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ONTOLOGY REPORT - ANNOTATIONS

Term:NADPH regeneration
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Accession:GO:0006740 term browser browse the term
Definition:A metabolic process that generates a pool of NADPH by the reduction of NADP+.
Synonyms:exact_synonym: reduced NADP regeneration;   reduced nicotinamide adenine dinucleotide phosphate regeneration


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NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:53,748,585...53,794,777
Ensembl chr 7:53,748,653...53,794,706 		JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:79,492,672...79,558,702
Ensembl chr 5:79,492,750...79,558,701 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G NNT nicotinamide nucleotide transhydrogenase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:22198343 GO_REF:0000118 RGD:13513982 NCBI chr16:28,157,192...28,248,732
Ensembl chr16:28,157,318...28,250,961 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:243,127,870...243,141,504
Ensembl chr 1:243,110,585...243,141,418 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta ISO RGD PMID:31709908 RGD:329901803 NCBI chr14:41,621,574...41,739,916
Ensembl chr14:41,621,574...41,739,916 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO
IEA		 RGD
UniProt
Ensembl		 PMID:2843500 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 RGD:1599574 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12831846) InterPro
MGI
UniProt		 PMID:12831846 GO_REF:0000002 GO_REF:0000041 GO_REF:0000117 NCBI chr 6:69,666,348...69,700,303
Ensembl chr 6:69,666,601...69,700,298 		JBrowse link
G PGD phosphogluconate dehydrogenase involved_in ISO
IEA
ISS		 RGD
UniProt
InterPro		 PMID:2843500 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 RGD:1599574 NCBI chr 6:70,675,751...70,692,697
Ensembl chr 6:70,675,815...70,692,679 		JBrowse link
G PGLS 6-phosphogluconolactonase involved_in IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr 2:60,186,690...60,198,037
Ensembl chr 2:60,187,747...60,197,648 		JBrowse link
G PRPS1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (PMID:24855946) MGI PMID:24855946 NCBI chr  X:88,074,861...88,101,925
Ensembl chr  X:88,074,965...88,101,910 		JBrowse link
G PRPS2 phosphoribosyl pyrophosphate synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:9,505,034...9,531,044
Ensembl chr  X:9,503,953...9,530,086 		JBrowse link
G RBKS ribokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:111,328,758...111,426,173
Ensembl chr 3:111,328,750...111,426,908 		JBrowse link
G RPE ribulose-5-phosphate-3-epimerase involved_in ISO
IEA		 RGD
InterPro		 PMID:2843500 GO_REF:0000002 RGD:1599574 NCBI chr15:112,723,318...112,748,337 JBrowse link
G RPIA ribose 5-phosphate isomerase A involved_in ISO
IEA		 RGD
Ensembl
UniProt		 PMID:2843500 GO_REF:0000041 GO_REF:0000107 RGD:1599574 NCBI chr 3:57,355,973...57,386,948
Ensembl chr 3:57,355,975...57,386,939 		JBrowse link
G TALDO1 transaldolase 1 involved_in ISO
ISS
IEA		 RGD
UniProt
InterPro		 PMID:2843500 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 RGD:1599574 NCBI chr 2:464,781...472,836
Ensembl chr 2:464,728...472,835 		JBrowse link
G TKT transketolase involved_in ISO
IEA		 RGD
Ensembl		 PMID:2843500 GO_REF:0000107 RGD:1599574 NCBI chr13:35,348,921...35,377,518
Ensembl chr13:35,348,915...35,377,587 		JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE ribulose-5-phosphate-3-epimerase involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter		 PMID:3079759 GO_REF:0000033 GO_REF:0000118 RGD:1641816 NCBI chr15:112,723,318...112,748,337 JBrowse link
G RPIA ribose 5-phosphate isomerase A involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
InterPro		 PMID:3079759 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 RGD:1641816 NCBI chr 3:57,355,973...57,386,948
Ensembl chr 3:57,355,975...57,386,939 		JBrowse link
G SHPK sedoheptulokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,713,224...49,732,319
Ensembl chr12:49,712,177...49,732,246 		JBrowse link
G TALDO1 transaldolase 1 involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central		 PMID:3079759 PMID:8477719 GO_REF:0000033 GO_REF:0000118 RGD:1641803 RGD:1641816 NCBI chr 2:464,781...472,836
Ensembl chr 2:464,728...472,835 		JBrowse link
G TKT transketolase involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter		 PMID:3079759 PMID:16116031 GO_REF:0000033 GO_REF:0000118 RGD:1580394 RGD:1641816 NCBI chr13:35,348,921...35,377,518
Ensembl chr13:35,348,915...35,377,587 		JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:9794092 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1641793 NCBI chr  X:125,029,147...125,041,040
Ensembl chr  X:125,029,150...125,041,040 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:69,666,348...69,700,303
Ensembl chr 6:69,666,601...69,700,298 		JBrowse link
G PGD phosphogluconate dehydrogenase involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
Ensembl		 PMID:9794092 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1641793 NCBI chr 6:70,675,751...70,692,697
Ensembl chr 6:70,675,815...70,692,679 		JBrowse link
G PGLS 6-phosphogluconolactonase involved_in ISO
IBA		 RGD
GO_Central		 PMID:971315 GO_REF:0000033 RGD:2311501 NCBI chr 2:60,186,690...60,198,037
Ensembl chr 2:60,187,747...60,197,648 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 9:133,231,451...133,278,396
Ensembl chr 9:133,231,451...133,278,396 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,822,782...108,832,818
Ensembl chr14:108,822,812...108,833,058 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      cellular metabolic process 8632
        generation of precursor metabolites and energy 447
          NADPH regeneration 21
            pentose-phosphate shunt + 18
            pentose-phosphate shunt, oxidative branch 4
            photosynthetic NADP+ reduction 0
Path 2
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      organic substance metabolic process 9930
        organic cyclic compound metabolic process 5601
          nucleobase-containing compound metabolic process 5148
            nucleobase-containing small molecule metabolic process 603
              nucleoside phosphate metabolic process 533
                nucleotide metabolic process 526
                  pyridine nucleotide metabolic process 169
                    nicotinamide nucleotide metabolic process 169
                      NADP metabolic process 49
                        NADPH regeneration 21
                          pentose-phosphate shunt + 18
                          pentose-phosphate shunt, oxidative branch 4
                          photosynthetic NADP+ reduction 0
paths to the root