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ONTOLOGY REPORT - ANNOTATIONS


Term:NADPH regeneration
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Accession:GO:0006740 term browser browse the term
Definition:A metabolic process that generates a pool of NADPH by the reduction of NADP+.
Synonyms:exact_synonym: reduced NADP regeneration;   reduced nicotinamide adenine dinucleotide phosphate regeneration


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NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:17516514) BHF-UCL PMID:17516514 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G NNT nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chr 5:66,662,249...66,772,352
Ensembl chr 5:71,719,257...71,823,242
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:2297768) RGD
BHF-UCL
PMID:2297768 PMID:2843500 RGD:1599574 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase acts_upstream_of_or_within ISO (MGI:2668276|PMID:12831846) MGI PMID:12831846 MGI:2668276 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631
JBrowse link
G PGD phosphogluconate dehydrogenase ISO RGD PMID:2843500 RGD:1599574 NCBI chr 1:9,159,412...9,180,740
Ensembl chr 1:10,385,087...10,408,078
JBrowse link
G PGLS 6-phosphogluconolactonase involved_in ISO (PMID:10518023) UniProt PMID:10518023 NCBI chr19:16,998,851...17,008,558
Ensembl chr19:17,971,544...17,980,431
JBrowse link
G RPE ribulose-5-phosphate-3-epimerase involved_in ISO (PMID:20923965) RGD
UniProt
PMID:2843500 PMID:20923965 RGD:1599574 NCBI chr2B:97,260,348...97,282,397 JBrowse link
G RPIA ribose 5-phosphate isomerase A ISO RGD PMID:2843500 RGD:1599574 NCBI chr2A:87,823,741...87,880,061
Ensembl chr2A:89,731,335...89,787,512
JBrowse link
G TALDO1 transaldolase 1 ISO RGD PMID:2843500 RGD:1599574 NCBI chr11:764,864...782,548
Ensembl chr11:809,751...826,744
JBrowse link
G TKT transketolase involved_in ISO (PMID:20667822) RGD
UniProt
PMID:2843500 PMID:20667822 RGD:1599574 NCBI chr 3:53,168,426...53,199,003
Ensembl chr 3:54,389,549...54,420,704
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE ribulose-5-phosphate-3-epimerase ISO RGD PMID:3079759 RGD:1641816 NCBI chr2B:97,260,348...97,282,397 JBrowse link
G RPIA ribose 5-phosphate isomerase A ISO RGD PMID:3079759 RGD:1641816 NCBI chr2A:87,823,741...87,880,061
Ensembl chr2A:89,731,335...89,787,512
JBrowse link
G SHPK sedoheptulokinase involved_in ISO (MGI:5428058|PMID:22682222) UniProt PMID:22682222 MGI:5428058 NCBI chr17:3,657,764...3,686,791 JBrowse link
G TALDO1 transaldolase 1 ISO RGD PMID:3079759 PMID:8477719 RGD:1641803 RGD:1641816 NCBI chr11:764,864...782,548
Ensembl chr11:809,751...826,744
JBrowse link
G TKT transketolase ISO RGD PMID:3079759 PMID:16116031 RGD:1580394 RGD:1641816 NCBI chr 3:53,168,426...53,199,003
Ensembl chr 3:54,389,549...54,420,704
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:2420826) RGD
BHF-UCL
PMID:2420826 PMID:9794092 RGD:1641793 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in ISO (PMID:18628520), (PMID:23132696) UniProt PMID:18628520 PMID:23132696 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631
JBrowse link
G PGD phosphogluconate dehydrogenase involved_in ISO (PMID:3858849) RGD
UniProt
PMID:3858849 PMID:9794092 RGD:1641793 NCBI chr 1:9,159,412...9,180,740
Ensembl chr 1:10,385,087...10,408,078
JBrowse link
G PGLS 6-phosphogluconolactonase ISO RGD PMID:971315 RGD:2311501 NCBI chr19:16,998,851...17,008,558
Ensembl chr19:17,971,544...17,980,431
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 1:185,262,599...185,311,417
Ensembl chr 1:190,086,449...190,116,765
JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chr10:94,048,829...94,056,082
Ensembl chr10:97,542,558...97,549,867
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) UniProt PMID:25928429 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    metabolic process 7931
      NADP metabolic process 34
        NADPH regeneration 14
          pentose-phosphate shunt + 13
          pentose-phosphate shunt, oxidative branch 4
          photosynthetic NADP+ reduction 0
Path 2
Term Annotations click to browse term
  biological_process 12657
    metabolic process 7931
      cellular metabolic process 7253
        generation of precursor metabolites and energy 336
          NADPH regeneration 14
            pentose-phosphate shunt + 13
            pentose-phosphate shunt, oxidative branch 4
            photosynthetic NADP+ reduction 0
paths to the root