Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:NADP metabolic process
go back to main search page
Accession:GO:0006739 term browser browse the term
Definition:The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
Synonyms:exact_synonym: NADP metabolism;   NADPH metabolic process;   NADPH metabolism;   nicotinamide adenine dinucleotide phosphate metabolic process;   nicotinamide adenine dinucleotide phosphate metabolism;   oxidized NADP metabolic process;   oxidized NADP metabolism;   oxidized nicotinamide adenine dinucleotide phosphate metabolic process;   oxidized nicotinamide adenine dinucleotide phosphate metabolism;   reduced NADP metabolic process;   reduced NADP metabolism;   reduced nicotinamide adenine dinucleotide phosphate metabolic process;   reduced nicotinamide adenine dinucleotide phosphate metabolism
 related_synonym: NAD phosphorylation and dephosphorylation


show annotations for term's descendants           Sort by:
 
NADP metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5r4 cytochrome b5 reductase 4 IDA NADPH oxidation RGD PMID:11913972 RGD:632262 NCBI chr 8:94,693,273...94,757,989
Ensembl chr 8:94,693,290...94,757,988
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase ISO (MGI:MGI:2179664|PMID:11882650) RGD PMID:11882650 MGI:MGI:2179664 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 ISO (PMID:11744609) RGD PMID:11744609 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO
ISS
(PMID:15858258)
GO_REF:0000024
RGD
UniProt
PMID:15858258 GO_REF:0000024 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gck glucokinase ISO
IEA
(MGI:MGI:3691164|PMID:9873043)
GO_REF:0000107
RGD
Ensembl
PMID:9873043 GO_REF:0000107, MGI:MGI:3691164 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IDA RGD PMID:6813321 RGD:1641956 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Noct nocturnin ISS
ISO
GO_REF:0000024
(PMID:31147539)
UniProt
RGD
PMID:31147539 GO_REF:0000024 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Pgd phosphogluconate dehydrogenase IDA RGD PMID:6813321 RGD:1641956 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 ISO (PMID:19349281) RGD PMID:19349281 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO MGI:MGI:2182739 (MGI:MGI:1097071|PMID:9330624), (MGI:MGI:1202104|PMID:9539108), (MGI:MGI:1261671|PMID:9627357), (MGI:MGI:1349468|PMID:3377761), (MGI:MGI:2387959|PMID:10627286), (MGI:MGI:3522057|PMID:15271799), (MGI:MGI:3607389|PMID:14757696), (MGI:MGI:3694178|PMID:15998684), (MGI:MGI:49164|PMID:1953691), (MGI:MGI:54902|PMID:7439685), (MGI:MGI:85983|PMID:9067418), (MGI:MGI:87492|PMID:9169132) RGD PMID:1953691, PMID:3377761, PMID:7439685, PMID:9067418, PMID:9169132, PMID:9330624, PMID:9539108, PMID:9627357, PMID:10627286, PMID:14757696, PMID:15271799, PMID:15998684 MGI:MGI:1097071, MGI:MGI:1202104, MGI:MGI:1261671, MGI:MGI:1349468, MGI:MGI:2387959, MGI:MGI:3522057, MGI:MGI:3607389, MGI:MGI:3694178, MGI:MGI:49164, MGI:MGI:54902, MGI:MGI:85983, MGI:MGI:87492 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:21641335 RGD:11522736 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Nadk NAD kinase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22550069, PMID:21873635 RGD:13703105, RGD:13792537 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nadk2 NAD kinase 2, mitochondrial IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002, GO_REF:0000104 NCBI chr 2:58,462,588...58,504,735
Ensembl chr 2:58,462,588...58,504,728
JBrowse link
NADP catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt12 nudix hydrolase 12 ISO
IBA
(PMID:12790796)
PMID:21873635
RGD PMID:12790796, PMID:21873635 RGD:13792537 NCBI chr 9:105,680,603...105,693,374
Ensembl chr 9:105,680,670...105,693,357
JBrowse link
G Nudt13 nudix hydrolase 13 ISO (MGI:MGI:6368098|PMID:28755312) RGD PMID:28755312 MGI:MGI:6368098 NCBI chr15:4,434,341...4,454,871
Ensembl chr15:4,434,313...4,454,958
JBrowse link
G Nudt17 nudix hydrolase 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:198,831,546...198,836,191
Ensembl chr 2:198,831,546...198,834,925
JBrowse link
NADPH oxidation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdx1 ferredoxin 1 IDA RGD PMID:10525147 RGD:727285 NCBI chr 8:56,373,729...56,393,199
Ensembl chr 8:56,373,723...56,393,233
JBrowse link
G Fdxr ferredoxin reductase IDA RGD PMID:10525147 RGD:727285 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 ISO (PMID:15144220) RGD PMID:15144220 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 IEA
ISO
ISS
GO_REF:0000107
(PMID:15144220), (PMID:9804831)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9804831, PMID:15144220 GO_REF:0000024, GO_REF:0000107 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 ISO
IEA
ISS
(PMID:26771671)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26771671 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 IDA PMID:18672894 UniProt PMID:18672894 RGD:10047329 NCBI chr 5:169,570,327...169,658,875
Ensembl chr 5:169,572,517...169,658,875
