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ONTOLOGY REPORT - ANNOTATIONS


Term:NADP metabolic process
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Accession:GO:0006739 term browser browse the term
Definition:The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
Synonyms:exact_synonym: NADP metabolism;   NADPH metabolic process;   NADPH metabolism;   nicotinamide adenine dinucleotide phosphate metabolic process;   nicotinamide adenine dinucleotide phosphate metabolism;   oxidized NADP metabolic process;   oxidized NADP metabolism;   oxidized nicotinamide adenine dinucleotide phosphate metabolic process;   oxidized nicotinamide adenine dinucleotide phosphate metabolism;   reduced NADP metabolic process;   reduced NADP metabolism;   reduced nicotinamide adenine dinucleotide phosphate metabolic process;   reduced nicotinamide adenine dinucleotide phosphate metabolism
 related_synonym: NAD phosphorylation and dephosphorylation


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NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCXR dicarbonyl and L-xylulose reductase acts_upstream_of_or_within ISO (MGI:2179664|PMID:11882650) MGI PMID:11882650 MGI:2179664 NCBI chr17:76,439,645...76,442,282
Ensembl chr17:82,145,224...82,147,257
JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:11744609) BHF-UCL PMID:11744609 NCBI chr 1:146,678,858...146,704,831
Ensembl chr 1:150,393,061...150,417,295
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:15858258) UniProt PMID:15858258 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G GCK glucokinase acts_upstream_of_or_within ISO (MGI:3691164|PMID:9873043) MGI PMID:9873043 MGI:3691164 NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase ISO RGD PMID:6813321 RGD:1641956 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631
JBrowse link
G LOC100977566 cytochrome b5 reductase 4 ISO NADPH oxidation RGD PMID:11913972 RGD:632262 NCBI chr 6:81,756,292...81,864,365
Ensembl chr 6:85,030,058...85,130,948
JBrowse link
G NOCT nocturnin involved_in ISO (PMID:31147539) UniProt PMID:31147539 NCBI chr 4:131,378,656...131,409,711
Ensembl chr 4:142,691,169...142,719,514
JBrowse link
G PGD phosphogluconate dehydrogenase ISO RGD PMID:6813321 RGD:1641956 NCBI chr 1:9,159,412...9,180,740
Ensembl chr 1:10,385,087...10,408,078
JBrowse link
G TP53I3 tumor protein p53 inducible protein 3 involved_in ISO (PMID:19349281) UniProt PMID:19349281 NCBI chr2A:24,075,334...24,083,968
Ensembl chr2A:24,172,607...24,180,906
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:85983|PMID:9067418)
(MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:54902|PMID:7439685), (MGI:87492|PMID:9169132)
(MGI:3522057|PMID:15271799)
MGI PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO RGD PMID:21641335 RGD:11522736 NCBI chr15:68,771,050...68,790,523
Ensembl chr15:87,972,889...87,991,276
JBrowse link
G NADK NAD kinase ISO RGD PMID:22550069 RGD:13703105 NCBI chr 1:462,860...485,203
Ensembl chr 1:1,619,270...1,642,269
JBrowse link
NADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT12 nudix hydrolase 12 involved_in
acts_upstream_of_or_within
ISO (PMID:12790796) MGI PMID:12790796 NCBI chr 5:98,903,740...98,917,763
Ensembl chr 5:104,601,373...104,617,925
JBrowse link
G NUDT13 nudix hydrolase 13 involved_in ISO (MGI:6368098|PMID:28755312) UniProt PMID:28755312 MGI:6368098 NCBI chr10:69,656,828...69,696,769
Ensembl chr10:72,118,281...72,139,221
JBrowse link
NADPH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FDX1 ferredoxin 1 ISO RGD PMID:10525147 RGD:727285 NCBI chr11:105,311,613...105,345,414 JBrowse link
G FDXR ferredoxin reductase ISO RGD PMID:10525147 RGD:727285 NCBI chr17:68,808,123...68,818,642
Ensembl chr17:74,364,343...74,374,852
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 involved_in ISO (PMID:15144220) BHF-UCL PMID:15144220 NCBI chr 1:146,742,505...146,778,560
Ensembl chr 1:150,456,729...150,492,527
JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:15144220), (PMID:9804831) UniProt PMID:9804831 PMID:15144220 NCBI chr 1:146,678,858...146,704,831
Ensembl chr 1:150,393,061...150,417,295
JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 involved_in ISO (PMID:26771671) UniProt PMID:26771671 NCBI chr 1:122,605,677...122,648,325
Ensembl chr 1:112,881,859...112,921,194
JBrowse link
G KCNAB2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 involved_in ISO PMID:18672894 UniProt PMID:18672894 RGD:10047329 NCBI chr 1:4,755,412...4,866,424
Ensembl chr 1:6,013,072...6,120,438
