Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:folic acid-containing compound metabolic process
go back to main search page
Accession:GO:0006760 term browser browse the term
Definition:The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
Synonyms:exact_synonym: folate and derivative metabolic process;   folate and derivative metabolism;   folate-containing compound metabolic process;   folate-containing compound metabolism;   folic acid and derivative metabolic process;   folic acid and derivative metabolism;   folic acid-containing compound metabolism;   vitamin B9 and derivative metabolic process;   vitamin B9 and derivative metabolism;   vitamin M and derivative metabolic process;   vitamin M and derivative metabolism



show annotations for term's descendants           Sort by:
 
folic acid-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:98,921,986...98,933,542
Ensembl chr 9:127,593,592...127,604,200
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:148,679,587...148,919,002
Ensembl chr 6:153,390,498...153,619,884
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA UniProt GO_REF:0000117 NCBI chr2A:74,270,161...74,285,790
Ensembl chr2A:75,777,028...75,792,699
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IEA UniProt GO_REF:0000117 NCBI chr 4:49,889,607...50,034,860
Ensembl chr 4:55,722,237...55,867,117
JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:148,679,587...148,919,002
Ensembl chr 6:153,390,498...153,619,884
JBrowse link
10-formyltetrahydrofolate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase acts_upstream_of_positive_effect ISO (PMID:19933275), (PMID:21238436) UniProt PMID:19933275 PMID:21238436 NCBI chr11:100,969,185...100,990,296
Ensembl chr11:104,452,913...104,474,063
JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:123,166,630...123,244,257
Ensembl chr 3:130,484,862...130,562,934
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA UniProt
InterPro
Ensembl
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr12:102,596,881...102,661,617
Ensembl chr12:105,997,045...106,056,607
JBrowse link
10-formyltetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chr 4:49,889,607...50,034,860
Ensembl chr 4:55,722,237...55,867,117
JBrowse link
dihydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:8948466 RGD:5144056 NCBI chr2B:102,574,700...102,612,492
Ensembl chr2B:221,159,439...221,197,360
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO
IEA
RGD
Ensembl
PMID:3970530 PMID:11502523 GO_REF:0000107 RGD:1298877 RGD:2300196 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in ISO PMID:1848231 UniProt PMID:1848231 RGD:632027 NCBI chr 3:123,166,630...123,244,257
Ensembl chr 3:130,484,862...130,562,934
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:102,596,881...102,661,617
Ensembl chr12:105,997,045...106,056,607
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO PMID:20424322 BHF-UCL PMID:20424322 RGD:10054082 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G FOLR1 folate receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2669340|PMID:12854656) MGI
Ensembl
PMID:12854656 GO_REF:0000107 MGI:2669340 NCBI chr11:67,268,721...67,275,498
Ensembl chr11:70,492,039...70,498,665
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
folic acid-containing compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000117 NCBI chr 9:98,921,986...98,933,542
Ensembl chr 9:127,593,592...127,604,200
JBrowse link
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:7057182 RGD:2301991 NCBI chr2B:102,574,700...102,612,492
Ensembl chr2B:221,159,439...221,197,360
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO
IEA
RGD
Ensembl
UniProt
InterPro
PMID:11502523 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 RGD:1298877 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO RGD PMID:4078017 RGD:2301990 NCBI chr21:19,871,656...19,909,893
Ensembl chr21:33,244,457...33,282,331
JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:35,428,676...35,489,359
Ensembl chr14:53,706,723...53,767,393
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 5:36,241,341...36,313,995
Ensembl chr 5:36,732,005...36,805,883
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase involved_in IEA UniProt GO_REF:0000041 NCBI chr21:32,481,042...32,501,932
Ensembl chr21:45,734,825...45,753,400
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA UniProt GO_REF:0000041 NCBI chr 6:148,679,587...148,919,002
Ensembl chr 6:153,390,498...153,619,884
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in ISO PMID:24733394 RGD
UniProt
PMID:21163947 PMID:24733394 RGD:150521648 RGD:7244288 NCBI chr 4:49,889,607...50,034,860
Ensembl chr 4:55,722,237...55,867,117
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IEA UniProt
Ensembl
GO_REF:0000041 GO_REF:0000107 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 9:104,786,774...104,864,480
Ensembl chr 9:133,398,806...133,473,642
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA UniProt
InterPro
Ensembl
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr12:31,692,451...31,697,727
Ensembl chr12:31,944,785...31,950,138
JBrowse link
G TYMS thymidylate synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:13,653,085...13,668,478
Ensembl chr18:17,295,182...17,310,320
JBrowse link
tetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G DHFR2 dihydrofolate reductase 2 involved_in ISO (PMID:21876184) UniProt PMID:21876184 NCBI chr 3:91,125,295...91,128,378 JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,270,161...74,285,790
Ensembl chr2A:75,777,028...75,792,699
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:11730351 RGD:1601423 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:11730351 PMID:21121936 RGD:1601423 RGD:7207080 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946
JBrowse link
G PIPOX pipecolic acid and sarcosine oxidase involved_in IEA InterPro GO_REF:0000002 NCBI chr17:27,717,083...27,820,776
Ensembl chr17:28,225,831...28,240,210
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,692,451...31,697,727
Ensembl chr12:31,944,785...31,950,138
JBrowse link
G TYMS thymidylate synthetase ISO 5-formyltetrahydrofolate RGD PMID:7503782 RGD:5133451 NCBI chr18:13,653,085...13,668,478
Ensembl chr18:17,295,182...17,310,320
JBrowse link
tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FPGS folylpolyglutamate synthase involved_in IEA UniProt
Ensembl
GO_REF:0000041 GO_REF:0000107 NCBI chr 9:98,921,986...98,933,542
Ensembl chr 9:127,593,592...127,604,200
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15229
    cellular process 14344
      cellular metabolic process 8986
        cellular modified amino acid metabolic process 185
          folic acid-containing compound metabolic process 24
            dihydrofolate metabolic process + 2
            folic acid metabolic process + 6
            folic acid-containing compound biosynthetic process + 7
            folic acid-containing compound catabolic process + 3
            tetrahydrofolate metabolic process + 21
            tetrahydrofolylpolyglutamate metabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 15229
    cellular process 14344
      cellular metabolic process 8986
        cellular aromatic compound metabolic process 4864
          pteridine-containing compound metabolic process 29
            folic acid-containing compound metabolic process 24
              dihydrofolate metabolic process + 2
              folic acid metabolic process + 6
              folic acid-containing compound biosynthetic process + 7
              folic acid-containing compound catabolic process + 3
              tetrahydrofolate metabolic process + 21
              tetrahydrofolylpolyglutamate metabolic process + 1
paths to the root