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ONTOLOGY REPORT - ANNOTATIONS


Term:NADPH regeneration
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Accession:GO:0006740 term browser browse the term
Definition:A metabolic process that generates a pool of NADPH by the reduction of NADP+.
Synonyms:exact_synonym: reduced NADP regeneration;   reduced nicotinamide adenine dinucleotide phosphate regeneration


show annotations for term's descendants           Sort by:
 
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in IMP (PMID:17516514) BHF-UCL PMID:17516514 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G NNT nicotinamide nucleotide transhydrogenase involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:21873635 PMID:22198343 RGD:13513982 NCBI chr 5:43,601,092...43,707,396
Ensembl chr 5:43,602,692...43,707,405
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in IMP (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DERA deoxyribose-phosphate aldolase involved_in TAS Reactome Reactome:R-HSA-71336 NCBI chr12:15,911,332...16,037,381
Ensembl chr12:15,911,302...16,037,381
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IEA
ISO
IDA
(PMID:2297768) UniProt
RGD
BHF-UCL
PMID:2297768 PMID:2843500 GO_REF:0000041 RGD:1599574 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase acts_upstream_of_or_within ISO (MGI:2668276|PMID:12831846) MGI PMID:12831846 MGI:2668276 NCBI chr 1:9,234,767...9,271,337
Ensembl chr 1:9,234,774...9,271,337
JBrowse link
G PGD phosphogluconate dehydrogenase involved_in IEA
ISO
ISS
UniProt
RGD
PMID:2843500 GO_REF:0000024 GO_REF:0000041 RGD:1599574 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
JBrowse link
G PGLS 6-phosphogluconolactonase involved_in IEA
TAS
IDA
(PMID:10518023) UniProt
Reactome
PMID:10518023 GO_REF:0000041 Reactome:R-HSA-71336 NCBI chr19:17,511,649...17,521,291
Ensembl chr19:17,511,636...17,521,288
JBrowse link
G RBKS ribokinase involved_in TAS Reactome Reactome:R-HSA-71336 NCBI chr 2:27,781,379...27,890,387
Ensembl chr 2:27,781,379...27,890,681
JBrowse link
G RPE ribulose-5-phosphate-3-epimerase involved_in IDA
ISO
IEA
(PMID:20923965) UniProt
RGD
InterPro
PMID:2843500 PMID:20923965 GO_REF:0000002 RGD:1599574 NCBI chr 2:210,002,628...210,023,363
Ensembl chr 2:210,002,565...210,022,260
JBrowse link
G RPIA ribose 5-phosphate isomerase A involved_in TAS
ISO
Reactome
RGD
PMID:2843500 RGD:1599574 Reactome:R-HSA-71336 NCBI chr 2:88,691,673...88,750,929
Ensembl chr 2:88,691,673...88,750,929
JBrowse link
G SHPK sedoheptulokinase involved_in TAS Reactome Reactome:R-HSA-71336 NCBI chr17:3,608,240...3,636,250
Ensembl chr17:3,608,240...3,636,250
JBrowse link
G TALDO1 transaldolase 1 involved_in IEA
ISO
UniProt
RGD
PMID:2843500 GO_REF:0000041 RGD:1599574 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
JBrowse link
G TKT transketolase involved_in IDA
ISO
(PMID:20667822) UniProt
RGD
PMID:2843500 PMID:20667822 RGD:1599574 NCBI chr 3:53,224,712...53,256,052
Ensembl chr 3:53,224,712...53,256,052
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE ribulose-5-phosphate-3-epimerase involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:3079759 PMID:21873635 RGD:1641816 NCBI chr 2:210,002,628...210,023,363
Ensembl chr 2:210,002,565...210,022,260
JBrowse link
G RPEL1 ribulose-5-phosphate-3-epimerase like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:103,245,887...103,248,016
Ensembl chr10:103,245,887...103,248,016
JBrowse link
G RPIA ribose 5-phosphate isomerase A involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:3079759 PMID:21873635 RGD:1641816 NCBI chr 2:88,691,673...88,750,929
Ensembl chr 2:88,691,673...88,750,929
JBrowse link
G SHPK sedoheptulokinase involved_in ISS UniProt GO_REF:0000024 NCBI chr17:3,608,240...3,636,250
Ensembl chr17:3,608,240...3,636,250
JBrowse link
G TALDO1 transaldolase 1 involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:3079759 PMID:8477719 PMID:21873635 RGD:1641803 RGD:1641816 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
JBrowse link
G TKT transketolase involved_in IBA
ISO
NAS
(PMID:21873635)
(PMID:9357955)
GO_Central
RGD
UniProt
PMID:3079759 PMID:9357955 PMID:16116031 PMID:21873635 RGD:1580394 RGD:1641816 NCBI chr 3:53,224,712...53,256,052
Ensembl chr 3:53,224,712...53,256,052
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in IMP
ISO
(PMID:2420826) BHF-UCL
RGD
PMID:2420826 PMID:9794092 RGD:1641793 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IMP (PMID:18628520), (PMID:23132696) UniProt PMID:18628520 PMID:23132696 NCBI chr 1:9,234,767...9,271,337
Ensembl chr 1:9,234,774...9,271,337
JBrowse link
G PGD phosphogluconate dehydrogenase involved_in IDA
ISO
IBA
(PMID:3858849)
(PMID:21873635)
UniProt
RGD
GO_Central
PMID:3858849 PMID:9794092 PMID:21873635 RGD:1641793 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
JBrowse link
G PGLS 6-phosphogluconolactonase involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:971315 PMID:21873635 RGD:2311501 NCBI chr19:17,511,649...17,521,291
Ensembl chr19:17,511,636...17,521,288
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in IDA (PMID:12189148) UniProt PMID:12189148 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IMP
IBA
(PMID:25928429)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:25928429 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      NADP metabolic process 41
        NADPH regeneration 17
          pentose-phosphate shunt + 16
          pentose-phosphate shunt, oxidative branch 4
          photosynthetic NADP+ reduction 0
Path 2
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      cellular metabolic process 10809
        generation of precursor metabolites and energy 534
          NADPH regeneration 17
            pentose-phosphate shunt + 16
            pentose-phosphate shunt, oxidative branch 4
            photosynthetic NADP+ reduction 0
paths to the root