JBrowse link
G LOC100977237 thioredoxin reductase 1, cytoplasmic ISO RGD PMID:19054767 RGD:5133716 NCBI chr12:101,862,703...101,925,104
Ensembl chr12:105,187,128...105,321,112
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:29444417 RGD:25823192 NCBI chr16:50,090,696...50,106,495
Ensembl chr16:69,470,288...69,489,731
JBrowse link
G PRDX5 peroxiredoxin 5 involved_in ISO (PMID:10751410) UniProt PMID:10751410 NCBI chr11:59,675,138...59,678,804
Ensembl chr11:63,020,097...63,023,624
JBrowse link
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:17516514) BHF-UCL PMID:17516514 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G NNT nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chr 5:66,662,249...66,772,352
Ensembl chr 5:71,719,257...71,823,242
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:2297768) RGD
BHF-UCL
PMID:2297768 PMID:2843500 RGD:1599574 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase acts_upstream_of_or_within ISO (MGI:2668276|PMID:12831846) MGI PMID:12831846 MGI:2668276 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631
JBrowse link
G PGD phosphogluconate dehydrogenase ISO RGD PMID:2843500 RGD:1599574 NCBI chr 1:9,159,412...9,180,740
Ensembl chr 1:10,385,087...10,408,078
JBrowse link
G PGLS 6-phosphogluconolactonase involved_in ISO (PMID:10518023) UniProt PMID:10518023 NCBI chr19:16,998,851...17,008,558
Ensembl chr19:17,971,544...17,980,431
JBrowse link
G RPE ribulose-5-phosphate-3-epimerase involved_in ISO (PMID:20923965) RGD
UniProt
PMID:2843500 PMID:20923965 RGD:1599574 NCBI chr2B:97,260,348...97,282,397 JBrowse link
G RPIA ribose 5-phosphate isomerase A ISO RGD PMID:2843500 RGD:1599574 NCBI chr2A:87,823,741...87,880,061
Ensembl chr2A:89,731,335...89,787,512
JBrowse link
G TALDO1 transaldolase 1 ISO RGD PMID:2843500 RGD:1599574 NCBI chr11:764,864...782,548
Ensembl chr11:809,751...826,744
JBrowse link
G TKT transketolase involved_in ISO (PMID:20667822) RGD
UniProt
PMID:2843500 PMID:20667822 RGD:1599574 NCBI chr 3:53,168,426...53,199,003
Ensembl chr 3:54,389,549...54,420,704
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPE ribulose-5-phosphate-3-epimerase ISO RGD PMID:3079759 RGD:1641816 NCBI chr2B:97,260,348...97,282,397 JBrowse link
G RPIA ribose 5-phosphate isomerase A ISO RGD PMID:3079759 RGD:1641816 NCBI chr2A:87,823,741...87,880,061
Ensembl chr2A:89,731,335...89,787,512
JBrowse link
G SHPK sedoheptulokinase involved_in ISO (MGI:5428058|PMID:22682222) UniProt PMID:22682222 MGI:5428058 NCBI chr17:3,657,764...3,686,791 JBrowse link
G TALDO1 transaldolase 1 ISO RGD PMID:3079759 PMID:8477719 RGD:1641803 RGD:1641816 NCBI chr11:764,864...782,548
Ensembl chr11:809,751...826,744
JBrowse link
G TKT transketolase ISO RGD PMID:3079759 PMID:16116031 RGD:1580394 RGD:1641816 NCBI chr 3:53,168,426...53,199,003
Ensembl chr 3:54,389,549...54,420,704
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO (PMID:2420826) RGD
BHF-UCL
PMID:2420826 PMID:9794092 RGD:1641793 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in ISO (PMID:18628520), (PMID:23132696) UniProt PMID:18628520 PMID:23132696 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631
JBrowse link
G PGD phosphogluconate dehydrogenase involved_in ISO (PMID:3858849) RGD
UniProt
PMID:3858849 PMID:9794092 RGD:1641793 NCBI chr 1:9,159,412...9,180,740
Ensembl chr 1:10,385,087...10,408,078
JBrowse link
G PGLS 6-phosphogluconolactonase ISO RGD PMID:971315 RGD:2311501 NCBI chr19:16,998,851...17,008,558
Ensembl chr19:17,971,544...17,980,431
JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ME1 malic enzyme 1 involved_in ISO (PMID:23334421) CACAO PMID:23334421 NCBI chr 6:81,107,569...81,320,050
Ensembl chr 6:84,382,732...84,595,701
JBrowse link
G ME2 malic enzyme 2 involved_in ISO (PMID:23334421) CACAO PMID:23334421 NCBI chr18:44,250,067...44,319,206
Ensembl chr18:47,613,446...47,665,330
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:16234247 RGD:1625062 NCBI chr 1:185,262,599...185,311,417
Ensembl chr 1:190,086,449...190,116,765
JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chr10:94,048,829...94,056,082
Ensembl chr10:97,542,558...97,549,867
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) UniProt PMID:25928429 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    metabolic process 7931
      NADP metabolic process 34
        NADP biosynthetic process 3
        NADP catabolic process 2
        NADPH oxidation 9
        NADPH regeneration + 14
        regulation of NADP metabolic process + 6
paths to the root