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ONTOLOGY REPORT - ANNOTATIONS


Term:NADPH regeneration
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Accession:GO:0006740 term browser browse the term
Definition:A metabolic process that generates a pool of NADPH by the reduction of NADP+.
Synonyms:exact_synonym: reduced NADP regeneration;   reduced nicotinamide adenine dinucleotide phosphate regeneration


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NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:17516514) BHF-UCL PMID:17516514 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,025,257...125,041,033
JBrowse link
G NNT nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chr16:28,157,192...28,248,732
Ensembl chr16:28,157,307...28,250,961
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:2297768) RGD
BHF-UCL
PMID:2297768 PMID:2843500 RGD:1599574 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,025,257...125,041,033
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2668276|PMID:12831846) UniProt
MGI
PMID:12831846 GO_REF:0000041 MGI:2668276 NCBI chr 6:69,666,348...69,700,303
Ensembl chr 6:69,666,600...69,714,463
JBrowse link
G PGD phosphogluconate dehydrogenase involved_in ISS
ISO
IEA
UniProt
RGD
PMID:2843500 GO_REF:0000024 GO_REF:0000041 RGD:1599574 NCBI chr 6:70,675,751...70,692,697
Ensembl chr 6:70,675,815...70,692,679
JBrowse link
G PGLS 6-phosphogluconolactonase involved_in IEA UniProt GO_REF:0000041 NCBI chr 2:60,186,690...60,198,037
Ensembl chr 2:60,164,259...60,197,648
JBrowse link
G RPE ribulose-5-phosphate-3-epimerase involved_in IEA
ISO
InterPro
RGD
PMID:2843500 GO_REF:0000002 RGD:1599574 NCBI chr15:112,723,318...112,748,337 JBrowse link
G RPIA ribose 5-phosphate isomerase A ISO RGD PMID:2843500 RGD:1599574 NCBI chr 3:57,355,973...57,386,948
Ensembl chr 3:57,355,979...57,386,946
JBrowse link
G TALDO1 transaldolase 1 involved_in IEA
ISO
UniProt
RGD
PMID:2843500 GO_REF:0000041 RGD:1599574 NCBI chr 2:464,781...472,836
Ensembl chr 2:435,125...473,744
JBrowse link
G TKT transketolase involved_in ISO
IEA
RGD
Ensembl
PMID:2843500 GO_REF:0000107 RGD:1599574 NCBI chr13:35,348,921...35,377,518
Ensembl chr13:35,348,912...35,377,580
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE ribulose-5-phosphate-3-epimerase involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:3079759 PMID:21873635 RGD:1641816 NCBI chr15:112,723,318...112,748,337 JBrowse link
G RPIA ribose 5-phosphate isomerase A involved_in IEA
ISO
IBA
(PMID:21873635) InterPro
RGD
GO_Central
PMID:3079759 PMID:21873635 GO_REF:0000002 RGD:1641816 NCBI chr 3:57,355,973...57,386,948
Ensembl chr 3:57,355,979...57,386,946
JBrowse link
G SHPK sedoheptulokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,713,224...49,732,319 JBrowse link
G TALDO1 transaldolase 1 ISO RGD PMID:3079759 PMID:8477719 RGD:1641803 RGD:1641816 NCBI chr 2:464,781...472,836
Ensembl chr 2:435,125...473,744
JBrowse link
G TKT transketolase ISO RGD PMID:3079759 PMID:16116031 RGD:1580394 RGD:1641816 NCBI chr13:35,348,921...35,377,518
Ensembl chr13:35,348,912...35,377,580
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO
IEA
RGD
Ensembl
PMID:9794092 GO_REF:0000107 RGD:1641793 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,025,257...125,041,033
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,666,348...69,700,303
Ensembl chr 6:69,666,600...69,714,463
JBrowse link
G PGD phosphogluconate dehydrogenase involved_in IBA
ISO
IEA
(PMID:21873635) GO_Central
RGD
Ensembl
PMID:9794092 PMID:21873635 GO_REF:0000107 RGD:1641793 NCBI chr 6:70,675,751...70,692,697
Ensembl chr 6:70,675,815...70,692,679
JBrowse link
G PGLS 6-phosphogluconolactonase ISO RGD PMID:971315 RGD:2311501 NCBI chr 2:60,186,690...60,198,037
Ensembl chr 2:60,164,259...60,197,648
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 9:133,231,451...133,278,396
Ensembl chr 9:133,231,451...133,278,396
JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,822,782...108,832,818
Ensembl chr14:108,822,812...108,833,058
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10421
      NADP metabolic process 36
        NADPH regeneration 14
          pentose-phosphate shunt + 13
          pentose-phosphate shunt, oxidative branch 4
          photosynthetic NADP+ reduction 0
Path 2
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10421
      cellular metabolic process 9468
        generation of precursor metabolites and energy 421
          NADPH regeneration 14
            pentose-phosphate shunt + 13
            pentose-phosphate shunt, oxidative branch 4
            photosynthetic NADP+ reduction 0
paths to the root