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ONTOLOGY REPORT - ANNOTATIONS


Term:NADP metabolic process
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Accession:GO:0006739 term browser browse the term
Definition:The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
Synonyms:exact_synonym: NADP metabolism;   NADPH metabolic process;   NADPH metabolism;   nicotinamide adenine dinucleotide phosphate metabolic process;   nicotinamide adenine dinucleotide phosphate metabolism;   oxidized NADP metabolic process;   oxidized NADP metabolism;   oxidized nicotinamide adenine dinucleotide phosphate metabolic process;   oxidized nicotinamide adenine dinucleotide phosphate metabolism;   reduced NADP metabolic process;   reduced NADP metabolism;   reduced nicotinamide adenine dinucleotide phosphate metabolic process;   reduced nicotinamide adenine dinucleotide phosphate metabolism
 related_synonym: NAD phosphorylation and dephosphorylation


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NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5r4 cytochrome b5 reductase 4 involved_in ISO NADPH oxidation RGD
MGI
PMID:11913972 GO_REF:0000096 MGI:4417868 RGD:632262 NCBI chr 9:87,022,008...87,077,774
Ensembl chr 9:87,022,014...87,077,774
JBrowse link
G Dcxr dicarbonyl L-xylulose reductase acts_upstream_of_or_within IDA (MGI:2179664|PMID:11882650) MGI PMID:11882650 MGI:2179664 NCBI chr11:120,724,546...120,727,284
Ensembl chr11:120,725,399...120,727,281
JBrowse link
G Fmo2 flavin containing monooxygenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:162,874,317...162,898,758
Ensembl chr 1:162,874,317...162,898,726
JBrowse link
G G6pd2 glucose-6-phosphate dehydrogenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:61,808,843...61,810,477
Ensembl chr 5:61,808,816...61,811,163
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gck glucokinase acts_upstream_of_or_within IMP (MGI:3691164|PMID:9873043) MGI PMID:9873043 MGI:3691164 NCBI chr11:5,900,816...5,950,081
Ensembl chr11:5,900,820...5,950,081
JBrowse link
G Gm20348 predicted gene, 20348 involved_in ISO (PMID:19349281) UniProt PMID:19349281 NCBI chr12:4,810,475...4,817,155 JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO RGD
MGI
PMID:6813321 GO_REF:0000096 MGI:4417868 RGD:1641956 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
G Idh1 isocitrate dehydrogenase 1 (NADP+), soluble involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:65,158,616...65,186,479
Ensembl chr 1:65,158,616...65,186,500
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Noct nocturnin involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:51,224,447...51,251,654
Ensembl chr 3:51,224,447...51,251,644
JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in ISO RGD
MGI
PMID:6813321 GO_REF:0000096 MGI:4417868 RGD:1641956 NCBI chr 4:149,149,991...149,166,705
Ensembl chr 4:149,149,991...149,166,771
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pdx glucose-6-phosphate dehydrogenase X-linked acts_upstream_of_or_within IMP
IDA
(MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:85983|PMID:9067418)
(MGI:3522057|PMID:15271799)
(MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:54902|PMID:7439685), (MGI:87492|PMID:9169132)
MGI PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial involved_in ISO RGD
MGI
PMID:21641335 GO_REF:0000096 MGI:4417868 RGD:11522736 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Nadk NAD kinase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:21873635 PMID:22550069 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:13703105 NCBI chr 4:155,562,381...155,591,001
Ensembl chr 4:155,562,378...155,591,001
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr15:9,071,260...9,110,496
Ensembl chr15:9,071,260...9,110,891
JBrowse link
NADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (MGI:1351390|PMID:10647999) MGI PMID:10647999 MGI:1351390 NCBI chr 5:134,220,053...134,229,628
Ensembl chr 5:134,220,053...134,229,625
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 acts_upstream_of_or_within ISO (MGI:1351390|PMID:10647999) MGI PMID:10647999 MGI:1351390 NCBI chr 1:152,800,153...152,836,990
Ensembl chr 1:152,800,194...152,836,991
JBrowse link
G Nudt12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:5297790|PMID:12790796)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:12790796 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5297790 MGI:6201960 NCBI chr17:59,000,107...59,013,367
Ensembl chr17:58,999,618...59,013,372
JBrowse link
G Nudt13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 involved_in IDA (MGI:6368098|PMID:28755312) UniProt PMID:28755312 MGI:6368098 NCBI chr14:20,294,679...20,317,584
Ensembl chr14:20,294,697...20,317,578
JBrowse link
G Nudt17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:96,705,892...96,708,916
Ensembl chr 3:96,706,067...96,708,562
JBrowse link
NADPH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 involved_in ISO RGD
MGI
PMID:10525147 GO_REF:0000096 MGI:4417868 RGD:727285 NCBI chr 9:51,943,023...51,963,602
Ensembl chr 9:51,943,306...51,963,556
JBrowse link
G Fdxr ferredoxin reductase involved_in ISO RGD
MGI
PMID:10525147 GO_REF:0000096 MGI:4417868 RGD:727285 NCBI chr11:115,268,024...115,277,101
Ensembl chr11:115,268,024...115,277,050
JBrowse link
G Fmo1 flavin containing monooxygenase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:162,829,561...162,866,610
Ensembl chr 1:162,829,561...162,866,610
JBrowse link
G Fmo2 flavin containing monooxygenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:162,874,317...162,898,758
Ensembl chr 1:162,874,317...162,898,726
JBrowse link
G Fmo5 flavin containing monooxygenase 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:97,609,938...97,655,287
Ensembl chr 3:97,628,804...97,655,282
JBrowse link
G Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 4:152,390,744...152,477,549
Ensembl chr 4:152,390,742...152,477,910
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 involved_in ISO RGD
MGI
PMID:29444417 GO_REF:0000096 MGI:4417868 RGD:25823192 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Prdx5 peroxiredoxin 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:6,906,697...6,910,106
Ensembl chr19:6,906,697...6,910,106
JBrowse link
G Txnrd1 thioredoxin reductase 1 involved_in ISO RGD
MGI
PMID:19054767 GO_REF:0000096 MGI:4417868 RGD:5133716 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd2 glucose-6-phosphate dehydrogenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:61,808,843...61,810,477
Ensembl chr 5:61,808,816...61,811,163
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:21873635 PMID:22198343 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:13513982 NCBI chr13:119,335,527...119,409,257
Ensembl chr13:119,335,448...119,408,997
Ensembl chr13:119,335,448...119,408,997
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trp53 transformation related protein 53 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd2 glucose-6-phosphate dehydrogenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:61,808,843...61,810,477
Ensembl chr 5:61,808,816...61,811,163
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked involved_in ISO MGI
RGD
PMID:2843500 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:1599574 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) acts_upstream_of_or_within IDA (MGI:2668276|PMID:12831846) MGI PMID:12831846 MGI:2668276 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in ISO RGD
MGI
PMID:2843500 GO_REF:0000096 MGI:4417868 RGD:1599574 NCBI chr 4:149,149,991...149,166,705
Ensembl chr 4:149,149,991...149,166,771
JBrowse link
G Pgls 6-phosphogluconolactonase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:71,592,184...71,596,267
Ensembl chr 8:71,592,176...71,601,092
JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase involved_in ISO RGD
MGI
PMID:2843500 GO_REF:0000096 MGI:4417868 RGD:1599574 NCBI chr 1:66,700,797...66,719,805
Ensembl chr 1:66,700,831...66,719,805
JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in ISO RGD
MGI
PMID:2843500 GO_REF:0000096 MGI:4417868 RGD:1599574 NCBI chr 6:70,765,720...70,792,175
Ensembl chr 6:70,765,720...70,792,232
JBrowse link
G Taldo1 transaldolase 1 involved_in ISO RGD
MGI
PMID:2843500 GO_REF:0000096 MGI:4417868 RGD:1599574 NCBI chr 7:141,392,160...141,402,976
Ensembl chr 7:141,392,199...141,402,968
JBrowse link
G Tkt transketolase involved_in ISO MGI
RGD
PMID:2843500 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:1599574 NCBI chr14:30,549,131...30,574,724
Ensembl chr14:30,548,359...30,574,720
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:3079759 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:1641816 NCBI chr 1:66,700,797...66,719,805
Ensembl chr 1:66,700,831...66,719,805
JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:3079759 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:1641816 NCBI chr 6:70,765,720...70,792,175
Ensembl chr 6:70,765,720...70,792,232
JBrowse link
G Shpk sedoheptulokinase involved_in IDA (MGI:5428058|PMID:22682222) UniProt PMID:22682222 MGI:5428058 NCBI chr11:73,199,132...73,224,511
Ensembl chr11:73,199,460...73,224,511
JBrowse link
G Taldo1 transaldolase 1 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:3079759 PMID:8477719 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:1641803 RGD:1641816 NCBI chr 7:141,392,160...141,402,976
Ensembl chr 7:141,392,199...141,402,968
JBrowse link
G Tkt transketolase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:3079759 PMID:16116031 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:1580394 RGD:1641816 NCBI chr14:30,549,131...30,574,724
Ensembl chr14:30,548,359...30,574,720
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd2 glucose-6-phosphate dehydrogenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4417868 MGI:4834177 NCBI chr 5:61,808,843...61,810,477
Ensembl chr 5:61,808,816...61,811,163
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked involved_in ISO MGI
RGD
PMID:9794092 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:1641793 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
RGD
GO_Central
PMID:9794092 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:6201960 RGD:1641793 NCBI chr 4:149,149,991...149,166,705
Ensembl chr 4:149,149,991...149,166,771
JBrowse link
G Pgls 6-phosphogluconolactonase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:971315 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:2311501 NCBI chr 8:71,592,184...71,596,267
Ensembl chr 8:71,592,176...71,601,092
JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:86,581,363...86,695,914
Ensembl chr 9:86,581,371...86,695,953
JBrowse link
G Me2 malic enzyme 2, NAD(+)-dependent, mitochondrial involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:73,764,954...73,815,438
Ensembl chr18:73,769,903...73,815,449
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 involved_in ISO RGD
MGI
PMID:16234247 GO_REF:0000096 MGI:4417868 RGD:1625062 NCBI chr 1:193,221,640...193,264,045
Ensembl chr 1:193,221,634...193,264,075
JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chr19:41,911,871...41,918,665
Ensembl chr19:41,911,923...41,918,660
JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 6:127,085,116...127,109,552
Ensembl chr 6:127,085,116...127,109,557
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    metabolic process 11247
      NADP metabolic process 40
        NADP biosynthetic process 4
        NADP catabolic process 5
        NADPH oxidation 9
        NADPH regeneration + 15
        regulation of NADP metabolic process + 6
paths to the root