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ONTOLOGY REPORT - ANNOTATIONS


Term:NADP metabolic process
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Accession:GO:0006739 term browser browse the term
Definition:The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
Synonyms:exact_synonym: NADP metabolism;   NADPH metabolic process;   NADPH metabolism;   nicotinamide adenine dinucleotide phosphate metabolic process;   nicotinamide adenine dinucleotide phosphate metabolism;   oxidized NADP metabolic process;   oxidized NADP metabolism;   oxidized nicotinamide adenine dinucleotide phosphate metabolic process;   oxidized nicotinamide adenine dinucleotide phosphate metabolism;   reduced NADP metabolic process;   reduced NADP metabolism;   reduced nicotinamide adenine dinucleotide phosphate metabolic process;   reduced nicotinamide adenine dinucleotide phosphate metabolism
 related_synonym: NAD phosphorylation and dephosphorylation


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NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:11744609) BHF-UCL PMID:11744609 NCBI chrNW_004955406:11,851,694...11,875,314
Ensembl chrNW_004955406:11,851,637...11,876,843
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:15858258) UniProt PMID:15858258 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G Gck glucokinase acts_upstream_of_or_within ISO (MGI:3691164|PMID:9873043) MGI PMID:9873043 MGI:3691164 NCBI chrNW_004955456:7,784,269...7,838,260
Ensembl chrNW_004955456:7,783,760...7,842,129
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase ISO RGD PMID:6813321 RGD:1641956 NCBI chrNW_004955486:4,088,354...4,115,077
Ensembl chrNW_004955486:4,022,306...4,115,077
JBrowse link
G LOC102015388 cytochrome b5 reductase 4 ISO NADPH oxidation RGD PMID:11913972 RGD:632262 NCBI chrNW_004955411:11,424,923...11,508,193
Ensembl chrNW_004955411:11,424,505...11,508,193
JBrowse link
G Mdh1 malate dehydrogenase 1 involved_in ISO (PMID:34547241) ComplexPortal PMID:34547241 NCBI chrNW_004955424:20,707,765...20,723,493
Ensembl chrNW_004955424:20,706,058...20,723,493
JBrowse link
G Me1 malic enzyme 1 involved_in ISO (PMID:34547241) ComplexPortal PMID:34547241 NCBI chrNW_004955411:10,938,580...11,084,171
Ensembl chrNW_004955411:10,938,944...11,065,085
JBrowse link
G Noct nocturnin involved_in ISO (PMID:31147539) UniProt PMID:31147539 NCBI chrNW_004955428:4,559,027...4,580,013 JBrowse link
G Pc pyruvate carboxylase involved_in ISO (PMID:34547241) ComplexPortal PMID:34547241 NCBI chrNW_004955422:18,421,100...18,536,591
Ensembl chrNW_004955422:18,420,596...18,536,436
JBrowse link
G Pgd phosphogluconate dehydrogenase ISO RGD PMID:6813321 RGD:1641956 NCBI chrNW_004955486:3,344,705...3,356,906
Ensembl chrNW_004955486:3,343,863...3,357,066
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 involved_in ISO (PMID:19349281) UniProt PMID:19349281 NCBI chrNW_004955469:6,287,442...6,298,944 JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:85983|PMID:9067418)
(MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:54902|PMID:7439685), (MGI:87492|PMID:9169132)
(MGI:3522057|PMID:15271799)
MGI PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO RGD PMID:21641335 RGD:11522736 NCBI chrNW_004955416:15,197,611...15,212,919
Ensembl chrNW_004955416:15,197,366...15,223,363
JBrowse link
G Nadk NAD kinase ISO RGD PMID:22550069 RGD:13703105 NCBI chrNW_004955486:9,191,923...9,217,547
Ensembl chrNW_004955486:9,191,923...9,217,538
JBrowse link
NADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt12 nudix hydrolase 12 involved_in
acts_upstream_of_or_within
ISO (PMID:12790796) MGI PMID:12790796 NCBI chrNW_004955418:10,459,644...10,474,124
Ensembl chrNW_004955418:10,459,638...10,474,124
JBrowse link
G Nudt13 nudix hydrolase 13 involved_in ISO (MGI:6368098|PMID:28755312) UniProt PMID:28755312 MGI:6368098 NCBI chrNW_004955437:18,572,172...18,591,972
Ensembl chrNW_004955437:18,572,416...18,592,279
JBrowse link
NADPH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 ISO RGD PMID:10525147 RGD:727285 NCBI chrNW_004955412:12,280,900...12,312,930
Ensembl chrNW_004955412:12,286,408...12,316,707
JBrowse link
G Fdxr ferredoxin reductase ISO RGD PMID:10525147 RGD:727285 NCBI chrNW_004955553:1,746,759...1,755,316
