Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:NADPH regeneration
go back to main search page
Accession:GO:0006740 term browser browse the term
Definition:A metabolic process that generates a pool of NADPH by the reduction of NADP+.
Synonyms:exact_synonym: reduced NADP regeneration;   reduced nicotinamide adenine dinucleotide phosphate regeneration


show annotations for term's descendants           Sort by:
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in ISO
IDA		 (PMID:19933275)
PMID:1848231		 RGD PMID:19933275 PMID:1848231 RGD:632027 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO (PMID:21238436)
(MGI:6489626|PMID:33168096)		 RGD PMID:21238436 PMID:33168096 MGI:6489626 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:17516514) RGD PMID:17516514 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:22198343 PMID:21873635 RGD:13513982, RGD:13792537 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) RGD PMID:21336310 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in IDA
ISO		 (PMID:2297768) RGD PMID:2297768 PMID:2843500 RGD:1599574 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) acts_upstream_of_or_within ISO (MGI:2668276|PMID:12831846) RGD PMID:12831846 MGI:2668276 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
G Kif1b kinesin family member 1B involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in IDA
IEA
ISS		 GO_REF:0000041
GO_REF:0000024		 UniProt
RGD		 PMID:2843500 GO_REF:0000024 GO_REF:0000041, RGD:1599574 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgls 6-phosphogluconolactonase involved_in ISO
IEA		 (PMID:10518023)
GO_REF:0000041		 RGD
UniProt		 PMID:10518023 GO_REF:0000041 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (MGI:5602900|PMID:24855946) RGD PMID:24855946 MGI:5602900 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 involved_in ISO (MGI:5602900|PMID:24855946) RGD PMID:24855946 MGI:5602900 NCBI chr  X:26,975,915...27,013,184
Ensembl chr  X:26,976,061...27,013,181 		JBrowse link
G Rbks ribokinase involved_in ISO (MGI:7261130|PMID:13405914) RGD PMID:13405914 MGI:7261130 NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290 		JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase involved_in IDA
ISO		 (MGI:7257768|PMID:5360673)
(PMID:20923965)		 RGD PMID:5360673 PMID:20923965 PMID:2843500 MGI:7257768, RGD:1599574 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591 		JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in IDA
ISO		 (MGI:7257768|PMID:5360673) RGD PMID:5360673 PMID:2843500 MGI:7257768, RGD:1599574 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355 		JBrowse link
G Taldo1 transaldolase 1 involved_in IDA
IEA
ISO		 GO_REF:0000041
(MGI:3851036|PMID:19436114), (MGI:7257768|PMID:5360673), (MGI:7261130|PMID:13405914)		 UniProt
RGD		 PMID:5360673 PMID:13405914 PMID:19436114 PMID:2843500 GO_REF:0000041 MGI:3851036 MGI:7257768 MGI:7261130, RGD:1599574 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tkt transketolase involved_in IDA
IEA
ISO		 GO_REF:0000107
(MGI:7257768|PMID:5360673), (MGI:7261130|PMID:13405914)
(PMID:20667822)		 Ensembl
RGD		 PMID:5360673 PMID:13405914 PMID:20667822 PMID:2843500 GO_REF:0000107 MGI:7257768 MGI:7261130, RGD:1599574 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:3079759 PMID:21873635 RGD:1641816, RGD:13792537 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591 		JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:3079759 PMID:21873635 RGD:1641816, RGD:13792537 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355 		JBrowse link
G Shpk sedoheptulokinase involved_in ISO (MGI:5428058|PMID:22682222) RGD PMID:22682222 MGI:5428058 NCBI chr10:57,817,551...57,841,981
Ensembl chr10:57,817,629...57,841,980 		JBrowse link
G Taldo1 transaldolase 1 involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:8477719 PMID:21873635 PMID:3079759 RGD:1641803, RGD:13792537, RGD:1641816 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tkt transketolase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:16116031 PMID:21873635 PMID:3079759 RGD:1580394, RGD:13792537, RGD:1641816 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in IMP
IBA
ISO		 PMID:21873635
MGI:2182739 (MGI:5446538|PMID:22829586), (MGI:7257767|PMID:12466018)
(PMID:2420826)		 RGD PMID:2420826 PMID:12466018 PMID:22829586 PMID:9794092 PMID:21873635 MGI:5446538 MGI:7257767, RGD:1641793, RGD:13792537 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO
IBA		 (PMID:18628520), (PMID:23132696)
PMID:21873635		 RGD PMID:18628520 PMID:23132696 PMID:21873635 RGD:13792537 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in IMP
IBA
ISO		 PMID:21873635
(MGI:7257767|PMID:12466018), (MGI:7257768|PMID:5360673), (MGI:7257880|PMID:7496990)
(PMID:3858849)		 RGD PMID:3858849 PMID:5360673 PMID:7496990 PMID:12466018 PMID:9794092 More... MGI:7257767 MGI:7257768 MGI:7257880, RGD:1641793, RGD:13792537 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgls 6-phosphogluconolactonase involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:971315 PMID:21873635 RGD:2311501, RGD:13792537 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (MGI:5574521|PMID:24872551) RGD PMID:24872551 MGI:5574521 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:16234247 RGD:1625062 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) RGD PMID:12189148 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) RGD PMID:25928429 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      cellular metabolic process 9535
        generation of precursor metabolites and energy 441
          NADPH regeneration 20
            pentose-phosphate shunt + 17
            pentose-phosphate shunt, oxidative branch 4
            photosynthetic NADP+ reduction 0
Path 2
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      organic substance metabolic process 11599
        organic cyclic compound metabolic process 6090
          nucleobase-containing compound metabolic process 5616
            nucleobase-containing small molecule metabolic process 569
              nucleoside phosphate metabolic process 497
                nucleotide metabolic process 486
                  pyridine nucleotide metabolic process 79
                    nicotinamide nucleotide metabolic process 79
                      NADP metabolic process 46
                        NADPH regeneration 20
                          pentose-phosphate shunt + 17
                          pentose-phosphate shunt, oxidative branch 4
                          photosynthetic NADP+ reduction 0
paths to the root