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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquinone biosynthetic process
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Accession:GO:0006744 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
Synonyms:exact_synonym: coenzyme Q biosynthesis;   coenzyme Q biosynthetic process;   ubiquinone anabolism;   ubiquinone biosynthesis;   ubiquinone formation;   ubiquinone synthesis
 narrow_synonym: coenzyme Q10 biosynthesis;   coenzyme Q10 biosynthetic process;   coenzyme Q6 biosynthesis;   coenzyme Q6 biosynthetic process;   coenzyme Q8 biosynthesis;   coenzyme Q8 biosynthetic process;   coenzyme Q9 biosynthesis;   coenzyme Q9 biosynthetic process
 xref: MetaCyc:UBISYN-PWY



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ubiquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq10a coenzyme Q10A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161
JBrowse link
G Coq10b coenzyme Q10B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
ISS
GO_REF:0000041
GO_REF:0000033
SGD:S000005324 (PMID:15153069)
GO_REF:0000024
(PMID:15153069), (PMID:16400613), (PMID:17374725), (PMID:27493029)
UniProt
GO_Central
RGD
PMID:15153069 PMID:16400613 PMID:17374725 PMID:27493029 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
JBrowse link
G Coq3 coenzyme Q3 methyltransferase involved_in ISO
IBA
UniProtKB:P27680 (PMID:10777520)
GO_REF:0000033
RGD
GO_Central
PMID:10777520 GO_REF:0000033 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Coq4 coenzyme Q4 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799
JBrowse link
G Coq5 coenzyme Q5, methyltransferase involved_in ISO
IBA
IEA
UniProtKB:P49017 (PMID:25152161)
GO_REF:0000033
GO_REF:0000041
RGD
GO_Central
UniProt
PMID:25152161 GO_REF:0000033 GO_REF:0000041 NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848
JBrowse link
G Coq6 coenzyme Q6 monooxygenase involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
GO_REF:0000043
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 NCBI chr 6:104,007,814...104,019,888
Ensembl chr 6:104,007,872...104,024,657
JBrowse link
G Coq7 coenzyme Q7, hydroxylase involved_in
NOT|acts_upstream_of_or_within
IGI
ISO
IBA
ISS
IEA
(PMID:28409910)
GO_REF:0000033
GO_REF:0000024
MGI:2157003 (MGI:4359329|PMID:19478076)
MGI:2157003|MGI:2158322 (MGI:2154585|PMID:11716496), (MGI:2154595|PMID:11585841)
GO_REF:0000041
RGD
GO_Central
UniProt
PMID:11585841 PMID:11716496 PMID:19478076 PMID:28409910 PMID:8660658 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 MGI:2154585 MGI:2154595 MGI:4359329, RGD:69815 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
JBrowse link
G Coq8a coenzyme Q8A involved_in IEA
IBA
ISS
ISO
GO_REF:0000041
GO_REF:0000033
GO_REF:0000024
(PMID:25498144), (PMID:27499294)
UniProt
GO_Central
RGD
PMID:25498144 PMID:27499294 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
JBrowse link
G Coq8b coenzyme Q8B involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
(PMID:27499294)
UniProt
TreeGrafter
GO_Central
RGD
PMID:27499294 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:82,525,578...82,549,182
Ensembl chr 1:82,526,568...82,549,180
JBrowse link
G Coq9 coenzyme Q9 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
ISS
GO_REF:0000041
GO_REF:0000033
(MGI:5609189|PMID:25339443)
MGI:5473628 (MGI:5468078|PMID:23255162)
GO_REF:0000024
UniProt
GO_Central
RGD
PMID:23255162 PMID:25339443 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 MGI:5468078 MGI:5609189 NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949
JBrowse link
G ENSRNOG00000068842 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 2:52,414,697...52,415,415 JBrowse link
G Fdxr ferredoxin reductase involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 involved_in ISO
IBA
(PMID:16262699)
GO_REF:0000033
(MGI:3607849|PMID:16262699)
RGD
GO_Central
PMID:16262699 GO_REF:0000033 MGI:3607849 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 involved_in IEA
IBA
ISO
GO_REF:0000041
GO_REF:0000033
GO_REF:0000118
(MGI:3607849|PMID:16262699)
(PMID:16262699)
UniProt
GO_Central
TreeGrafter
RGD
PMID:16262699 GO_REF:0000033 GO_REF:0000041 GO_REF:0000118 MGI:3607849 NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23374346)
UniProt
RGD
PMID:23374346 GO_REF:0000024 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271
JBrowse link
regulation of ubiquinone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adck2 aarF domain containing kinase 2 involved_in ISO (PMID:31480808)
(MGI:6369566|PMID:31480808)
RGD PMID:31480808 MGI:6369566 NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 involved_in ISO (PMID:30267671) RGD PMID:30267671 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339
JBrowse link
ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq3 coenzyme Q3 methyltransferase IGI RGD PMID:8125303 RGD:69814 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271
JBrowse link
ubiquinone-6 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 4:159,659,242...159,688,034
Ensembl chr 4:159,659,242...159,688,018
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    metabolic process 11737
      cellular metabolic process 10300
        cellular ketone metabolic process 264
          quinone metabolic process 43
            ubiquinone metabolic process 23
              ubiquinone biosynthetic process 20
                negative regulation of ubiquinone biosynthetic process 0
                positive regulation of ubiquinone biosynthetic process 0
                regulation of ubiquinone biosynthetic process + 2
                ubiquinone biosynthetic process from chorismate 0
                ubiquinone biosynthetic process from tyrosine 0
                ubiquinone biosynthetic process via 2-polyprenylphenol 0
                ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate 2
                ubiquinone-6 biosynthetic process 1
paths to the root