Ensembl chrNW_004955553:1,746,670...1,755,315
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 involved_in ISO (PMID:15144220) BHF-UCL PMID:15144220 NCBI chrNW_004955406:11,882,656...11,915,875
Ensembl chrNW_004955406:11,881,882...11,916,323
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:15144220), (PMID:9804831) UniProt PMID:9804831 PMID:15144220 NCBI chrNW_004955406:11,851,694...11,875,314
Ensembl chrNW_004955406:11,851,637...11,876,843
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISO (PMID:26771671) UniProt PMID:26771671 NCBI chrNW_004955568:1,225,136...1,247,352
Ensembl chrNW_004955568:1,224,843...1,250,729
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 involved_in ISO PMID:18672894 UniProt PMID:18672894 RGD:10047329 NCBI chrNW_004955486:6,371,212...6,442,888
Ensembl chrNW_004955486:6,369,288...6,442,885
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:29444417 RGD:25823192 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604
JBrowse link
G Prdx5 peroxiredoxin 5 involved_in ISO (PMID:10751410) UniProt PMID:10751410 NCBI chrNW_004955422:20,763,822...20,766,976
Ensembl chrNW_004955422:20,761,495...20,766,976
JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO RGD PMID:19054767 RGD:5133716 NCBI chrNW_004955405:38,863,762...38,928,615
Ensembl chrNW_004955405:38,903,918...38,927,410
JBrowse link
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family member L1 involved_in ISO (PMID:19933275)
PMID:1848231
UniProt PMID:1848231 PMID:19933275 RGD:632027 NCBI chrNW_004955421:21,420,264...21,506,004
Ensembl chrNW_004955421:21,420,147...21,527,037
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family member L2 involved_in ISO (PMID:21238436)
(MGI:6489626|PMID:33168096)
UniProt PMID:21238436 PMID:33168096 MGI:6489626 NCBI chrNW_004955405:39,387,949...39,437,282
Ensembl chrNW_004955405:39,387,527...39,437,322
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:17516514) BHF-UCL PMID:17516514 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chrNW_004955446:18,685,511...18,778,024
Ensembl chrNW_004955446:18,685,516...18,778,024
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:2297768) RGD
BHF-UCL
PMID:2297768 PMID:2843500 RGD:1599574 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase acts_upstream_of_or_within ISO (MGI:2668276|PMID:12831846) MGI PMID:12831846 MGI:2668276 NCBI chrNW_004955486:4,088,354...4,115,077
Ensembl chrNW_004955486:4,022,306...4,115,077
JBrowse link
G Pgd phosphogluconate dehydrogenase ISO RGD PMID:2843500 RGD:1599574 NCBI chrNW_004955486:3,344,705...3,356,906
Ensembl chrNW_004955486:3,343,863...3,357,066
JBrowse link
G Pgls 6-phosphogluconolactonase involved_in ISO (PMID:10518023) UniProt PMID:10518023 NCBI chrNW_004955524:797,439...801,070
Ensembl chrNW_004955524:793,239...801,107
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (MGI:5602900|PMID:24855946) MGI PMID:24855946 MGI:5602900 NCBI chrNW_004955490:8,303,775...8,330,713 JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 involved_in ISO (MGI:5602900|PMID:24855946) MGI PMID:24855946 MGI:5602900 NCBI chrNW_004955544:480,587...512,019
Ensembl chrNW_004955544:478,954...512,614
JBrowse link
G Rbks ribokinase involved_in ISO (MGI:7261130|PMID:13405914) MGI PMID:13405914 MGI:7261130 NCBI chrNW_004955469:9,734,551...9,831,397
Ensembl chrNW_004955469:9,734,563...9,831,127
JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase involved_in ISO (MGI:7257768|PMID:5360673)
(PMID:20923965)
RGD
MGI
UniProt
PMID:2843500 PMID:5360673 PMID:20923965 MGI:7257768 RGD:1599574 NCBI chrNW_004955457:5,425,532...5,441,538 JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in ISO (MGI:7257768|PMID:5360673) RGD
MGI
PMID:2843500 PMID:5360673 MGI:7257768 RGD:1599574 NCBI chrNW_004955424:107,297...135,577
Ensembl chrNW_004955424:106,978...135,612
JBrowse link
G Taldo1 transaldolase 1 involved_in ISO (MGI:3851036|PMID:19436114)
(MGI:7257768|PMID:5360673), (MGI:7261130|PMID:13405914)
RGD
UniProt
MGI
PMID:2843500 PMID:5360673 PMID:13405914 PMID:19436114 MGI:3851036 MGI:7257768 MGI:7261130 RGD:1599574 NCBI chrNW_004955476:11,356,601...11,364,573
Ensembl chrNW_004955476:11,356,603...11,364,259
JBrowse link
