(PMID:21873635) UniProt
InterPro
GO_Central
UniProt
Ensembl
GO_Central
PMID:21873635 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
G TYMS thymidylate synthetase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,640,031...105,660,601
JBrowse link
tetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G LOC100515508 peroxisomal sarcosine oxidase involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr12:45,306,327...45,319,938
Ensembl chr12:45,257,188...45,322,767
JBrowse link
G LOC102167410 5-formyltetrahydrofolate cyclo-ligase involved_in ISO (PMID:19738041), (PMID:7766710) BHF-UCL PMID:7766710 PMID:19738041 NCBI chr 7:48,717,518...48,873,492 JBrowse link
G LOC110255229 peroxisomal sarcosine oxidase involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr12:45,256,806...45,270,755
Ensembl chr12:45,257,188...45,322,767
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,819,612...68,853,067
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:11730351 RGD:1601423 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:11730351 PMID:21121936 RGD:1601423 RGD:7207080 NCBI chr14:54,546,978...54,652,780
Ensembl chr14:54,546,981...54,652,759
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
G TYMS thymidylate synthetase ISO 5-formyltetrahydrofolate RGD PMID:7503782 RGD:5133451 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,640,031...105,660,601
JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
GO_Central
UniProt
Ensembl
PMID:21873635 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:268,281,298...268,309,397
Ensembl chr 1:268,287,729...268,309,411
JBrowse link
tetrahydrofolylpolyglutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GGH gamma-glutamyl hydrolase involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 4:70,996,730...71,020,513
Ensembl chr 4:70,961,465...71,021,839
JBrowse link
G TTPA alpha tocopherol transfer protein involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 4:70,960,580...70,980,883
Ensembl chr 4:70,961,465...71,021,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16975
    cellular process 16218
      cellular metabolic process 9655
        cellular modified amino acid metabolic process 184
          folic acid-containing compound metabolic process 30
            dihydrofolate metabolic process + 2
            folic acid metabolic process + 9
            folic acid-containing compound biosynthetic process + 7
            folic acid-containing compound catabolic process + 5
            tetrahydrofolate metabolic process + 23
            tetrahydrofolylpolyglutamate metabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 16975
    cellular process 16218
      cellular metabolic process 9655
        cellular aromatic compound metabolic process 5211
          pteridine-containing compound metabolic process 35
            folic acid-containing compound metabolic process 30
              dihydrofolate metabolic process + 2
              folic acid metabolic process + 9
              folic acid-containing compound biosynthetic process + 7
              folic acid-containing compound catabolic process + 5
              tetrahydrofolate metabolic process + 23
              tetrahydrofolylpolyglutamate metabolic process + 3
paths to the root