Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:NADP metabolic process
go back to main search page
Accession:GO:0006739 term browser browse the term
Definition:The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
Synonyms:exact_synonym: NADP metabolism;   NADPH metabolic process;   NADPH metabolism;   nicotinamide adenine dinucleotide phosphate metabolic process;   nicotinamide adenine dinucleotide phosphate metabolism;   oxidized NADP metabolic process;   oxidized NADP metabolism;   oxidized nicotinamide adenine dinucleotide phosphate metabolic process;   oxidized nicotinamide adenine dinucleotide phosphate metabolism;   reduced NADP metabolic process;   reduced NADP metabolism;   reduced nicotinamide adenine dinucleotide phosphate metabolic process;   reduced nicotinamide adenine dinucleotide phosphate metabolism
 related_synonym: NAD phosphorylation and dephosphorylation


show annotations for term's descendants           Sort by:
 
NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5r4 cytochrome b5 reductase 4 IDA NADPH oxidation RGD PMID:11913972 RGD:632262 NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase acts_upstream_of_or_within ISO (MGI:2179664|PMID:11882650) RGD PMID:11882650 MGI:2179664 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO (PMID:11744609) RGD PMID:11744609 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO
ISS
(PMID:15858258)
GO_REF:0000024
RGD
UniProt
PMID:15858258 GO_REF:0000024 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gck glucokinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3691164|PMID:9873043)
Ensembl
RGD
PMID:9873043 GO_REF:0000107 MGI:3691164 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IDA RGD PMID:6813321 RGD:1641956 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Noct nocturnin involved_in ISS
ISO
GO_REF:0000024
(PMID:31147539)
UniProt
RGD
PMID:31147539 GO_REF:0000024 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Pgd phosphogluconate dehydrogenase IDA RGD PMID:6813321 RGD:1641956 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 involved_in ISO (PMID:19349281) RGD PMID:19349281 NCBI chr13:69,612,605...69,655,018
Ensembl chr13:69,620,792...69,652,475
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO MGI:2182739 (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3522057|PMID:15271799), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:54902|PMID:7439685), (MGI:85983|PMID:9067418), (MGI:87492|PMID:9169132) RGD PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Nadk NAD kinase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069 PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:166,145,708...166,176,328
Ensembl chr 5:166,145,481...166,176,322
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial involved_in IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 2:58,117,674...58,159,815
Ensembl chr 2:58,117,674...58,159,808
JBrowse link
NADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt12 nudix hydrolase 12 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:12790796)
PMID:21873635
RGD PMID:12790796 PMID:21873635 RGD:13792537 NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039
JBrowse link
G Nudt13 nudix hydrolase 13 involved_in ISO (MGI:6368098|PMID:28755312) RGD PMID:28755312 MGI:6368098 NCBI chr15:4,001,787...4,022,404
Ensembl chr15:4,001,794...4,022,293
JBrowse link
G Nudt17 nudix hydrolase 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:184,241,468...184,243,960
Ensembl chr 2:184,241,468...184,243,960
JBrowse link
NADPH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 IDA RGD PMID:10525147 RGD:727285 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Fdxr ferredoxin reductase IDA RGD PMID:10525147 RGD:727285 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 involved_in ISO (PMID:15144220) RGD PMID:15144220 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:15144220), (PMID:9804831)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9804831 PMID:15144220 GO_REF:0000024 GO_REF:0000107 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26771671)
UniProt
Ensembl
RGD
PMID:26771671 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 involved_in IDA PMID:18672894 UniProt PMID:18672894 RGD:10047329 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IDA RGD PMID:29444417 RGD:25823192 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Prdx5 peroxiredoxin 5 involved_in ISO (PMID:10751410) RGD PMID:10751410 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Txnrd1 thioredoxin reductase 1 IDA RGD PMID:19054767 RGD:5133716 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
NADPH regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO (PMID:17516514) RGD PMID:17516514 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22198343 PMID:21873635 RGD:13513982, RGD:13792537 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) RGD PMID:21336310 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in IDA
ISO
(PMID:2297768) RGD PMID:2297768 PMID:2843500 RGD:1599574 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) acts_upstream_of_or_within ISO (MGI:2668276|PMID:12831846) RGD PMID:12831846 MGI:2668276 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Kif1b kinesin family member 1B involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in IDA
ISS
GO_REF:0000024 UniProt PMID:2843500 GO_REF:0000024, RGD:1599574 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pgls 6-phosphogluconolactonase involved_in ISO
IEA
(PMID:10518023)
GO_REF:0000041
RGD
UniProt
PMID:10518023 GO_REF:0000041 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase involved_in IDA
ISO
(PMID:20923965) RGD PMID:20923965 PMID:2843500 RGD:1599574 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591
JBrowse link
G Rpia ribose 5-phosphate isomerase A IDA RGD PMID:2843500 RGD:1599574 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
JBrowse link
G Taldo1 transaldolase 1 IDA RGD PMID:2843500 RGD:1599574 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Tkt transketolase involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:20667822)
Ensembl
RGD
PMID:20667822 PMID:2843500 GO_REF:0000107, RGD:1599574 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:3079759 PMID:21873635 RGD:1641816, RGD:13792537 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591
JBrowse link
G Rpia ribose 5-phosphate isomerase A involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:3079759 PMID:21873635 RGD:1641816, RGD:13792537 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
JBrowse link
G Shpk sedoheptulokinase involved_in ISO (MGI:5428058|PMID:22682222) RGD PMID:22682222 MGI:5428058 NCBI chr10:57,817,551...57,841,981
Ensembl chr10:57,817,629...57,841,980
JBrowse link
G Taldo1 transaldolase 1 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:8477719 PMID:21873635 PMID:3079759 RGD:1641803, RGD:13792537, RGD:1641816 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Tkt transketolase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16116031 PMID:21873635 PMID:3079759 RGD:1580394, RGD:13792537, RGD:1641816 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase involved_in IMP
ISO
(PMID:2420826) RGD PMID:2420826 PMID:9794092 RGD:1641793 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) involved_in ISO (PMID:18628520), (PMID:23132696) RGD PMID:18628520 PMID:23132696 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Pgd phosphogluconate dehydrogenase involved_in IMP
ISO
IBA
(PMID:3858849)
PMID:21873635
RGD PMID:3858849 PMID:9794092 PMID:21873635 RGD:1641793, RGD:13792537 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pgls 6-phosphogluconolactonase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:971315 PMID:21873635 RGD:2311501, RGD:13792537 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Me1 malic enzyme 1 involved_in ISO
IEA
(PMID:23334421)
GO_REF:0000107
RGD
Ensembl
PMID:23334421 GO_REF:0000107 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Me2 malic enzyme 2 involved_in ISO (PMID:23334421) RGD PMID:23334421 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:16234247 RGD:1625062 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) RGD PMID:12189148 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in IBA
ISO
PMID:21873635
(PMID:25928429)
RGD PMID:25928429 PMID:21873635 RGD:13792537 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      NADP metabolic process 38
        NADP biosynthetic process 4
        NADP catabolic process 3
        NADPH oxidation 9
        NADPH regeneration + 15
        regulation of NADP metabolic process + 6
paths to the root