G Tkt transketolase involved_in ISO (MGI:7257768|PMID:5360673), (MGI:7261130|PMID:13405914)
(PMID:20667822)
RGD
MGI
UniProt
PMID:2843500 PMID:5360673 PMID:13405914 PMID:20667822 MGI:7257768 MGI:7261130 RGD:1599574 NCBI chrNW_004955430:3,178,830...3,193,241
Ensembl chrNW_004955430:3,178,830...3,193,345
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase ISO RGD PMID:3079759 RGD:1641816 NCBI chrNW_004955457:5,425,532...5,441,538 JBrowse link
G Rpia ribose 5-phosphate isomerase A ISO RGD PMID:3079759 RGD:1641816 NCBI chrNW_004955424:107,297...135,577
Ensembl chrNW_004955424:106,978...135,612
JBrowse link
G Shpk sedoheptulokinase involved_in ISO (MGI:5428058|PMID:22682222) UniProt PMID:22682222 MGI:5428058 NCBI chrNW_004955467:13,169,072...13,209,585
Ensembl chrNW_004955467:13,169,063...13,212,269
JBrowse link
G Taldo1 transaldolase 1 ISO RGD PMID:3079759 PMID:8477719 RGD:1641803 RGD:1641816 NCBI chrNW_004955476:11,356,601...11,364,573
Ensembl chrNW_004955476:11,356,603...11,364,259
JBrowse link
G Tkt transketolase ISO RGD PMID:3079759 PMID:16116031 RGD:1580394 RGD:1641816 NCBI chrNW_004955430:3,178,830...3,193,241
Ensembl chrNW_004955430:3,178,830...3,193,345
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (MGI:7257767|PMID:12466018)
(MGI:5446538|PMID:22829586)
(PMID:2420826)
RGD
MGI
BHF-UCL
PMID:2420826 PMID:9794092 PMID:12466018 PMID:22829586 MGI:5446538 MGI:7257767 RGD:1641793 NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in ISO (PMID:18628520), (PMID:23132696) UniProt PMID:18628520 PMID:23132696 NCBI chrNW_004955486:4,088,354...4,115,077
Ensembl chrNW_004955486:4,022,306...4,115,077
JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in ISO (MGI:7257767|PMID:12466018), (MGI:7257768|PMID:5360673), (MGI:7257880|PMID:7496990)
(PMID:3858849)
RGD
MGI
UniProt
PMID:3858849 PMID:5360673 PMID:7496990 PMID:9794092 PMID:12466018 MGI:7257767 MGI:7257768 MGI:7257880 RGD:1641793 NCBI chrNW_004955486:3,344,705...3,356,906
Ensembl chrNW_004955486:3,343,863...3,357,066
JBrowse link
G Pgls 6-phosphogluconolactonase ISO RGD PMID:971315 RGD:2311501 NCBI chrNW_004955524:797,439...801,070
Ensembl chrNW_004955524:793,239...801,107
JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613
JBrowse link
G Me1 malic enzyme 1 involved_in ISO (PMID:23334421) CACAO PMID:23334421 NCBI chrNW_004955411:10,938,580...11,084,171
Ensembl chrNW_004955411:10,938,944...11,065,085
JBrowse link
G Me2 malic enzyme 2 involved_in ISO (PMID:23334421) CACAO PMID:23334421 NCBI chrNW_004955402:35,816,474...35,894,051 JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chrNW_004955489:2,500,928...2,524,715
Ensembl chrNW_004955489:2,497,680...2,524,805
JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chrNW_004955507:3,562,513...3,571,400
Ensembl chrNW_004955507:3,562,513...3,571,400
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) UniProt PMID:25928429 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12284
    metabolic process 7837
      cellular metabolic process 6669
        cellular aromatic compound metabolic process 4045
          purine-containing compound metabolic process 391
            purine nucleotide metabolic process 362
              NADP metabolic process 41
                NADP biosynthetic process 3
                NADP catabolic process 2
                NADPH oxidation 9
                NADPH regeneration + 19
                regulation of NADP metabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 12284
    metabolic process 7837
      organic substance metabolic process 7548
        organic cyclic compound metabolic process 4192
          nucleobase-containing compound metabolic process 3862
            nucleobase-containing small molecule metabolic process 447
              nucleoside phosphate metabolic process 407
                nucleotide metabolic process 403
                  pyridine nucleotide metabolic process 67
                    nicotinamide nucleotide metabolic process 67
                      NADP metabolic process 41
                        NADP biosynthetic process 3
                        NADP catabolic process 2
                        NADPH oxidation 9
                        NADPH regeneration + 19
                        regulation of NADP metabolic process + 7
paths to the root