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IDA RGD PMID:29444417 RGD:25823192 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Prdx5 peroxiredoxin 5 ISO (PMID:10751410) RGD PMID:10751410 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Txnrd1 thioredoxin reductase 1 IDA RGD PMID:19054767 RGD:5133716 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
NADPH regeneration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO (PMID:17516514) RGD PMID:17516514 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:22198343, PMID:21873635 RGD:13513982, RGD:13792537 NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 ISO (PMID:21336310) RGD PMID:21336310 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
pentose-phosphate shunt term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase IDA
ISO
(PMID:2297768) RGD PMID:2297768, PMID:2843500 RGD:1599574 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) ISO (MGI:MGI:2668276|PMID:12831846) RGD PMID:12831846 MGI:MGI:2668276 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Kif1b kinesin family member 1B IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Pgd phosphogluconate dehydrogenase IDA
ISS
GO_REF:0000024 UniProt PMID:2843500 GO_REF:0000024, RGD:1599574 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgls 6-phosphogluconolactonase ISO
IEA
(PMID:10518023)
GO_REF:0000041
RGD
UniProt
PMID:10518023 GO_REF:0000041 NCBI chr16:20,020,444...20,025,930
Ensembl chr16:20,020,444...20,025,930
JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase IDA
ISO
(PMID:20923965) RGD PMID:20923965, PMID:2843500 RGD:1599574 NCBI chr 9:73,687,684...73,713,643
Ensembl chr 9:73,687,743...73,711,571
JBrowse link
G Rpia ribose 5-phosphate isomerase A IDA RGD PMID:2843500 RGD:1599574 NCBI chr 4:98,568,028...98,593,664
Ensembl chr 4:98,568,028...98,593,664
JBrowse link
G Taldo1 transaldolase 1 IDA RGD PMID:2843500 RGD:1599574 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tkt transketolase IDA
IEA
ISO
GO_REF:0000107
(PMID:20667822)
Ensembl
RGD
PMID:20667822, PMID:2843500 GO_REF:0000107, RGD:1599574 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
pentose-phosphate shunt, non-oxidative branch term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:3079759, PMID:21873635 RGD:1641816, RGD:13792537 NCBI chr 9:73,687,684...73,713,643
Ensembl chr 9:73,687,743...73,711,571
JBrowse link
G Rpia ribose 5-phosphate isomerase A IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:3079759, PMID:21873635 RGD:1641816, RGD:13792537 NCBI chr 4:98,568,028...98,593,664
Ensembl chr 4:98,568,028...98,593,664
JBrowse link
G Shpk sedoheptulokinase ISO (MGI:MGI:5428058|PMID:22682222) RGD PMID:22682222 MGI:MGI:5428058 NCBI chr10:59,765,328...59,789,676
Ensembl chr10:59,765,258...59,789,678
JBrowse link
G Taldo1 transaldolase 1 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:8477719, PMID:21873635, PMID:3079759 RGD:1641803, RGD:13792537, RGD:1641816 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tkt transketolase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16116031, PMID:21873635, PMID:3079759 RGD:1580394, RGD:13792537, RGD:1641816 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
pentose-phosphate shunt, oxidative branch term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase IMP
ISO
(PMID:2420826) RGD PMID:2420826, PMID:9794092 RGD:1641793 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) ISO (PMID:18628520), (PMID:23132696) RGD PMID:18628520, PMID:23132696 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Pgd phosphogluconate dehydrogenase IMP
IBA
ISO
PMID:21873635
(PMID:3858849)
RGD PMID:3858849, PMID:9794092, PMID:21873635 RGD:1641793, RGD:13792537 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgls 6-phosphogluconolactonase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:971315, PMID:21873635 RGD:2311501, RGD:13792537 NCBI chr16:20,020,444...20,025,930
Ensembl chr16:20,020,444...20,025,930
JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Me1 malic enzyme 1 ISO
IEA
(PMID:23334421)
GO_REF:0000107
RGD
Ensembl
PMID:23334421 GO_REF:0000107 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Me2 malic enzyme 2 ISO (PMID:23334421) RGD PMID:23334421 NCBI chr18:69,737,515...69,784,099
Ensembl chr18:69,738,686...69,784,099
JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:16234247 RGD:1625062 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Pgam1 phosphoglycerate mutase 1 ISO (PMID:12189148) RGD PMID:12189148 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase ISO
IBA
(PMID:25928429)
PMID:21873635
RGD PMID:25928429, PMID:21873635 RGD:13792537 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      NADP metabolic process 38
        NADP biosynthetic process 4
        NADP catabolic process 3
        NADPH oxidation 9
        NADPH regeneration + 15
        regulation of NADP metabolic process + 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.